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Items: 1 to 50 of 100

1.

Use of whole-genome sequencing to distinguish relapse from reinfection in a completed tuberculosis clinical trial.

Witney AA, Bateson AL, Jindani A, Phillips PP, Coleman D, Stoker NG, Butcher PD, McHugh TD; RIFAQUIN Study Team.

BMC Med. 2017 Mar 29;15(1):71. doi: 10.1186/s12916-017-0834-4.

2.

Clinical use of whole genome sequencing for Mycobacterium tuberculosis.

Witney AA, Cosgrove CA, Arnold A, Hinds J, Stoker NG, Butcher PD.

BMC Med. 2016 Mar 23;14:46. doi: 10.1186/s12916-016-0598-2. Review.

3.

Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases.

Witney AA, Gould KA, Arnold A, Coleman D, Delgado R, Dhillon J, Pond MJ, Pope CF, Planche TD, Stoker NG, Cosgrove CA, Butcher PD, Harrison TS, Hinds J.

J Clin Microbiol. 2015 May;53(5):1473-83. doi: 10.1128/JCM.02993-14. Epub 2015 Feb 11.

4.

Genome sequencing and characterization of an extensively drug-resistant sequence type 111 serotype O12 hospital outbreak strain of Pseudomonas aeruginosa.

Witney AA, Gould KA, Pope CF, Bolt F, Stoker NG, Cubbon MD, Bradley CR, Fraise A, Breathnach AS, Butcher PD, Planche TD, Hinds J.

Clin Microbiol Infect. 2014 Oct;20(10):O609-18. doi: 10.1111/1469-0691.12528. Epub 2014 Feb 8.

5.

bkaR is a TetR-type repressor that controls an operon associated with branched-chain keto-acid metabolism in Mycobacteria.

Balhana RJ, Swanston SN, Coade S, Withers M, Sikder MH, Stoker NG, Kendall SL.

FEMS Microbiol Lett. 2013 Aug;345(2):132-40. doi: 10.1111/1574-6968.12196. Epub 2013 Jul 8.

6.

Cholesterol metabolism in Mycobacterium smegmatis.

Uhía I, Galán B, Kendall SL, Stoker NG, García JL.

Environ Microbiol Rep. 2012 Apr;4(2):168-82. doi: 10.1111/j.1758-2229.2011.00314.x. Epub 2012 Jan 12.

PMID:
23757270
7.

BμG@Sbase--a microbial gene expression and comparative genomic database.

Witney AA, Waldron DE, Brooks LA, Tyler RH, Withers M, Stoker NG, Wren BW, Butcher PD, Hinds J.

Nucleic Acids Res. 2012 Jan;40(Database issue):D605-9. doi: 10.1093/nar/gkr796. Epub 2011 Sep 24.

8.

Rapid construction of mycobacterial mutagenesis vectors using ligation-independent cloning.

Balhana R, Stoker NG, Sikder MH, Chauviac FX, Kendall SL.

J Microbiol Methods. 2010 Oct;83(1):34-41. doi: 10.1016/j.mimet.2010.07.014. Epub 2010 Jul 27.

9.

Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2.

Kendall SL, Burgess P, Balhana R, Withers M, Ten Bokum A, Lott JS, Gao C, Uhia-Castro I, Stoker NG.

Microbiology. 2010 May;156(Pt 5):1362-71. doi: 10.1099/mic.0.034538-0. Epub 2010 Feb 18.

10.

Inositol monophosphate phosphatase genes of Mycobacterium tuberculosis.

Movahedzadeh F, Wheeler PR, Dinadayala P, Av-Gay Y, Parish T, Daffé M, Stoker NG.

BMC Microbiol. 2010 Feb 18;10:50. doi: 10.1186/1471-2180-10-50.

11.

Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis.

Kana BD, Abrahams GL, Sung N, Warner DF, Gordhan BG, Machowski EE, Tsenova L, Sacchettini JC, Stoker NG, Kaplan G, Mizrahi V.

J Bacteriol. 2010 Apr;192(8):2220-7. doi: 10.1128/JB.01135-09. Epub 2010 Feb 5.

12.

The case for hypervirulence through gene deletion in Mycobacterium tuberculosis.

ten Bokum AM, Movahedzadeh F, Frita R, Bancroft GJ, Stoker NG.

Trends Microbiol. 2008 Sep;16(9):436-41. doi: 10.1016/j.tim.2008.06.003. Epub 2008 Aug 11. Review.

PMID:
18701293
13.

Microarray analysis of bacterial gene expression: towards the regulome.

Kendall SL, Movahedzadeh F, Wietzorrek A, Stoker NG.

Comp Funct Genomics. 2002;3(4):352-4. doi: 10.1002/cfg.193.

14.

Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex.

Sidders B, Pirson C, Hogarth PJ, Hewinson RG, Stoker NG, Vordermeier HM, Ewer K.

Infect Immun. 2008 Sep;76(9):3932-9. doi: 10.1128/IAI.00150-08. Epub 2008 Jun 2.

