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Items: 1 to 50 of 127

1.

Publisher Correction: Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling.

Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X.

Nature. 2019 Aug;572(7770):E20. doi: 10.1038/s41586-019-1480-0.

PMID:
31371811
2.

Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling.

Wu J, Minikes AM, Gao M, Bian H, Li Y, Stockwell BR, Chen ZN, Jiang X.

Nature. 2019 Aug;572(7769):402-406. doi: 10.1038/s41586-019-1426-6. Epub 2019 Jul 24. Erratum in: Nature. 2019 Aug 2;:.

PMID:
31341276
3.

A Physiological Function for Ferroptosis in Tumor Suppression by the Immune System.

Stockwell BR, Jiang X.

Cell Metab. 2019 Jul 2;30(1):14-15. doi: 10.1016/j.cmet.2019.06.012.

PMID:
31269423
4.

K-RasG12D Has a Potential Allosteric Small Molecule Binding Site.

Feng H, Zhang Y, Bos PH, Chambers JM, Dupont MM, Stockwell BR.

Biochemistry. 2019 May 28;58(21):2542-2554. doi: 10.1021/acs.biochem.8b01300. Epub 2019 May 14.

PMID:
31042025
5.

Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model.

Zhang Y, Tan H, Daniels JD, Zandkarimi F, Liu H, Brown LM, Uchida K, O'Connor OA, Stockwell BR.

Cell Chem Biol. 2019 May 16;26(5):623-633.e9. doi: 10.1016/j.chembiol.2019.01.008. Epub 2019 Feb 21.

PMID:
30799221
6.

A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress.

Thams S, Lowry ER, Larraufie MH, Spiller KJ, Li H, Williams DJ, Hoang P, Jiang E, Williams LA, Sandoe J, Eggan K, Lieberam I, Kanning KC, Stockwell BR, Henderson CE, Wichterle H.

Mol Ther. 2019 Jan 2;27(1):87-101. doi: 10.1016/j.ymthe.2018.10.010. Epub 2018 Oct 19.

PMID:
30446391
7.

The development of the concept of ferroptosis.

Hirschhorn T, Stockwell BR.

Free Radic Biol Med. 2019 Mar;133:130-143. doi: 10.1016/j.freeradbiomed.2018.09.043. Epub 2018 Sep 28. Review.

PMID:
30268886
8.

Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator.

Wang C, Aleksandrov AA, Yang Z, Forouhar F, Proctor EA, Kota P, An J, Kaplan A, Khazanov N, Boël G, Stockwell BR, Senderowitz H, Dokholyan NV, Riordan JR, Brouillette CG, Hunt JF.

J Biol Chem. 2018 Nov 16;293(46):17685-17704. doi: 10.1074/jbc.RA117.000819. Epub 2018 Jun 14.

PMID:
29903914
9.

Regulation of lipid peroxidation and ferroptosis in diverse species.

Conrad M, Kagan VE, Bayir H, Pagnussat GC, Head B, Traber MG, Stockwell BR.

Genes Dev. 2018 May 1;32(9-10):602-619. doi: 10.1101/gad.314674.118. Review.

10.

Unsolved mysteries: How does lipid peroxidation cause ferroptosis?

Feng H, Stockwell BR.

PLoS Biol. 2018 May 24;16(5):e2006203. doi: 10.1371/journal.pbio.2006203. eCollection 2018 May.

11.

Increased erythrophagocytosis induces ferroptosis in red pulp macrophages in a mouse model of transfusion.

Youssef LA, Rebbaa A, Pampou S, Weisberg SP, Stockwell BR, Hod EA, Spitalnik SL.

Blood. 2018 Jun 7;131(23):2581-2593. doi: 10.1182/blood-2017-12-822619. Epub 2018 Apr 17.

12.

FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation.

Gaschler MM, Andia AA, Liu H, Csuka JM, Hurlocker B, Vaiana CA, Heindel DW, Zuckerman DS, Bos PH, Reznik E, Ye LF, Tyurina YY, Lin AJ, Shchepinov MS, Chan AY, Peguero-Pereira E, Fomich MA, Daniels JD, Bekish AV, Shmanai VV, Kagan VE, Mahal LK, Woerpel KA, Stockwell BR.

Nat Chem Biol. 2018 May;14(5):507-515. doi: 10.1038/s41589-018-0031-6. Epub 2018 Apr 2.

13.

Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy.

Liu H, Schreiber SL, Stockwell BR.

Biochemistry. 2018 Apr 10;57(14):2059-2060. doi: 10.1021/acs.biochem.8b00307. Epub 2018 Mar 27. Review. No abstract available.

14.

Modeling the effects of lipid peroxidation during ferroptosis on membrane properties.

Agmon E, Solon J, Bassereau P, Stockwell BR.

Sci Rep. 2018 Mar 26;8(1):5155. doi: 10.1038/s41598-018-23408-0.

15.

