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Items: 29


Intravital imaging tumor screen used to identify novel metastasis-blocking therapeutic targets.

Stoletov K, Willetts L, Beatty PH, Lewis JD.

Cell Stress. 2018 Oct 4;2(10):275-278. doi: 10.15698/cst2018.10.159.


Quantitative in vivo whole genome motility screen reveals novel therapeutic targets to block cancer metastasis.

Stoletov K, Willetts L, Paproski RJ, Bond DJ, Raha S, Jovel J, Adam B, Robertson AE, Wong F, Woolner E, Sosnowski DL, Bismar TA, Wong GK, Zijlstra A, Lewis JD.

Nat Commun. 2018 Jun 14;9(1):2343. doi: 10.1038/s41467-018-04743-2.


LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis.

Ngan E, Stoletov K, Smith HW, Common J, Muller WJ, Lewis JD, Siegel PM.

Nat Commun. 2017 Apr 24;8:15059. doi: 10.1038/ncomms15059.


Functional assessment of von Willebrand factor expression by cancer cells of non-endothelial origin.

Mojiri A, Stoletov K, Carrillo MA, Willetts L, Jain S, Godbout R, Jurasz P, Sergi CM, Eisenstat DD, Lewis JD, Jahroudi N.

Oncotarget. 2017 Feb 21;8(8):13015-13029. doi: 10.18632/oncotarget.14273.


Quantitative Analysis of Human Cancer Cell Extravasation Using Intravital Imaging.

Willetts L, Bond D, Stoletov K, Lewis JD.

Methods Mol Biol. 2016;1458:27-37. doi: 10.1007/978-1-4939-3801-8_3.


Ankyrin G expression is associated with androgen receptor stability, invasiveness, and lethal outcome in prostate cancer patients.

Wang T, Abou-Ouf H, Hegazy SA, Alshalalfa M, Stoletov K, Lewis J, Donnelly B, Bismar TA.

J Mol Med (Berl). 2016 Dec;94(12):1411-1422. Epub 2016 Aug 18.


Invadopodia: a new therapeutic target to block cancer metastasis.

Stoletov K, Lewis JD.

Expert Rev Anticancer Ther. 2015;15(7):733-5. doi: 10.1586/14737140.2015.1058711. Epub 2015 Jun 22.


Metastasis as a therapeutic target in prostate cancer: a conceptual framework.

Stoletov K, Bond D, Hebron K, Raha S, Zijlstra A, Lewis JD.

Am J Clin Exp Urol. 2014 Apr;2(1):45-56.


Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis.

Leong HS, Robertson AE, Stoletov K, Leith SJ, Chin CA, Chien AE, Hague MN, Ablack A, Carmine-Simmen K, McPherson VA, Postenka CO, Turley EA, Courtneidge SA, Chambers AF, Lewis JD.

Cell Rep. 2014 Sep 11;8(5):1558-70. doi: 10.1016/j.celrep.2014.07.050. Epub 2014 Aug 28.


Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.

Golubkov VS, Prigozhina NL, Zhang Y, Stoletov K, Lewis JD, Schwartz PE, Hoffman RM, Strongin AY.

J Biol Chem. 2014 Aug 29;289(35):24238-49. doi: 10.1074/jbc.M114.574459. Epub 2014 Jul 8.


Role of connexins in metastatic breast cancer and melanoma brain colonization.

Stoletov K, Strnadel J, Zardouzian E, Momiyama M, Park FD, Kelber JA, Pizzo DP, Hoffman R, VandenBerg SR, Klemke RL.

J Cell Sci. 2013 Feb 15;126(Pt 4):904-13. doi: 10.1242/jcs.112748. Epub 2013 Jan 15.


KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer.

Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL.

Cancer Res. 2012 May 15;72(10):2554-64. doi: 10.1158/0008-5472.CAN-11-3552.


Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells.

Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL.

Cancer Res. 2010 Nov 1;70(21):8948-58. doi: 10.1158/0008-5472.CAN-10-1936. Epub 2010 Oct 12.


A PKA-Csk-pp60Src signaling pathway regulates the switch between endothelial cell invasion and cell-cell adhesion during vascular sprouting.

