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Items: 1 to 50 of 53

1.

RORγt-Expressing Tregs Drive the Growth of Colitis-Associated Colorectal Cancer by Controlling IL6 in Dendritic Cells.

Rizzo A, Di Giovangiulio M, Stolfi C, Franzè E, Fehling HJ, Carsetti R, Giorda E, Colantoni A, Ortenzi A, Rugge M, Mescoli C, Monteleone G, Fantini MC.

Cancer Immunol Res. 2018 Jul 10. pii: canimm.0698.2017. doi: 10.1158/2326-6066.CIR-17-0698. [Epub ahead of print]

PMID:
29991500
2.

Transforming Growth Factor-β1/Smad7 in Intestinal Immunity, Inflammation, and Cancer.

Troncone E, Marafini I, Stolfi C, Monteleone G.

Front Immunol. 2018 Jun 20;9:1407. doi: 10.3389/fimmu.2018.01407. eCollection 2018. Review.

3.

STAT3 Interactors as Potential Therapeutic Targets for Cancer Treatment.

Laudisi F, Cherubini F, Monteleone G, Stolfi C.

Int J Mol Sci. 2018 Jun 16;19(6). pii: E1787. doi: 10.3390/ijms19061787. Review.

4.

Metformin inhibits inflammatory signals in the gut by controlling AMPK and p38 MAP kinase activation.

Di Fusco D, Dinallo V, Monteleone I, Laudisi F, Marafini I, Franzè E, Di Grazia A, Dwairi R, Colantoni A, Ortenzi A, Stolfi C, Monteleone G.

Clin Sci (Lond). 2018 Jun 12;132(11):1155-1168. doi: 10.1042/CS20180167. Print 2018 Jun 15.

PMID:
29540537
5.

Interleukin-34 sustains pro-tumorigenic signals in colon cancer tissue.

Franzè E, Dinallo V, Rizzo A, Di Giovangiulio M, Bevivino G, Stolfi C, Caprioli F, Colantoni A, Ortenzi A, Grazia AD, Sica G, Sileri PP, Rossi P, Monteleone G.

Oncotarget. 2017 Dec 15;9(3):3432-3445. doi: 10.18632/oncotarget.23289. eCollection 2018 Jan 9.

6.

Smad7 positively regulates keratinocyte proliferation in psoriasis.

Di Fusco D, Laudisi F, Dinallo V, Monteleone I, Di Grazia A, Marafini I, Troncone E, Colantoni A, Ortenzi A, Stolfi C, Picardo M, Monteleone G.

Br J Dermatol. 2017 Dec;177(6):1633-1643. doi: 10.1111/bjd.15703. Epub 2017 Nov 16.

PMID:
28580633
7.

Smad7 knockdown activates protein kinase RNA-associated eIF2α pathway leading to colon cancer cell death.

De Simone V, Bevivino G, Sedda S, Izzo R, Laudisi F, Dinallo V, Franzè E, Colantoni A, Ortenzi A, Salvatori S, Rossi P, Sica GS, Fantini MC, Stolfi C, Monteleone G.

Cell Death Dis. 2017 Mar 16;8(3):e2681. doi: 10.1038/cddis.2017.103.

8.

BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis.

Sakamoto N, Feng Y, Stolfi C, Kurosu Y, Green M, Lin J, Green ME, Sentani K, Yasui W, McMahon M, Hardiman KM, Spence JR, Horita N, Greenson JK, Kuick R, Cho KR, Fearon ER.

Elife. 2017 Jan 10;6. pii: e20331. doi: 10.7554/eLife.20331.

9.

Detection methods and clinical significance of free peritoneal tumor cells found during colorectal cancer surgery.

Sibio S, Fiorani C, Stolfi C, Divizia A, Pezzuto R, Montagnese F, Bagaglini G, Sammartino P, Sica GS.

World J Gastrointest Surg. 2015 Sep 27;7(9):178-84. doi: 10.4240/wjgs.v7.i9.178.

10.

Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis.

De Simone V, Ronchetti G, Franzè E, Colantoni A, Ortenzi A, Fantini MC, Rizzo A, Sica GS, Sileri P, Rossi P, MacDonald TT, Pallone F, Monteleone G, Stolfi C.

Oncotarget. 2015 Apr 30;6(12):9908-23.

11.

Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer.

Sica GS, Fiorani C, Stolfi C, Monteleone G, Candi E, Amelio I, Catani V, Sibio S, Divizia A, Tema G, Iaculli E, Gaspari AL.

