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Items: 19


Evaluation of the role of respiratory syncytial virus surface glycoproteins F and G on viral stability and replication: implications for future vaccine design.

DeFord DM, Nosek JM, Castiglia KR, Hasik EF, Franke ME, Nick BC, Abdelnour AM, Haas CE, Junod NA, Latsko KN, Moore ML, Berthrong ST, Rostad CA, Stobart CC.

J Gen Virol. 2019 Jul;100(7):1112-1122. doi: 10.1099/jgv.0.001287. Epub 2019 Jun 11.


A Contemporary View of Respiratory Syncytial Virus (RSV) Biology and Strain-Specific Differences.

Pandya MC, Callahan SM, Savchenko KG, Stobart CC.

Pathogens. 2019 May 21;8(2). pii: E67. doi: 10.3390/pathogens8020067. Review.


The Morphology and Assembly of Respiratory Syncytial Virus Revealed by Cryo-Electron Tomography.

Ke Z, Dillard RS, Chirkova T, Leon F, Stobart CC, Hampton CM, Strauss JD, Rajan D, Rostad CA, Taylor JV, Yi H, Shah R, Jin M, Hartert TV, Peebles RS Jr, Graham BS, Moore ML, Anderson LJ, Wright ER.

Viruses. 2018 Aug 20;10(8). pii: E446. doi: 10.3390/v10080446.


Polyvalent vaccines: High-maintenance heroes.

Schlingmann B, Castiglia KR, Stobart CC, Moore ML.

PLoS Pathog. 2018 Apr 5;14(4):e1006904. doi: 10.1371/journal.ppat.1006904. eCollection 2018 Apr. Review. No abstract available.


Enhancing the Thermostability and Immunogenicity of a Respiratory Syncytial Virus (RSV) Live-Attenuated Vaccine by Incorporating Unique RSV Line19F Protein Residues.

Rostad CA, Stobart CC, Todd SO, Molina SA, Lee S, Blanco JCG, Moore ML.

J Virol. 2018 Feb 26;92(6). pii: e01568-17. doi: 10.1128/JVI.01568-17. Print 2018 Mar 15.


Rhinovirus Biology, Antigenic Diversity, and Advancements in the Design of a Human Rhinovirus Vaccine.

Stobart CC, Nosek JM, Moore ML.

Front Microbiol. 2017 Dec 5;8:2412. doi: 10.3389/fmicb.2017.02412. eCollection 2017.


BAC-Based Recovery of Recombinant Respiratory Syncytial Virus (RSV).

Stobart CC, Hotard AL, Meng J, Moore ML.

Methods Mol Biol. 2017;1602:111-124. doi: 10.1007/978-1-4939-6964-7_8.


A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation.

Stobart CC, Rostad CA, Ke Z, Dillard RS, Hampton CM, Strauss JD, Yi H, Hotard AL, Meng J, Pickles RJ, Sakamoto K, Lee S, Currier MG, Moin SM, Graham BS, Boukhvalova MS, Gilbert BE, Blanco JC, Piedra PA, Wright ER, Moore ML.

Nat Commun. 2016 Dec 21;7:13916. doi: 10.1038/ncomms13916.


Reverse Genetics of Respiratory Syncytial Virus.

Stobart CC, Hotard AL, Meng J, Moore ML.

Methods Mol Biol. 2016;1442:141-53. doi: 10.1007/978-1-4939-3687-8_10.


A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats.

Rostad CA, Stobart CC, Gilbert BE, Pickles RJ, Hotard AL, Meng J, Blanco JCG, Moin SM, Graham BS, Piedra PA, Moore ML.

J Virol. 2016 Jul 27;90(16):7508-7518. doi: 10.1128/JVI.00012-16. Print 2016 Aug 15.


EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.

Currier MG, Lee S, Stobart CC, Hotard AL, Villenave R, Meng J, Pretto CD, Shields MD, Nguyen MT, Todd SO, Chi MH, Hammonds J, Krumm SA, Spearman P, Plemper RK, Sakamoto K, Peebles RS Jr, Power UF, Moore ML.

PLoS Pathog. 2016 May 6;12(5):e1005622. doi: 10.1371/journal.ppat.1005622. eCollection 2016 May.


Respiratory Syncytial Virus Attachment Glycoprotein Contribution to Infection Depends on the Specific Fusion Protein.

Meng J, Hotard AL, Currier MG, Lee S, Stobart CC, Moore ML.

J Virol. 2015 Oct 14;90(1):245-53. doi: 10.1128/JVI.02140-15. Print 2016 Jan 1.


Development of next-generation respiratory virus vaccines through targeted modifications to viral immunomodulatory genes.

Stobart CC, Moore ML.

Expert Rev Vaccines. 2015;14(12):1563-72. doi: 10.1586/14760584.2015.1095096. Epub 2015 Oct 5. Review.


CX3CR1 is an important surface molecule for respiratory syncytial virus infection in human airway epithelial cells.

Chirkova T, Lin S, Oomens AG, Gaston KA, Boyoglu-Barnum S, Meng J, Stobart CC, Cotton CU, Hartert TV, Moore ML, Ziady AG, Anderson LJ.

J Gen Virol. 2015 Sep;96(9):2543-56. doi: 10.1099/vir.0.000218. Epub 2015 Jun 25.


RNA virus reverse genetics and vaccine design.

Stobart CC, Moore ML.

Viruses. 2014 Jun 25;6(7):2531-50. doi: 10.3390/v6072531. Review.


An overview of respiratory syncytial virus.

Meng J, Stobart CC, Hotard AL, Moore ML.

PLoS Pathog. 2014 Apr 24;10(4):e1004016. doi: 10.1371/journal.ppat.1004016. eCollection 2014 Apr. Review. No abstract available.


Chimeric exchange of coronavirus nsp5 proteases (3CLpro) identifies common and divergent regulatory determinants of protease activity.

Stobart CC, Sexton NR, Munjal H, Lu X, Molland KL, Tomar S, Mesecar AD, Denison MR.

J Virol. 2013 Dec;87(23):12611-8. doi: 10.1128/JVI.02050-13. Epub 2013 Sep 11.


Murine hepatitis virus nonstructural protein 4 regulates virus-induced membrane modifications and replication complex function.

Gadlage MJ, Sparks JS, Beachboard DC, Cox RG, Doyle JD, Stobart CC, Denison MR.

J Virol. 2010 Jan;84(1):280-90. doi: 10.1128/JVI.01772-09.

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