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Items: 1 to 50 of 118

1.

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444. doi: 10.1126/scitranslmed.aaf7444.

PMID:
29444979
2.

β3-Adrenergically induced glucose uptake in brown adipose tissue is independent of UCP1 presence or activity: Mediation through the mTOR pathway.

Olsen JM, Csikasz RI, Dehvari N, Lu L, Sandström A, Öberg AI, Nedergaard J, Stone-Elander S, Bengtsson T.

Mol Metab. 2017 Mar 30;6(6):611-619. doi: 10.1016/j.molmet.2017.02.006. eCollection 2017 Jun.

3.

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.

Cheng Q, Wållberg H, Grafström J, Lu L, Thorell JO, Hägg Olofsson M, Linder S, Johansson K, Tegnebratt T, Arnér ES, Stone-Elander S, Ahlzén HS, Ståhl S; Sel-tag imaging project.

EJNMMI Res. 2016 Dec;6(1):58. doi: 10.1186/s13550-016-0213-8. Epub 2016 Jul 7.

4.

A method for comparing intra-tumoural radioactivity uptake heterogeneity in preclinical positron emission tomography studies.

Grafström J, Ahlzén HS, Stone-Elander S.

EJNMMI Phys. 2015 Dec;2(1):19. doi: 10.1186/s40658-015-0124-1. Epub 2015 Sep 8.

5.

[11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET).

Gourand F, Amini N, Jia Z, Stone-Elander S, Guilloteau D, Barré L, Halldin C.

PLoS One. 2015 Sep 14;10(9):e0137160. doi: 10.1371/journal.pone.0137160. eCollection 2015.

6.

Evaluation of efficacy of a new MEK inhibitor, RO4987655, in human tumor xenografts by [(18)F] FDG-PET imaging combined with proteomic approaches.

Tegnebratt T, Ruge E, Bader S, Ishii N, Aida S, Yoshimura Y, Ooi CH, Lu L, Mitsios N, Meresse V, Mulder J, Pawlak M, Venturi M, Tessier J, Stone-Elander S.

EJNMMI Res. 2014 Dec;4(1):34. doi: 10.1186/s13550-014-0034-6. Epub 2014 Sep 9.

7.

Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.

Arnberg F, Grafström J, Lundberg J, Nikkhou-Aski S, Little P, Damberg P, Mitsios N, Mulder J, Lu L, Söderman M, Stone-Elander S, Holmin S.

Stroke. 2015 Mar;46(3):835-42. doi: 10.1161/STROKEAHA.114.008407. Epub 2015 Feb 5.

PMID:
25657187
8.

Comparison of methods for evaluating radiolabelled Annexin A5 uptake in pre-clinical PET oncological studies.

Grafström J, Stone-Elander S.

Nucl Med Biol. 2014 Nov-Dec;41(10):793-800. doi: 10.1016/j.nucmedbio.2014.07.003. Epub 2014 Aug 1.

9.

Visualization of angiogenesis during cancer development in the polyoma middle T breast cancer model: molecular imaging with (R)-[11C]PAQ.

Samén E, Lu L, Mulder J, Thorell JO, Damberg P, Tegnebratt T, Holmgren L, Rundqvist H, Stone-Elander S.

EJNMMI Res. 2014 Mar 26;4(1):17. doi: 10.1186/2191-219X-4-17.

10.

Selective intra-arterial administration of ¹⁸F-FDG to the rat brain -- effects on hemispheric uptake.

Arnberg F, Samén E, Lundberg J, Lu L, Grafström J, Söderman M, Stone-Elander S, Holmin S.

Neuroradiology. 2014 May;56(5):375-80. doi: 10.1007/s00234-014-1335-1. Epub 2014 Feb 14.

11.

Endovascular method for transplantation of insulin-producing cells to the pancreas parenchyma in swine.

Lundberg J, Stone-Elander S, Zhang XM, Korsgren O, Jonsson S, Holmin S.

Am J Transplant. 2014 Mar;14(3):694-700. doi: 10.1111/ajt.12601. Epub 2014 Feb 12.

12.

