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Items: 1 to 50 of 123

1.

Droplet Core Intermolecular Interactions and Block Copolymer Composition Heavily Influence Oil-In-Water Nanoemulsion Stability.

Barres AR, Molugu SK, Stewart PL, Mecozzi S.

Langmuir. 2019 Sep 18. doi: 10.1021/acs.langmuir.9b01519. [Epub ahead of print]

PMID:
31532686
2.

Contrast enhanced ultrasound imaging by nature-inspired ultrastable echogenic nanobubbles.

de Leon A, Perera R, Hernandez C, Cooley M, Jung O, Jeganathan S, Abenojar E, Fishbein G, Sojahrood AJ, Emerson CC, Stewart PL, Kolios MC, Exner AA.

Nanoscale. 2019 Sep 7;11(33):15647-15658. doi: 10.1039/c9nr04828f. Epub 2019 Aug 13.

PMID:
31408083
3.

Cryo-Electron Microscopy Structure of an Acinetobacter baumannii Multidrug Efflux Pump.

Su CC, Morgan CE, Kambakam S, Rajavel M, Scott H, Huang W, Emerson CC, Taylor DJ, Stewart PL, Bonomo RA, Yu EW.

MBio. 2019 Jul 2;10(4). pii: e01295-19. doi: 10.1128/mBio.01295-19.

4.

Freeze-Drying To Produce Efficacious CPMV Virus-like Particles.

Zheng Y, Lee PW, Wang C, Thomas LD, Stewart PL, Steinmetz NF, Pokorski JK.

Nano Lett. 2019 Mar 13;19(3):2099-2105. doi: 10.1021/acs.nanolett.9b00300. Epub 2019 Feb 25.

PMID:
30801195
5.

The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition.

Gulati NM, Pitek AS, Czapar AE, Stewart PL, Steinmetz NF.

J Mater Chem B. 2018 Apr 21;6(15):2204-2216. doi: 10.1039/C7TB03106H. Epub 2018 Feb 27.

6.

Engineering of a Polydisperse Small Heat-Shock Protein Reveals Conserved Motifs of Oligomer Plasticity.

Mishra S, Chandler SA, Williams D, Claxton DP, Koteiche HA, Stewart PL, Benesch JLP, Mchaourab HS.

Structure. 2018 Aug 7;26(8):1116-1126.e4. doi: 10.1016/j.str.2018.05.015. Epub 2018 Jul 5.

7.

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.

Gulati S, Jin H, Masuho I, Orban T, Cai Y, Pardon E, Martemyanov KA, Kiser PD, Stewart PL, Ford CP, Steyaert J, Palczewski K.

Nat Commun. 2018 May 18;9(1):1996. doi: 10.1038/s41467-018-04432-0.

8.

A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.

Chen Y, Chen Y, Jastrzebska B, Golczak M, Gulati S, Tang H, Seibel W, Li X, Jin H, Han Y, Gao S, Zhang J, Liu X, Heidari-Torkabadi H, Stewart PL, Harte WE, Tochtrop GP, Palczewski K.

Nat Commun. 2018 May 17;9(1):1976. doi: 10.1038/s41467-018-04261-1.

9.

Bioinspired Shielding Strategies for Nanoparticle Drug Delivery Applications.

Gulati NM, Stewart PL, Steinmetz NF.

Mol Pharm. 2018 Aug 6;15(8):2900-2909. doi: 10.1021/acs.molpharmaceut.8b00292. Epub 2018 May 15. Review.

10.

Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor.

Gorelenkova Miller O, Cole KS, Emerson CC, Allimuthu D, Golczak M, Stewart PL, Weerapana E, Adams DJ, Mieyal JJ.

PLoS One. 2017 Nov 20;12(11):e0187991. doi: 10.1371/journal.pone.0187991. eCollection 2017.

11.

Cryo-EM Visualization of Lipid and Polymer-Stabilized Perfluorocarbon Gas Nanobubbles - A Step Towards Nanobubble Mediated Drug Delivery.

Hernandez C, Gulati S, Fioravanti G, Stewart PL, Exner AA.

Sci Rep. 2017 Oct 18;7(1):13517. doi: 10.1038/s41598-017-13741-1.

12.

Elongated Plant Virus-Based Nanoparticles for Enhanced Delivery of Thrombolytic Therapies.

Pitek AS, Wang Y, Gulati S, Gao H, Stewart PL, Simon DI, Steinmetz NF.

Mol Pharm. 2017 Nov 6;14(11):3815-3823. doi: 10.1021/acs.molpharmaceut.7b00559. Epub 2017 Sep 26.