15.

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages.

Tailleux L, Waddell SJ, Pelizzola M, Mortellaro A, Withers M, Tanne A, Castagnoli PR, Gicquel B, Stoker NG, Butcher PD, Foti M, Neyrolles O.

PLoS One. 2008 Jan 2;3(1):e1403. doi: 10.1371/journal.pone.0001403.

16.

Quantification of global transcription patterns in prokaryotes using spotted microarrays.

Sidders B, Withers M, Kendall SL, Bacon J, Waddell SJ, Hinds J, Golby P, Movahedzadeh F, Cox RA, Frita R, Ten Bokum AM, Wernisch L, Stoker NG.

Genome Biol. 2007;8(12):R265.

17.

The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction.

Appelmelk BJ, den Dunnen J, Driessen NN, Ummels R, Pak M, Nigou J, Larrouy-Maumus G, Gurcha SS, Movahedzadeh F, Geurtsen J, Brown EJ, Eysink Smeets MM, Besra GS, Willemsen PT, Lowary TL, van Kooyk Y, Maaskant JJ, Stoker NG, van der Ley P, Puzo G, Vandenbroucke-Grauls CM, Wieland CW, van der Poll T, Geijtenbeek TB, van der Sar AM, Bitter W.

Cell Microbiol. 2008 Apr;10(4):930-44. Epub 2007 Dec 5.

PMID:
18070119
18.

Mycobacterial cells have dual nickel-cobalt sensors: sequence relationships and metal sites of metal-responsive repressors are not congruent.

Campbell DR, Chapman KE, Waldron KJ, Tottey S, Kendall S, Cavallaro G, Andreini C, Hinds J, Stoker NG, Robinson NJ, Cavet JS.

J Biol Chem. 2007 Nov 2;282(44):32298-310. Epub 2007 Aug 28.

19.

A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis.

Kendall SL, Withers M, Soffair CN, Moreland NJ, Gurcha S, Sidders B, Frita R, Ten Bokum A, Besra GS, Lott JS, Stoker NG.

Mol Microbiol. 2007 Aug;65(3):684-99.

20.

RNA profiling in host-pathogen interactions.

Waddell SJ, Butcher PD, Stoker NG.

Curr Opin Microbiol. 2007 Jun;10(3):297-302. Epub 2007 Jun 15. Review.

21.

Lipid composition and transcriptional response of Mycobacterium tuberculosis grown under iron-limitation in continuous culture: identification of a novel wax ester.

Bacon J, Dover LG, Hatch KA, Zhang Y, Gomes JM, Kendall S, Wernisch L, Stoker NG, Butcher PD, Besra GS, Marsh PD.

Microbiology. 2007 May;153(Pt 5):1435-44.

23.
24.

A derivative of Mycobacterium smegmatis mc(2)155 that lacks the duplicated chromosomal region.

Warner DF, Etienne G, Wang XM, Matsoso LG, Dawes SS, Soetaert K, Stoker NG, Content J, Mizrahi V.

Tuberculosis (Edinb). 2006 Nov;86(6):438-44. Epub 2005 Dec 15.

PMID:
16359921
25.

Identification of specific proteins and peptides in Mycobacterium leprae suitable for the selective diagnosis of leprosy.

Spencer JS, Dockrell HM, Kim HJ, Marques MA, Williams DL, Martins MV, Martins ML, Lima MC, Sarno EN, Pereira GM, Matos H, Fonseca LS, Sampaio EP, Ottenhoff TH, Geluk A, Cho SN, Stoker NG, Cole ST, Brennan PJ, Pessolani MC.

J Immunol. 2005 Dec 15;175(12):7930-8.

26.

A GAF domain in the hypoxia/NO-inducible Mycobacterium tuberculosis DosS protein binds haem.

Sardiwal S, Kendall SL, Movahedzadeh F, Rison SC, Stoker NG, Djordjevic S.

J Mol Biol. 2005 Nov 11;353(5):929-36. Epub 2005 Sep 27.

PMID:
16213520
27.

A universally applicable method of operon map prediction on minimally annotated genomes using conserved genomic context.

Edwards MT, Rison SC, Stoker NG, Wernisch L.

Nucleic Acids Res. 2005 Jun 7;33(10):3253-62. Print 2005.

28.

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.

Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD.

Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. Epub 2005 Jan 20.

PMID:
15687025
29.

What do microarrays really tell us about M. tuberculosis?

Kendall SL, Rison SC, Movahedzadeh F, Frita R, Stoker NG.

Trends Microbiol. 2004 Dec;12(12):537-44. Review.

PMID:
15539113
30.

The Mycobacterium tuberculosis Rv1099c gene encodes a GlpX-like class II fructose 1,6-bisphosphatase.

Movahedzadeh F, Rison SC, Wheeler PR, Kendall SL, Larson TJ, Stoker NG.

Microbiology. 2004 Oct;150(Pt 10):3499-505.

PMID:
15470127
31.

