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Items: 35

1.

Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma.

Hill LA, Vassiliadi DA, Dimopoulou I, Anderson AJ, Boyle LD, Kilgour AHM, Stimson RH, Machado Y, Overall CM, Walker BR, Lewis JG, Hammond GL.

J Endocrinol. 2019 Jan 1;240(1):27-39. doi: 10.1530/JOE-18-0479.

2.

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides.

Weir G, Ramage LE, Akyol M, Rhodes JK, Kyle CJ, Fletcher AM, Craven TH, Wakelin SJ, Drake AJ, Gregoriades ML, Ashton C, Weir N, van Beek EJR, Karpe F, Walker BR, Stimson RH.

Cell Metab. 2018 Jun 5;27(6):1348-1355.e4. doi: 10.1016/j.cmet.2018.04.020. Epub 2018 May 24.

3.

Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia.

Alwashih MA, Watson DG, Andrew R, Stimson RH, Alossaimi M, Blackburn G, Walker BR.

Sci Rep. 2017 Dec 6;7(1):17092. doi: 10.1038/s41598-017-17220-5.

4.

Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans.

Alwashih MA, Stimson RH, Andrew R, Walker BR, Watson DG.

Sci Rep. 2017 Sep 13;7(1):11488. doi: 10.1038/s41598-017-10200-9.

5.

Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Björkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR.

Sci Rep. 2017 Sep 6;7(1):10633. doi: 10.1038/s41598-017-10410-1.

6.

Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism.

Thompson AA, Dickinson RS, Murphy F, Thomson JP, Marriott HM, Tavares A, Willson J, Williams L, Lewis A, Mirchandani A, Dos Santos Coelho P, Doherty C, Ryan E, Watts E, Morton NM, Forbes S, Stimson RH, Hameed AG, Arnold N, Preston JA, Lawrie A, Finisguerra V, Mazzone M, Sadiku P, Goveia J, Taverna F, Carmeliet P, Foster SJ, Chilvers ER, Cowburn AS, Dockrell DH, Johnson RS, Meehan RR, Whyte MK, Walmsley SR.

Sci Immunol. 2017 Feb 10;2(8). pii: eaal2861. doi: 10.1126/sciimmunol.aal2861.

7.

Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.

Stimson RH, Anderson AJ, Ramage LE, Macfarlane DP, de Beaux AC, Mole DJ, Andrew R, Walker BR.

Diabetes Obes Metab. 2017 Jun;19(6):883-891. doi: 10.1111/dom.12899. Epub 2017 Mar 28.

8.

ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.

Nixon M, Mackenzie SD, Taylor AI, Homer NZ, Livingstone DE, Mouras R, Morgan RA, Mole DJ, Stimson RH, Reynolds RM, Elfick AP, Andrew R, Walker BR.

Sci Transl Med. 2016 Aug 17;8(352):352ra109. doi: 10.1126/scitranslmed.aaf9074.

PMID:
27535620
9.

Flash Glucose Monitoring Improves Outcomes in a Type 1 Diabetes Clinic.

Dover AR, Stimson RH, Zammitt NN, Gibb FW.

J Diabetes Sci Technol. 2017 Mar;11(2):442-443. doi: 10.1177/1932296816661560. Epub 2016 Jul 28. No abstract available.

10.

Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus.

Anderson AJ, Andrew R, Homer NZ, Jones GC, Smith K, Livingstone DE, Walker BR, Stimson RH.

J Clin Endocrinol Metab. 2016 Oct;101(10):3787-3793. Epub 2016 Jul 26.

11.

Glucocorticoids Acutely Increase Brown Adipose Tissue Activity in Humans, Revealing Species-Specific Differences in UCP-1 Regulation.

Ramage LE, Akyol M, Fletcher AM, Forsythe J, Nixon M, Carter RN, van Beek EJ, Morton NM, Walker BR, Stimson RH.

