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Diagnostic impact of additional O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET following immunotherapy with dendritic cell vaccination in glioblastoma patients.

Kristin Schmitz A, Sorg RV, Stoffels G, Grauer OM, Galldiks N, Steiger HJ, Kamp MA, Langen KJ, Sabel M, Rapp M.

Br J Neurosurg. 2019 Aug 13:1-7. doi: 10.1080/02688697.2019.1639615. [Epub ahead of print]


Differentiation of treatment-related changes from tumour progression: a direct comparison between dynamic FET PET and ADC values obtained from DWI MRI.

Werner JM, Stoffels G, Lichtenstein T, Borggrefe J, Lohmann P, Ceccon G, Shah NJ, Fink GR, Langen KJ, Kabbasch C, Galldiks N.

Eur J Nucl Med Mol Imaging. 2019 Aug;46(9):1889-1901. doi: 10.1007/s00259-019-04384-7. Epub 2019 Jun 15.


Management of vaso-occlusive episodes in the day hospital decreases admissions in children with sickle cell disease.

Karkoska K, Appiah-Kubi A, Rocker J, Stoffels G, Aygun B.

Br J Haematol. 2019 May 31. doi: 10.1111/bjh.16002. [Epub ahead of print]


Photopenic defects on O-(2-[18F]-fluoroethyl)-L-tyrosine PET - Clinical relevance in glioma patients.

Galldiks N, Unterrainer M, Judov N, Stoffels G, Rapp M, Lohmann P, Vettermann F, Dunkl V, Suchorska B, Tonn JC, Kreth FW, Fink GR, Bartenstein P, Langen KJ, Albert NL.

Neuro Oncol. 2019 May 11. pii: noz083. doi: 10.1093/neuonc/noz083. [Epub ahead of print]


Comparison of [18F]Fluoroethyltyrosine PET and Sodium MRI in Cerebral Gliomas: a Pilot Study.

Shymanskaya A, Worthoff WA, Stoffels G, Lindemeyer J, Neumaier B, Lohmann P, Galldiks N, Langen KJ, Shah NJ.

Mol Imaging Biol. 2019 Apr 15. doi: 10.1007/s11307-019-01349-y. [Epub ahead of print]


Cis-4-[18F]fluoro-D-proline detects neurodegeneration in patients with akinetic-rigid parkinsonism.

Sommerauer M, Galldiks N, Barbe MT, Stoffels G, Willuweit A, Coenen HH, Schroeter M, Timmermann L, Fink GR, Langen KJ.

Nucl Med Commun. 2019 Apr;40(4):383-387. doi: 10.1097/MNM.0000000000000982.


Treatment-related uptake of O-(2-[18F]fluoroethyl)-L-tyrosine and L-[methyl-3H]-methionine after tumor resection in rat glioma models.

Geisler S, Stegmayr C, Niemietz N, Lohmann P, Rapp M, Stoffels G, Willuweit A, Galldiks N, Filss CP, Sabel M, Coenen HH, Shah NJ, Langen KJ.

J Nucl Med. 2019 Mar 8. pii: jnumed.119.225680. doi: 10.2967/jnumed.119.225680. [Epub ahead of print]


Long-term Visual Outcomes and Causes of Vision Loss in Chronic Central Serous Chorioretinopathy.

Mrejen S, Balaratnasingam C, Kaden TR, Bottini A, Dansingani K, Bhavsar KV, Yannuzzi NA, Patel S, Chen KC, Yu S, Stoffels G, Spaide RF, Freund KB, Yannuzzi LA.

Ophthalmology. 2019 Apr;126(4):576-588. doi: 10.1016/j.ophtha.2018.12.048. Epub 2019 Jan 17.


Increasing Pediatricians' Awareness of the Association between Anal Skin Tags and Earlier Diagnosis of Crohn's Disease.

Korelitz BI, Partiula B, Teagle K, Swaminath A, Schneider J, Ellington M, Stoffels G.

Inflamm Intest Dis. 2018 Nov;3(1):40-42. doi: 10.1159/000492921. Epub 2018 Oct 4.


Examining the Utility of Coronary Artery Lack of Tapering and Perivascular Brightness in Incomplete Kawasaki Disease.

Rabinowitz EJ, Rubin LG, Desai K, Hayes DA, Tugertimur A, Kwon EN, Dhanantwari P, Misra N, Stoffels G, Blaufox AD, Mitchell E.

Pediatr Cardiol. 2019 Jan;40(1):147-153. doi: 10.1007/s00246-018-1971-z. Epub 2018 Sep 8.


