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Items: 1 to 50 of 374

1.

Efficacy and safety of inhaled alpha-1-antitrypsin in patients with severe alpha-1-antitrypsin deficiency and frequent exacerbations of Chronic Obstructive Pulmonary Disease.

Stolk J, Tov N, Chapman KR, Fernandez P, MacNee W, Hopkinson NS, Piitulainen E, Seersholm N, Vogelmeier CF, Bals R, McElvaney G, Stockley RA.

Eur Respir J. 2019 Aug 29. pii: 1900673. doi: 10.1183/13993003.00673-2019. [Epub ahead of print]

PMID:
31467115
2.

A specific proteinase 3 activity footprint in α1-antitrypsin deficiency.

Newby PR, Crossley D, Crisford H, Stockley JA, Mumford RA, Carter RI, Bolton CE, Hopkinson NS, Mahadeva R, Steiner MC, Wilkinson TMA, Sapey E, Stockley RA.

ERJ Open Res. 2019 Aug 5;5(3). pii: 00095-2019. doi: 10.1183/23120541.00095-2019. eCollection 2019 Jul.

3.

Alpha-1 Antitrypsin Deficiency: A Predisposing Factor for the Development of Pulmonary Langerhans Cell Histiocytosis.

Ellis PR, Campbell EJ, Turner AM, Stockley RA.

Chronic Obstr Pulm Dis. 2019 Jul 24;6(3):206-209. doi: 10.15326/jcopdf.6.3.2019.0129. No abstract available.

4.

Corporate Memory and Rediscovering the Wheel.

Stockley RA.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):2-4. doi: 10.1164/rccm.201901-0066ED. No abstract available.

5.

Getting stuck or choosing to stay? Neutrophil transit times in the lung in acute inflammation and COPD.

Sapey E, Stockley RA.

Thorax. 2019 Jul;74(7):631-632. doi: 10.1136/thoraxjnl-2018-213000. Epub 2019 May 16. No abstract available.

6.

The Biological Effects of Double-Dose Alpha-1 Antitrypsin Augmentation Therapy. A Pilot Clinical Trial.

Campos MA, Geraghty P, Holt G, Mendes E, Newby PR, Ma S, Luna-Diaz LV, Turino GM, Stockley RA.

Am J Respir Crit Care Med. 2019 Aug 1;200(3):318-326. doi: 10.1164/rccm.201901-0010OC.

7.

Reply to Pouwels et al.: Confounding Factors Affecting sRAGE as a Biomarker for Chronic Obstructive Pulmonary Disease.

Stockley RA, Halpin D, Celli BR, Singh D.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):114-115. doi: 10.1164/rccm.201903-0573LE. No abstract available.

8.

The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency.

Miravitlles M, Chorostowska-Wynimko J, Ferrarotti I, McElvaney NG, O'Hara K, Stolk J, Stockley RA, Turner A, Wilkens M, Greulich T; EARCO Clinical Research Collaboration; Members of the EARCO Clinical Research Collaboration.

Eur Respir J. 2019 Feb 14;53(2). pii: 1900138. doi: 10.1183/13993003.00138-2019. Print 2019 Feb. No abstract available.

PMID:
30765486
9.

Chronic Obstructive Pulmonary Disease Biomarkers and Their Interpretation.

Stockley RA, Halpin DMG, Celli BR, Singh D.

Am J Respir Crit Care Med. 2019 May 15;199(10):1195-1204. doi: 10.1164/rccm.201810-1860SO.

PMID:
30592902
10.

Proteinase 3; a potential target in chronic obstructive pulmonary disease and other chronic inflammatory diseases.

Crisford H, Sapey E, Stockley RA.

Respir Res. 2018 Sep 20;19(1):180. doi: 10.1186/s12931-018-0883-z. Review.

11.

Health status decline in α-1 antitrypsin deficiency: a feasible outcome for disease modifying therapies?

Stockley RA, Edgar RG, Starkey S, Turner AM.

Respir Res. 2018 Jul 20;19(1):137. doi: 10.1186/s12931-018-0844-6.