[18 F]FDG-PET imaging is an early non-invasive pharmacodynamic biomarker for a first-in-class dual MEK/Raf inhibitor, RO5126766 (CH5126766), in preclinical xenograft models.

Tegnebratt T, Lu L, Lee L, Meresse V, Tessier J, Ishii N, Harada N, Pisa P, Stone-Elander S.

EJNMMI Res. 2013 Sep 16;3(1):67. doi: 10.1186/2191-219X-3-67.

13.

Metabolism of epidermal growth factor receptor targeting probe [11C]PD153035: impact on biodistribution and tumor uptake in rats.

Samén E, Arnberg F, Lu L, Olofsson MH, Tegnebratt T, Thorell JO, Holmin S, Stone-Elander S.

J Nucl Med. 2013 Oct;54(10):1804-11. doi: 10.2967/jnumed.113.120493. Epub 2013 Sep 3.

14.

Site-specifically 11C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death.

Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, Johansson K, Ahlzén HS, Linder S, Arnér ES, Stone-Elander S.

Biochim Biophys Acta. 2013 Mar;1830(3):2562-73.

15.

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes.

Hagberg CE, Mehlem A, Falkevall A, Muhl L, Fam BC, Ortsäter H, Scotney P, Nyqvist D, Samén E, Lu L, Stone-Elander S, Proietto J, Andrikopoulos S, Sjöholm A, Nash A, Eriksson U.

Nature. 2012 Oct 18;490(7420):426-30. doi: 10.1038/nature11464. Epub 2012 Sep 26.

PMID:
23023133
16.

HER2-positive tumors imaged within 1 hour using a site-specifically 11C-labeled Sel-tagged affibody molecule.

Wållberg H, Grafström J, Cheng Q, Lu L, Martinsson Ahlzén HS, Samén E, Thorell JO, Johansson K, Dunås F, Olofsson MH, Stone-Elander S, Arnér ES, Ståhl S.

J Nucl Med. 2012 Sep;53(9):1446-53. doi: 10.2967/jnumed.111.102194. Epub 2012 Aug 7.

17.

Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts.

Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, Johansson K, Ahlzén HS, Stone-Elander S, Linder S, Arnér ES; Sel-tag Imaging Project.

PLoS One. 2012;7(8):e42151. doi: 10.1371/journal.pone.0042151. Epub 2012 Aug 1.

18.

Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells.

Buentke E, Nordström A, Lin H, Björklund AC, Laane E, Harada M, Lu L, Tegnebratt T, Stone-Elander S, Heyman M, Söderhäll S, Porwit A, Ostenson CG, Shoshan M, Tamm KP, Grandér D.

Blood Cancer J. 2011 Jul;1(7):e31. doi: 10.1038/bcj.2011.27. Epub 2011 Jul 29.

19.

Brief Report: alterations in cerebral blood flow as assessed by PET/CT in adults with autism spectrum disorder with normal IQ.

Pagani M, Manouilenko I, Stone-Elander S, Odh R, Salmaso D, Hatherly R, Brolin F, Jacobsson H, Larsson SA, Bejerot S.

J Autism Dev Disord. 2012 Feb;42(2):313-8. doi: 10.1007/s10803-011-1240-y.

PMID:
21487836
20.

Radiolabelled receptor-tyrosine-kinase targeting drugs for patient stratification and monitoring of therapy response: prospects and pitfalls.

Tolmachev V, Stone-Elander S, Orlova A.

Lancet Oncol. 2010 Oct;11(10):992-1000. doi: 10.1016/S1470-2045(10)70088-7. Epub 2010 Jul 26. Review.

PMID:
20667780
21.

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

Hagberg CE, Falkevall A, Wang X, Larsson E, Huusko J, Nilsson I, van Meeteren LA, Samen E, Lu L, Vanwildemeersch M, Klar J, Genove G, Pietras K, Stone-Elander S, Claesson-Welsh L, Ylä-Herttuala S, Lindahl P, Eriksson U.

Nature. 2010 Apr 8;464(7290):917-21. doi: 10.1038/nature08945. Epub 2010 Mar 14.

PMID:
20228789
22.

Radiolabelled proteins for positron emission tomography: Pros and cons of labelling methods.

