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Items: 1 to 50 of 291

1.

Efficacy and safety of inhaled alpha-1-antitrypsin in patients with severe alpha-1-antitrypsin deficiency and frequent exacerbations of Chronic Obstructive Pulmonary Disease.

Stolk J, Tov N, Chapman KR, Fernandez P, MacNee W, Hopkinson NS, Piitulainen E, Seersholm N, Vogelmeier CF, Bals R, McElvaney G, Stockley RA.

Eur Respir J. 2019 Aug 29. pii: 1900673. doi: 10.1183/13993003.00673-2019. [Epub ahead of print]

PMID:
31467115
2.

Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation.

Hamesch K, Mandorfer M, Pereira VM, Moeller LS, Pons M, Dolman GE, Reichert MC, Schneider CV, Woditsch V, Voss J, Lindhauer C, Fromme M, Spivak I, Guldiken N, Zhou B, Arslanow A, Schaefer B, Zoller H, Aigner E, Reiberger T, Wetzel M, Siegmund B, Simões C, Gaspar R, Maia L, Costa D, Bento-Miranda M, van Helden J, Yagmur E, Bzdok D, Stolk J, Gleiber W, Knipel V, Windisch W, Mahadeva R, Bals R, Koczulla R, Barrecheguren M, Miravitlles M, Janciauskiene S, Stickel F, Lammert F, Liberal R, Genesca J, Griffiths WJ, Trauner M, Krag A, Trautwein C, Strnad P; European Alpha1-Liver Study Group.

Gastroenterology. 2019 Sep;157(3):705-719.e18. doi: 10.1053/j.gastro.2019.05.013. Epub 2019 May 20.

PMID:
31121167
3.

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation.

Ng-Blichfeldt JP, de Jong T, Kortekaas RK, Wu X, Lindner M, Guryev V, Hiemstra PS, Stolk J, Königshoff M, Gosens R.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L14-L28. doi: 10.1152/ajplung.00400.2018. Epub 2019 Apr 10.

PMID:
30969812
4.

Blood monocyte profiles in COPD patients with PiMM and PiZZ α1-antitrypsin.

Stolk J, Aggarwal N, Hochnadel I, Wrenger S, Martinez-Delgado B, Welte T, Yevsa T, Janciauskiene S.

Respir Med. 2019 Mar;148:60-62. doi: 10.1016/j.rmed.2019.02.001. Epub 2019 Feb 6.

PMID:
30827477
5.

Regional lung densities in alpha-1 antitrypsin deficiency compared to predicted values.

Stoel BC, Stolk J, Bakker ME, Parr DG.

Respir Res. 2019 Feb 28;20(1):45. doi: 10.1186/s12931-019-1012-3.

6.

Pulmonary Vascular Morphology Associated With Gas Exchange in Systemic Sclerosis Without Lung Fibrosis.

Zhai Z, Staring M, Ninaber MK, Vries-Bouwstra JK, Schouffoer AA, Kroft LJ, Stolk J, Stoel BC.

J Thorac Imaging. 2019 Feb 25. doi: 10.1097/RTI.0000000000000395. [Epub ahead of print]

PMID:
30817504
7.

The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency.

Miravitlles M, Chorostowska-Wynimko J, Ferrarotti I, McElvaney NG, O'Hara K, Stolk J, Stockley RA, Turner A, Wilkens M, Greulich T; EARCO Clinical Research Collaboration; Members of the EARCO Clinical Research Collaboration.

Eur Respir J. 2019 Feb 14;53(2). pii: 1900138. doi: 10.1183/13993003.00138-2019. Print 2019 Feb. No abstract available.

PMID:
30765486
8.

Lectin Complement Pathway in Emphysema.

Serban KA, Mikosz A, Strange C, Janciauskiene SM, Stolk J, Jonigk D, Sandhaus RA, Petrache I.

Am J Respir Crit Care Med. 2019 Mar 1;199(5):659-661. doi: 10.1164/rccm.201807-1380LE. No abstract available.

PMID:
30557515
9.

Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation.

