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Items: 1 to 50 of 95

1.

Plant-derived protein bodies as a delivery vehicle for recombinant proteins into mammalian cells.

Schwestka J, Tschofen M, Vogt S, Marcel S, Grillari J, Raith M, Swoboda I, Stoger E.

Biotechnol Bioeng. 2020 Jan 20. doi: 10.1002/bit.27273. [Epub ahead of print]

PMID:
31956981
2.

Russell-Like Bodies in Plant Seeds Share Common Features With Prolamin Bodies and Occur Upon Recombinant Protein Production.

Arcalis E, Ibl V, Hilscher J, Rademacher T, Avesani L, Morandini F, Bortesi L, Pezzotti M, Vitale A, Pum D, De Meyer T, Depicker A, Stoger E.

Front Plant Sci. 2019 Jun 26;10:777. doi: 10.3389/fpls.2019.00777. eCollection 2019.

3.

Extracellular Vesicles in Human Skin: Cross-Talk from Senescent Fibroblasts to Keratinocytes by miRNAs.

Terlecki-Zaniewicz L, Pils V, Bobbili MR, Lämmermann I, Perrotta I, Grillenberger T, Schwestka J, Weiß K, Pum D, Arcalis E, Schwingenschuh S, Birngruber T, Brandstetter M, Heuser T, Schosserer M, Morizot F, Mildner M, Stöger E, Tschachler E, Weinmüllner R, Gruber F, Grillari J.

J Invest Dermatol. 2019 Dec;139(12):2425-2436.e5. doi: 10.1016/j.jid.2019.05.015. Epub 2019 Jun 18.

PMID:
31220456
4.

Microscopic and Proteomic Analysis of Dissected Developing Barley Endosperm Layers Reveals the Starchy Endosperm as Prominent Storage Tissue for ER-Derived Hordeins Alongside the Accumulation of Barley Protein Disulfide Isomerase (HvPDIL1-1).

Roustan V, Roustan PJ, Weidinger M, Reipert S, Kapusi E, Shabrangy A, Stoger E, Weckwerth W, Ibl V.

Front Plant Sci. 2018 Sep 10;9:1248. doi: 10.3389/fpls.2018.01248. eCollection 2018.

5.

Maize 16-kD γ-zein forms very unusual disulfide-bonded polymers in the endoplasmic reticulum: implications for prolamin evolution.

Mainieri D, Marrano CA, Prinsi B, Maffi D, Tschofen M, Espen L, Stöger E, Faoro F, Pedrazzini E, Vitale A.

J Exp Bot. 2018 Oct 12;69(21):5013-5027. doi: 10.1093/jxb/ery287.

6.

Glyco-Engineering of Plant-Based Expression Systems.

Fischer R, Holland T, Sack M, Schillberg S, Stoger E, Twyman RM, Buyel JF.

Adv Biochem Eng Biotechnol. 2018 Aug 2. doi: 10.1007/10_2018_76. [Epub ahead of print]

PMID:
30069741
7.

Using RT-qPCR, Proteomics, and Microscopy to Unravel the Spatio-Temporal Expression and Subcellular Localization of Hordoindolines Across Development in Barley Endosperm.

Shabrangy A, Roustan V, Reipert S, Weidinger M, Roustan PJ, Stoger E, Weckwerth W, Ibl V.

Front Plant Sci. 2018 Jun 13;9:775. doi: 10.3389/fpls.2018.00775. eCollection 2018.

8.
9.

A Welcome Proposal to Amend the GMO Legislation of the EU.

Eriksson D, Harwood W, Hofvander P, Jones H, Rogowsky P, Stöger E, Visser RGF.

Trends Biotechnol. 2018 Nov;36(11):1100-1103. doi: 10.1016/j.tibtech.2018.05.001. Epub 2018 May 25.

10.

Imaging the ER and Endomembrane System in Cereal Endosperm.

Ibl V, Peters J, Stöger E, Arcalís E.

Methods Mol Biol. 2018;1691:251-262. doi: 10.1007/978-1-4939-7389-7_20.

PMID:
29043684
11.

Quality Standards for Herbal Drugs and Herbal Drug Preparations - Appropriate or Improvements Necessary?

Länger R, Stöger E, Kubelka W, Helliwell K.

Planta Med. 2018 Apr;84(6-07):350-360. doi: 10.1055/s-0043-118534. Epub 2017 Aug 29.

PMID:
28850958
12.

LALF32-51 -E7, a HPV-16 therapeutic vaccine candidate, forms protein body-like structures when expressed in Nicotiana benthamiana leaves.

Yanez RJR, Lamprecht R, Granadillo M, Torrens I, Arcalís E, Stöger E, Rybicki EP, Hitzeroth II.