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

Shimada K, Reznik E, Stokes ME, Krishnamoorthy L, Bos PH, Song Y, Quartararo CE, Pagano NC, Carpizo DR, deCarvalho AC, Lo DC, Stockwell BR.

Cell Chem Biol. 2018 May 17;25(5):585-594.e7. doi: 10.1016/j.chembiol.2018.02.010. Epub 2018 Mar 22.

16.

Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis.

Gaschler MM, Hu F, Feng H, Linkermann A, Min W, Stockwell BR.

ACS Chem Biol. 2018 Apr 20;13(4):1013-1020. doi: 10.1021/acschembio.8b00199. Epub 2018 Mar 13.

17.

Small molecule modulator of protein disulfide isomerase attenuates mutant huntingtin toxicity and inhibits endoplasmic reticulum stress in a mouse model of Huntington's disease.

Zhou X, Li G, Kaplan A, Gaschler MM, Zhang X, Hou Z, Jiang M, Zott R, Cremers S, Stockwell BR, Duan W.

Hum Mol Genet. 2018 May 1;27(9):1545-1555. doi: 10.1093/hmg/ddy061.

18.

Toward a Microparticle-Based System for Pooled Assays of Small Molecules in Cellular Contexts.

Yozwiak CE, Hirschhorn T, Stockwell BR.

ACS Chem Biol. 2018 Mar 16;13(3):761-771. doi: 10.1021/acschembio.8b00043. Epub 2018 Feb 8.

19.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

20.

Design of Small Molecules That Compete with Nucleotide Binding to an Engineered Oncogenic KRAS Allele.

Zhang Y, Larraufie MH, Musavi L, Akkiraju H, Brown LM, Stockwell BR.

Biochemistry. 2018 Feb 27;57(8):1380-1389. doi: 10.1021/acs.biochem.7b01113. Epub 2018 Feb 6.

21.

Transforming Lipoxygenases: PE-Specific Enzymes in Disguise.

Ye LF, Stockwell BR.

Cell. 2017 Oct 19;171(3):501-502. doi: 10.1016/j.cell.2017.10.006.

22.

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.

Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.

Cell. 2017 Oct 5;171(2):273-285. doi: 10.1016/j.cell.2017.09.021. Review.

23.

Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs.

Figuera-Losada M, Thomas AG, Stathis M, Stockwell BR, Rojas C, Slusher BS.

Biochem Biophys Rep. 2017 Jan 17;9:266-272. doi: 10.1016/j.bbrep.2016.12.009. eCollection 2017 Mar.

24.

Group Problem Solving in Class Improves Undergraduate Learning.

Stockwell BR, Stockwell MS, Jiang E.

ACS Cent Sci. 2017 Jun 28;3(6):614-620. doi: 10.1021/acscentsci.7b00133. Epub 2017 May 30.

25.

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway.

Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, Chen S, Boskovic ZV, Javaid S, Huang C, Wu X, Tseng YY, Roider EM, Gao D, Cleary JM, Wolpin BM, Mesirov JP, Haber DA, Engelman JA, Boehm JS, Kotz JD, Hon CS, Chen Y, Hahn WC, Levesque MP, Doench JG, Berens ME, Shamji AF, Clemons PA, Stockwell BR, Schreiber SL.

Nature. 2017 Jul 27;547(7664):453-457. doi: 10.1038/nature23007. Epub 2017 Jul 5.

26.

Lipid homeostasis and regulated cell death.

Agmon E, Stockwell BR.

Curr Opin Chem Biol. 2017 Aug;39:83-89. doi: 10.1016/j.cbpa.2017.06.002. Epub 2017 Jun 20. Review.

27.

Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure.

Müller T, Dewitz C, Schmitz J, Schröder AS, Bräsen JH, Stockwell BR, Murphy JM, Kunzendorf U, Krautwald S.

Cell Mol Life Sci. 2017 Oct;74(19):3631-3645. doi: 10.1007/s00018-017-2547-4. Epub 2017 May 27.

28.

Inhibition of neuronal ferroptosis protects hemorrhagic brain.

Li Q, Han X, Lan X, Gao Y, Wan J, Durham F, Cheng T, Yang J, Wang Z, Jiang C, Ying M, Koehler RC, Stockwell BR, Wang J.

JCI Insight. 2017 Apr 6;2(7):e90777. doi: 10.1172/jci.insight.90777.

29.

Multivalent Small-Molecule Pan-RAS Inhibitors.

Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, Yang WS, Tong L, Olive KP, Ferrando A, Stockwell BR.

Cell. 2017 Feb 23;168(5):878-889.e29. doi: 10.1016/j.cell.2017.02.006.

30.

Lipid peroxidation in cell death.

Gaschler MM, Stockwell BR.

Biochem Biophys Res Commun. 2017 Jan 15;482(3):419-425. doi: 10.1016/j.bbrc.2016.10.086. Epub 2017 Feb 3. Review.

31.

Heat stress induces ferroptosis-like cell death in plants.