Ng-Blichfeldt JP, Schrik A, Kortekaas RK, Noordhoek JA, Heijink IH, Hiemstra PS, Stolk J, Königshoff M, Gosens R.

EBioMedicine. 2018 Oct;36:461-474. doi: 10.1016/j.ebiom.2018.09.002. Epub 2018 Sep 17.

10.

Ticking off diagnoses of abdominal pain: early neuroborreliosis with radiculopathy.

Stolk JM, van Nieuwkoop C, van der Voorn MPJA, van Erp S, van Burgel ND.

Neth J Med. 2018 Sep;76(7):336-338.

11.

Mesenchymal stromal cells: a novel therapy for the treatment of chronic obstructive pulmonary disease?

Broekman W, Khedoe PPSJ, Schepers K, Roelofs H, Stolk J, Hiemstra PS.

Thorax. 2018 Jun;73(6):565-574. doi: 10.1136/thoraxjnl-2017-210672. Epub 2018 Apr 13. Review.

12.

Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients.

Turner AM, Stolk J, Bals R, Lickliter JD, Hamilton J, Christianson DR, Given BD, Burdon JG, Loomba R, Stoller JK, Teckman JH.

J Hepatol. 2018 Aug;69(2):378-384. doi: 10.1016/j.jhep.2018.03.012. Epub 2018 Mar 21.

PMID:
29572094
13.

Treatment Effect of Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension Quantified by Automatic Comparative Imaging in Computed Tomography Pulmonary Angiography.

Zhai Z, Ota H, Staring M, Stolk J, Sugimura K, Takase K, Stoel BC.

Invest Radiol. 2018 May;53(5):286-292. doi: 10.1097/RLI.0000000000000441.

PMID:
29278545
14.

European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency.

Miravitlles M, Dirksen A, Ferrarotti I, Koblizek V, Lange P, Mahadeva R, McElvaney NG, Parr D, Piitulainen E, Roche N, Stolk J, Thabut G, Turner A, Vogelmeier C, Stockley RA.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700610. doi: 10.1183/13993003.00610-2017. Print 2017 Nov. Review.

15.

Impact of Stopping Tumor Necrosis Factor Inhibitors on Rheumatoid Arthritis Patients' Burden of Disease.

Ghiti Moghadam M, Ten Klooster PM, Vonkeman HE, Kneepkens EL, Klaasen R, Stolk JN, Tchetverikov I, Vreugdenhil SA, van Woerkom JM, Goekoop-Ruiterman YPM, Landewé RBM, van Riel PLCM, van de Laar MAFJ, Jansen TL; Dutch National POET Collaboration.

Arthritis Care Res (Hoboken). 2018 Apr;70(4):516-524. doi: 10.1002/acr.23315.

16.

Lung Density and Pulmonary Artery Diameter are Predictors of Pulmonary Hypertension in Systemic Sclerosis.

Bakker ME, Ninaber MK, Stolk J, Kroft LJM, Schouffoer AA, de Vries Bouwstra JK, van Wijngaarden SE, Stoel BC.

J Thorac Imaging. 2017 Nov;32(6):391-397. doi: 10.1097/RTI.0000000000000279.

PMID:
28549020
17.

Patterns and characterization of COPD exacerbations using real-time data collection.

Ejiofor SI, Stolk J, Fernandez P, Stockley RA.

Int J Chron Obstruct Pulmon Dis. 2017 Jan 25;12:427-434. doi: 10.2147/COPD.S126158. eCollection 2017.

18.

Identification of Novel Short C-Terminal Transcripts of Human SERPINA1 Gene.

Matamala N, Aggarwal N, Iadarola P, Fumagalli M, Gomez-Mariano G, Lara B, Martinez MT, Cuesta I, Stolk J, Janciauskiene S, Martinez-Delgado B.

PLoS One. 2017 Jan 20;12(1):e0170533. doi: 10.1371/journal.pone.0170533. eCollection 2017.

19.

[To reimburse or not? Evaluating expensive drugs differently].

Stolk J.

Ned Tijdschr Geneeskd. 2016;160:D1022. Dutch.

PMID:
27879186
20.

