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Items: 45

1.

SAR Exploration of Tight-Binding Inhibitors of Influenza Virus PA Endonuclease.

Credille CV, Morrison CN, Stokes RW, Dick BL, Feng Y, Sun J, Chen Y, Cohen SM.

J Med Chem. 2019 Oct 17. doi: 10.1021/acs.jmedchem.9b00747. [Epub ahead of print]

PMID:
31536340
2.

Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease.

Credille CV, Dick BL, Morrison CN, Stokes RW, Adamek RN, Wu NC, Wilson IA, Cohen SM.

J Med Chem. 2018 Nov 21;61(22):10206-10217. doi: 10.1021/acs.jmedchem.8b01363. Epub 2018 Oct 31.

PMID:
30351002
3.

4-Cyanobenzenesulfonamides: Amine Synthesis and Protecting Strategy To Compliment the Nosyl Group.

Schmidt MA, Stokes RW, Davies ML, Roberts F.

J Org Chem. 2017 May 5;82(9):4550-4560. doi: 10.1021/acs.joc.7b00608. Epub 2017 Apr 19.

PMID:
28410437
4.

Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt-Ti catalysts.

Talley MR, Stokes RW, Walker WK, Michaelis DJ.

Dalton Trans. 2016 Jun 14;45(24):9770-3. doi: 10.1039/c6dt01783e.

PMID:
27240482
5.

Allylic aminations with hindered secondary amine nucleophiles catalyzed by heterobimetallic Pd-Ti complexes.

Walker WK, Anderson DL, Stokes RW, Smith SJ, Michaelis DJ.

Org Lett. 2015 Feb 6;17(3):752-5. doi: 10.1021/acs.orglett.5b00058. Epub 2015 Jan 22.

PMID:
25612096
6.

Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.

Sun J, Singh V, Lau A, Stokes RW, Obregón-Henao A, Orme IM, Wong D, Av-Gay Y, Hmama Z.

PLoS Pathog. 2013;9(7):e1003499. doi: 10.1371/journal.ppat.1003499. Epub 2013 Jul 18.

7.

Mycobacterium tuberculosis employs Cpn60.2 as an adhesin that binds CD43 on the macrophage surface.

Hickey TB, Ziltener HJ, Speert DP, Stokes RW.

Cell Microbiol. 2010 Nov;12(11):1634-47. doi: 10.1111/j.1462-5822.2010.01496.x.

PMID:
20633027
8.

Contrasting transcriptional responses of a virulent and an attenuated strain of Mycobacterium tuberculosis infecting macrophages.

Li AH, Waddell SJ, Hinds J, Malloff CA, Bains M, Hancock RE, Lam WL, Butcher PD, Stokes RW.

PLoS One. 2010 Jun 10;5(6):e11066. doi: 10.1371/journal.pone.0011066.

9.

Adjusting to a new home: Mycobacterium tuberculosis gene expression in response to an intracellular lifestyle.

Stokes RW, Waddell SJ.

Future Microbiol. 2009 Dec;4(10):1317-35. doi: 10.2217/fmb.09.94. Review.

PMID:
19995191
10.

Mycobacterium tuberculosis Cpn60.2 and DnaK are located on the bacterial surface, where Cpn60.2 facilitates efficient bacterial association with macrophages.

Hickey TB, Thorson LM, Speert DP, Daffé M, Stokes RW.

Infect Immun. 2009 Aug;77(8):3389-401. doi: 10.1128/IAI.00143-09. Epub 2009 May 26.

11.

Bacterial artificial chromosome fingerprint arrays for the differentiation of transcriptomic differences in mycobacteria.

Li AH, Lam WL, Stokes RW.

J Microbiol Methods. 2008 Dec;75(3):416-24. doi: 10.1016/j.mimet.2008.07.008. Epub 2008 Jul 20.

PMID:
18706942
12.
13.

CD43 controls the intracellular growth of Mycobacterium tuberculosis through the induction of TNF-alpha-mediated apoptosis.

Randhawa AK, Ziltener HJ, Stokes RW.

Cell Microbiol. 2008 Oct;10(10):2105-17. doi: 10.1111/j.1462-5822.2008.01194.x. Epub 2008 Jul 10.

PMID:
18637079
16.

CD43 is required for optimal growth inhibition of Mycobacterium tuberculosis in macrophages and in mice.

Randhawa AK, Ziltener HJ, Merzaban JS, Stokes RW.

J Immunol. 2005 Aug 1;175(3):1805-12.

17.

Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis.

