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Items: 7


Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease.

Stirnweiss A, Oommen J, Kotecha RS, Kees UR, Beesley AH.

Oncotarget. 2017 Dec 2;8(68):112313-112329. doi: 10.18632/oncotarget.22862. eCollection 2017 Dec 22.


A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma.

Stirnweiss A, McCarthy K, Oommen J, Crook ML, Hardy K, Kees UR, Wilton SD, Anazodo A, Beesley AH.

Oncogenesis. 2015 Nov 9;4:e174. doi: 10.1038/oncsis.2015.33.


Comparative drug screening in NUT midline carcinoma.

Beesley AH, Stirnweiss A, Ferrari E, Endersby R, Howlett M, Failes TW, Arndt GM, Charles AK, Cole CH, Kees UR.

Br J Cancer. 2014 Mar 4;110(5):1189-98. doi: 10.1038/bjc.2014.54. Epub 2014 Feb 11.


T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.

Stirnweiss A, Hartig R, Gieseler S, Lindquist JA, Reichardt P, Philipsen L, Simeoni L, Poltorak M, Merten C, Zuschratter W, Prokazov Y, Paster W, Stockinger H, Harder T, Gunzer M, Schraven B.

Sci Signal. 2013 Feb 19;6(263):ra13. doi: 10.1126/scisignal.2003607.


Novel BRD4-NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma.

Thompson-Wicking K, Francis RW, Stirnweiss A, Ferrari E, Welch MD, Baker E, Murch AR, Gout AM, Carter KW, Charles AK, Phillips MB, Kees UR, Beesley AH.

Oncogene. 2013 Sep 26;32(39):4664-74. doi: 10.1038/onc.2012.487. Epub 2012 Nov 5.


IFN regulatory factor-1 bypasses IFN-mediated antiviral effects through viperin gene induction.

Stirnweiss A, Ksienzyk A, Klages K, Rand U, Grashoff M, Hauser H, Kröger A.

J Immunol. 2010 May 1;184(9):5179-85. doi: 10.4049/jimmunol.0902264. Epub 2010 Mar 22.


Tumor suppression by IFN regulatory factor-1 is mediated by transcriptional down-regulation of cyclin D1.

Kröger A, Stirnweiss A, Pulverer JE, Klages K, Grashoff M, Reimann J, Hauser H.

Cancer Res. 2007 Apr 1;67(7):2972-81.

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