12.

ICS Use May Modify FEV1 Decline in α1-Antitrypsin Deficiency Patients with Relatively High Blood Eosinophils.

Low EV, Hughes SM, Zaffarullah S, Kantas D, Stockley RA, Turner AM.

Respiration. 2018;95(2):114-121. doi: 10.1159/000481867. Epub 2017 Dec 18.

13.

European Respiratory Society statement: diagnosis and treatment of pulmonary disease in α1-antitrypsin deficiency.

Miravitlles M, Dirksen A, Ferrarotti I, Koblizek V, Lange P, Mahadeva R, McElvaney NG, Parr D, Piitulainen E, Roche N, Stolk J, Thabut G, Turner A, Vogelmeier C, Stockley RA.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700610. doi: 10.1183/13993003.00610-2017. Print 2017 Nov. Review.

14.

COPD10: Birmingham,United Kingdom, July 2016.

Stockley RA.

Chronic Obstr Pulm Dis. 2017 Jul 15;4(3):225-246. doi: 10.15326/jcopdf.4.3.2017.0137. No abstract available.

15.

Small airways disease: time for a revisit?

Stockley JA, Cooper BG, Stockley RA, Sapey E.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 7;12:2343-2353. doi: 10.2147/COPD.S138540. eCollection 2017. Review.

16.

Is periodontitis a comorbidity of COPD or can associations be explained by shared risk factors/behaviors?

Hobbins S, Chapple IL, Sapey E, Stockley RA.

Int J Chron Obstruct Pulmon Dis. 2017 May 4;12:1339-1349. doi: 10.2147/COPD.S127802. eCollection 2017. Review.

17.

The Use of Plasmapheresis in Patients with Bronchiectasis with Pseudomonas aeruginosa Infection and Inhibitory Antibodies.

Wells TJ, Davison J, Sheehan E, Kanagasundaram S, Spickett G, MacLennan CA, Stockley RA, Cunningham AF, Henderson IR, De Soyza A.

Am J Respir Crit Care Med. 2017 Apr 1;195(7):955-958. doi: 10.1164/rccm.201603-0599LE. No abstract available.

PMID:
28362198
18.

Post Hoc: Two (or More) for the Price of One.

Stockley RA.

Am J Respir Crit Care Med. 2017 Apr 1;195(7):844-846. doi: 10.1164/rccm.201610-2132ED. No abstract available.

PMID:
28362196
19.

Maximal mid-expiratory flow detects early lung disease in α1-antitrypsin deficiency.

Stockley JA, Ismail AM, Hughes SM, Edgar R, Stockley RA, Sapey E.

Eur Respir J. 2017 Mar 29;49(3). pii: 1602055. doi: 10.1183/13993003.02055-2016. Print 2017 Mar.

20.

Patterns and characterization of COPD exacerbations using real-time data collection.

Ejiofor SI, Stolk J, Fernandez P, Stockley RA.

Int J Chron Obstruct Pulmon Dis. 2017 Jan 25;12:427-434. doi: 10.2147/COPD.S126158. eCollection 2017.

22.

Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis.

Dau T, Edeleva EV, Seidel SA, Stockley RA, Braun D, Jenne DE.

Sci Rep. 2016 Oct 14;6:35413. doi: 10.1038/srep35413.

23.

Alpha-1 Antitrypsin Deficiency: Phenotypes and Quality of Life.

Stockley RA.

Ann Am Thorac Soc. 2016 Aug;13 Suppl 4:S332-5. doi: 10.1513/AnnalsATS.201507-436KV. Review.

PMID:
27564669
24.

Individualized lung function trends in alpha-1-antitrypsin deficiency: a need for patience in order to provide patient centered management?

Stockley RA, Edgar RG, Pillai A, Turner AM.

Int J Chron Obstruct Pulmon Dis. 2016 Aug 1;11:1745-56. doi: 10.2147/COPD.S111508. eCollection 2016.

25.

Cohort Profile: The Birmingham Chronic Obstructive Pulmonary Disease (COPD) Cohort Study.

