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Items: 1 to 50 of 296

1.

Chronic Activation of LXR Sensitizes Mice to High Cholesterol Diet Induced Gut Toxicity.

Garbacz WG, Uppal H, Yan J, Xu M, Ren S, Stolz DB, Huang M, Xie W.

Mol Pharmacol. 2018 Jul 25. pii: mol.118.112672. doi: 10.1124/mol.118.112672. [Epub ahead of print]

2.

Hierarchically aligned fibrous hydrogel films through microfluidic self-assembly of graphene and polysaccharides.

Patel A, Xue Y, Hartley R, Sant V, Eles JR, Cui XT, Stolz DB, Sant S.

Biotechnol Bioeng. 2018 Jul 16. doi: 10.1002/bit.26801. [Epub ahead of print]

PMID:
30011077
3.

Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation.

Liu A, Li S, Donnenberg V, Fu J, Gollin SM, Ma H, Lu C, Stolz DB, Mapara MY, Monaghan SA, Lentzsch S.

Haematologica. 2018 Jun 28. pii: haematol.2018.188227. doi: 10.3324/haematol.2018.188227. [Epub ahead of print]

4.

Apical Cell-Cell Adhesions Reconcile Symmetry and Asymmetry in Zebrafish Neurulation.

Guo C, Zou J, Wen Y, Fang W, Stolz DB, Sun M, Wei X.

iScience. 2018 May 25;3:63-85. doi: 10.1016/j.isci.2018.04.007.

5.

Heme Oxygenase-2 Localizes to Mitochondria and Regulates Hypoxic Responses in Hepatocytes.

Waltz PK, Kautza B, Luciano J, Dyer M, Stolz DB, Loughran P, Neal MD, Sperry JL, Rosengart MR, Zuckerbraun BS.

Oxid Med Cell Longev. 2018 Apr 12;2018:2021645. doi: 10.1155/2018/2021645. eCollection 2018.

6.

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms.

Mukherjee A, Hidvegi T, Araya P, Ewing M, Stolz DB, Perlmutter DH.

Cell Death Differ. 2018 May 23. doi: 10.1038/s41418-018-0130-7. [Epub ahead of print]

PMID:
29795336
7.

Conditional depletion of GSK3b protects oligodendrocytes from apoptosis and lessens demyelination in the acute cuprizone model.

Xing B, Brink LE, Maers K, Sullivan ML, Bodnar RJ, Stolz DB, Cambi F.

Glia. 2018 May 15. doi: 10.1002/glia.23453. [Epub ahead of print]

PMID:
29761559
8.

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ.

Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13.

9.

PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors.

Chen D, Tong J, Yang L, Wei L, Stolz DB, Yu J, Zhang J, Zhang L.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3930-3935. doi: 10.1073/pnas.1717190115. Epub 2018 Mar 26.

10.

A Model of Dormant-Emergent Metastatic Breast Cancer Progression Enabling Exploration of Biomarker Signatures.

Clark AM, Kumar MP, Wheeler SE, Young CL, Venkataramanan R, Stolz DB, Griffith LG, Lauffenburger DA, Wells A.

Mol Cell Proteomics. 2018 Apr;17(4):619-630. doi: 10.1074/mcp.RA117.000370. Epub 2018 Jan 20.

PMID:
29353230
11.

Liver 'organ on a chip'.

Beckwitt CH, Clark AM, Wheeler S, Taylor DL, Stolz DB, Griffith L, Wells A.

Exp Cell Res. 2018 Feb 1;363(1):15-25. doi: 10.1016/j.yexcr.2017.12.023. Epub 2017 Dec 29. Review.

PMID:
29291400
12.

Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.

Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR.

Mol Biol Cell. 2018 Feb 15;29(4):499-509. doi: 10.1091/mbc.E17-08-0529. Epub 2017 Dec 13.

13.

Interferon regulatory factor 1 priming of tumour-derived exosomes enhances the antitumour immune response.

Yang MQ, Du Q, Varley PR, Goswami J, Liang Z, Wang R, Li H, Stolz DB, Geller DA.

Br J Cancer. 2018 Jan;118(1):62-71. doi: 10.1038/bjc.2017.389. Epub 2017 Nov 7.

PMID:
29112686
14.

Interferon regulatory factor 1-Rab27a regulated extracellular vesicles promote liver ischemia/reperfusion injury.

Yang MQ, Du Q, Goswami J, Varley PR, Chen B, Wang RH, Morelli AE, Stolz DB, Billiar TR, Li J, Geller DA.

Hepatology. 2018 Mar;67(3):1056-1070. doi: 10.1002/hep.29605. Epub 2018 Jan 24.

PMID:
29059701
15.

Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis.

Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP.

Hepatology. 2018 Jun;67(6):2320-2337. doi: 10.1002/hep.29585. Epub 2018 Apr 19.

PMID:
29023813
16.

Selective knockout of astrocytic Na+ /H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke.

Begum G, Song S, Wang S, Zhao H, Bhuiyan MIH, Li E, Nepomuceno R, Ye Q, Sun M, Calderon MJ, Stolz DB, St Croix C, Watkins SC, Chen Y, He P, Shull GE, Sun D.

Glia. 2018 Jan;66(1):126-144. doi: 10.1002/glia.23232. Epub 2017 Sep 19.

PMID:
28925083
17.

Graft-infiltrating PD-L1hi cross-dressed dendritic cells regulate antidonor T cell responses in mouse liver transplant tolerance.

Ono Y, Perez-Gutierrez A, Nakao T, Dai H, Camirand G, Yoshida O, Yokota S, Stolz DB, Ross MA, Morelli AE, Geller DA, Thomson AW.

Hepatology. 2018 Apr;67(4):1499-1515. doi: 10.1002/hep.29529. Epub 2018 Feb 18.

PMID:
28921638
18.

Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release.

Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, Wang X, Gable MJ, Kretz ES, Di Benedetto G, Lezon TR, Ferrando LM, Larkin TM, Sullivan M, Yablonska S, Wang J, Minnigh MB, Guillaumet G, Suzenet F, Richardson RM, Poloyac SM, Stolz DB, Jockers R, Witt-Enderby PA, Carlisle DL, Vilardaga JP, Friedlander RM.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7997-E8006. doi: 10.1073/pnas.1705768114. Epub 2017 Sep 5.

19.

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1.

Buijs N, Oosterink JE, Jessup M, Schierbeek H, Stolz DB, Houdijk AP, Geller DA, van Leeuwen PA.

Angiogenesis. 2017 Nov;20(4):557-565. doi: 10.1007/s10456-017-9567-4. Epub 2017 Jul 24.

20.

Selective inhibition of small-diameter axons using infrared light.

Lothet EH, Shaw KM, Lu H, Zhuo J, Wang YT, Gu S, Stolz DB, Jansen ED, Horn CC, Chiel HJ, Jenkins MW.

Sci Rep. 2017 Jun 12;7(1):3275. doi: 10.1038/s41598-017-03374-9.

21.

βIII Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons.

Efimova N, Korobova F, Stankewich MC, Moberly AH, Stolz DB, Wang J, Kashina A, Ma M, Svitkina T.

J Neurosci. 2017 Jul 5;37(27):6442-6459. doi: 10.1523/JNEUROSCI.3520-16.2017. Epub 2017 Jun 2.

22.

The Role and Mechanism of Erythrocyte Invasion by Francisella tularensis.

Schmitt DM, Barnes R, Rogerson T, Haught A, Mazzella LK, Ford M, Gilson T, Birch JW, Sjöstedt A, Reed DS, Franks JM, Stolz DB, Denvir J, Fan J, Rekulapally S, Primerano DA, Horzempa J.

Front Cell Infect Microbiol. 2017 May 9;7:173. doi: 10.3389/fcimb.2017.00173. eCollection 2017.

23.

A carboxyl ester lipase (CEL) mutant causes chronic pancreatitis by forming intracellular aggregates that activate apoptosis.

Xiao X, Jones G, Sevilla WA, Stolz DB, Magee KE, Haughney M, Mukherjee A, Wang Y, Lowe ME.

J Biol Chem. 2017 May 12;292(19):7744. doi: 10.1074/jbc.A116.734384. No abstract available.

24.

Correlative Fluorescence and Electron Microscopy in 3D-Scanning Electron Microscope Perspective.

Franks J, Wallace CT, Shibata M, Suga M, Erdman N, Stolz DB, Watkins SC.

Curr Protoc Cytom. 2017 Apr 3;80:12.45.1-12.45.15. doi: 10.1002/cpcy.18.

PMID:
28369763
25.

A Challenging Case of Severe Infantile Cholestasis in Alpha-1 Antitrypsin Deficiency.

Khan Z, Venkat VL, Soltys KA, Stolz DB, Ranganathan S.

Pediatr Dev Pathol. 2017 Mar-Apr;20(2):176-181. doi: 10.1177/1093526616686259. Epub 2017 Jan 25.

26.

Quantitative Analysis of Cellular Senescence in Culture and In Vivo.

Zhao J, Fuhrmann-Stroissnigg H, Gurkar AU, Flores RR, Dorronsoro A, Stolz DB, St Croix CM, Niedernhofer LJ, Robbins PD.