Oncotarget. 2015 May 30;6(15):13402-15.

12.

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.

De Simone V, Franzè E, Ronchetti G, Colantoni A, Fantini MC, Di Fusco D, Sica GS, Sileri P, MacDonald TT, Pallone F, Monteleone G, Stolfi C.

Oncogene. 2015 Jul;34(27):3493-503. doi: 10.1038/onc.2014.286. Epub 2014 Sep 1.

13.

Defective expression of SIRT1 contributes to sustain inflammatory pathways in the gut.

Caruso R, Marafini I, Franzè E, Stolfi C, Zorzi F, Monteleone I, Caprioli F, Colantoni A, Sarra M, Sedda S, Biancone L, Sileri P, Sica GS, MacDonald TT, Pallone F, Monteleone G.

Mucosal Immunol. 2014 Nov;7(6):1467-79. doi: 10.1038/mi.2014.35. Epub 2014 May 21.

PMID:
24850427
14.

A functional role for Smad7 in sustaining colon cancer cell growth and survival.

Stolfi C, De Simone V, Colantoni A, Franzè E, Ribichini E, Fantini MC, Caruso R, Monteleone I, Sica GS, Sileri P, MacDonald TT, Pallone F, Monteleone G.

Cell Death Dis. 2014 Feb 20;5:e1073. doi: 10.1038/cddis.2014.49.

15.

Role of TH17 cytokines in the control of colorectal cancer.

De Simone V, Pallone F, Monteleone G, Stolfi C.

Oncoimmunology. 2013 Dec 1;2(12):e26617. Epub 2013 Oct 22. Review.

16.

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

Rizzo A, De Mare V, Rocchi C, Stolfi C, Colantoni A, Neurath MF, Macdonald TT, Pallone F, Monteleone G, Fantini MC.

Carcinogenesis. 2014 Jul;35(7):1536-46. doi: 10.1093/carcin/bgu027. Epub 2014 Jan 30.

PMID:
24480808
17.

The dual role of Smad7 in the control of cancer growth and metastasis.

Stolfi C, Marafini I, De Simone V, Pallone F, Monteleone G.

Int J Mol Sci. 2013 Dec 5;14(12):23774-90. doi: 10.3390/ijms141223774. Review.

18.

Mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDs) and mesalazine in the chemoprevention of colorectal cancer.

Stolfi C, De Simone V, Pallone F, Monteleone G.

Int J Mol Sci. 2013 Sep 3;14(9):17972-85. doi: 10.3390/ijms140917972. Review.

19.

Lesional accumulation of CD163-expressing cells in the gut of patients with inflammatory bowel disease.

Franzè E, Caruso R, Stolfi C, Sarra M, Cupi ML, Caprioli F, Monteleone I, Zorzi F, De Nitto D, Colantoni A, Biancone L, Pallone F, Monteleone G.

PLoS One. 2013 Jul 26;8(7):e69839. doi: 10.1371/journal.pone.0069839. Print 2013.

20.

High expression of the "A Disintegrin And Metalloprotease" 19 (ADAM19), a sheddase for TNF-α in the mucosa of patients with inflammatory bowel diseases.

Franzè E, Caruso R, Stolfi C, Sarra M, Cupi ML, Ascolani M, Sedda S, Antenucci C, Ruffa A, Caprioli F, MacDonald TT, Pallone F, Monteleone G.

Inflamm Bowel Dis. 2013 Mar;19(3):501-11. doi: 10.1097/MIB.0b013e31828028e8.

PMID:
23429442
21.

Collagen matrix injection combined with flap repair for complex anal fistula.

Sileri P, Boehm G, Franceschilli L, Giorgi F, Perrone F, Stolfi C, Monteleone G, Gaspari AL.

Colorectal Dis. 2012 Dec;14 Suppl 3:24-8. doi: 10.1111/codi.12046.

PMID:
23136821
22.

The dual role of inflammation in colon carcinogenesis.

Monteleone G, Pallone F, Stolfi C.

Int J Mol Sci. 2012;13(9):11071-84. doi: 10.3390/ijms130911071. Epub 2012 Sep 6. Review.

23.

Molecular targets of TRAIL-sensitizing agents in colorectal cancer.

Stolfi C, Pallone F, Monteleone G.

Int J Mol Sci. 2012;13(7):7886-901. doi: 10.3390/ijms13077886. Epub 2012 Jun 25. Review.

24.