Plant Biotechnol J. 2018 Feb;16(2):628-637. doi: 10.1111/pbi.12802. Epub 2017 Sep 7.

13.

Heritable Genomic Fragment Deletions and Small Indels in the Putative ENGase Gene Induced by CRISPR/Cas9 in Barley.

Kapusi E, Corcuera-Gómez M, Melnik S, Stoger E.

Front Plant Sci. 2017 Apr 25;8:540. doi: 10.3389/fpls.2017.00540. eCollection 2017.

14.

Cloning and plant-based production of antibody MC10E7 for a lateral flow immunoassay to detect [4-arginine]microcystin in freshwater.

Melnik S, Neumann AC, Karongo R, Dirndorfer S, Stübler M, Ibl V, Niessner R, Knopp D, Stoger E.

Plant Biotechnol J. 2018 Jan;16(1):27-38. doi: 10.1111/pbi.12746. Epub 2017 Jun 5.

15.

Targeted modification of plant genomes for precision crop breeding.

Hilscher J, Bürstmayr H, Stoger E.

Biotechnol J. 2017 Jan;12(1). doi: 10.1002/biot.201600173. Epub 2016 Oct 11. Review.

PMID:
27726285
16.

Plant Molecular Farming: Much More than Medicines.

Tschofen M, Knopp D, Hood E, Stöger E.

Annu Rev Anal Chem (Palo Alto Calif). 2016 Jun 12;9(1):271-94. doi: 10.1146/annurev-anchem-071015-041706. Epub 2016 Mar 30. Review.

PMID:
27049632
17.

The Encapsulation of Hemagglutinin in Protein Bodies Achieves a Stronger Immune Response in Mice than the Soluble Antigen.

Hofbauer A, Melnik S, Tschofen M, Arcalis E, Phan HT, Gresch U, Lampel J, Conrad U, Stoger E.

Front Plant Sci. 2016 Feb 16;7:142. doi: 10.3389/fpls.2016.00142. eCollection 2016.

18.

The case for plant-made veterinary immunotherapeutics.

Topp E, Irwin R, McAllister T, Lessard M, Joensuu JJ, Kolotilin I, Conrad U, Stöger E, Mor T, Warzecha H, Hall JC, McLean MD, Cox E, Devriendt B, Potter A, Depicker A, Virdi V, Holbrook L, Doshi K, Dussault M, Friendship R, Yarosh O, Yoo HS, MacDonald J, Menassa R.

Biotechnol Adv. 2016 Sep-Oct;34(5):597-604. doi: 10.1016/j.biotechadv.2016.02.007. Epub 2016 Feb 12. Review.

PMID:
26875776
19.

Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV.

Vamvaka E, Arcalis E, Ramessar K, Evans A, O'Keefe BR, Shattock RJ, Medina V, Stöger E, Christou P, Capell T.

Plant Biotechnol J. 2016 Jun;14(6):1427-37. doi: 10.1111/pbi.12507. Epub 2016 Jan 23.

20.

Transgenic Production of an Anti HIV Antibody in the Barley Endosperm.

Hensel G, Floss DM, Arcalis E, Sack M, Melnik S, Altmann F, Rutten T, Kumlehn J, Stoger E, Conrad U.

PLoS One. 2015 Oct 13;10(10):e0140476. doi: 10.1371/journal.pone.0140476. eCollection 2015.

21.

From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants.

Sack M, Rademacher T, Spiegel H, Boes A, Hellwig S, Drossard J, Stoger E, Fischer R.

Plant Biotechnol J. 2015 Oct;13(8):1094-105. doi: 10.1111/pbi.12438. Epub 2015 Jul 27.

22.

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.

Ma JK, Drossard J, Lewis D, Altmann F, Boyle J, Christou P, Cole T, Dale P, van Dolleweerd CJ, Isitt V, Katinger D, Lobedan M, Mertens H, Paul MJ, Rademacher T, Sack M, Hundleby PA, Stiegler G, Stoger E, Twyman RM, Vcelar B, Fischer R.

Plant Biotechnol J. 2015 Oct;13(8):1106-20. doi: 10.1111/pbi.12416. Epub 2015 Jul 3.

23.

The molecular basis for development of proinflammatory autoantibodies to progranulin.

Thurner L, Fadle N, Regitz E, Kemele M, Klemm P, Zaks M, Stöger E, Bette B, Carbon G, Zimmer V, Assmann G, Murawski N, Kubuschok B, Held G, Preuss KD, Pfreundschuh M.

J Autoimmun. 2015 Jul;61:17-28. doi: 10.1016/j.jaut.2015.05.002. Epub 2015 May 23.