Curr Protoc Cytom. 2017 Jan 5;79:9.51.1-9.51.25. doi: 10.1002/cpcy.16.

PMID:
28055114
27.

Host conditioning and rejection monitoring in hepatocyte transplantation in humans.

Soltys KA, Setoyama K, Tafaleng EN, Soto Gutiérrez A, Fong J, Fukumitsu K, Nishikawa T, Nagaya M, Sada R, Haberman K, Gramignoli R, Dorko K, Tahan V, Dreyzin A, Baskin K, Crowley JJ, Quader MA, Deutsch M, Ashokkumar C, Shneider BL, Squires RH, Ranganathan S, Reyes-Mugica M, Dobrowolski SF, Mazariegos G, Elango R, Stolz DB, Strom SC, Vockley G, Roy-Chowdhury J, Cascalho M, Guha C, Sindhi R, Platt JL, Fox IJ.

J Hepatol. 2017 May;66(5):987-1000. doi: 10.1016/j.jhep.2016.12.017. Epub 2016 Dec 24.

28.

Skin-Resident Effector Memory CD8+CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis.

Li G, Larregina AT, Domsic RT, Stolz DB, Medsger TA Jr, Lafyatis R, Fuschiotti P.

J Invest Dermatol. 2017 May;137(5):1042-1050. doi: 10.1016/j.jid.2016.11.037. Epub 2016 Dec 22.

29.

Bile Duct Ligation Induces ATZ Globule Clearance in a Mouse Model of α-1 Antitrypsin Deficiency.

Khan Z, Yokota S, Ono Y, Bell AW, Oertel M, Stolz DB, Michalopoulos GK.

Gene Expr. 2017 Feb 10;17(2):115-127. doi: 10.3727/105221616X692991. Epub 2016 Aug 18.

30.

A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.

Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A.

Lab Chip. 2016 Dec 20;17(1):156-168.

31.

Aspirin increases mitochondrial fatty acid oxidation.

Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES.

Biochem Biophys Res Commun. 2017 Jan 8;482(2):346-351. doi: 10.1016/j.bbrc.2016.11.066. Epub 2016 Nov 14.

32.

A Carboxyl Ester Lipase (CEL) Mutant Causes Chronic Pancreatitis by Forming Intracellular Aggregates That Activate Apoptosis.

Xiao X, Jones G, Sevilla WA, Stolz DB, Magee KE, Haughney M, Mukherjee A, Wang Y, Lowe ME.

J Biol Chem. 2016 Oct 28;291(44):23224-23236. Epub 2016 Sep 20. Erratum in: J Biol Chem. 2017 May 12;292(19):7744.

33.

Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.

Long TJ, Cosgrove PA, Dunn RT 2nd, Stolz DB, Hamadeh H, Afshari C, McBride H, Griffith LG.

Drug Metab Dispos. 2016 Dec;44(12):1940-1948. Epub 2016 Sep 12.

34.

Characterization of Endocytic Vesicles Using Magnetic Microbeads Coated with Signaling Ligands.

Li HS, Stolz DB, Romero G.

Traffic. 2016 Oct;17(10):1150. doi: 10.1111/tra.12424. No abstract available.

35.

Tenascin-C Is a Major Component of the Fibrogenic Niche in Kidney Fibrosis.

Fu H, Tian Y, Zhou L, Zhou D, Tan RJ, Stolz DB, Liu Y.

J Am Soc Nephrol. 2017 Mar;28(3):785-801. doi: 10.1681/ASN.2016020165. Epub 2016 Sep 9.

36.

Globin X is a six-coordinate globin that reduces nitrite to nitric oxide in fish red blood cells.

Corti P, Xue J, Tejero J, Wajih N, Sun M, Stolz DB, Tsang M, Kim-Shapiro DB, Gladwin MT.

Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):8538-43. doi: 10.1073/pnas.1522670113. Epub 2016 Jul 12.

37.

Matrix-bound nanovesicles within ECM bioscaffolds.

Huleihel L, Hussey GS, Naranjo JD, Zhang L, Dziki JL, Turner NJ, Stolz DB, Badylak SF.

Sci Adv. 2016 Jun 10;2(6):e1600502. doi: 10.1126/sciadv.1600502. eCollection 2016 Jun.

38.

Donor dendritic cell-derived exosomes promote allograft-targeting immune response.

Liu Q, Rojas-Canales DM, Divito SJ, Shufesky WJ, Stolz DB, Erdos G, Sullivan ML, Gibson GA, Watkins SC, Larregina AT, Morelli AE.

J Clin Invest. 2016 Aug 1;126(8):2805-20. doi: 10.1172/JCI84577. Epub 2016 Jun 27.

39.