Advances in Identifying Urine/Serum Biomarkers in Alpha-1 Antitrypsin Deficiency for More Personalized Future Treatment Strategies.

Ferrarotti I, Corsico AG, Stolk J, Ottaviani S, Fumagalli M, Janciauskiene S, Iadarola P.

COPD. 2017 Feb;14(1):56-65. doi: 10.1080/15412555.2016.1241760. Epub 2016 Nov 9. Review.

PMID:
27827549
21.

Functional characterisation of bone marrow-derived mesenchymal stromal cells from COPD patients.

Broekman W, Roelofs H, Zarcone MC, Taube C, Stolk J, Hiemstra PS.

ERJ Open Res. 2016 Jun 28;2(2). pii: 00045-2015. eCollection 2016 Apr.

22.

1H NMR To Explore the Metabolome of Exhaled Breath Condensate in α1-Antitrypsin Deficient Patients: A Pilot Study.

Airoldi C, Ciaramelli C, Fumagalli M, Bussei R, Mazzoni V, Viglio S, Iadarola P, Stolk J.

J Proteome Res. 2016 Dec 2;15(12):4569-4578. Epub 2016 Oct 5.

PMID:
27646345
23.

Clinical development of MUSE cell treatment: The challenges.

Stolk J.

Cell Cycle. 2016 Dec;15(23):3165-3166. Epub 2016 Aug 30. No abstract available.

24.

Effectiveness of Tumor Necrosis Factor Inhibitors in Combination with Various csDMARD in the Treatment of Rheumatoid Arthritis: Data from the DREAM Registry.

Manders SH, Kievit W, Jansen TL, Stolk JN, Visser H, Schilder AM, Vonkeman HE, Adang E, van de Laar MA, van Riel PL.

J Rheumatol. 2016 Oct;43(10):1787-1794. Epub 2016 Aug 1.

PMID:
27481900
25.

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation.

Verheul MK, van Erp SJ, van der Woude D, Levarht EW, Mallat MJ, Verspaget HW, Stolk J, Toes RE, van der Meulen-de Jong AE, Hiemstra PS, van Kooten C, Trouw LA.

Ann Rheum Dis. 2016 Aug;75(8):1575-6. doi: 10.1136/annrheumdis-2016-209248. Epub 2016 Apr 29. No abstract available.

PMID:
27130909
26.

Alpha-1 Antitrypsin Regulates Transcriptional Levels of Serine Proteases in Blood Mononuclear Cells.

Aggarwal N, Koepke J, Matamala N, Martinez-Delgado B, Martinez MT, Golpon H, Stolk J, Janciauskiene S, Koczulla R.

Am J Respir Crit Care Med. 2016 May 1;193(9):1065-7. doi: 10.1164/rccm.201510-2062LE. No abstract available.

PMID:
27128707
27.

[Legionella pneumonia after the use of CPAP equipment].

Stolk JM, Russcher A, van Elzakker EP, Schippers EF.

Ned Tijdschr Geneeskd. 2016;160:A9855. Review. Dutch.

PMID:
27096478
28.

A phase I study for intravenous autologous mesenchymal stromal cell administration to patients with severe emphysema.

Stolk J, Broekman W, Mauad T, Zwaginga JJ, Roelofs H, Fibbe WE, Oostendorp J, Bajema I, Versteegh MI, Taube C, Hiemstra PS.

QJM. 2016 May;109(5):331-6. doi: 10.1093/qjmed/hcw001. Epub 2016 Jan 27.

29.

Pulmonary Fissure Detection in CT Images Using a Derivative of Stick Filter.

Xiao C, Stoel BC, Bakker ME, Peng Y, Stolk J, Staring M.

IEEE Trans Med Imaging. 2016 Jun;35(6):1488-500. doi: 10.1109/TMI.2016.2517680. Epub 2016 Jan 13.

PMID:
26766371
30.

TNF-α and IL-1β-activated human mesenchymal stromal cells increase airway epithelial wound healing in vitro via activation of the epidermal growth factor receptor.

Broekman W, Amatngalim GD, de Mooij-Eijk Y, Oostendorp J, Roelofs H, Taube C, Stolk J, Hiemstra PS.

