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Items: 1 to 50 of 62

1.

TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress.

Lafarga V, Sung HM, Haneke K, Roessig L, Pauleau AL, Bruer M, Rodriguez-Acebes S, Lopez-Contreras AJ, Gruss OJ, Erhardt S, Mendez J, Fernandez-Capetillo O, Stoecklin G.

EMBO Rep. 2019 Jan;20(1). pii: e46224. doi: 10.15252/embr.201846224. Epub 2018 Dec 11.

2.

A signal to condense.

Ruggieri A, Stoecklin G.

Nat Chem Biol. 2019 Jan;15(1):5-6. doi: 10.1038/s41589-018-0179-0. No abstract available.

PMID:
30531906
3.

Erratum: DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Oct 27;49(11):1661. doi: 10.1038/ng1117-1661c.

PMID:
29074949
4.

CBP-mediated SMN acetylation modulates Cajal body biogenesis and the cytoplasmic targeting of SMN.

Lafarga V, Tapia O, Sharma S, Bengoechea R, Stoecklin G, Lafarga M, Berciano MT.

Cell Mol Life Sci. 2018 Feb;75(3):527-546. doi: 10.1007/s00018-017-2638-2. Epub 2017 Sep 6.

PMID:
28879433
5.

Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes.

Vindry C, Marnef A, Broomhead H, Twyffels L, Ozgur S, Stoecklin G, Llorian M, Smith CW, Mata J, Weil D, Standart N.

Cell Rep. 2017 Aug 1;20(5):1187-1200. doi: 10.1016/j.celrep.2017.06.091.

6.

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

Brocks D, Schmidt CR, Daskalakis M, Jang HS, Shah NM, Li D, Li J, Zhang B, Hou Y, Laudato S, Lipka DB, Schott J, Bierhoff H, Assenov Y, Helf M, Ressnerova A, Islam MS, Lindroth AM, Haas S, Essers M, Imbusch CD, Brors B, Oehme I, Witt O, Lübbert M, Mallm JP, Rippe K, Will R, Weichenhan D, Stoecklin G, Gerhäuser C, Oakes CC, Wang T, Plass C.

Nat Genet. 2017 Jul;49(7):1052-1060. doi: 10.1038/ng.3889. Epub 2017 Jun 12. Erratum in: Nat Genet. 2017 Oct 27;49(11):1661.

7.

Erratum for Roth et al., "Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses".

Roth H, Magg V, Uch F, Mutz P, Klein P, Haneke K, Lohmann V, Bartenschlager R, Fackler OT, Locker N, Stoecklin G, Ruggieri A.

MBio. 2017 Apr 18;8(2). pii: e00488-17. doi: 10.1128/mBio.00488-17. No abstract available.

8.

Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses.

Roth H, Magg V, Uch F, Mutz P, Klein P, Haneke K, Lohmann V, Bartenschlager R, Fackler OT, Locker N, Stoecklin G, Ruggieri A.

MBio. 2017 Jan 10;8(1). pii: e02150-16. doi: 10.1128/mBio.02150-16. Erratum in: MBio. 2017 Apr 18;8(2):.

9.

Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2.

Sharma S, Poetz F, Bruer M, Ly-Hartig TB, Schott J, Séraphin B, Stoecklin G.

Mol Cell. 2016 Sep 15;63(6):927-38. doi: 10.1016/j.molcel.2016.08.030.

10.

Systemic control of protein synthesis through sequestration of translation and ribosome biogenesis factors during severe heat stress.

Cherkasov V, Grousl T, Theer P, Vainshtein Y, Glässer C, Mongis C, Kramer G, Stoecklin G, Knop M, Mogk A, Bukau B.

FEBS Lett. 2015 Nov 30;589(23):3654-64. doi: 10.1016/j.febslet.2015.10.010. Epub 2015 Oct 17.

11.

The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis.

Tuorto F, Herbst F, Alerasool N, Bender S, Popp O, Federico G, Reitter S, Liebers R, Stoecklin G, Gröne HJ, Dittmar G, Glimm H, Lyko F.

EMBO J. 2015 Sep 14;34(18):2350-62. doi: 10.15252/embj.201591382. Epub 2015 Aug 13.

12.

A Distinct, Sequence-Induced Conformation Is Required for Recognition of the Constitutive Decay Element RNA by Roquin.

Codutti L, Leppek K, Zálešák J, Windeisen V, Masiewicz P, Stoecklin G, Carlomagno T.

Structure. 2015 Aug 4;23(8):1437-1447. doi: 10.1016/j.str.2015.06.001. Epub 2015 Jul 9.

13.

Plakophilins 1 and 3 bind to FXR1 and thereby influence the mRNA stability of desmosomal proteins.

Fischer-Kešo R, Breuninger S, Hofmann S, Henn M, Röhrig T, Ströbel P, Stoecklin G, Hofmann I.

Mol Cell Biol. 2014 Dec 1;34(23):4244-56. doi: 10.1128/MCB.00766-14. Epub 2014 Sep 15.

