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Items: 1 to 50 of 171

1.

Measurement of DNA damage with the comet assay in high-prevalence diseases: current status and future directions.

Møller P, Stopper H, Collins AR.

Mutagenesis. 2019 Jul 11. pii: gez018. doi: 10.1093/mutage/gez018. [Epub ahead of print]

PMID:
31294794
2.

Protective effects of tricetinidin against oxidative stress inducers in rat kidney cells: A comparison with delphinidin and standard antioxidants.

Bankoglu EE, Broscheit J, Arnaudov T, Roewer N, Stopper H.

Food Chem Toxicol. 2018 Nov;121:549-557. doi: 10.1016/j.fct.2018.09.058. Epub 2018 Sep 25.

PMID:
30266311
3.

Decreased Chromosomal Damage in Lymphocytes of Obese Patients After Bariatric Surgery.

Bankoglu EE, Arnold C, Hering I, Hankir M, Seyfried F, Stopper H.

Sci Rep. 2018 Jul 25;8(1):11195. doi: 10.1038/s41598-018-29581-6.

4.
5.

Increased exposure to pesticides and colon cancer: Early evidence in Brazil.

Martin FL, Martinez EZ, Stopper H, Garcia SB, Uyemura SA, Kannen V.

Chemosphere. 2018 Oct;209:623-631. doi: 10.1016/j.chemosphere.2018.06.118. Epub 2018 Jun 20.

PMID:
29957523
6.

The Biological Activity of the Novel Vinca Alkaloids 4-chlorochablastine and 4-chlorochacristine.

Montag G, Stopper H, Ngo QA, Hintzsche H.

Curr Cancer Drug Targets. 2019;19(3):222-230. doi: 10.2174/1568009618666180430142233.

PMID:
29714145
7.

Metabolomic profiling and biological investigation of the marine sponge-derived bacterium Rhodococcus sp. UA13.

Elsayed Y, Refaat J, Abdelmohsen UR, Othman EM, Stopper H, Fouad MA.

Phytochem Anal. 2018 Nov;29(6):543-548. doi: 10.1002/pca.2765. Epub 2018 Apr 19.

PMID:
29672972
8.

Induction of micronuclei by four cytostatic compounds in human hematopoietic stem cells and human lymphoblastoid TK6 cells.

Hintzsche H, Montag G, Stopper H.

Sci Rep. 2018 Feb 20;8(1):3371. doi: 10.1038/s41598-018-21680-8. Erratum in: Sci Rep. 2018 Jul 13;8(1):10901.

9.

Reduction of DNA damage in peripheral lymphocytes of obese patients after bariatric surgery-mediated weight loss.

Bankoglu EE, Seyfried F, Arnold C, Soliman A, Jurowich C, Germer CT, Otto C, Stopper H.

Mutagenesis. 2018 Feb 24;33(1):61-67. doi: 10.1093/mutage/gex040.

PMID:
29294093
10.

Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro.

Awad E, Othman EM, Stopper H.

Molecules. 2017 Dec 12;22(12). pii: E2207. doi: 10.3390/molecules22122207.

11.

Isolation of Petrocidin A, a New Cytotoxic Cyclic Dipeptide from the Marine Sponge-Derived Bacterium Streptomyces sp. SBT348.

Cheng C, Othman EM, Stopper H, Edrada-Ebel R, Hentschel U, Abdelmohsen UR.

Mar Drugs. 2017 Dec 6;15(12). pii: E383. doi: 10.3390/md15120383.

12.

Mapping the pharmaceutical design space by amorphous ionic liquid strategies.

Wiest J, Saedtler M, Balk A, Merget B, Widmer T, Bruhn H, Raccuglia M, Walid E, Picard F, Stopper H, Dekant W, Lühmann T, Sotriffer C, Galli B, Holzgrabe U, Meinel L.

J Control Release. 2017 Dec 28;268:314-322. doi: 10.1016/j.jconrel.2017.10.040. Epub 2017 Oct 31.

PMID:
29097303
13.

A Perspective Discussion on Rising Pesticide Levels and Colon Cancer Burden in Brazil.

Uyemura SA, Stopper H, Martin FL, Kannen V.

Front Public Health. 2017 Oct 16;5:273. doi: 10.3389/fpubh.2017.00273. eCollection 2017.

14.

Isolation of a novel compound (MIMO2) from the methanolic extract of Moringa oleifera leaves: protective effects against vanadium-induced cytotoxity.

Igado OO, Glaser J, Ramos-Tirado M, Bankoğlu EE, Atiba FA, Holzgrabe U, Stopper H, Olopade JO.

