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Items: 31

1.

Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.

Randzavola LO, Strege K, Juzans M, Asano Y, Stinchcombe JC, Gawden-Bone CM, Seaman MN, Kuijpers TW, Griffiths GM.

J Clin Invest. 2019 Nov 11. pii: 129388. doi: 10.1172/JCI129388. [Epub ahead of print]

2.

Inducible T Cell Kinase Regulates the Acquisition of Cytolytic Capacity and Degranulation in CD8+ CTLs.

Kapnick SM, Stinchcombe JC, Griffiths GM, Schwartzberg PL.

J Immunol. 2017 Apr 1;198(7):2699-2711. doi: 10.4049/jimmunol.1601202. Epub 2017 Feb 17.

3.

The cytotoxic T lymphocyte immune synapse at a glance.

Dieckmann NM, Frazer GL, Asano Y, Stinchcombe JC, Griffiths GM.

J Cell Sci. 2016 Aug 1;129(15):2881-6. doi: 10.1242/jcs.186205. Review.

4.

Mother Centriole Distal Appendages Mediate Centrosome Docking at the Immunological Synapse and Reveal Mechanistic Parallels with Ciliogenesis.

Stinchcombe JC, Randzavola LO, Angus KL, Mantell JM, Verkade P, Griffiths GM.

Curr Biol. 2015 Dec 21;25(24):3239-44. doi: 10.1016/j.cub.2015.10.028. Epub 2015 Dec 5.

5.

Actin depletion initiates events leading to granule secretion at the immunological synapse.

Ritter AT, Asano Y, Stinchcombe JC, Dieckmann NM, Chen BC, Gawden-Bone C, van Engelenburg S, Legant W, Gao L, Davidson MW, Betzig E, Lippincott-Schwartz J, Griffiths GM.

Immunity. 2015 May 19;42(5):864-76. doi: 10.1016/j.immuni.2015.04.013.

6.

Communication, the centrosome and the immunological synapse.

Stinchcombe JC, Griffiths GM.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 5;369(1650). pii: 20130463. doi: 10.1098/rstb.2013.0463. Review.

7.

Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL.

Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM.

Elife. 2014 Mar 4;3:e01310. doi: 10.7554/eLife.01310.

8.

Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation.

Lui-Roberts WW, Stinchcombe JC, Ritter AT, Akhmanova A, Karakesisoglou I, Griffiths GM.

Eur J Immunol. 2012 Aug;42(8):2132-41. doi: 10.1002/eji.201242525.

9.

Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems.

Stinchcombe JC, Salio M, Cerundolo V, Pende D, Arico M, Griffiths GM.

BMC Biol. 2011 Jun 28;9:45. doi: 10.1186/1741-7007-9-45.

10.

Centrosome docking at the immunological synapse is controlled by Lck signaling.

Tsun A, Qureshi I, Stinchcombe JC, Jenkins MR, de la Roche M, Kleczkowska J, Zamoyska R, Griffiths GM.

J Cell Biol. 2011 Feb 21;192(4):663-74. doi: 10.1083/jcb.201008140.

11.

The immunological synapse: a focal point for endocytosis and exocytosis.

Griffiths GM, Tsun A, Stinchcombe JC.

J Cell Biol. 2010 May 3;189(3):399-406. doi: 10.1083/jcb.201002027. Review.

12.

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse.

Jenkins MR, Tsun A, Stinchcombe JC, Griffiths GM.

Immunity. 2009 Oct 16;31(4):621-31. doi: 10.1016/j.immuni.2009.08.024.

13.

Secretory mechanisms in cell-mediated cytotoxicity.

Stinchcombe JC, Griffiths GM.

Annu Rev Cell Dev Biol. 2007;23:495-517. Review.

PMID:
17506701
14.

Centrosome polarization delivers secretory granules to the immunological synapse.

Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM.

Nature. 2006 Sep 28;443(7110):462-5. Erratum in: Nature. 2006 Nov 9;444(7116):236.

PMID:
17006514
15.

Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis.