14.

tRNAs: new tricks from old dogs.

Stoecklin G, Diederichs S.

EMBO J. 2014 Sep 17;33(18):1981-3. doi: 10.15252/embj.201489634. Epub 2014 Sep 12.

15.

DENR-MCT-1 promotes translation re-initiation downstream of uORFs to control tissue growth.

Schleich S, Strassburger K, Janiesch PC, Koledachkina T, Miller KK, Haneke K, Cheng YS, Kuechler K, Stoecklin G, Duncan KE, Teleman AA.

Nature. 2014 Aug 14;512(7513):208-212. doi: 10.1038/nature13401. Epub 2014 Jul 6.

16.

Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation.

Schott J, Reitter S, Philipp J, Haneke K, Schäfer H, Stoecklin G.

PLoS Genet. 2014 Jun 19;10(6):e1004368. doi: 10.1371/journal.pgen.1004368. eCollection 2014 Jun.

17.

Coordination of translational control and protein homeostasis during severe heat stress.

Cherkasov V, Hofmann S, Druffel-Augustin S, Mogk A, Tyedmers J, Stoecklin G, Bukau B.

Curr Biol. 2013 Dec 16;23(24):2452-62. doi: 10.1016/j.cub.2013.09.058. Epub 2013 Nov 27.

18.

Telling right from wrong in life - cellular quality control.

Stoecklin G, Bukau B.

Nat Rev Mol Cell Biol. 2013 Oct;14(10):613-5. doi: 10.1038/nrm3662.

PMID:
24199228
19.

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins.

Leppek K, Stoecklin G.

Nucleic Acids Res. 2014 Jan;42(2):e13. doi: 10.1093/nar/gkt956. Epub 2013 Oct 23.

20.

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

Hämmerle M, Gutschner T, Uckelmann H, Ozgur S, Fiskin E, Gross M, Skawran B, Geffers R, Longerich T, Breuhahn K, Schirmacher P, Stoecklin G, Diederichs S.

Hepatology. 2013 Nov;58(5):1703-12. doi: 10.1002/hep.26537. Epub 2013 Aug 7.

PMID:
23728852
21.

Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs.

Leppek K, Schott J, Reitter S, Poetz F, Hammond MC, Stoecklin G.

Cell. 2013 May 9;153(4):869-81. doi: 10.1016/j.cell.2013.04.016.

22.

RNA decay mechanisms: specificity through diversity.

Stoecklin G, Mühlemann O.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):487-90. doi: 10.1016/j.bbagrm.2013.04.002. Epub 2013 Apr 10. No abstract available.

PMID:
23583720
23.

Role of Rck-Pat1b binding in assembly of processing-bodies.

Ozgur S, Stoecklin G.

RNA Biol. 2013 Apr;10(4):528-39. doi: 10.4161/rna.24086. Epub 2013 Mar 27.

24.

Relationship of GW/P-bodies with stress granules.

Stoecklin G, Kedersha N.

Adv Exp Med Biol. 2013;768:197-211. doi: 10.1007/978-1-4614-5107-5_12. Review.

25.

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs.

Färber V, Erben E, Sharma S, Stoecklin G, Clayton C.

Nucleic Acids Res. 2013 Jan;41(2):1211-22. doi: 10.1093/nar/gks1133. Epub 2012 Dec 4.

26.

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

Tuorto F, Liebers R, Musch T, Schaefer M, Hofmann S, Kellner S, Frye M, Helm M, Stoecklin G, Lyko F.

Nat Struct Mol Biol. 2012 Sep;19(9):900-5. doi: 10.1038/nsmb.2357. Epub 2012 Aug 12.

PMID:
22885326
27.

Translation suppression promotes stress granule formation and cell survival in response to cold shock.

Hofmann S, Cherkasova V, Bankhead P, Bukau B, Stoecklin G.

Mol Biol Cell. 2012 Oct;23(19):3786-800. doi: 10.1091/mbc.E12-04-0296. Epub 2012 Aug 8.

28.

Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection.

Ruggieri A, Dazert E, Metz P, Hofmann S, Bergeest JP, Mazur J, Bankhead P, Hiet MS, Kallis S, Alvisi G, Samuel CE, Lohmann V, Kaderali L, Rohr K, Frese M, Stoecklin G, Bartenschlager R.

Cell Host Microbe. 2012 Jul 19;12(1):71-85. doi: 10.1016/j.chom.2012.05.013.

29.

AU-rich element-mediated mRNA decay can occur independently of the miRNA machinery in mouse embryonic fibroblasts and Drosophila S2-cells.

Helfer S, Schott J, Stoecklin G, Förstemann K.

PLoS One. 2012;7(1):e28907. doi: 10.1371/journal.pone.0028907. Epub 2012 Jan 13.

30.

Genome-wide assessment of AU-rich elements by the AREScore algorithm.

Spasic M, Friedel CC, Schott J, Kreth J, Leppek K, Hofmann S, Ozgur S, Stoecklin G.