Interleukin-21 in cancer immunotherapy: Friend or foe?

Stolfi C, Pallone F, Macdonald TT, Monteleone G.

Oncoimmunology. 2012 May 1;1(3):351-354.

25.

Colorectal cancer chemoprevention by mesalazine and its derivatives.

Stolfi C, Pallone F, Monteleone G.

J Biomed Biotechnol. 2012;2012:980458. doi: 10.1155/2012/980458. Epub 2012 Jun 4. Review.

26.

2-Methoxy-5-amino-N-hydroxybenzamide, a derivative of mesalamine, inhibits colon cancer cell growth through cyclo-oxygenase-2-dependent and -independent mechanisms.

Stolfi C, Franzè E, Monteleone I, Caruso R, Franceschilli L, Sileri P, Sica GS, Gaspari AL, Del Vecchio Blanco G, Pallone F, Monteleone G.

Clin Sci (Lond). 2012 Sep;123(5):295-306. doi: 10.1042/CS20110556.

PMID:
22435743
27.

Smad7 expression in T cells prevents colitis-associated cancer.

Rizzo A, Waldner MJ, Stolfi C, Sarra M, Fina D, Becker C, Neurath MF, Macdonald TT, Pallone F, Monteleone G, Fantini MC.

Cancer Res. 2011 Dec 15;71(24):7423-32. doi: 10.1158/0008-5472.CAN-11-1895. Epub 2011 Oct 25.

28.

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer.

Stolfi C, Rizzo A, Franzè E, Rotondi A, Fantini MC, Sarra M, Caruso R, Monteleone I, Sileri P, Franceschilli L, Caprioli F, Ferrero S, MacDonald TT, Pallone F, Monteleone G.

J Exp Med. 2011 Oct 24;208(11):2279-90. doi: 10.1084/jem.20111106. Epub 2011 Oct 10.

29.

2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression.

Stolfi C, Caruso R, Franzè E, Rizzo A, Rotondi A, Monteleone I, Fantini MC, Pallone F, Monteleone G.

Mol Cancer Ther. 2011 Oct;10(10):1969-81. doi: 10.1158/1535-7163.MCT-11-0316. Epub 2011 Aug 4.

30.

Inhibition of colitis by IL-25 associates with induction of alternatively activated macrophages.

Rizzo A, Monteleone I, Fina D, Stolfi C, Caruso R, Fantini MC, Franzè E, Schwendener R, Pallone F, Monteleone G.

Inflamm Bowel Dis. 2012 Mar;18(3):449-59. doi: 10.1002/ibd.21799. Epub 2011 Jun 17.

PMID:
21688353
31.

IL-21 promotes skin recruitment of CD4(+) cells and drives IFN-γ-dependent epidermal hyperplasia.

Sarra M, Caruso R, Cupi ML, Monteleone I, Stolfi C, Campione E, Diluvio L, Mazzotta A, Botti E, Chimenti S, Costanzo A, MacDonald TT, Pallone F, Monteleone G.

J Immunol. 2011 May 1;186(9):5435-42. doi: 10.4049/jimmunol.1003326. Epub 2011 Mar 25.

32.

The dual role of interleukin-25 in the control of immune-mediated pathologies.

Caruso R, Stolfi C, De Nitto D, Pallone F, Monteleone G.

Curr Mol Med. 2011 Feb;11(1):26-30. Review.

PMID:
21189120
33.

Interleukin-25 fails to activate STAT6 and induce alternatively activated macrophages.

Stolfi C, Caruso R, Franzè E, Sarra M, De Nitto D, Rizzo A, Pallone F, Monteleone G.

Immunology. 2011 Jan;132(1):66-77. doi: 10.1111/j.1365-2567.2010.03340.x. Epub 2010 Sep 14.

34.

Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases.

Sarra M, Monteleone I, Stolfi C, Fantini MC, Sileri P, Sica G, Tersigni R, Macdonald TT, Pallone F, Monteleone G.

Inflamm Bowel Dis. 2010 Aug;16(8):1332-9. doi: 10.1002/ibd.21238.

PMID:
20186935
35.

Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.

Stolfi C, Sarra M, Caruso R, Fantini MC, Fina D, Pellegrini R, Palmieri G, Macdonald TT, Pallone F, Monteleone G.

Gastroenterology. 2010 Jan;138(1):221-30. doi: 10.1053/j.gastro.2009.08.062. Epub 2009 Sep 6.

PMID:
19737563
36.