Predicting IDH genotype in gliomas using FET PET radiomics.

Lohmann P, Lerche C, Bauer EK, Steger J, Stoffels G, Blau T, Dunkl V, Kocher M, Viswanathan S, Filss CP, Stegmayr C, Ruge MI, Neumaier B, Shah NJ, Fink GR, Langen KJ, Galldiks N.

Sci Rep. 2018 Sep 6;8(1):13328. doi: 10.1038/s41598-018-31806-7.


Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis.

Lohmann P, Kocher M, Ceccon G, Bauer EK, Stoffels G, Viswanathan S, Ruge MI, Neumaier B, Shah NJ, Fink GR, Langen KJ, Galldiks N.

Neuroimage Clin. 2018 Aug 19;20:537-542. doi: 10.1016/j.nicl.2018.08.024. eCollection 2018.


Early treatment response evaluation using FET PET compared to MRI in glioblastoma patients at first progression treated with bevacizumab plus lomustine.

Galldiks N, Dunkl V, Ceccon G, Tscherpel C, Stoffels G, Law I, Henriksen OM, Muhic A, Poulsen HS, Steger J, Bauer EK, Lohmann P, Schmidt M, Shah NJ, Fink GR, Langen KJ.

Eur J Nucl Med Mol Imaging. 2018 Dec;45(13):2377-2386. doi: 10.1007/s00259-018-4082-4. Epub 2018 Jul 7.


Management of iatrogenic perforation during colonoscopy in ulcerative colitis patients: a survey of gastroenterologists and colorectal surgeons.

DiCaprio D, Lee-Kong S, Stoffels G, Shen B, Al-Mazrou A, Kiran RP, Korelitz B, Swaminath A.

Int J Colorectal Dis. 2018 Nov;33(11):1607-1616. doi: 10.1007/s00384-018-3112-9. Epub 2018 Jul 5.


Influence of Dexamethasone on O-(2-[18F]-Fluoroethyl)-L-Tyrosine Uptake in the Human Brain and Quantification of Tumor Uptake.

Stegmayr C, Stoffels G, Kops ER, Lohmann P, Galldiks N, Shah NJ, Neumaier B, Langen KJ.

Mol Imaging Biol. 2019 Feb;21(1):168-174. doi: 10.1007/s11307-018-1221-z.


Prevalence of Proteinuria and Albuminuria in an Obese Population and Associated Risk Factors.

Rosenstock JL, Pommier M, Stoffels G, Patel S, Michelis MF.

Front Med (Lausanne). 2018 Apr 30;5:122. doi: 10.3389/fmed.2018.00122. eCollection 2018.


Investigation of cis-4-[18F]Fluoro-D-Proline Uptake in Human Brain Tumors After Multimodal Treatment.

Verger A, Stoffels G, Galldiks N, Lohmann P, Willuweit A, Neumaier B, Geisler S, Langen KJ.

Mol Imaging Biol. 2018 Dec;20(6):1035-1043. doi: 10.1007/s11307-018-1197-8.


Dabrafenib Treatment in a Patient with an Epithelioid Glioblastoma and BRAF V600E Mutation.

Ceccon G, Werner JM, Dunkl V, Tscherpel C, Stoffels G, Brunn A, Deckert M, Fink GR, Galldiks N.

Int J Mol Sci. 2018 Apr 5;19(4). pii: E1090. doi: 10.3390/ijms19041090.


Use of FET PET in glioblastoma patients undergoing neurooncological treatment including tumour-treating fields: initial experience.

Ceccon G, Lazaridis L, Stoffels G, Rapp M, Weber M, Blau T, Lohmann P, Kebir S, Herrmann K, Fink GR, Langen KJ, Glas M, Galldiks N.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(9):1626-1635. doi: 10.1007/s00259-018-3992-5. Epub 2018 Mar 21.


Comparison of O-(2-18F-Fluoroethyl)-L-Tyrosine Positron Emission Tomography and Perfusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Patients with Progressive and Recurrent Glioma: A Hybrid Positron Emission Tomography/Magnetic Resonance Study.

Verger A, Filss CP, Lohmann P, Stoffels G, Sabel M, Wittsack HJ, Kops ER, Galldiks N, Fink GR, Shah NJ, Langen KJ.

World Neurosurg. 2018 May;113:e727-e737. doi: 10.1016/j.wneu.2018.02.139. Epub 2018 Mar 3.


Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI.

da Silva NA, Lohmann P, Fairney J, Magill AW, Oros Peusquens AM, Choi CH, Stirnberg R, Stoffels G, Galldiks N, Golay X, Langen KJ, Jon Shah N.

Eur J Nucl Med Mol Imaging. 2018 Jun;45(6):1031-1040. doi: 10.1007/s00259-018-3940-4. Epub 2018 Feb 24.


Evaluation of factors influencing 18F-FET uptake in the brain.

Verger A, Stegmayr C, Galldiks N, Van Der Gucht A, Lohmann P, Stoffels G, Shah NJ, Fink GR, Eickhoff SB, Guedj E, Langen KJ.

Neuroimage Clin. 2017 Nov 8;17:491-497. doi: 10.1016/j.nicl.2017.11.005. eCollection 2018.


Outcomes of thoracic endovascular aortic repair for chronic aortic dissections.

Conway AM, Qato K, Mondry LR, Stoffels GJ, Giangola G, Carroccio A.

J Vasc Surg. 2018 May;67(5):1345-1352. doi: 10.1016/j.jvs.2017.08.098. Epub 2017 Nov 20.


Static and dynamic 18F-FET PET for the characterization of gliomas defined by IDH and 1p/19q status.

Verger A, Stoffels G, Bauer EK, Lohmann P, Blau T, Fink GR, Neumaier B, Shah NJ, Langen KJ, Galldiks N.

Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):443-451. doi: 10.1007/s00259-017-3846-6. Epub 2017 Oct 17.


Dabrafenib in patients with recurrent, BRAF V600E mutated malignant glioma and leptomeningeal disease.

Burger MC, Ronellenfitsch MW, Lorenz NI, Wagner M, Voss M, Capper D, Tzaridis T, Herrlinger U, Steinbach JP, Stoffels G, Langen KJ, Brandts C, Senft C, Harter PN, Bähr O.

Oncol Rep. 2017 Dec;38(6):3291-3296. doi: 10.3892/or.2017.6013. Epub 2017 Oct 2.


Fine-needle aspiration biopsy of lytic bone lesions: An institution's experience.

Shergill U, Vitkovski T, Stoffels G, Klein M, Gimenez C, Laser A, Cocker R, Chau K, Das K.

Diagn Cytopathol. 2017 Nov;45(11):989-997. doi: 10.1002/dc.23807. Epub 2017 Sep 1.


Spatial Relationship of Glioma Volume Derived from 18F-FET PET and Volumetric MR Spectroscopy Imaging: A Hybrid PET/MRI Study.

Mauler J, Maudsley AA, Langen KJ, Nikoubashman O, Stoffels G, Sheriff S, Lohmann P, Filss C, Galldiks N, Kops ER, Shah NJ.

J Nucl Med. 2018 Apr;59(4):603-609. doi: 10.2967/jnumed.117.196709. Epub 2017 Aug 28.


Comparison of 18F-FET PET and perfusion-weighted MRI for glioma grading: a hybrid PET/MR study.

Verger A, Filss CP, Lohmann P, Stoffels G, Sabel M, Wittsack HJ, Kops ER, Galldiks N, Fink GR, Shah NJ, Langen KJ.

Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2257-2265. doi: 10.1007/s00259-017-3812-3. Epub 2017 Aug 22.


O-(2-[18F]fluoroethyl)-L-tyrosine PET in gliomas: influence of data processing in different centres.

Filss CP, Albert NL, Böning G, Kops ER, Suchorska B, Stoffels G, Galldiks N, Shah NJ, Mottaghy FM, Bartenstein P, Tonn JC, Langen KJ.

EJNMMI Res. 2017 Aug 16;7(1):64. doi: 10.1186/s13550-017-0316-x.


Imaging of amino acid transport in brain tumours: Positron emission tomography with O-(2-[18F]fluoroethyl)-L-tyrosine (FET).

Langen KJ, Stoffels G, Filss C, Heinzel A, Stegmayr C, Lohmann P, Willuweit A, Neumaier B, Mottaghy FM, Galldiks N.

Methods. 2017 Nov 1;130:124-134. doi: 10.1016/j.ymeth.2017.05.019. Epub 2017 May 24. Review.


Subclinical Decrease in Myocardial Function in Asymptomatic Infants of Diabetic Mothers: A Tissue Doppler Study.

Zablah JE, Gruber D, Stoffels G, Cabezas EG, Hayes DA.

Pediatr Cardiol. 2017 Apr;38(4):801-806. doi: 10.1007/s00246-017-1584-y. Epub 2017 Feb 14.