Respir Res. 2016 Jan 11;17:3. doi: 10.1186/s12931-015-0316-1.

31.

Impact of pulmonary fibrosis and elevated pulmonary pressures on right ventricular function in patients with systemic sclerosis.

Yiu KH, Ninaber MK, Kroft LJ, Schouffoer AA, Stolk J, Scherer HU, Meijs J, de Vries-Bouwstra J, Tse HF, Delgado V, Bax JJ, Huizinga TW, Marsan NA.

Rheumatology (Oxford). 2016 Mar;55(3):504-12. doi: 10.1093/rheumatology/kev342. Epub 2015 Oct 15.

PMID:
26472568
32.

Relationship between Change in Lung Density and Long-Term Progression of Lung Function.

Stolk J, Stockley RA, Piitulainen E, Stoel BC.

Am J Respir Crit Care Med. 2015 Jul 1;192(1):114-6. doi: 10.1164/rccm.201502-0370LE. No abstract available.

PMID:
26131993
33.

Association of Lung Inflammatory Cells with Small Airways Function and Exhaled Breath Markers in Smokers - Is There a Specific Role for Mast Cells?

Nussbaumer-Ochsner Y, Stolk J, Ferraz da Silva LF, van Schadewijk A, de Jeu RC, Prins FA, Mauad T, Rabe KF, Hiemstra PS.

PLoS One. 2015 Jun 12;10(6):e0129426. doi: 10.1371/journal.pone.0129426. eCollection 2015.

34.

Conductivity in Exhaled Breath Condensate from Subjects with Emphysema and Type ZZ alpha-1-Antitrypsin Deficiency.

Stolk J, Fumagalli M, Viglio S, Iadarola P.

COPD. 2015 May;12 Suppl 1:32-5. doi: 10.3109/15412555.2015.1021910.

PMID:
25938289
35.

Lung structure and function relation in systemic sclerosis: application of lung densitometry.

Ninaber MK, Stolk J, Smit J, Le Roy EJ, Kroft LJ, Bakker ME, de Vries Bouwstra JK, Schouffoer AA, Staring M, Stoel BC.

Eur J Radiol. 2015 May;84(5):975-9. doi: 10.1016/j.ejrad.2015.01.012. Epub 2015 Jan 22.

PMID:
25650330
36.

Effectiveness of TNF inhibitor treatment with various methotrexate doses in patients with rheumatoid arthritis: results from clinical practice.

Manders SH, Kievit W, Adang E, Jansen TJ, Stolk JN, Visser H, Schilder AM, Vonkeman HE, van de Laar MA, van Riel PL.

Ann Rheum Dis. 2015 Mar;74(3):e24. doi: 10.1136/annrheumdis-2014-207005. Epub 2014 Dec 5. No abstract available.

PMID:
25480886
37.

Function of monocytes and monocyte-derived macrophages in α1-antitrypsin deficiency.

Van't Wout EF, van Schadewijk A, Lomas DA, Stolk J, Marciniak SJ, Hiemstra PS.

Eur Respir J. 2015 Feb;45(2):365-76. doi: 10.1183/09031936.00046114. Epub 2014 Oct 16.

38.

Detection of pulmonary vasculopathy by novel analysis of oxygen uptake in patients with systemic sclerosis: association with pulmonary arterial pressures.

Ninaber MK, Hamersma WB, Schouffoer AA, Kovacs G, Olschewski H, Holman ER, Ajmone Marsan N, Stolk J.

Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-60-7. Epub 2014 Jul 17.

PMID:
25068203
39.

The global peripheral chemoreflex drive in patients with systemic sclerosis: a rebreathing and exercise study.

Ninaber MK, Hamersma WB, Schouffoer AA, van 't Wout EF, Stolk J.

QJM. 2015 Jan;108(1):33-8. doi: 10.1093/qjmed/hcu150. Epub 2014 Jul 13.

PMID:
25024353
40.

Increased respiratory drive relates to severity of dyspnea in systemic sclerosis.

Ninaber MK, Hamersma WB, Schuerwegh AJ, Stolk J.