Drug Chem Toxicol. 2018 Jul;41(3):249-258. doi: 10.1080/01480545.2017.1366504. Epub 2017 Sep 19.

PMID:
28925291
15.

Image-based modeling and scoring of Howell-Jolly Bodies in human erythrocytes.

Angay O, Friedrich M, Pinnecker J, Hintzsche H, Stopper H, Hempel K, Heinze KG.

Cytometry A. 2018 Mar;93(3):305-313. doi: 10.1002/cyto.a.23123. Epub 2017 May 24.

16.

Fate of micronuclei and micronucleated cells.

Hintzsche H, Hemmann U, Poth A, Utesch D, Lott J, Stopper H; Working Group “In vitro micronucleus test”, Gesellschaft für Umwelt-Mutationsforschung (GUM, German-speaking section of the European Environmental Mutagenesis and Genomics Society EEMGS).

Mutat Res. 2017 Jan - Mar;771:85-98. doi: 10.1016/j.mrrev.2017.02.002. Epub 2017 Feb 13. Review.

PMID:
28342454
17.

Marine Sponge-Derived Streptomyces sp. SBT343 Extract Inhibits Staphylococcal Biofilm Formation.

Balasubramanian S, Othman EM, Kampik D, Stopper H, Hentschel U, Ziebuhr W, Oelschlaeger TA, Abdelmohsen UR.

Front Microbiol. 2017 Feb 16;8:236. doi: 10.3389/fmicb.2017.00236. eCollection 2017.

18.

The Plant Hormone Cytokinin Confers Protection against Oxidative Stress in Mammalian Cells.

Othman EM, Naseem M, Awad E, Dandekar T, Stopper H.

PLoS One. 2016 Dec 22;11(12):e0168386. doi: 10.1371/journal.pone.0168386. eCollection 2016.

19.

Role of PTEN in Oxidative Stress and DNA Damage in the Liver of Whole-Body Pten Haplodeficient Mice.

Bankoglu EE, Tschopp O, Schmitt J, Burkard P, Jahn D, Geier A, Stopper H.

PLoS One. 2016 Nov 28;11(11):e0166956. doi: 10.1371/journal.pone.0166956. eCollection 2016.

20.

IR and IGF-1R expression affects insulin induced proliferation and DNA damage.

Othman EM, Altabaa T, Hintzsche H, Stopper H.

Toxicol In Vitro. 2017 Mar;39:68-74. doi: 10.1016/j.tiv.2016.11.011. Epub 2016 Nov 22.

PMID:
27884723
21.

Effect of Radiofrequency Radiation on Human Hematopoietic Stem Cells.

Gläser K, Rohland M, Kleine-Ostmann T, Schrader T, Stopper H, Hintzsche H.

Radiat Res. 2016 Nov;186(5):455-465. Epub 2016 Oct 6.

PMID:
27710704
22.

DNA Damage in Chronic Kidney Disease: Evaluation of Clinical Biomarkers.

Schupp N, Stopper H, Heidland A.

Oxid Med Cell Longev. 2016;2016:3592042. doi: 10.1155/2016/3592042. Epub 2016 May 25. Review.

23.

Impact of weight loss induced by gastric bypass or caloric restriction on oxidative stress and genomic damage in obese Zucker rats.

Bankoglu EE, Seyfried F, Rotzinger L, Nordbeck A, Corteville C, Jurowich C, Germer CT, Otto C, Stopper H.

Free Radic Biol Med. 2016 May;94:208-17. doi: 10.1016/j.freeradbiomed.2016.02.033. Epub 2016 Mar 3.

PMID:
26939878
24.

Cytogenetic Effects of Chronic Methylphenidate Treatment and Chronic Social Stress in Adults with Attention-Deficit/Hyperactivity Disorder.

Kittel-Schneider S, Spiegel S, Renner T, Romanos M, Reif A, Reichert S, Heupel J, Schnetzler L, Stopper H, Jacob C.

Pharmacopsychiatry. 2016 Jul;49(4):146-54. doi: 10.1055/s-0035-1569361. Epub 2016 Feb 29.

PMID:
26926233
25.

Metformin Protects Kidney Cells From Insulin-Mediated Genotoxicity In Vitro and in Male Zucker Diabetic Fatty Rats.

Othman EM, Oli RG, Arias-Loza PA, Kreissl MC, Stopper H.

Endocrinology. 2016 Feb;157(2):548-59. doi: 10.1210/en.2015-1572. Epub 2015 Dec 4.

PMID:
26636185
26.

Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.

Abraham SK, Khandelwal N, Hintzsche H, Stopper H.