Involvement of interleukin-21 in the epidermal hyperplasia of psoriasis.

Caruso R, Botti E, Sarra M, Esposito M, Stolfi C, Diluvio L, Giustizieri ML, Pacciani V, Mazzotta A, Campione E, Macdonald TT, Chimenti S, Pallone F, Costanzo A, Monteleone G.

Nat Med. 2009 Sep;15(9):1013-5. doi: 10.1038/nm.1995. Epub 2009 Aug 16.

PMID:
19684581
37.

Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.

Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, MacDonald TT, Monteleone G.

Gastroenterology. 2009 Jun;136(7):2270-9. doi: 10.1053/j.gastro.2009.02.049.

PMID:
19505427
38.

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Fantini MC, Rizzo A, Fina D, Caruso R, Sarra M, Stolfi C, Becker C, Macdonald TT, Pallone F, Neurath MF, Monteleone G.

Gastroenterology. 2009 Apr;136(4):1308-16, e1-3. doi: 10.1053/j.gastro.2008.12.053. Epub 2008 Dec 27.

PMID:
19192480
39.

Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.

Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G.

Blood. 2009 Apr 9;113(15):3512-9. doi: 10.1182/blood-2008-08-172767. Epub 2009 Jan 7.

40.

The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathway.

Marinari B, Moretti F, Botti E, Giustizieri ML, Descargues P, Giunta A, Stolfi C, Ballaro C, Papoutsaki M, Alemà S, Monteleone G, Chimenti S, Karin M, Costanzo A.

Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17091-6. doi: 10.1073/pnas.0809288105. Epub 2008 Oct 28.

41.

Molecular basis of the potential of mesalazine to prevent colorectal cancer.

Stolfi C, Pellegrini R, Franze E, Pallone F, Monteleone G.

World J Gastroenterol. 2008 Jul 28;14(28):4434-9. Review.

42.

Transcriptional and post-translational regulation of Flip, an inhibitor of Fas-mediated apoptosis, in human gut inflammation.

Caprioli F, Stolfi C, Caruso R, Fina D, Sica G, Biancone L, Pallone F, Monteleone G.

Gut. 2008 Dec;57(12):1674-80. doi: 10.1136/gut.2008.149286. Epub 2008 Jul 14.

PMID:
18625693
43.

Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase.

Stolfi C, Fina D, Caruso R, Caprioli F, Fantini MC, Rizzo A, Sarra M, Pallone F, Monteleone G.

Carcinogenesis. 2008 Jun;29(6):1258-66. doi: 10.1093/carcin/bgn122. Epub 2008 May 20.

PMID:
18495657
44.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
45.

The AtMYB11 gene from Arabidopsis is expressed in meristematic cells and modulates growth in planta and organogenesis in vitro.

Petroni K, Falasca G, Calvenzani V, Allegra D, Stolfi C, Fabrizi L, Altamura MM, Tonelli C.

J Exp Bot. 2008;59(6):1201-13. doi: 10.1093/jxb/ern027. Epub 2008 Mar 20.

46.

Autocrine regulation of IL-21 production in human T lymphocytes.

Caprioli F, Sarra M, Caruso R, Stolfi C, Fina D, Sica G, MacDonald TT, Pallone F, Monteleone G.

J Immunol. 2008 Feb 1;180(3):1800-7.

47.

IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa.

Caruso R, Fina D, Paoluzi OA, Del Vecchio Blanco G, Stolfi C, Rizzo A, Caprioli F, Sarra M, Andrei F, Fantini MC, MacDonald TT, Pallone F, Monteleone G.

Eur J Immunol. 2008 Feb;38(2):470-8. doi: 10.1002/eji.200737635.

48.

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.

Stolfi C, Fina D, Caruso R, Caprioli F, Sarra M, Fantini MC, Rizzo A, Pallone F, Monteleone G.

Biochem Pharmacol. 2008 Feb 1;75(3):668-76. Epub 2007 Sep 29.

PMID:
17981262
49.

IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.

Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G.

J Immunol. 2007 May 1;178(9):5957-65.

50.

Lactobacillus paracasei subsp. paracasei B21060 suppresses human T-cell proliferation.

Peluso I, Fina D, Caruso R, Stolfi C, Caprioli F, Fantini MC, Caspani G, Grossi E, Di Iorio L, Paone FM, Pallone F, Monteleone G.

Infect Immun. 2007 Apr;75(4):1730-7. Epub 2007 Jan 22.

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