Cell Metab. 2016 Jul 12;24(1):130-41. doi: 10.1016/j.cmet.2016.06.011.

12.

Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women.

Stomby A, Simonyte K, Mellberg C, Ryberg M, Stimson RH, Larsson C, Lindahl B, Andrew R, Walker BR, Olsson T.

Int J Obes (Lond). 2015 May;39(5):814-9. doi: 10.1038/ijo.2014.188. Epub 2014 Oct 28.

PMID:
25349058
13.

Relationship between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE).

Han TS, Conway GS, Willis DS, Krone N, Rees DA, Stimson RH, Arlt W, Walker BR, Ross RJ; United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE).

J Clin Endocrinol Metab. 2014 Aug;99(8):E1547-55. doi: 10.1210/jc.2014-1486. Epub 2014 May 30.

PMID:
24878054
14.

Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women.

Goedecke JH, Chorell E, Livingstone DE, Stimson RH, Hayes P, Adams K, Dave JA, Victor H, Levitt NS, Kahn SE, Seckl JR, Walker BR, Olsson T.

Int J Obes (Lond). 2015 Feb;39(2):303-11. doi: 10.1038/ijo.2014.94. Epub 2014 May 20.

PMID:
24854429
15.

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source.

Chau YY, Bandiera R, Serrels A, Martínez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, Hastie N.

Nat Cell Biol. 2014 Apr;16(4):367-75. doi: 10.1038/ncb2922. Epub 2014 Mar 9.

16.

The postprandial rise in plasma cortisol in men is mediated by macronutrient-specific stimulation of adrenal and extra-adrenal cortisol production.

Stimson RH, Mohd-Shukri NA, Bolton JL, Andrew R, Reynolds RM, Walker BR.

J Clin Endocrinol Metab. 2014 Jan;99(1):160-168. doi: 10.1210/jc.2013-2307. Epub 2013 Dec 20.

17.

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Stimson RH, Walker BR.

Horm Mol Biol Clin Investig. 2013 Sep;15(2):37-48. doi: 10.1515/hmbci-2013-0015. Review.

PMID:
25436731
18.

Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

Han TS, Krone N, Willis DS, Conway GS, Hahner S, Rees DA, Stimson RH, Walker BR, Arlt W, Ross RJ; United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

Eur J Endocrinol. 2013 May 3;168(6):887-93. doi: 10.1530/EJE-13-0128. Print 2013 Jun.

19.

Genotype-phenotype correlation in 153 adult patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: analysis of the United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) cohort.

Krone N, Rose IT, Willis DS, Hodson J, Wild SH, Doherty EJ, Hahner S, Parajes S, Stimson RH, Han TS, Carroll PV, Conway GS, Walker BR, MacDonald F, Ross RJ, Arlt W; United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

J Clin Endocrinol Metab. 2013 Feb;98(2):E346-54. doi: 10.1210/jc.2012-3343. Epub 2013 Jan 21.

20.

Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia.

Han TS, Stimson RH, Rees DA, Krone N, Willis DS, Conway GS, Arlt W, Walker BR, Ross RJ; United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

Clin Endocrinol (Oxf). 2013 Feb;78(2):197-203. doi: 10.1111/cen.12045.

PMID:
22998134
21.

Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo.

Hughes KA, Manolopoulos KN, Iqbal J, Cruden NL, Stimson RH, Reynolds RM, Newby DE, Andrew R, Karpe F, Walker BR.

Diabetes. 2012 Jun;61(6):1357-64. doi: 10.2337/db11-1345. Epub 2012 Apr 17.

22.

Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization.

Nixon M, Wake DJ, Livingstone DE, Stimson RH, Esteves CL, Seckl JR, Chapman KE, Andrew R, Walker BR.

Diabetes. 2012 Apr;61(4):790-6. doi: 10.2337/db11-0931. Epub 2012 Feb 22.

23.

Reduced gluteal expression of adipogenic and lipogenic genes in Black South African women is associated with obesity-related insulin resistance.