IGF-1 and Chondroitinase ABC Augment Nerve Regeneration after Vascularized Composite Limb Allotransplantation.

Kostereva NV, Wang Y, Fletcher DR, Unadkat JV, Schnider JT, Komatsu C, Yang Y, Stolz DB, Davis MR, Plock JA, Gorantla VS.

PLoS One. 2016 Jun 7;11(6):e0156149. doi: 10.1371/journal.pone.0156149. eCollection 2016.

40.

αT-Catenin Is a Constitutive Actin-binding α-Catenin That Directly Couples the Cadherin·Catenin Complex to Actin Filaments.

Wickline ED, Dale IW, Merkel CD, Heier JA, Stolz DB, Kwiatkowski AV.

J Biol Chem. 2016 Jul 22;291(30):15687-99. doi: 10.1074/jbc.M116.735423. Epub 2016 May 26.

41.

The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization.

Treat AC, Wheeler DS, Stolz DB, Tsang M, Friedman PA, Romero G.

PLoS One. 2016 Apr 7;11(4):e0153144. doi: 10.1371/journal.pone.0153144. eCollection 2016.

42.

Cell-Instructive Graphene-Containing Nanocomposites Induce Multinucleated Myotube Formation.

Patel A, Xue Y, Mukundan S, Rohan LC, Sant V, Stolz DB, Sant S.

Ann Biomed Eng. 2016 Jun;44(6):2036-48. doi: 10.1007/s10439-016-1586-6. Epub 2016 Mar 16.

PMID:
26983841
43.

Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine Colitis.

Cunningham KE, Vincent G, Sodhi CP, Novak EA, Ranganathan S, Egan CE, Stolz DB, Rogers MB, Firek B, Morowitz MJ, Gittes GK, Zuckerbraun BS, Hackam DJ, Mollen KP.

J Biol Chem. 2016 May 6;291(19):10184-200. doi: 10.1074/jbc.M115.688812. Epub 2016 Mar 11.

44.

A CHALLENGING CASE OF SEVERE INFANTILE CHOLESTASIS IN ALPHA-1 ANTITRYPSIN DEFICIENCY.

Khan Z, Venkat VL, Soltys KA, Stolz DB, Ranganathan S.

Pediatr Dev Pathol. 2016 Feb 8. [Epub ahead of print]

PMID:
26855337
45.

Functional Immune Anatomy of the Liver-As an Allograft.

Demetris AJ, Bellamy CO, Gandhi CR, Prost S, Nakanuma Y, Stolz DB.

Am J Transplant. 2016 Jun;16(6):1653-80. doi: 10.1111/ajt.13749. Epub 2016 Mar 21. Review.

46.

Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine.

Wheeler DS, Underhill SM, Stolz DB, Murdoch GH, Thiels E, Romero G, Amara SG.

Proc Natl Acad Sci U S A. 2015 Dec 22;112(51):E7138-47. doi: 10.1073/pnas.1511670112. Epub 2015 Nov 9.

47.

Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism.

Dheer R, Patterson J, Dudash M, Stachler EN, Bibby KJ, Stolz DB, Shiva S, Wang Z, Hazen SL, Barchowsky A, Stolz JF.

Toxicol Appl Pharmacol. 2015 Dec 15;289(3):397-408. doi: 10.1016/j.taap.2015.10.020. Epub 2015 Oct 31.

48.

Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.

Hidvegi T, Stolz DB, Alcorn JF, Yousem SA, Wang J, Leme AS, Houghton AM, Hale P, Ewing M, Cai H, Garchar EA, Pastore N, Annunziata P, Kaminski N, Pilewski J, Shapiro SD, Pak SC, Silverman GA, Brunetti-Pierri N, Perlmutter DH.

J Biol Chem. 2015 Dec 11;290(50):29742-57. doi: 10.1074/jbc.M115.691253. Epub 2015 Oct 22.

49.

Mice with Hepatic Loss of the Desmosomal Protein γ-Catenin Are Prone to Cholestatic Injury and Chemical Carcinogenesis.

Zhou L, Pradhan-Sundd T, Poddar M, Singh S, Kikuchi A, Stolz DB, Shou W, Li Z, Nejak-Bowen KN, Monga SP.

Am J Pathol. 2015 Dec;185(12):3274-89. doi: 10.1016/j.ajpath.2015.08.019. Epub 2015 Oct 17.

50.

Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs.

Phinney DG, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix CM, Stolz DB, Watkins SC, Di YP, Leikauf GD, Kolls J, Riches DW, Deiuliis G, Kaminski N, Boregowda SV, McKenna DH, Ortiz LA.

Nat Commun. 2015 Oct 7;6:8472. doi: 10.1038/ncomms9472.

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