PLoS Genet. 2012 Jan;8(1):e1002433. doi: 10.1371/journal.pgen.1002433. Epub 2012 Jan 5.

31.

Protein synthesis and translational control: at eye level with the ribosome.

Leppek K, Schott J, Stoecklin G.

EMBO Rep. 2011 Dec 1;12(12):1214-6. doi: 10.1038/embor.2011.224.

32.

Networks controlling mRNA decay in the immune system.

Schott J, Stoecklin G.

Wiley Interdiscip Rev RNA. 2010 Nov-Dec;1(3):432-56. doi: 10.1002/wrna.13. Review.

PMID:
21956941
33.

Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin.

Sandler H, Kreth J, Timmers HT, Stoecklin G.

Nucleic Acids Res. 2011 May;39(10):4373-86. doi: 10.1093/nar/gkr011. Epub 2011 Jan 29.

34.

Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.

Clement SL, Scheckel C, Stoecklin G, Lykke-Andersen J.

Mol Cell Biol. 2011 Jan;31(2):256-66. doi: 10.1128/MCB.00717-10. Epub 2010 Nov 15.

35.

Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies.

Ozgur S, Chekulaeva M, Stoecklin G.

Mol Cell Biol. 2010 Sep;30(17):4308-23. doi: 10.1128/MCB.00429-10. Epub 2010 Jun 28.

36.

On track with P-bodies.

Kulkarni M, Ozgur S, Stoecklin G.

Biochem Soc Trans. 2010 Feb;38(Pt 1):242-51. doi: 10.1042/BST0380242. Review.

PMID:
20074068
37.

Control of mRNA decay by phosphorylation of tristetraprolin.

Sandler H, Stoecklin G.

Biochem Soc Trans. 2008 Jun;36(Pt 3):491-6. doi: 10.1042/BST0360491. Review.

PMID:
18481987
38.

A role for Caf1 in mRNA deadenylation and decay in trypanosomes and human cells.

Schwede A, Ellis L, Luther J, Carrington M, Stoecklin G, Clayton C.

Nucleic Acids Res. 2008 Jun;36(10):3374-88. doi: 10.1093/nar/gkn108. Epub 2008 Apr 27.

39.

Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin.

Stoecklin G, Tenenbaum SA, Mayo T, Chittur SV, George AD, Baroni TE, Blackshear PJ, Anderson P.

J Biol Chem. 2008 Apr 25;283(17):11689-99. doi: 10.1074/jbc.M709657200. Epub 2008 Feb 6.

40.

T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs.

Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P.

J Biol Chem. 2007 Oct 12;282(41):30070-7. Epub 2007 Aug 21.

41.

In a tight spot: ARE-mRNAs at processing bodies.

Stoecklin G, Anderson P.

Genes Dev. 2007 Mar 15;21(6):627-31. Review. No abstract available.

42.

A GFP-based assay for monitoring post-transcriptional regulation of ARE-mRNA turnover.

Benjamin D, Colombi M, Stoecklin G, Moroni C.

Mol Biosyst. 2006 Nov;2(11):561-7. Epub 2006 Sep 27.

PMID:
17216037
43.

Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNA.

Sun L, Stoecklin G, Van Way S, Hinkovska-Galcheva V, Guo RF, Anderson P, Shanley TP.

J Biol Chem. 2007 Feb 9;282(6):3766-77. Epub 2006 Dec 14.

44.

Posttranscriptional mechanisms regulating the inflammatory response.

Stoecklin G, Anderson P.

Adv Immunol. 2006;89:1-37. Review.

PMID:
16682271
45.

Turnover in the Alps: an mRNA perspective. Workshops on mechanisms and regulation of mRNA turnover.

Newbury SF, Mühlemann O, Stoecklin G.

EMBO Rep. 2006 Feb;7(2):143-8. No abstract available.

46.

ARE-mRNA degradation requires the 5'-3' decay pathway.

Stoecklin G, Mayo T, Anderson P.

EMBO Rep. 2006 Jan;7(1):72-7.

47.

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling.

Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, Scheuner D, Kaufman RJ, Golan DE, Anderson P.

J Cell Biol. 2005 Jun 20;169(6):871-84.

48.

The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B.

Schmidlin M, Lu M, Leuenberger SA, Stoecklin G, Mallaun M, Gross B, Gherzi R, Hess D, Hemmings BA, Moroni C.

EMBO J. 2004 Dec 8;23(24):4760-9. Epub 2004 Nov 11.

49.

Stress granule assembly is mediated by prion-like aggregation of TIA-1.

Gilks N, Kedersha N, Ayodele M, Shen L, Stoecklin G, Dember LM, Anderson P.

Mol Biol Cell. 2004 Dec;15(12):5383-98. Epub 2004 Sep 15.

50.

Post-transcriptional regulation of proinflammatory proteins.

Anderson P, Phillips K, Stoecklin G, Kedersha N.

J Leukoc Biol. 2004 Jul;76(1):42-7. Epub 2004 Apr 1. Review.

PMID:
15075353

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