PMID:
26005049
24.

Rice endosperm produces an underglycosylated and potent form of the HIV-neutralizing monoclonal antibody 2G12.

Vamvaka E, Twyman RM, Murad AM, Melnik S, Teh AY, Arcalis E, Altmann F, Stoger E, Rech E, Ma JK, Christou P, Capell T.

Plant Biotechnol J. 2016 Jan;14(1):97-108. doi: 10.1111/pbi.12360. Epub 2015 Apr 7.

25.

Cell layer-specific distribution of transiently expressed barley ESCRT-III component HvVPS60 in developing barley endosperm.

Hilscher J, Kapusi E, Stoger E, Ibl V.

Protoplasma. 2016 Jan;253(1):137-53. doi: 10.1007/s00709-015-0798-1. Epub 2015 Mar 22.

26.

The increasing value of plant-made proteins.

Sack M, Hofbauer A, Fischer R, Stoger E.

Curr Opin Biotechnol. 2015 Apr;32:163-170. doi: 10.1016/j.copbio.2014.12.008. Epub 2015 Jan 15. Review.

27.

The Induction of Recombinant Protein Bodies in Different Subcellular Compartments Reveals a Cryptic Plastid-Targeting Signal in the 27-kDa γ-Zein Sequence.

Hofbauer A, Peters J, Arcalis E, Rademacher T, Lampel J, Eudes F, Vitale A, Stoger E.

Front Bioeng Biotechnol. 2014 Dec 11;2:67. doi: 10.3389/fbioe.2014.00067. eCollection 2014.

28.

Plant-based solutions for veterinary immunotherapeutics and prophylactics.

Kolotilin I, Topp E, Cox E, Devriendt B, Conrad U, Joensuu J, Stöger E, Warzecha H, McAllister T, Potter A, McLean MD, Hall JC, Menassa R.

Vet Res. 2014 Dec 31;45:117. doi: 10.1186/s13567-014-0117-4. Review.

29.

Characterization of a plant-produced recombinant human secretory IgA with broad neutralizing activity against HIV.

Paul M, Reljic R, Klein K, Drake PM, van Dolleweerd C, Pabst M, Windwarder M, Arcalis E, Stoger E, Altmann F, Cosgrove C, Bartolf A, Baden S, Ma JK.

MAbs. 2014;6(6):1585-97. doi: 10.4161/mabs.36336.

30.

The dynamic behavior of storage organelles in developing cereal seeds and its impact on the production of recombinant proteins.

Arcalis E, Ibl V, Peters J, Melnik S, Stoger E.

Front Plant Sci. 2014 Sep 3;5:439. doi: 10.3389/fpls.2014.00439. eCollection 2014. Review.

31.

[Between empiricism and evidence - ( re ) activation of veterinary phytotherapy].

Walkenhorst M, Vogl CR, Vogl-Lukasser B, Vollstedt S, Brendieck-Worm C, Ivemeyer S, Klarer F, Meier B, Schmid K, Disler M, Bischoff T, Hamburger M, Häsler S, Stöger E.

Forsch Komplementmed. 2014;21 Suppl 1:35-42. doi: 10.1159/000362396. Epub 2014 Jul 4. German. No abstract available.

32.

Influence of elastin-like polypeptide and hydrophobin on recombinant hemagglutinin accumulations in transgenic tobacco plants.

Phan HT, Hause B, Hause G, Arcalis E, Stoger E, Maresch D, Altmann F, Joensuu J, Conrad U.

PLoS One. 2014 Jun 10;9(6):e99347. doi: 10.1371/journal.pone.0099347. eCollection 2014.

33.

Fusion, rupture, and degeneration: the fate of in vivo-labelled PSVs in developing barley endosperm.

Ibl V, Kapusi E, Arcalis E, Kawagoe Y, Stoger E.

J Exp Bot. 2014 Jul;65(12):3249-61. doi: 10.1093/jxb/eru175. Epub 2014 May 6.

34.

Proinflammatory progranulin antibodies in inflammatory bowel diseases.

Thurner L, Stöger E, Fadle N, Klemm P, Regitz E, Kemele M, Bette B, Held G, Dauer M, Lammert F, Preuss KD, Zimmer V, Pfreundschuh M.

Dig Dis Sci. 2014 Aug;59(8):1733-42. doi: 10.1007/s10620-014-3089-3. Epub 2014 Mar 4.

PMID:
24591016
35.

Plant molecular pharming for the treatment of chronic and infectious diseases.

Stoger E, Fischer R, Moloney M, Ma JK.

Annu Rev Plant Biol. 2014;65:743-68. doi: 10.1146/annurev-arplant-050213-035850. Epub 2014 Feb 24. Review.