Mutagenesis. 2016 Jan;31(1):27-33. doi: 10.1093/mutage/gev048. Epub 2015 Jul 7.

PMID:
26152226
27.

Genotoxic activity of the new pharmaceutical FS-1 in Salmonella/microsome test and mouse lymphoma L5178Y cells.

Ilin A, Kulmanov M, Nersesyan A, Stopper H.

J BUON. 2015 Mar-Apr;20(2):595-601.

28.

Oncostatic effects of fluoxetine in experimental colon cancer models.

Kannen V, Garcia SB, Silva WA Jr, Gasser M, Mönch R, Alho EJ, Heinsen H, Scholz CJ, Friedrich M, Heinze KG, Waaga-Gasser AM, Stopper H.

Cell Signal. 2015 Sep;27(9):1781-8. doi: 10.1016/j.cellsig.2015.05.008. Epub 2015 May 22.

PMID:
26004136
29.

Two new antioxidant actinosporin analogues from the calcium alginate beads culture of sponge-associated Actinokineospora sp. strain EG49.

Grkovic T, Abdelmohsen UR, Othman EM, Stopper H, Edrada-Ebel R, Hentschel U, Quinn RJ.

Bioorg Med Chem Lett. 2014 Nov 1;24(21):5089-92. doi: 10.1016/j.bmcl.2014.08.068. Epub 2014 Sep 6.

PMID:
25266784
30.

In vitro genotoxic and mutagenic evaluation of the aqueous extract of Codiaeum variegatum and its amoebicidal sub-fraction.

Mfotie Njoya E, Moundipa PF, Stopper H.

J Ethnopharmacol. 2014 Aug 8;155(1):823-9. doi: 10.1016/j.jep.2014.06.038. Epub 2014 Jun 24.

PMID:
24971796
31.

The contribution of neuronal-glial-endothelial-epithelial interactions to colon carcinogenesis.

Garcia SB, Stopper H, Kannen V.

Cell Mol Life Sci. 2014 Sep;71(17):3191-7. doi: 10.1007/s00018-014-1642-z. Epub 2014 May 22. Review.

PMID:
24848584
32.

Antidepressant fluoxetine and its potential against colon tumors.

Stopper H, Garcia SB, Waaga-Gasser AM, Kannen V.

World J Gastrointest Oncol. 2014 Jan 15;6(1):11-21. doi: 10.4251/wjgo.v6.i1.11. Review.

33.

Aldosterone activates transcription factor Nrf2 in kidney cells both in vitro and in vivo.

Queisser N, Oteiza PI, Link S, Hey V, Stopper H, Schupp N.

Antioxid Redox Signal. 2014 Nov 20;21(15):2126-42. doi: 10.1089/ars.2013.5565. Epub 2014 Mar 21.

34.

Signaling steps in the induction of genomic damage by insulin in colon and kidney cells.

Othman EM, Hintzsche H, Stopper H.

Free Radic Biol Med. 2014 Mar;68:247-57. doi: 10.1016/j.freeradbiomed.2013.12.010. Epub 2013 Dec 16.

PMID:
24355212
35.

Photohemolysis Sensitized by the Furocoumarin Derivative Alloimperatorin and its Hydroperoxide Photooxidation Product.

Kyagova A, Potapenko A, Möller M, Stopper H, Adam W.

Photochem Photobiol. 2014 Jan;90(1):162-70. doi: 10.1111/php.12184. Epub 2013 Nov 25.

PMID:
24117477
36.

Colon preneoplasia after carcinogen exposure is enhanced and colonic serotonergic system is suppressed by food deprivation.

Kannen V, Fernandes CR, Stopper H, Zanette DL, Ferreira FR, Frajacomo FT, Carvalho MC, Brandão ML, Elias Junior J, Jordão Junior AA, Uyemura SA, Waaga-Gasser AM, Garcia SB.

Toxicology. 2013 Oct 4;312:123-31. doi: 10.1016/j.tox.2013.08.014. Epub 2013 Aug 23.

PMID:
23978458
37.

Glucagon-like peptide 2 in colon carcinogenesis: possible target for anti-cancer therapy?

Kannen V, Garcia SB, Stopper H, Waaga-Gasser AM.

Pharmacol Ther. 2013 Jul;139(1):87-94. doi: 10.1016/j.pharmthera.2013.04.007. Epub 2013 Apr 11. Review.

PMID:
23583681
38.

Insulin mediated DNA damage in mammalian colon cells and human lymphocytes in vitro.

Othman EM, Leyh A, Stopper H.

Mutat Res. 2013 May-Jun;745-746:34-9. doi: 10.1016/j.mrfmmm.2013.03.006. Epub 2013 Mar 21.