Tolmachev V, Stone-Elander S.

Biochim Biophys Acta. 2010 May;1800(5):487-510. doi: 10.1016/j.bbagen.2010.02.002. Epub 2010 Feb 11. Review.

PMID:
20153401
23.

Synthesis and preclinical evaluation of [(11)C]PAQ as a PET imaging tracer for VEGFR-2.

Samén E, Thorell JO, Lu L, Tegnebratt T, Holmgren L, Stone-Elander S.

Eur J Nucl Med Mol Imaging. 2009 Aug;36(8):1283-95. doi: 10.1007/s00259-009-1111-3. Epub 2009 Mar 14.

PMID:
19288096
24.

On the selection of a tracer for PET imaging of HER2-expressing tumors: direct comparison of a 124I-labeled affibody molecule and trastuzumab in a murine xenograft model.

Orlova A, Wållberg H, Stone-Elander S, Tolmachev V.

J Nucl Med. 2009 Mar;50(3):417-25. doi: 10.2967/jnumed.108.057919. Epub 2009 Feb 17.

25.

Tagging recombinant proteins with a Sel-tag for purification, labeling with electrophilic compounds or radiolabeling with 11C.

Cheng Q, Stone-Elander S, Arnér ES.

Nat Protoc. 2006;1(2):604-13. Epub 2006 Jul 6.

PMID:
17406287
26.

Microwaving in F-18 chemistry: quirks and tweaks.

Stone-Elander S, Elander N, Thorell JO, Fredriksson A.

Ernst Schering Res Found Workshop. 2007;(62):243-69. Review.

PMID:
17172158
27.

The tyrosine kinase inhibitor PD153035: implication of labeling position on radiometabolites formed in vitro.

Samén E, Thorell JO, Fredriksson A, Stone-Elander S.

Nucl Med Biol. 2006 Nov;33(8):1005-11.

PMID:
17127174
28.

Selenolthiol and dithiol C-terminal tetrapeptide motifs for one-step purification and labeling of recombinant proteins produced in E. coli.

Cheng Q, Johansson L, Thorell JO, Fredriksson A, Samén E, Stone-Elander S, Arnér ES.

Chembiochem. 2006 Dec;7(12):1976-81.

PMID:
17031888
29.

Exploiting the 21st amino acid-purifying and labeling proteins by selenolate targeting.

Johansson L, Chen C, Thorell JO, Fredriksson A, Stone-Elander S, Gafvelin G, Arnér ES.

Nat Methods. 2004 Oct;1(1):61-6. Epub 2004 Sep 29.

PMID:
15782154
30.

Requirements for clinical PET: clarification of the situation in Sweden.

Jacobsson H, Larsson SA, Stone-Elander S.

Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):927. Epub 2004 Mar 18. No abstract available.

PMID:
15034679
31.

A re-entrant cavity for microwave-enhanced chemistry.

Kalhori S, Elander N, Svennebrink J, Stone-Elander S.

J Microw Power Electromagn Energy. 2003;38(2):125-35.

PMID:
15007866
32.

PET screening of anticancer drugs. A faster route to drug/target evaluations in vivo.

Fredriksson A, Stone-Elander S.

Methods Mol Med. 2003;85:279-94. Review. No abstract available.

PMID:
12710215
33.

Residual differences in language processing in compensated dyslexics revealed in simple word reading tasks.

Ingvar M, af Trampe P, Greitz T, Eriksson L, Stone-Elander S, von Euler C.

Brain Lang. 2002 Nov;83(2):249-67.

PMID:
12387797
34.

Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study.

Gulyás B, Vas A, Halldin C, Sóvágó J, Sandell J, Olsson H, Fredriksson A, Stone-Elander S, Farde L.

Nucl Med Biol. 2002 Oct;29(7):753-9.

PMID:
12381455
35.

In vivo biodistribution and pharmacokinetics of (18)F-labeled human C-peptide: evaluation in monkeys using positron emission tomography.

Fredriksson A, Ekberg K, Ingvar M, Johansson BL, Wahren J, Stone-Elander S.

Life Sci. 2002 Aug 9;71(12):1361-70.