PMID:
24579993
36.
37.

Aortic valve replacement after previous heart surgery in high-risk patients: transapical aortic valve implantation versus conventional aortic valve replacement-a risk-adjusted and propensity score-based analysis.

Scherner M, Madershahian N, Kuhr K, Rosenkranz S, Stöger E, Rahmanian P, Choi Y, Slottosch I, Wippermann J, Strauch J, Wahlers T.

J Thorac Cardiovasc Surg. 2014 Jul;148(1):90-7. doi: 10.1016/j.jtcvs.2013.07.046. Epub 2013 Oct 11.

38.

Editorial: from plant biotechnology to bio-based products.

Stöger E.

Biotechnol J. 2013 Oct;8(10):1122-3. doi: 10.1002/biot.201300392.

PMID:
24092669
39.

Efficient recovery of recombinant proteins from cereal endosperm is affected by interaction with endogenous storage proteins.

Peters J, Sabalza M, Ramessar K, Christou P, Capell T, Stöger E, Arcalís E.

Biotechnol J. 2013 Oct;8(10):1203-12. doi: 10.1002/biot.201300068. Epub 2013 Sep 17.

PMID:
23960004
40.

Plant species and organ influence the structure and subcellular localization of recombinant glycoproteins.

Arcalis E, Stadlmann J, Rademacher T, Marcel S, Sack M, Altmann F, Stoger E.

Plant Mol Biol. 2013 Sep;83(1-2):105-17. doi: 10.1007/s11103-013-0049-9. Epub 2013 Apr 4.

PMID:
23553222
41.

Subcellular accumulation and modification of pharmaceutical proteins in different plant tissues.

Hofbauer A, Stoger E.

Curr Pharm Des. 2013;19(31):5495-502. Review.

PMID:
23394560
42.

Green factories for biopharmaceuticals.

Melnik S, Stoger E.

Curr Med Chem. 2013;20(8):1038-46. Review.

PMID:
23210788
43.

Using storage organelles for the accumulation and encapsulation of recombinant proteins.

Khan I, Twyman RM, Arcalis E, Stoger E.

Biotechnol J. 2012 Sep;7(9):1099-108. doi: 10.1002/biot.201100089. Epub 2012 Mar 7. Review.

PMID:
22396218
44.

Plant bioreactors - the taste of sweet success.

Stoger E.

Biotechnol J. 2012 Apr;7(4):475-6. doi: 10.1002/biot.201100472. Epub 2012 Jan 18.

PMID:
22253253
45.

Predominant localization of the major Alternaria allergen Alt a 1 in the cell wall of airborne spores.

Twaroch TE, Arcalís E, Sterflinger K, Stöger E, Swoboda I, Valenta R.

J Allergy Clin Immunol. 2012 Apr;129(4):1148-9. doi: 10.1016/j.jaci.2011.10.008. Epub 2011 Nov 12. No abstract available.

PMID:
22078468
46.

The formation, function and fate of protein storage compartments in seeds.

Ibl V, Stoger E.

Protoplasma. 2012 Apr;249(2):379-92. doi: 10.1007/s00709-011-0288-z. Epub 2011 May 26.

PMID:
21614590
47.

Non-food/feed seeds as biofactories for the high-yield production of recombinant pharmaceuticals.

Morandini F, Avesani L, Bortesi L, Van Droogenbroeck B, De Wilde K, Arcalis E, Bazzoni F, Santi L, Brozzetti A, Falorni A, Stoger E, Depicker A, Pezzotti M.

Plant Biotechnol J. 2011 Oct;9(8):911-21. doi: 10.1111/j.1467-7652.2011.00605.x. Epub 2011 Apr 11.

48.

Transgenic crops for the production of recombinant vaccines and anti-microbial antibodies.

Peters J, Stoger E.

Hum Vaccin. 2011 Mar;7(3):367-74. Epub 2011 Mar 1. Review.

PMID:
21346415
49.

Cloning and characterization of purple acid phosphatase phytases from wheat, barley, maize, and rice.

Dionisio G, Madsen CK, Holm PB, Welinder KG, Jørgensen M, Stoger E, Arcalis E, Brinch-Pedersen H.

Plant Physiol. 2011 Jul;156(3):1087-100. doi: 10.1104/pp.110.164756. Epub 2011 Jan 10.

50.

The changing fate of a secretory glycoprotein in developing maize endosperm.

Arcalis E, Stadlmann J, Marcel S, Drakakaki G, Winter V, Rodriguez J, Fischer R, Altmann F, Stoger E.

Plant Physiol. 2010 Jun;153(2):693-702. doi: 10.1104/pp.109.152363. Epub 2010 Apr 13.

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