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Items: 24


In vivo chloride concentrations surge to proteotoxic levels during acid stress.

Stull F, Hipp H, Stockbridge RB, Bardwell JCA.

Nat Chem Biol. 2018 Nov;14(11):1051-1058. doi: 10.1038/s41589-018-0143-z. Epub 2018 Oct 15.


A clearer image of the structure and regulation of bestrophin.

Stockbridge RB.

J Gen Physiol. 2018 Nov 5;150(11):1469-1471. doi: 10.1085/jgp.201812220. Epub 2018 Oct 15. No abstract available.


A CLC-type F-/H+ antiporter in ion-swapped conformations.

Last NB, Stockbridge RB, Wilson AE, Shane T, Kolmakova-Partensky L, Koide A, Koide S, Miller C.

Nat Struct Mol Biol. 2018 Jul;25(7):601-606. doi: 10.1038/s41594-018-0082-0. Epub 2018 Jun 25.


Cork-in-Bottle Occlusion of Fluoride Ion Channels by Crystallization Chaperones.

McIlwain BC, Newstead S, Stockbridge RB.

Structure. 2018 Apr 3;26(4):635-639.e1. doi: 10.1016/j.str.2018.02.004. Epub 2018 Mar 8.


Guanidinium export is the primal function of SMR family transporters.

Kermani AA, Macdonald CB, Gundepudi R, Stockbridge RB.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3060-3065. doi: 10.1073/pnas.1719187115. Epub 2018 Mar 5.


A topologically diverse family of fluoride channels.

Macdonald CB, Stockbridge RB.

Curr Opin Struct Biol. 2017 Aug;45:142-149. doi: 10.1016/ Epub 2017 May 14. Review.


Mechanism of single- and double-sided inhibition of dual topology fluoride channels by synthetic monobodies.

Turman DL, Stockbridge RB.

J Gen Physiol. 2017 Apr 3;149(4):511-522. doi: 10.1085/jgp.201611747. Epub 2017 Mar 3.


Metabolism of Free Guanidine in Bacteria Is Regulated by a Widespread Riboswitch Class.

Nelson JW, Atilho RM, Sherlock ME, Stockbridge RB, Breaker RR.

Mol Cell. 2017 Jan 19;65(2):220-230. doi: 10.1016/j.molcel.2016.11.019. Epub 2016 Dec 15.


Crystal structures of a double-barrelled fluoride ion channel.

Stockbridge RB, Kolmakova-Partensky L, Shane T, Koide A, Koide S, Miller C, Newstead S.

Nature. 2015 Sep 24;525(7570):548-51. doi: 10.1038/nature14981. Epub 2015 Sep 7.


Two-sided block of a dual-topology F- channel.

Turman DL, Nathanson JT, Stockbridge RB, Street TO, Miller C.

Proc Natl Acad Sci U S A. 2015 May 5;112(18):5697-701. doi: 10.1073/pnas.1505301112. Epub 2015 Apr 20.


Lipid reconstitution and recording of recombinant ion channels.

Stockbridge RB, Tsai MF.

Methods Enzymol. 2015;556:385-404. doi: 10.1016/bs.mie.2014.12.028. Epub 2015 Mar 21.


Proof of dual-topology architecture of Fluc F- channels with monobody blockers.

Stockbridge RB, Koide A, Miller C, Koide S.

Nat Commun. 2014 Oct 7;5:5120. doi: 10.1038/ncomms6120.


Bacterial fluoride resistance, Fluc channels, and the weak acid accumulation effect.

Ji C, Stockbridge RB, Miller C.

J Gen Physiol. 2014 Sep;144(3):257-61. doi: 10.1085/jgp.201411243.


F-/Cl- selectivity in CLCF-type F-/H+ antiporters.

Brammer AE, Stockbridge RB, Miller C.

J Gen Physiol. 2014 Aug;144(2):129-36. doi: 10.1085/jgp.201411225.


Fluoride-dependent interruption of the transport cycle of a CLC Cl-/H+ antiporter.

Lim HH, Stockbridge RB, Miller C.

Nat Chem Biol. 2013 Nov;9(11):721-5. doi: 10.1038/nchembio.1336. Epub 2013 Sep 15.


A family of fluoride-specific ion channels with dual-topology architecture.

Stockbridge RB, Robertson JL, Kolmakova-Partensky L, Miller C.

Elife. 2013 Aug 27;2:e01084. doi: 10.7554/eLife.01084. Erratum in: Elife. 2013;2:e01700.


Fluoride resistance and transport by riboswitch-controlled CLC antiporters.

Stockbridge RB, Lim HH, Otten R, Williams C, Shane T, Weinberg Z, Miller C.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15289-94. Epub 2012 Sep 4.


Widespread genetic switches and toxicity resistance proteins for fluoride.

Baker JL, Sudarsan N, Weinberg Z, Roth A, Stockbridge RB, Breaker RR.

Science. 2012 Jan 13;335(6065):233-235. doi: 10.1126/science.1215063. Epub 2011 Dec 22.


Enhancement of the rate of pyrophosphate hydrolysis by nonenzymatic catalysts and by inorganic pyrophosphatase.

Stockbridge RB, Wolfenden R.

J Biol Chem. 2011 May 27;286(21):18538-46. doi: 10.1074/jbc.M110.214510. Epub 2011 Apr 1.


Impact of temperature on the time required for the establishment of primordial biochemistry, and for the evolution of enzymes.

Stockbridge RB, Lewis CA Jr, Yuan Y, Wolfenden R.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22102-5. doi: 10.1073/pnas.1013647107. Epub 2010 Dec 1.


The rate of spontaneous cleavage of the glycosidic bond of adenosine.

Stockbridge RB, Schroeder GK, Wolfenden R.

Bioorg Chem. 2010 Oct;38(5):224-8. doi: 10.1016/j.bioorg.2010.05.003. Epub 2010 Jun 4.


The hydrolysis of phosphate diesters in cyclohexane and acetone.

Stockbridge RB, Wolfenden R.

Chem Commun (Camb). 2010 Jun 28;46(24):4306-8. doi: 10.1039/c0cc00229a. Epub 2010 May 6.


Phosphate monoester hydrolysis in cyclohexane.

Stockbridge RB, Wolfenden R.

J Am Chem Soc. 2009 Dec 30;131(51):18248-9. doi: 10.1021/ja907967y.


The intrinsic reactivity of ATP and the catalytic proficiencies of kinases acting on glucose, N-acetylgalactosamine, and homoserine: a thermodynamic analysis.

Stockbridge RB, Wolfenden R.

J Biol Chem. 2009 Aug 21;284(34):22747-57. doi: 10.1074/jbc.M109.017806. Epub 2009 Jun 15.

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