13.

Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism.

Gulati S, Jastrzebska B, Banerjee S, Placeres ÁL, Miszta P, Gao S, Gunderson K, Tochtrop GP, Filipek S, Katayama K, Kiser PD, Mogi M, Stewart PL, Palczewski K.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2608-E2615. doi: 10.1073/pnas.1617446114. Epub 2017 Mar 13.

14.

Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates.

Lee PW, Isarov SA, Wallat JD, Molugu SK, Shukla S, Sun JE, Zhang J, Zheng Y, Lucius Dougherty M, Konkolewicz D, Stewart PL, Steinmetz NF, Hore MJ, Pokorski JK.

J Am Chem Soc. 2017 Mar 8;139(9):3312-3315. doi: 10.1021/jacs.6b11643. Epub 2017 Jan 25.

15.

Cryo-electron tomography investigation of serum albumin-camouflaged tobacco mosaic virus nanoparticles.

Gulati NM, Pitek AS, Steinmetz NF, Stewart PL.

Nanoscale. 2017 Mar 9;9(10):3408-3415. doi: 10.1039/c6nr06948g.

16.

Insights into Adenovirus Uncoating from Interactions with Integrins and Mediators of Host Immunity.

Nemerow GR, Stewart PL.

Viruses. 2016 Dec 21;8(12). pii: E337. doi: 10.3390/v8120337. Review.

17.

Cryo-electron microscopy and cryo-electron tomography of nanoparticles.

Stewart PL.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Mar;9(2). doi: 10.1002/wnan.1417. Epub 2016 Jun 23. Review.

PMID:
27339510
18.

Multiple Administrations of Viral Nanoparticles Alter in Vivo Behavior-Insights from Intravital Microscopy.

Shukla S, Dorand RD, Myers JT, Woods SE, Gulati NM, Stewart PL, Commandeur U, Huang AY, Steinmetz NF.

ACS Biomater Sci Eng. 2016 May 9;2(5):829-837. doi: 10.1021/acsbiomaterials.6b00060. Epub 2016 Mar 30.

19.

Bioengineering of Tobacco Mosaic Virus to Create a Non-Infectious Positive Control for Ebola Diagnostic Assays.

Lam P, Gulati NM, Stewart PL, Keri RA, Steinmetz NF.

Sci Rep. 2016 Mar 31;6:23803. doi: 10.1038/srep23803.

20.

An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device.

Hofmann L, Gulati S, Sears A, Stewart PL, Palczewski K.

Anal Biochem. 2016 Apr 15;499:63-65. doi: 10.1016/j.ab.2016.01.016. Epub 2016 Feb 4.

21.

Silica-coated Gd(DOTA)-loaded protein nanoparticles enable magnetic resonance imaging of macrophages.

Bruckman MA, Randolph LN, Gulati NM, Stewart PL, Steinmetz NF.

J Mater Chem B. 2015 Oct 1;3(38):7503-7510. Epub 2015 Jul 22.

22.

In Situ Characterization of Binary Mixed Polymer Brush-Grafted Silica Nanoparticles in Aqueous and Organic Solvents by Cryo-Electron Tomography.

Fox TL, Tang S, Horton JM, Holdaway HA, Zhao B, Zhu L, Stewart PL.

Langmuir. 2015 Aug 11;31(31):8680-8. doi: 10.1021/acs.langmuir.5b01739. Epub 2015 Jul 28.

PMID:
26174179
23.

Environmentally responsive self-assembly of mixed poly(tert-butyl acrylate)-polystyrene brush-grafted silica nanoparticles in selective polymer matrices.

Tang S, Fox TL, Lo TY, Horton JM, Ho RM, Zhao B, Stewart PL, Zhu L.

Soft Matter. 2015 Jul 21;11(27):5501-12. doi: 10.1039/c5sm00193e.

PMID:
26061172
24.

Crystallization of proteins from crude bovine rod outer segments.

Baker BY, Gulati S, Shi W, Wang B, Stewart PL, Palczewski K.

Methods Enzymol. 2015;557:439-58. doi: 10.1016/bs.mie.2014.11.045. Epub 2015 Mar 17.

25.

Detection and imaging of aggressive cancer cells using an epidermal growth factor receptor (EGFR)-targeted filamentous plant virus-based nanoparticle.

Chariou PL, Lee KL, Wen AM, Gulati NM, Stewart PL, Steinmetz NF.

Bioconjug Chem. 2015 Feb 18;26(2):262-269. doi: 10.1021/bc500545z. Epub 2015 Feb 5.