Jin H, Garmy-Susini B, Avraamides CJ, Stoletov K, Klemke RL, Varner JA.

Blood. 2010 Dec 16;116(25):5773-83. doi: 10.1182/blood-2010-07-296210. Epub 2010 Sep 8.


Visualizing extravasation dynamics of metastatic tumor cells.

Stoletov K, Kato H, Zardouzian E, Kelber J, Yang J, Shattil S, Klemke R.

J Cell Sci. 2010 Jul 1;123(Pt 13):2332-41. doi: 10.1242/jcs.069443. Epub 2010 Jun 8.


Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF.

Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, Tsigelny I, Saldanha A, Walsh B, Hoffman RM, Bouvet M, Klemke RL, Vogt PK, Arnold L, Wrasidlo W, Cheresh DA.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4299-304. doi: 10.1073/pnas.0909299107. Epub 2010 Feb 12.


Vascular lipid accumulation, lipoprotein oxidation, and macrophage lipid uptake in hypercholesterolemic zebrafish.

Stoletov K, Fang L, Choi SH, Hartvigsen K, Hansen LF, Hall C, Pattison J, Juliano J, Miller ER, Almazan F, Crosier P, Witztum JL, Klemke RL, Miller YI.

Circ Res. 2009 Apr 24;104(8):952-60. doi: 10.1161/CIRCRESAHA.108.189803. Epub 2009 Mar 5.


Catch of the day: zebrafish as a human cancer model.

Stoletov K, Klemke R.

Oncogene. 2008 Jul 31;27(33):4509-20. doi: 10.1038/onc.2008.95. Epub 2008 Mar 31. Review.


The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8.

Wrasidlo W, Mielgo A, Torres VA, Barbero S, Stoletov K, Suyama TL, Klemke RL, Gerwick WH, Carson DA, Stupack DG.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2313-8. doi: 10.1073/pnas.0712198105. Epub 2008 Feb 11.


High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish.

Stoletov K, Montel V, Lester RD, Gonias SL, Klemke R.

Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17406-11. Epub 2007 Oct 22.


VEGF treatment induces signaling pathways that regulate both actin polymerization and depolymerization.

Gong C, Stoletov KV, Terman BI.

Angiogenesis. 2004;7(4):313-21. Epub 2005 May 9.


Bmx is a downstream Rap1 effector in VEGF-induced endothelial cell activation.

Stoletov KV, Terman BI.

Biochem Biophys Res Commun. 2004 Jul 16;320(1):70-5.


Sck is expressed in endothelial cells and participates in vascular endothelial growth factor-induced signaling.

Ratcliffe KE, Tao Q, Yavuz B, Stoletov KV, Spring SC, Terman BI.

Oncogene. 2002 Sep 12;21(41):6307-16.


Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling.

Stoletov KV, Ratcliffe KE, Terman BI.

FASEB J. 2002 Aug;16(10):1283-5. Epub 2002 Jun 21.


Molecular vehicles for targeted drug delivery.

Backer MV, Aloise R, Przekop K, Stoletov K, Backer JM.

Bioconjug Chem. 2002 May-Jun;13(3):462-7.


NCK and PAK participate in the signaling pathway by which vascular endothelial growth factor stimulates the assembly of focal adhesions.

Stoletov KV, Ratcliffe KE, Spring SC, Terman BI.

J Biol Chem. 2001 Jun 22;276(25):22748-55. Epub 2001 Mar 8.


Formation of the D-loop structure complexes between DNA and oligonucleotides and affinity modification of DNA by chemically reactive derivatives of oligonucleotides lead to the recombination.

Sinitsina OI, Stoletov KV, Bugreev DV, Maksakova GA, Bugreeva IF, Vasyunina EA, Nevinsky GA.

Med Sci Monit. 2000 Jul-Aug;6(4):653-7.


[Induction of recombination in adducts oligonucleotide-DNA produced by affinity modification of DNA].

Sinitsina OI, Stoletov KV, Maksakova GA, Vasiunina EA, Nevinskiń≠ GA.

Dokl Akad Nauk. 1997 Sep;356(3):404-6. Russian. No abstract available.


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