Goedecke JH, Evans J, Keswell D, Stimson RH, Livingstone DE, Hayes P, Adams K, Dave JA, Victor H, Levitt NS, Lambert EV, Walker BR, Seckl JR, Olsson T, Kahn SE.

J Clin Endocrinol Metab. 2011 Dec;96(12):E2029-33. doi: 10.1210/jc.2011-1576. Epub 2011 Sep 28.

24.

A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome.

Gambineri A, Tomassoni F, Munarini A, Stimson RH, Mioni R, Pagotto U, Chapman KE, Andrew R, Mantovani V, Pasquali R, Walker BR.

Eur J Endocrinol. 2011 Aug;165(2):283-92. doi: 10.1530/EJE-11-0091. Epub 2011 May 27.

PMID:
21622477
25.

Increased whole-body and sustained liver cortisol regeneration by 11beta-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition.

Stimson RH, Andrew R, McAvoy NC, Tripathi D, Hayes PC, Walker BR.

Diabetes. 2011 Mar;60(3):720-5. doi: 10.2337/db10-0726. Epub 2011 Jan 24.

26.

Health status of adults with congenital adrenal hyperplasia: a cohort study of 203 patients.

Arlt W, Willis DS, Wild SH, Krone N, Doherty EJ, Hahner S, Han TS, Carroll PV, Conway GS, Rees DA, Stimson RH, Walker BR, Connell JM, Ross RJ; United Kingdom Congenital Adrenal Hyperplasia Adult Study Executive (CaHASE).

J Clin Endocrinol Metab. 2010 Nov;95(11):5110-21. doi: 10.1210/jc.2010-0917. Epub 2010 Aug 18.

27.

Effects of proportions of dietary macronutrients on glucocorticoid metabolism in diet-induced obesity in rats.

Stimson RH, Lobley GE, Maraki I, Morton NM, Andrew R, Walker BR.

PLoS One. 2010 Jan 19;5(1):e8779. doi: 10.1371/journal.pone.0008779.

28.

Lack of regulation of 11beta-hydroxysteroid dehydrogenase type 1 during short-term manipulation of GH in patients with hypopituitarism.

Sigurjonsdottir HA, Andrew R, Stimson RH, Johannsson G, Walker BR.

Eur J Endocrinol. 2009 Sep;161(3):375-80. doi: 10.1530/EJE-09-0315. Epub 2009 Jun 23.

29.

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

Stimson RH, Andersson J, Andrew R, Redhead DN, Karpe F, Hayes PC, Olsson T, Walker BR.

Diabetes. 2009 Jan;58(1):46-53. doi: 10.2337/db08-0969. Epub 2008 Oct 13.

30.

Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Stimson RH, Walker BR.

Minerva Endocrinol. 2007 Sep;32(3):141-59. Review.

PMID:
17912154
31.

Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men.

Stimson RH, Johnstone AM, Homer NZ, Wake DJ, Morton NM, Andrew R, Lobley GE, Walker BR.

J Clin Endocrinol Metab. 2007 Nov;92(11):4480-4. Epub 2007 Sep 4.

PMID:
17785367
32.

Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.

Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.

J Clin Endocrinol Metab. 2007 May;92(5):1848-56. Epub 2007 Feb 27.

PMID:
17327378
33.

The diagnostic value of anti-neutrophil cytoplasmic antibody testing in a routine clinical setting.

McLaren JS, Stimson RH, McRorie ER, Coia JE, Luqmani RA.

QJM. 2001 Nov;94(11):615-21.

PMID:
11704691
34.

The use of negative indexes of health to evaluate quality of care in a primary-care group practice.

Heineken PA, Charles G, Stimson DH, Wenell C, Stimson RH.

Med Care. 1985 Mar;23(3):198-208.

PMID:
3982103
35.

Health services research and health policy issues.

Stimson DH, Stimson RH.

Health Serv Res. 1976 Fall;11(3):221-6. No abstract available.

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