Distéfano AM, Martin MV, Córdoba JP, Bellido AM, D'Ippólito S, Colman SL, Soto D, Roldán JA, Bartoli CG, Zabaleta EJ, Fiol DF, Stockwell BR, Dixon SJ, Pagnussat GC.

J Cell Biol. 2017 Feb;216(2):463-476. doi: 10.1083/jcb.201605110. Epub 2017 Jan 18.

32.

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.

Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H.

Nat Chem Biol. 2017 Jan;13(1):81-90. doi: 10.1038/nchembio.2238. Epub 2016 Nov 14.

33.

Discovery of Anticancer Agents of Diverse Natural Origin.

Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, Zhang X, Shen YY.

Anticancer Res. 2016 Nov;36(11):5623-5637. Review.

34.

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis.

Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P.

ACS Cent Sci. 2016 Sep 28;2(9):653-659. Epub 2016 Sep 7.

35.

Clickable Poly(ionic liquids): A Materials Platform for Transfection.

Freyer JL, Brucks SD, Gobieski GS, Russell ST, Yozwiak CE, Sun M, Chen Z, Jiang Y, Bandar JS, Stockwell BR, Lambert TH, Campos LM.

Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12382-6. doi: 10.1002/anie.201605214. Epub 2016 Aug 31.

36.

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR.

Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E4966-75. doi: 10.1073/pnas.1603244113. Epub 2016 Aug 9.

37.

tRNA synthase suppression activates de novo cysteine synthesis to compensate for cystine and glutathione deprivation during ferroptosis.

Shimada K, Stockwell BR.

Mol Cell Oncol. 2015 Oct 6;3(2):e1091059. doi: 10.1080/23723556.2015.1091059. eCollection 2016 Mar.

38.

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

Shimada K, Skouta R, Kaplan A, Yang WS, Hayano M, Dixon SJ, Brown LM, Valenzuela CA, Wolpaw AJ, Stockwell BR.

Nat Chem Biol. 2016 Jul;12(7):497-503. doi: 10.1038/nchembio.2079. Epub 2016 May 9.

39.

Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity.

Shimada K, Hayano M, Pagano NC, Stockwell BR.

Cell Chem Biol. 2016 Feb 18;23(2):225-235. doi: 10.1016/j.chembiol.2015.11.016. Epub 2016 Feb 4.

40.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de 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41.

Regulated necrosis: disease relevance and therapeutic opportunities.

Conrad M, Angeli JP, Vandenabeele P, Stockwell BR.

Nat Rev Drug Discov. 2016 May;15(5):348-66. doi: 10.1038/nrd.2015.6. Epub 2016 Jan 18. Review.

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Ferroptosis: Death by Lipid Peroxidation.

Yang WS, Stockwell BR.

Trends Cell Biol. 2016 Mar;26(3):165-176. doi: 10.1016/j.tcb.2015.10.014. Epub 2015 Dec 2. Review.

43.

Structural Elucidation of a Small Molecule Inhibitor of Protein Disulfide Isomerase.

Kaplan A, Stockwell BR.

ACS Med Chem Lett. 2015 Jul 29;6(9):966-971. eCollection 2015 Sep 10.

44.

Blended Learning Improves Science Education.

Stockwell BR, Stockwell MS, Cennamo M, Jiang E.

Cell. 2015 Aug 27;162(5):933-6. doi: 10.1016/j.cell.2015.08.009.

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High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma.

Quartararo CE, Reznik E, deCarvalho AC, Mikkelsen T, Stockwell BR.

ACS Med Chem Lett. 2015 Jun 22;6(8):948-52. doi: 10.1021/acsmedchemlett.5b00128. eCollection 2015 Aug 13.

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Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility.

Larraufie MH, Yang WS, Jiang E, Thomas AG, Slusher BS, Stockwell BR.

Bioorg Med Chem Lett. 2015 Nov 1;25(21):4787-4792. doi: 10.1016/j.bmcl.2015.07.018. Epub 2015 Jul 14.

47.

Elucidating Compound Mechanism of Action by Network Perturbation Analysis.

Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A.

Cell. 2015 Jul 16;162(2):441-451. doi: 10.1016/j.cell.2015.05.056.

48.

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation.

Hayano M, Yang WS, Corn CK, Pagano NC, Stockwell BR.

Cell Death Differ. 2016 Feb;23(2):270-8. doi: 10.1038/cdd.2015.93. Epub 2015 Jul 17.

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death.

Dixon SJ, Winter GE, Musavi LS, Lee ED, Snijder B, Rebsamen M, Superti-Furga G, Stockwell BR.

ACS Chem Biol. 2015 Jul 17;10(7):1604-9. doi: 10.1021/acschembio.5b00245. Epub 2015 May 15.

50.

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective.

Kaplan A, Gaschler MM, Dunn DE, Colligan R, Brown LM, Palmer AG 3rd, Lo DC, Stockwell BR.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2245-52. doi: 10.1073/pnas.1500439112. Epub 2015 Apr 6.

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