Functional MRI vs. navigated TMS to optimize M1 seed volume delineation for DTI tractography. A prospective study in patients with brain tumours adjacent to the corticospinal tract.

Weiss Lucas C, Tursunova I, Neuschmelting V, Nettekoven C, Oros-Peusquens AM, Stoffels G, Faymonville AM, Jon SN, Langen KJ, Lockau H, Goldbrunner R, Grefkes C.

Neuroimage Clin. 2016 Nov 23;13:297-309. doi: 10.1016/j.nicl.2016.11.022. eCollection 2017.


The use of O-(2-18F-fluoroethyl)-L-tyrosine PET in the diagnosis of gliomas located in the brainstem and spinal cord.

Tscherpel C, Dunkl V, Ceccon G, Stoffels G, Judov N, Rapp M, Meyer PT, Kops ER, Ermert J, Fink GR, Shah NJ, Langen KJ, Galldiks N.

Neuro Oncol. 2017 May 1;19(5):710-718. doi: 10.1093/neuonc/now243.


Radiation injury vs. recurrent brain metastasis: combining textural feature radiomics analysis and standard parameters may increase 18F-FET PET accuracy without dynamic scans.

Lohmann P, Stoffels G, Ceccon G, Rapp M, Sabel M, Filss CP, Kamp MA, Stegmayr C, Neumaier B, Shah NJ, Langen KJ, Galldiks N.

Eur Radiol. 2017 Jul;27(7):2916-2927. doi: 10.1007/s00330-016-4638-2. Epub 2016 Nov 16.


Dynamic O-(2-18F-fluoroethyl)-L-tyrosine positron emission tomography differentiates brain metastasis recurrence from radiation injury after radiotherapy.

Ceccon G, Lohmann P, Stoffels G, Judov N, Filss CP, Rapp M, Bauer E, Hamisch C, Ruge MI, Kocher M, Kuchelmeister K, Sellhaus B, Sabel M, Fink GR, Shah NJ, Langen KJ, Galldiks N.

Neuro Oncol. 2017 Feb 1;19(2):281-288. doi: 10.1093/neuonc/now149.


Relapse patterns after radiochemotherapy of glioblastoma with FET PET-guided boost irradiation and simulation to optimize radiation target volume.

Piroth MD, Galldiks N, Pinkawa M, Holy R, Stoffels G, Ermert J, Mottaghy FM, Shah NJ, Langen KJ, Eble MJ.

Radiat Oncol. 2016 Jun 24;11:87. doi: 10.1186/s13014-016-0665-z.


Congruency of tumour volume delineated by FET PET and MRSI.

Mauler J, Langen KJ, Maudsley AA, Nikoubashman O, Filss C, Stoffels G, Shah NJ.

EJNMMI Phys. 2015 Dec;2(Suppl 1):A61. doi: 10.1186/2197-7364-2-S1-A61. No abstract available.


Late Pseudoprogression in Glioblastoma: Diagnostic Value of Dynamic O-(2-[18F]fluoroethyl)-L-Tyrosine PET.

Kebir S, Fimmers R, Galldiks N, Schäfer N, Mack F, Schaub C, Stuplich M, Niessen M, Tzaridis T, Simon M, Stoffels G, Langen KJ, Scheffler B, Glas M, Herrlinger U.

Clin Cancer Res. 2016 May 1;22(9):2190-6. doi: 10.1158/1078-0432.CCR-15-1334. Epub 2015 Dec 16.


Multimodal Imaging in Malignant Brain Tumors: Enhancing the Preoperative Risk Evaluation for Motor Deficits with a Combined Hybrid MRI-PET and Navigated Transcranial Magnetic Stimulation Approach.

Neuschmelting V, Weiss Lucas C, Stoffels G, Oros-Peusquens AM, Lockau H, Shah NJ, Langen KJ, Goldbrunner R, Grefkes C.

AJNR Am J Neuroradiol. 2016 Feb;37(2):266-73. doi: 10.3174/ajnr.A4536. Epub 2015 Oct 29.


The use of dynamic O-(2-18F-fluoroethyl)-l-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma.

Galldiks N, Stoffels G, Filss C, Rapp M, Blau T, Tscherpel C, Ceccon G, Dunkl V, Weinzierl M, Stoffel M, Sabel M, Fink GR, Shah NJ, Langen KJ.

Neuro Oncol. 2015 Sep;17(9):1293-300. doi: 10.1093/neuonc/nov088. Epub 2015 May 24.


Increasing RO efficiency by chemical-free ion-exchange and Donnan dialysis: Principles and practical implications.

