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Items: 19

1.

PseudoGTPase domains in p190RhoGAP proteins: a mini-review.

Stiegler AL, Boggon TJ.

Biochem Soc Trans. 2018 Dec 4. pii: BST20180481. doi: 10.1042/BST20180481. [Epub ahead of print] Review.

PMID:
30514771
2.

The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase.

Stiegler AL, Boggon TJ.

Structure. 2018 Nov 6;26(11):1451-1461.e4. doi: 10.1016/j.str.2018.07.015. Epub 2018 Aug 30.

PMID:
30174148
3.

p190RhoGAP proteins contain pseudoGTPase domains.

Stiegler AL, Boggon TJ.

Nat Commun. 2017 Sep 11;8(1):506. doi: 10.1038/s41467-017-00483-x.

4.

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition.

Zhao S, Bellone S, Lopez S, Thakral D, Schwab C, English DP, Black J, Cocco E, Choi J, Zammataro L, Predolini F, Bonazzoli E, Bi M, Buza N, Hui P, Wong S, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Odicino F, Pecorelli S, Donzelli C, Ardighieri L, Facchetti F, Falchetti M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Mane S, Angioli R, Terranova C, Quick CM, Edraki B, Bilgüvar K, Lee M, Choi M, Stiegler AL, Boggon TJ, Schlessinger J, Lifton RP, Santin AD.

Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12238-12243. Epub 2016 Oct 10.

5.

Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension.

Vilarinho S, Sari S, Yilmaz G, Stiegler AL, Boggon TJ, Jain D, Akyol G, Dalgic B, Günel M, Lifton RP.

Hepatology. 2016 Jun;63(6):1977-86. doi: 10.1002/hep.28499. Epub 2016 Mar 31.

6.

Structural basis for the disruption of the cerebral cavernous malformations 2 (CCM2) interaction with Krev interaction trapped 1 (KRIT1) by disease-associated mutations.

Fisher OS, Liu W, Zhang R, Stiegler AL, Ghedia S, Weber JL, Boggon TJ.

J Biol Chem. 2015 Jan 30;290(5):2842-53. doi: 10.1074/jbc.M114.616433. Epub 2014 Dec 18.

7.

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation.

Romberg N, Al Moussawi K, Nelson-Williams C, Stiegler AL, Loring E, Choi M, Overton J, Meffre E, Khokha MK, Huttner AJ, West B, Podoltsev NA, Boggon TJ, Kazmierczak BI, Lifton RP.

Nat Genet. 2014 Oct;46(10):1135-1139. doi: 10.1038/ng.3066. Epub 2014 Sep 14.

8.

Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation.

Huet-Calderwood C, Brahme NN, Kumar N, Stiegler AL, Raghavan S, Boggon TJ, Calderwood DA.

J Cell Sci. 2014 Oct 1;127(Pt 19):4308-21. doi: 10.1242/jcs.155879. Epub 2014 Aug 1.

9.

Structural determinants for binding of sorting nexin 17 (SNX17) to the cytoplasmic adaptor protein Krev interaction trapped 1 (KRIT1).

Stiegler AL, Zhang R, Liu W, Boggon TJ.

J Biol Chem. 2014 Sep 5;289(36):25362-73. doi: 10.1074/jbc.M114.584011. Epub 2014 Jul 24.

10.

Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors.

Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T.

Pigment Cell Melanoma Res. 2014 Mar;27(2):253-62. doi: 10.1111/pcmr.12197. Epub 2014 Jan 6.

11.

Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP.

Cell Metab. 2013 Nov 5;18(5):660-71. doi: 10.1016/j.cmet.2013.10.005.

12.

Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex.

Stiegler AL, Grant TD, Luft JR, Calderwood DA, Snell EH, Boggon TJ.

PLoS One. 2013;8(1):e55591. doi: 10.1371/journal.pone.0055591. Epub 2013 Jan 31.

13.

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma.

Zhao S, Choi M, Overton JD, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N, Hui P, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Carrara L, Pecorelli S, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Stiegler AL, Mane S, Boggon TJ, Schlessinger J, Lifton RP, Santin AD.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2916-21. doi: 10.1073/pnas.1222577110. Epub 2013 Jan 28.

14.

Structural basis for paxillin binding and focal adhesion targeting of β-parvin.

Stiegler AL, Draheim KM, Li X, Chayen NE, Calderwood DA, Boggon TJ.

J Biol Chem. 2012 Sep 21;287(39):32566-77. Epub 2012 Aug 6.

15.

EGFR-mutated lung cancer: a paradigm of molecular oncology.

Zhang Z, Stiegler AL, Boggon TJ, Kobayashi S, Halmos B.

Oncotarget. 2010 Nov;1(7):497-514. Review.

16.

Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase.

Chiswell BP, Stiegler AL, Razinia Z, Nalibotski E, Boggon TJ, Calderwood DA.

J Struct Biol. 2010 Apr;170(1):157-63. doi: 10.1016/j.jsb.2009.12.002. Epub 2009 Dec 4.

17.

Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK.

Stiegler AL, Burden SJ, Hubbard SR.

J Mol Biol. 2009 Oct 16;393(1):1-9. doi: 10.1016/j.jmb.2009.07.091. Epub 2009 Aug 4.

18.

Lrp4 is a receptor for Agrin and forms a complex with MuSK.

Kim N, Stiegler AL, Cameron TO, Hallock PT, Gomez AM, Huang JH, Hubbard SR, Dustin ML, Burden SJ.

Cell. 2008 Oct 17;135(2):334-42. doi: 10.1016/j.cell.2008.10.002. Epub 2008 Oct 9.

19.

Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK.

Stiegler AL, Burden SJ, Hubbard SR.

J Mol Biol. 2006 Dec 1;364(3):424-33. Epub 2006 Sep 12.

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