Adab P, Fitzmaurice DA, Dickens AP, Ayres JG, Buni H, Cooper BG, Daley AJ, Enocson A, Greenfield S, Jolly K, Jowett S, Kalirai K, Marsh JL, Miller MR, Riley RD, Siebert WS, Stockley RA, Turner AM, Cheng KK, Jordan RE.

Int J Epidemiol. 2017 Feb 1;46(1):23. doi: 10.1093/ije/dyv350. No abstract available.

PMID:
27378796
26.

COPD service delivery in the UK.

Stockley RA.

Lancet Respir Med. 2016 Jun;4(6):426-8. doi: 10.1016/S2213-2600(16)30082-0. Epub 2016 May 13. Review. No abstract available.

PMID:
27185521
27.

Pulmonary Physiology of Chronic Obstructive Pulmonary Disease, Cystic Fibrosis, and Alpha-1 Antitrypsin Deficiency.

Stockley JA, Stockley RA.

Ann Am Thorac Soc. 2016 Apr;13 Suppl 2:S118-22. doi: 10.1513/AnnalsATS.201504-224KV.

PMID:
27115945
28.

Free light chains: potential biomarker and predictor of mortality in alpha-1-antitrypsin deficiency and usual COPD.

Hampson JA, Stockley RA, Turner AM.

Respir Res. 2016 Mar 31;17:34. doi: 10.1186/s12931-016-0348-1.

29.

Lung density associates with survival in alpha 1 antitrypsin deficient patients.

Green CE, Parr DG, Edgar RG, Stockley RA, Turner AM.

Respir Med. 2016 Mar;112:81-7. doi: 10.1016/j.rmed.2016.01.007. Epub 2016 Jan 22.

31.

Lung Transplantation in Alpha-1-Antitrypsin Deficiency.

Stone HM, Edgar RG, Thompson RD, Stockley RA.

COPD. 2016;13(2):146-52. doi: 10.3109/15412555.2015.1048850. Epub 2015 Oct 21.

PMID:
26488418
32.

The multiple facets of alpha-1-antitrypsin.

Stockley RA.

Ann Transl Med. 2015 Jun;3(10):130. doi: 10.3978/j.issn.2305-5839.2015.04.25.

33.

PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD.

Green CE, Vayalapra S, Hampson JA, Mukherjee D, Stockley RA, Turner AM.

Thorax. 2015 Oct;70(10):939-45. doi: 10.1136/thoraxjnl-2015-206906. Epub 2015 Jul 3.

PMID:
26141072
34.

Relationship between Change in Lung Density and Long-Term Progression of Lung Function.

Stolk J, Stockley RA, Piitulainen E, Stoel BC.

Am J Respir Crit Care Med. 2015 Jul 1;192(1):114-6. doi: 10.1164/rccm.201502-0370LE. No abstract available.

PMID:
26131993
35.

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL; ATS/ERS Task Force for COPD Research.

Eur Respir Rev. 2015 Jun;24(136):159-72. doi: 10.1183/16000617.00000315. Review.

36.

α1-antitrypsin: a polyfunctional protein?

Stockley RA.

Lancet Respir Med. 2015 May;3(5):341-3. doi: 10.1016/S2213-2600(15)00094-6. Review. No abstract available.

PMID:
25969357
37.

Antitrypsin Deficiency Assessment and Programme for Treatment (ADAPT): The United Kingdom Registry.

Stockley RA.

COPD. 2015 May;12 Suppl 1:63-8. doi: 10.3109/15412555.2015.1021911.

PMID:
25938295
38.

An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease.

Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL; ATS/ERS Task Force for COPD Research.

Am J Respir Crit Care Med. 2015 Apr 1;191(7):e4-e27. doi: 10.1164/rccm.201501-0044ST.

PMID:
25830527
39.

An official American Thoracic Society/European Respiratory Society statement: research questions in COPD.

Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, Calverley PM, Casanova C, Clini EM, Cooper CB, Coxson HO, Dusser DJ, Fabbri LM, Fahy B, Ferguson GT, Fisher A, Fletcher MJ, Hayot M, Hurst JR, Jones PW, Mahler DA, Maltais F, Mannino DM, Martinez FJ, Miravitlles M, Meek PM, Papi A, Rabe KF, Roche N, Sciurba FC, Sethi S, Siafakas N, Sin DD, Soriano JB, Stoller JK, Tashkin DP, Troosters T, Verleden GM, Verschakelen J, Vestbo J, Walsh JW, Washko GR, Wise RA, Wouters EF, ZuWallack RL; ATS/ERS Task Force for COPD Research.

Eur Respir J. 2015 Apr;45(4):879-905. doi: 10.1183/09031936.00009015. Review.

40.

COPD9: Birmingham, United Kingdom, June 2014.

Stockley RA.

Chronic Obstr Pulm Dis. 2015 Apr 1;2(2):152-176. doi: 10.15326/jcopdf.2.2.2014.0158. No abstract available.

41.

Immune modulation by α1-antitrypsin. A nice concept, but does it influence outcome?

Stockley RA.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):363-4. doi: 10.1164/rccm.201412-2129ED. No abstract available.

PMID:
25679099
42.

The Relationship of the Fibrinogen Cleavage Biomarker Aα-Val360 With Disease Severity and Activity in α1-Antitrypsin Deficiency.

Carter RI, Ungurs MJ, Pillai A, Mumford RA, Stockley RA.

Chest. 2015 Aug;148(2):382-388. doi: 10.1378/chest.14-0520.

PMID:
25569856
43.

α-1-antitrypsin variants and the proteinase/antiproteinase imbalance in chronic obstructive pulmonary disease.

Sinden NJ, Baker MJ, Smith DJ, Kreft JU, Dafforn TR, Stockley RA.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L179-90.

44.

TargetCOPD: a pragmatic randomised controlled trial of targeted case finding for COPD versus routine practice in primary care: protocol.

Jordan RE, Adab P, Jowett S, Marsh JL, Riley RD, Enocson A, Miller MR, Cooper BG, Turner AM, Ayres JG, Cheng KK, Jolly K, Stockley RA, Greenfield S, Siebert S, Daley A, Fitzmaurice DA.

BMC Pulm Med. 2014 Oct 4;14:157. doi: 10.1186/1471-2466-14-157.

45.

Prevention of Exacerbations in Chronic Obstructive Pulmonary Disease: Knowns and Unknowns.

Agustí A, Calverley PM, Decramer M, Stockley RA, Wedzicha JA.

Chronic Obstr Pulm Dis. 2014 Sep 25;1(2):166-184. doi: 10.15326/jcopdf.1.2.2014.0134. Review.

46.

Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing.

Wells TJ, Whitters D, Sevastsyanovich YR, Heath JN, Pravin J, Goodall M, Browning DF, O'Shea MK, Cranston A, De Soyza A, Cunningham AF, MacLennan CA, Henderson IR, Stockley RA.

J Exp Med. 2014 Aug 25;211(9):1893-904. doi: 10.1084/jem.20132444. Epub 2014 Aug 11.

47.

The significance of the F variant of alpha-1-antitrypsin and unique case report of a PiFF homozygote.

Sinden NJ, Koura F, Stockley RA.

BMC Pulm Med. 2014 Aug 7;14:132. doi: 10.1186/1471-2466-14-132.

48.

Relationship of the 2011 Global Initiative for Chronic Obstructive Lung Disease strategy to clinically relevant outcomes in individuals with α1-antitrypsin deficiency.

Pillai AP, Turner AM, Stockley RA.

Ann Am Thorac Soc. 2014 Jul;11(6):859-64. doi: 10.1513/AnnalsATS.201311-380OC.

PMID:
24950156
49.

Red, amber and green: the role of the lung in de-priming active systemic neutrophils.

Sapey E, Stockley RA.

Thorax. 2014 Jul;69(7):606-8. doi: 10.1136/thoraxjnl-2014-205438. No abstract available.

PMID:
24917612
50.

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