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Items: 6


Impaired DNA Repair as a Mechanism for Oocyte Aging: Is It Epigenetically Determined?

Titus S, Stobezki R, Oktay K.

Semin Reprod Med. 2015 Nov;33(6):384-8. doi: 10.1055/s-0035-1567824. Epub 2015 Nov 12. Review.


BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging.

Oktay K, Turan V, Titus S, Stobezki R, Liu L.

Biol Reprod. 2015 Sep;93(3):67. doi: 10.1095/biolreprod.115.132290. Epub 2015 Jul 29. Review.


Age-related decline in DNA repair function explains diminished ovarian reserve, earlier menopause, and possible oocyte vulnerability to chemotherapy in women with BRCA mutations.

Oktay K, Moy F, Titus S, Stobezki R, Turan V, Dickler M, Goswami S.

J Clin Oncol. 2014 Apr 1;32(10):1093-4. doi: 10.1200/JCO.2013.53.5369. Epub 2014 Feb 18. No abstract available.


Impairment of BRCA1-related DNA double-strand break repair leads to ovarian aging in mice and humans.

Titus S, Li F, Stobezki R, Akula K, Unsal E, Jeong K, Dickler M, Robson M, Moy F, Goswami S, Oktay K.

Sci Transl Med. 2013 Feb 13;5(172):172ra21. doi: 10.1126/scitranslmed.3004925.


Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer.

Roussos ET, Balsamo M, Alford SK, Wyckoff JB, Gligorijevic B, Wang Y, Pozzuto M, Stobezki R, Goswami S, Segall JE, Lauffenburger DA, Bresnick AR, Gertler FB, Condeelis JS.

J Cell Sci. 2011 Jul 1;124(Pt 13):2120-31. doi: 10.1242/jcs.086231.


Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM.

Roussos ET, Goswami S, Balsamo M, Wang Y, Stobezki R, Adler E, Robinson BD, Jones JG, Gertler FB, Condeelis JS, Oktay MH.

Clin Exp Metastasis. 2011 Aug;28(6):515-27. doi: 10.1007/s10585-011-9388-6. Epub 2011 Apr 12.

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