BMC Pulm Med. 2014 Apr 4;14:57. doi: 10.1186/1471-2466-14-57.

41.

Towards local progression estimation of pulmonary emphysema using CT.

Staring M, Bakker ME, Stolk J, Shamonin DP, Reiber JH, Stoel BC.

Med Phys. 2014 Feb;41(2):021905. doi: 10.1118/1.4851535.

PMID:
24506626
42.

Respiratory Proteomics Today: Are Technological Advances for the Identification of Biomarker Signatures Catching up with Their Promise? A Critical Review of the Literature in the Decade 2004-2013.

Viglio S, Stolk J, Iadarola P, Giuliano S, Luisetti M, Salvini R, Fumagalli M, Bardoni A.

Proteomes. 2014 Jan 22;2(1):18-52. doi: 10.3390/proteomes2010018. Review.

43.

From micellar electrokinetic chromatography to liquid chromatography-mass spectrometry: revisiting the way of analyzing human fluids for the search of desmosines, putative biomarkers of chronic obstructive pulmonary disease.

Viglio S, Stolk J, Luisetti M, Ferrari F, Piccinini P, Iadarola P.

Electrophoresis. 2014 Jan;35(1):109-18. doi: 10.1002/elps.201300159. Epub 2013 Oct 23. Review.

PMID:
24395662
44.

Increased ERK signalling promotes inflammatory signalling in primary airway epithelial cells expressing Z α1-antitrypsin.

van 't Wout EF, Dickens JA, van Schadewijk A, Haq I, Kwok HF, Ordóñez A, Murphy G, Stolk J, Lomas DA, Hiemstra PS, Marciniak SJ.

Hum Mol Genet. 2014 Feb 15;23(4):929-41. doi: 10.1093/hmg/ddt487. Epub 2013 Oct 4.

45.

Alpha-1 antitrypsin deficiency: the European experience.

Stockley RA, Dirksen A, Stolk J.

COPD. 2013 Mar;10 Suppl 1:50-3. doi: 10.3109/15412555.2013.765838. Review.

PMID:
23527820
46.

Profiling the proteome of exhaled breath condensate in healthy smokers and COPD patients by LC-MS/MS.

Fumagalli M, Ferrari F, Luisetti M, Stolk J, Hiemstra PS, Capuano D, Viglio S, Fregonese L, Cerveri I, Corana F, Tinelli C, Iadarola P.

Int J Mol Sci. 2012 Oct 29;13(11):13894-910. doi: 10.3390/ijms131113894.

47.

Micellar electrokinetic chromatography with laser induced detection and liquid chromatography tandem mass-spectrometry-based desmosine assays in urine of patients with Chronic Obstructive Pulmonary Disease: a comparative analysis.

Ferrari F, Fumagalli M, Piccinini P, Stolk J, Luisetti M, Viglio S, Tinelli C, Iadarola P.

J Chromatogr A. 2012 Nov 30;1266:103-9. doi: 10.1016/j.chroma.2012.10.014. Epub 2012 Oct 13.

PMID:
23116803
48.

[A man who could only sleep sitting].

Schimmel RJ, Stolk J, Versteegh MI, Rommes JH.

Ned Tijdschr Geneeskd. 2012;156(34):A4860. Dutch.

PMID:
22914058
49.

Desmosine, a biomarker for COPD: old and in the way.

Luisetti M, Stolk J, Iadarola P.

Eur Respir J. 2012 Apr;39(4):797-8. doi: 10.1183/09031936.00172911. No abstract available.

50.

Randomised controlled trial for emphysema with a selective agonist of the γ-type retinoic acid receptor.

Stolk J, Stockley RA, Stoel BC, Cooper BG, Piitulainen E, Seersholm N, Chapman KR, Burdon JG, Decramer M, Abboud RT, Mannes GP, Wouters EF, Garrett JE, Barros-Tizon JC, Russi EW, Lomas DA, MacNee WA, Rames A.

Eur Respir J. 2012 Aug;40(2):306-12. doi: 10.1183/09031936.00161911. Epub 2012 Jan 26.

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