Wang J, Thorson L, Stokes RW, Santosuosso M, Huygen K, Zganiacz A, Hitt M, Xing Z.

J Immunol. 2004 Nov 15;173(10):6357-65.

18.
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The Mycobacterium tuberculosis protein serine/threonine kinase PknG is linked to cellular glutamate/glutamine levels and is important for growth in vivo.

Cowley S, Ko M, Pick N, Chow R, Downing KJ, Gordhan BG, Betts JC, Mizrahi V, Smith DA, Stokes RW, Av-Gay Y.

Mol Microbiol. 2004 Jun;52(6):1691-702.

20.

Two-dimensional bacterial genome display: a method for the genomic analysis of mycobacteria.

Dullaghan EM, Malloff CA, Li AH, Lam WL, Stokes RW.

Microbiology. 2002 Oct;148(Pt 10):3111-7.

PMID:
12368444
21.

Two-dimensional display and whole genome comparison of bacterial pathogen genomes of high G+C DNA content.

Malloff CA, Fernandez RC, Dullaghan EM, Stokes RW, Lam WL.

Gene. 2002 Jun 26;293(1-2):205-11.

PMID:
12137959
22.

Two distinct receptors mediate nonopsonic phagocytosis of different strains of Pseudomonas aeruginosa.

Heale JP, Pollard AJ, Stokes RW, Simpson D, Tsang A, Massing B, Speert DP.

J Infect Dis. 2001 Apr 15;183(8):1214-20. Epub 2001 Mar 15.

PMID:
11262203
23.

Effect of mycobacterial phospholipids on interaction of Mycobacterium tuberculosis with macrophages.

Thorson LM, Doxsee D, Scott MG, Wheeler P, Stokes RW.

Infect Immun. 2001 Apr;69(4):2172-9.

24.
27.

Enhanced gene replacement in mycobacteria.

Hinds J, Mahenthiralingam E, Kempsell KE, Duncan K, Stokes RW, Parish T, Stoker NG.

Microbiology. 1999 Mar;145 ( Pt 3):519-27.

PMID:
10217485
28.

Gene replacement in Mycobacterium intracellulare.

Marklund BI, Stokes RW.

Methods Mol Biol. 1998;101:217-24. No abstract available.

PMID:
9921481
29.

Site-directed mutagenesis and virulence assessment of the katG gene of Mycobacterium intracellulare.

Marklund BI, Mahenthiralingam E, Stokes RW.

Mol Microbiol. 1998 Aug;29(4):999-1008.

30.
31.
32.

Antimycobacterial polyynes of Devil's Club (Oplopanax horridus), a North American native medicinal plant.

Kobaisy M, Abramowski Z, Lermer L, Saxena G, Hancock RE, Towers GH, Doxsee D, Stokes RW.

J Nat Prod. 1997 Nov;60(11):1210-3.

PMID:
9392889
33.

Mycobacterium tuberculosis efpA encodes an efflux protein of the QacA transporter family.

Doran JL, Pang Y, Mdluli KE, Moran AJ, Victor TC, Stokes RW, Mahenthiralingam E, Kreiswirth BN, Butt JL, Baron GS, Treit JD, Kerr VJ, Van Helden PD, Roberts MC, Nano FE.

Clin Diagn Lab Immunol. 1997 Jan;4(1):23-32.

34.

Gene replacement through homologous recombination in Mycobacterium intracellulare.

Marklund BI, Speert DP, Stokes RW.

J Bacteriol. 1995 Nov;177(21):6100-5.

35.
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37.
38.
40.

Mycobacterium avium-complex infections in normal and immunodeficient mice.

Collins FM, Stokes RW.

Tubercle. 1987 Jun;68(2):127-36.

PMID:
2958962
41.

A method for the purification of Leishmania promastigotes from infected phlebotomine sandflies.

Stephenson G, Stokes RW, Ward RD.

Ann Trop Med Parasitol. 1987 Feb;81(1):15-23.

PMID:
3675038
42.
43.

Genetic control of natural resistance to nontuberculous mycobacterial infections in mice.

Orme IM, Stokes RW, Collins FM.

Infect Immun. 1986 Oct;54(1):56-62.

44.

Neurofibromatosis: review of the literature.

Stokes RW.

J Am Osteopath Assoc. 1986 Jan;86(1):49-52. Review. No abstract available.

PMID:
3081471
45.

Recurrent aphthous stomatitis: review of the literature.

Stokes RW, Koprince D.

J Am Osteopath Assoc. 1982 Jul;81(11):776-82. Review. No abstract available.

PMID:
6214531

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