PMID:
23524287
39.

Insulin-mediated oxidative stress and DNA damage in LLC-PK1 pig kidney cell line, female rat primary kidney cells, and male ZDF rat kidneys in vivo.

Othman EM, Kreissl MC, Kaiser FR, Arias-Loza PA, Stopper H.

Endocrinology. 2013 Apr;154(4):1434-43. doi: 10.1210/en.2012-1768. Epub 2013 Mar 1.

PMID:
23456362
40.

Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model.

Kannen V, Hintzsche H, Zanette DL, Silva WA Jr, Garcia SB, Waaga-Gasser AM, Stopper H.

PLoS One. 2012;7(11):e50043. doi: 10.1371/journal.pone.0050043. Epub 2012 Nov 27. Erratum in: PLoS One. 2013;8(6). doi: 10.1371/annotation/919e5cc0-39bb-4465-babe-d2bdf12e89ff.

41.

Terahertz radiation at 0.380 THz and 2.520 THz does not lead to DNA damage in skin cells in vitro.

Hintzsche H, Jastrow C, Heinen B, Baaske K, Kleine-Ostmann T, Schwerdtfeger M, Shakfa MK, Kärst U, Koch M, Schrader T, Stopper H.

Radiat Res. 2013 Jan;179(1):38-45. doi: 10.1667/RR3077.1. Epub 2012 Nov 26.

PMID:
23181591
42.

Antioxidant and anti-protease activities of diazepinomicin from the sponge-associated Micromonospora strain RV115.

Abdelmohsen UR, Szesny M, Othman EM, Schirmeister T, Grond S, Stopper H, Hentschel U.

Mar Drugs. 2012 Oct;10(10):2208-21. doi: 10.3390/md10102208. Epub 2012 Oct 8.

43.

Terahertz electromagnetic fields (0.106 THz) do not induce manifest genomic damage in vitro.

Hintzsche H, Jastrow C, Kleine-Ostmann T, Kärst U, Schrader T, Stopper H.

PLoS One. 2012;7(9):e46397. doi: 10.1371/journal.pone.0046397. Epub 2012 Sep 27.

44.

Hyperthermia-induced micronucleus formation in a human keratinocyte cell line.

Hintzsche H, Riese T, Stopper H.

Mutat Res. 2012 Oct-Nov;738-739:71-4. doi: 10.1016/j.mrfmmm.2012.08.004. Epub 2012 Sep 4.

PMID:
22974710
45.

Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4.

Fazeli G, Stopper H, Schinzel R, Ni CW, Jo H, Schupp N.

Mutagenesis. 2012 Nov;27(6):673-81. doi: 10.1093/mutage/ges033. Epub 2012 Jul 27.

46.

High-fat diet causes an imbalance in the colonic serotonergic system promoting adipose tissue enlargement and dysplasia in rats.

Kannen V, Zanette DL, Fernandes CR, Ferreira FR, Marini T, Carvalho MC, Brandão ML, Elias Junior J, Mauad FM, Silva WA Jr, Stopper H, Garcia SB.

Toxicol Lett. 2012 Sep 3;213(2):135-41. doi: 10.1016/j.toxlet.2012.06.014. Epub 2012 Jun 29.

PMID:
22750881
47.

Micronucleus formation kinetics in buccal mucosa cells of head and neck cancer patients undergoing radiotherapy.

Hintzsche H, Polat B, Schewe V, Djuzenova CS, Pfreundner L, Flentje M, Stopper H.

Toxicol Lett. 2012 Jul 7;212(1):33-7. doi: 10.1016/j.toxlet.2012.04.020. Epub 2012 May 4.

PMID:
22564757
48.

Patulin: Mechanism of genotoxicity.

Glaser N, Stopper H.

Food Chem Toxicol. 2012 May;50(5):1796-801. doi: 10.1016/j.fct.2012.02.096. Epub 2012 Mar 7.

PMID:
22425938
49.

900 MHz radiation does not induce micronucleus formation in different cell types.

Hintzsche H, Jastrow C, Kleine-Ostmann T, Schrader T, Stopper H.

Mutagenesis. 2012 Jul;27(4):477-83. doi: 10.1093/mutage/ges007. Epub 2012 Mar 13.

PMID:
22416057
50.

Analysis of in vitro chemoprevention of genotoxic damage by phytochemicals, as single agents or as combinations.

Abraham SK, Eckhardt A, Oli RG, Stopper H.

Mutat Res. 2012 May 15;744(2):117-24. doi: 10.1016/j.mrgentox.2012.01.011. Epub 2012 Mar 3.

PMID:
22405976

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