Santoro A, Cannella S, Bossi G, Gallo F, Trizzino A, Pende D, Dieli F, Bruno G, Stinchcombe JC, Micalizzi C, De Fusco C, Danesino C, Moretta L, Notarangelo LD, Griffiths GM, Aricò M.

J Med Genet. 2006 Dec;43(12):953-60. Epub 2006 Jul 6.

16.

The role of the secretory immunological synapse in killing by CD8+ CTL.

Stinchcombe JC, Griffiths GM.

Semin Immunol. 2003 Dec;15(6):301-5. Review.

PMID:
15001168
17.

Adaptor protein 3-dependent microtubule-mediated movement of lytic granules to the immunological synapse.

Clark RH, Stinchcombe JC, Day A, Blott E, Booth S, Bossi G, Hamblin T, Davies EG, Griffiths GM.

Nat Immunol. 2003 Nov;4(11):1111-20. Epub 2003 Oct 19.

PMID:
14566336
18.

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton.

Igakura T, Stinchcombe JC, Goon PK, Taylor GP, Weber JN, Griffiths GM, Tanaka Y, Osame M, Bangham CR.

Science. 2003 Mar 14;299(5613):1713-6. Epub 2003 Feb 13.

19.

The immunological synapse of CTL contains a secretory domain and membrane bridges.

Stinchcombe JC, Bossi G, Booth S, Griffiths GM.

Immunity. 2001 Nov;15(5):751-61.

20.

Normal and abnormal secretion by haemopoietic cells.

Stinchcombe JC, Griffiths GM.

Immunology. 2001 May;103(1):10-6. Review.

21.

Rab27a is required for regulated secretion in cytotoxic T lymphocytes.

Stinchcombe JC, Barral DC, Mules EH, Booth S, Hume AN, Machesky LM, Seabra MC, Griffiths GM.

J Cell Biol. 2001 Feb 19;152(4):825-34.

22.
23.

Analysis of the lysosomal storage disease Chediak-Higashi syndrome.

Ward DM, Griffiths GM, Stinchcombe JC, Kaplan J.

Traffic. 2000 Nov;1(11):816-22. Review.

24.

Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.

Hanon E, Stinchcombe JC, Saito M, Asquith BE, Taylor GP, Tanaka Y, Weber JN, Griffiths GM, Bangham CR.

Immunity. 2000 Nov;13(5):657-64.

25.

Sorting out the multiple roles of Fas ligand.

Bossi G, Stinchcombe JC, Page LJ, Griffiths GM.

Eur J Cell Biol. 2000 Aug;79(8):539-43. Review.

PMID:
11001490
26.

Regulated secretion from hemopoietic cells.

Stinchcombe JC, Griffiths GM.

J Cell Biol. 1999 Oct 4;147(1):1-6. Review. No abstract available.

27.

Anterograde and retrograde traffic between the rough endoplasmic reticulum and the Golgi complex.

Stinchcombe JC, Nomoto H, Cutler DF, Hopkins CR.

J Cell Biol. 1995 Dec;131(6 Pt 1):1387-401.

28.

Brefeldin A inhibits the formation of constitutive secretory vesicles and immature secretory granules from the trans-Golgi network.

Rosa P, Barr FA, Stinchcombe JC, Binacchi C, Huttner WB.

Eur J Cell Biol. 1992 Dec;59(2):265-74.

PMID:
1493791
29.

Biogenesis of secretory granules.

Tooze SA, Stinchcombe JC.

Semin Cell Biol. 1992 Oct;3(5):357-66. Review.

PMID:
1457778
30.

Two membrane-bound forms of tyrosylprotein sulfotransferase as revealed by phase partitioning in Triton X-114.

Niehrs C, Stinchcombe JC, Huttner WB.

Eur J Cell Biol. 1992 Jun;58(1):35-43.

PMID:
1644064
31.

What the granins tell us about the formation of secretory granules in neuroendocrine cells.

Chanat E, Pimplikar SW, Stinchcombe JC, Huttner WB.

Cell Biophys. 1991 Oct-Dec;19(1-3):85-91. Review. No abstract available.

PMID:
1726891

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