Vanoppen M, Stoffels G, Demuytere C, Bleyaert W, Verliefde AR.

Water Res. 2015 Sep 1;80:59-70. doi: 10.1016/j.watres.2015.04.030. Epub 2015 May 8.


Dual-time-point O-(2-[(18)F]fluoroethyl)-L-tyrosine PET for grading of cerebral gliomas.

Lohmann P, Herzog H, Rota Kops E, Stoffels G, Judov N, Filss C, Galldiks N, Tellmann L, Weiss C, Sabel M, Coenen HH, Shah NJ, Langen KJ.

Eur Radiol. 2015 Oct;25(10):3017-24. doi: 10.1007/s00330-015-3691-6. Epub 2015 Mar 27.


Improved nTMS- and DTI-derived CST tractography through anatomical ROI seeding on anterior pontine level compared to internal capsule.

Weiss C, Tursunova I, Neuschmelting V, Lockau H, Nettekoven C, Oros-Peusquens AM, Stoffels G, Rehme AK, Faymonville AM, Shah NJ, Langen KJ, Goldbrunner R, Grefkes C.

Neuroimage Clin. 2015 Jan 20;7:424-37. doi: 10.1016/j.nicl.2015.01.006. eCollection 2015.


The usefulness of dynamic O-(2-18F-fluoroethyl)-L-tyrosine PET in the clinical evaluation of brain tumors in children and adolescents.

Dunkl V, Cleff C, Stoffels G, Judov N, Sarikaya-Seiwert S, Law I, Bøgeskov L, Nysom K, Andersen SB, Steiger HJ, Fink GR, Reifenberger G, Shah NJ, Coenen HH, Langen KJ, Galldiks N.

J Nucl Med. 2015 Jan;56(1):88-92. doi: 10.2967/jnumed.114.148734. Epub 2014 Dec 18.


Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET.

Galldiks N, Dunkl V, Stoffels G, Hutterer M, Rapp M, Sabel M, Reifenberger G, Kebir S, Dorn F, Blau T, Herrlinger U, Hau P, Ruge MI, Kocher M, Goldbrunner R, Fink GR, Drzezga A, Schmidt M, Langen KJ.

Eur J Nucl Med Mol Imaging. 2015 Apr;42(5):685-95. doi: 10.1007/s00259-014-2959-4. Epub 2014 Nov 20.


Uptake and tracer kinetics of O-(2-(18)F-fluoroethyl)-L-tyrosine in meningiomas: preliminary results.

Cornelius JF, Stoffels G, Filß C, Galldiks N, Slotty P, Kamp M, el Khatib M, Hänggi D, Sabel M, Felsberg J, Steiger HJ, Coenen HH, Shah NJ, Langen KJ.

Eur J Nucl Med Mol Imaging. 2015 Mar;42(3):459-67. doi: 10.1007/s00259-014-2934-0. Epub 2014 Oct 21.


Isomers of 4-[18F]fluoro-proline: radiosynthesis, biological evaluation and results in humans using PET.

Geisler S, Ermert J, Stoffels G, Willuweit A, Galldiks N, Filss CP, Shah NJ, Coenen HH, Langen KJ.

Curr Radiopharm. 2014;7(2):123-32. Review.


Adapting MR-BrainPET scans for comparison with conventional PET: experiences with dynamic FET-PET in brain tumours.

Lohmann P, Herzog H, Kops ER, Stoffels G, Filss C, Galldiks N, Coenen HH, Shah NJ, Langen KJ.

EJNMMI Phys. 2014 Jul;1(Suppl 1):A64. doi: 10.1186/2197-7364-1-S1-A64. No abstract available.


Blind source separation analysis of PET dynamic data: a simple method with exciting MR-PET applications.

Oros-Peusquens AM, da Silva N, Weiss C, Stoffels G, Herzog H, Langen KJ, Shah NJ.

EJNMMI Phys. 2014 Jul;1(Suppl 1):A28. doi: 10.1186/2197-7364-1-S1-A28. No abstract available.


Comparison of 18F-FET PET and perfusion-weighted MR imaging: a PET/MR imaging hybrid study in patients with brain tumors.

Filss CP, Galldiks N, Stoffels G, Sabel M, Wittsack HJ, Turowski B, Antoch G, Zhang K, Fink GR, Coenen HH, Shah NJ, Herzog H, Langen KJ.

J Nucl Med. 2014 Apr;55(4):540-5. doi: 10.2967/jnumed.113.129007. Epub 2014 Feb 27.

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