PMID:
12127157
36.

Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients.

Blomqvist G, Alvarsson M, Grill V, Von Heijne G, Ingvar M, Thorell JO, Stone-Elander S, Widén L, Ekberg K.

Am J Physiol Endocrinol Metab. 2002 Jul;283(1):E20-8.

37.

UV monitoring of microwave-heated reactions--a feasibility study.

Getvoldsen GS, Elander N, Stone-Elander SA.

Chemistry. 2002 May 17;8(10):2255-60.

PMID:
12012409
38.

[Don't let misunderstandings about PET kill the interest in a valuable technique].

Jacobsson H, Larsson SA, Stone-Elander S.

Lakartidningen. 2000 Jun 28;97(26-27):3210. Swedish. No abstract available.

PMID:
10925583
39.

Pain-related cerebral activation is altered by a distracting cognitive task.

Petrovic P, Petersson KM, Ghatan PH, Stone-Elander S, Ingvar M.

Pain. 2000 Mar;85(1-2):19-30.

PMID:
10692599
40.

A PET activation study of dynamic mechanical allodynia in patients with mononeuropathy.

Petrovic P, Ingvar M, Stone-Elander S, Petersson KM, Hansson P.

Pain. 1999 Dec;83(3):459-70.

PMID:
10568854
41.

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

Fredriksson A, Johnström P, Thorell JO, von Heijne G, Hassan M, Eksborg S, Kogner P, Borgström P, Ingvar M, Stone-Elander S.

Life Sci. 1999;65(2):165-74.

PMID:
10416822
42.

Anticipatory coping of pain expressed in the human anterior cingulate cortex: a positron emission tomography study.

Hsieh JC, Stone-Elander S, Ingvar M.

Neurosci Lett. 1999 Feb 26;262(1):61-4.

PMID:
10076873
43.

The effect of hyperglycaemia on regional cerebral glucose oxidation in humans studied with [1-11C]-D-glucose.

Blomqvist G, Grill V, Ingvar M, Widén L, Stone-Elander S.

Acta Physiol Scand. 1998 Aug;163(4):403-15.

PMID:
9789584
44.

The illiterate brain. Learning to read and write during childhood influences the functional organization of the adult brain.

Castro-Caldas A, Petersson KM, Reis A, Stone-Elander S, Ingvar M.

Brain. 1998 Jun;121 ( Pt 6):1053-63.

PMID:
9648541
45.

Cerebral and cerebellar activation in correlation to the action-induced dystonia in writer's cramp.

Odergren T, Stone-Elander S, Ingvar M.

Mov Disord. 1998 May;13(3):497-508.

PMID:
9613744
46.

Alcohol activates the cerebral reward system in man.

Ingvar M, Ghatan PH, Wirsén-Meurling A, Risberg J, Von Heijne G, Stone-Elander S, Ingvar DH.

J Stud Alcohol. 1998 May;59(3):258-69.

PMID:
9598706
47.

Accumulation of FDG in axillary sweat glands in hyperhidrosis: a pitfall in whole-body PET examination.

Jacobsson H, Celsing F, Ingvar M, Stone-Elander S, Larsson SA.

Eur Radiol. 1998;8(3):482-3.

PMID:
9510592
48.

Cerebral effects of nicotine during cognition in smokers and non-smokers.

Ghatan PH, Ingvar M, Eriksson L, Stone-Elander S, Serrander M, Ekberg K, Wahren J.

Psychopharmacology (Berl). 1998 Mar;136(2):179-89.

PMID:
9551775
49.

Coexistence of attention-based facilitation and inhibition in the human cortex.

Ghatan PH, Hsieh JC, Petersson KM, Stone-Elander S, Ingvar M.

Neuroimage. 1998 Jan;7(1):23-9.

PMID:
9500831
50.

Brief episodes of ventricular fibrillation do not influence postischemic cerebral perfusion assessed by positron emission tomography.

Runsiö M, Brodin LA, Eriksson L, Rosenqvist M, Samuelsson S, Stone-Elander S, Owall A, Ingvar M.

Crit Care Med. 1997 Nov;25(11):1827-30.

PMID:
9366765

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