The Mycobacterium tuberculosis sigJ gene controls sensitivity of the bacterium to hydrogen peroxide.

Hu Y, Kendall S, Stoker NG, Coates AR.

FEMS Microbiol Lett. 2004 Aug 15;237(2):415-23.

32.

The Mycobacterium tuberculosis dosRS two-component system is induced by multiple stresses.

Kendall SL, Movahedzadeh F, Rison SC, Wernisch L, Parish T, Duncan K, Betts JC, Stoker NG.

Tuberculosis (Edinb). 2004;84(3-4):247-55.

PMID:
15207494
33.

The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosis.

Bacon J, James BW, Wernisch L, Williams A, Morley KA, Hatch GJ, Mangan JA, Hinds J, Stoker NG, Butcher PD, Marsh PD.

Tuberculosis (Edinb). 2004;84(3-4):205-17.

PMID:
15207490
34.

The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.

Movahedzadeh F, Smith DA, Norman RA, Dinadayala P, Murray-Rust J, Russell DG, Kendall SL, Rison SC, McAlister MS, Bancroft GJ, McDonald NQ, Daffe M, Av-Gay Y, Stoker NG.

Mol Microbiol. 2004 Feb;51(4):1003-14.

35.

The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence.

Parish T, Smith DA, Roberts G, Betts J, Stoker NG.

Microbiology. 2003 Jun;149(Pt 6):1423-35.

PMID:
12777483
36.

Deletion of two-component regulatory systems increases the virulence of Mycobacterium tuberculosis.

Parish T, Smith DA, Kendall S, Casali N, Bancroft GJ, Stoker NG.

Infect Immun. 2003 Mar;71(3):1134-40.

37.

Gene replacement in mycobacteria by using incompatible plasmids.

Pashley CA, Parish T, McAdam RA, Duncan K, Stoker NG.

Appl Environ Microbiol. 2003 Jan;69(1):517-23.

38.

Analysis of whole-genome microarray replicates using mixed models.

Wernisch L, Kendall SL, Soneji S, Wietzorrek A, Parish T, Hinds J, Butcher PD, Stoker NG.

Bioinformatics. 2003 Jan;19(1):53-61.

PMID:
12499293
39.

The common aromatic amino acid biosynthesis pathway is essential in Mycobacterium tuberculosis.

Parish T, Stoker NG.

Microbiology. 2002 Oct;148(Pt 10):3069-77.

PMID:
12368440
40.

Crystal structure of inositol 1-phosphate synthase from Mycobacterium tuberculosis, a key enzyme in phosphatidylinositol synthesis.

Norman RA, McAlister MS, Murray-Rust J, Movahedzadeh F, Stoker NG, McDonald NQ.

Structure. 2002 Mar;10(3):393-402.

41.

Use of the mycobacteriophage L5 excisionase in Mycobacterium tuberculosis to demonstrate gene essentiality.

Parish T, Lewis J, Stoker NG.

Tuberculosis (Edinb). 2001;81(5-6):359-64.

PMID:
11800587
42.

Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity.

Dorrell N, Mangan JA, Laing KG, Hinds J, Linton D, Al-Ghusein H, Barrell BG, Parkhill J, Stoker NG, Karlyshev AV, Butcher PD, Wren BW.

Genome Res. 2001 Oct;11(10):1706-15.

43.

amiA is a negative regulator of acetamidase expression in Mycobacterium smegmatis.

Parish T, Turner J, Stoker NG.

BMC Microbiol. 2001;1:19. Epub 2001 Aug 31.

44.

Characterization of auxotrophic mutants of Mycobacterium tuberculosis and their potential as vaccine candidates.

Smith DA, Parish T, Stoker NG, Bancroft GJ.

Infect Immun. 2001 Feb;69(2):1142-50.

45.

Sequence diversity of a fragment of the 16S RNA gene from Helicobacter pylori.

Khan MM, Stoker NG, Drasar BS.

Microbios. 2000;103(406):139-50.

PMID:
11131807
46.

glnE is an essential gene in Mycobacterium tuberculosis.

Parish T, Stoker NG.

J Bacteriol. 2000 Oct;182(20):5715-20.

47.

Mycobacteria: bugs and bugbears (two steps forward and one step back).

Parish T, Stoker NG.

Mol Biotechnol. 1999 Dec 15;13(3):191-200. Review.

PMID:
10934532
48.
49.

Rapid screening of Mycobacterium tuberculosis for susceptibility to rifampicin and streptomycin.

McNerney R, Kiepiela P, Bishop KS, Nye PM, Stoker NG.

Int J Tuberc Lung Dis. 2000 Jan;4(1):69-75.

PMID:
10654647
50.

Production of mutants in amino acid biosynthesis genes of Mycobacterium tuberculosis by homologous recombination.

Parish T, Gordhan BG, McAdam RA, Duncan K, Mizrahi V, Stoker NG.

Microbiology. 1999 Dec;145 ( Pt 12):3497-503.

PMID:
10627047

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