26.

Structural insight into the assembly of TRPV channels.

Huynh KW, Cohen MR, Chakrapani S, Holdaway HA, Stewart PL, Moiseenkova-Bell VY.

Structure. 2014 Feb 4;22(2):260-8. doi: 10.1016/j.str.2013.11.008. Epub 2013 Dec 26.

27.

CryoEM and image sorting for flexible protein/DNA complexes.

Villarreal SA, Stewart PL.

J Struct Biol. 2014 Jul;187(1):76-83. doi: 10.1016/j.jsb.2013.12.002. Epub 2013 Dec 9.

PMID:
24333094
28.

Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody.

Aiyegbo MS, Eli IM, Spiller BW, Williams DR, Kim R, Lee DE, Liu T, Li S, Stewart PL, Crowe JE Jr.

J Virol. 2014 Jan;88(1):469-76. doi: 10.1128/JVI.01665-13. Epub 2013 Oct 23.

29.

Coagulation factor binding orientation and dimerization may influence infectivity of adenovirus-coagulation factor complexes.

Irons EE, Flatt JW, Doronin K, Fox TL, Acchione M, Stewart PL, Shayakhmetov DM.

J Virol. 2013 Sep;87(17):9610-9. doi: 10.1128/JVI.01070-13. Epub 2013 Jun 26.

30.

CryoEM and molecular dynamics of the circadian KaiB-KaiC complex indicates that KaiB monomers interact with KaiC and block ATP binding clefts.

Villarreal SA, Pattanayek R, Williams DR, Mori T, Qin X, Johnson CH, Egli M, Stewart PL.

J Mol Biol. 2013 Sep 23;425(18):3311-24. doi: 10.1016/j.jmb.2013.06.018. Epub 2013 Jun 22.

31.

Barley stripe mosaic virus: structure and relationship to the tobamoviruses.

Kendall A, Williams D, Bian W, Stewart PL, Stubbs G.

Virology. 2013 Sep 1;443(2):265-70. doi: 10.1016/j.virol.2013.05.010. Epub 2013 May 29.

32.

Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore.

Aiyegbo MS, Sapparapu G, Spiller BW, Eli IM, Williams DR, Kim R, Lee DE, Liu T, Li S, Woods VL Jr, Nannemann DP, Meiler J, Stewart PL, Crowe JE Jr.

PLoS One. 2013 May 9;8(5):e61101. doi: 10.1371/journal.pone.0061101. Print 2013.

33.

An intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5.

Flatt JW, Kim R, Smith JG, Nemerow GR, Stewart PL.

PLoS One. 2013 Apr 19;8(4):e61571. doi: 10.1371/journal.pone.0061571. Print 2013.

34.

Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding.

Shi J, Koteiche HA, McDonald ET, Fox TL, Stewart PL, McHaourab HS.

J Biol Chem. 2013 Feb 15;288(7):4819-30. doi: 10.1074/jbc.M112.388132. Epub 2012 Dec 30.

35.

Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs.

Lindert S, Stewart PL, Meiler J.

Comput Biol Chem. 2013 Feb;42:1-4. doi: 10.1016/j.compbiolchem.2012.11.001. Epub 2012 Nov 19.

36.

A common structure for the potexviruses.

Kendall A, Bian W, Maris A, Azzo C, Groom J, Williams D, Shi J, Stewart PL, Wall JS, Stubbs G.

Virology. 2013 Feb 5;436(1):173-8. doi: 10.1016/j.virol.2012.11.008. Epub 2012 Dec 11.

37.

CryoEM visualization of an adenovirus capsid-incorporated HIV antigen.

Flatt JW, Fox TL, Makarova N, Blackwell JL, Dmitriev IP, Kashentseva EA, Curiel DT, Stewart PL.

PLoS One. 2012;7(11):e49607. doi: 10.1371/journal.pone.0049607. Epub 2012 Nov 14.

38.

Coagulation factor X activates innate immunity to human species C adenovirus.

Doronin K, Flatt JW, Di Paolo NC, Khare R, Kalyuzhniy O, Acchione M, Sumida JP, Ohto U, Shimizu T, Akashi-Takamura S, Miyake K, MacDonald JW, Bammler TK, Beyer RP, Farin FM, Stewart PL, Shayakhmetov DM.

Science. 2012 Nov 9;338(6108):795-8. doi: 10.1126/science.1226625. Epub 2012 Sep 27.

39.

Structure of human adenovirus.

Nemerow GR, Stewart PL, Reddy VS.

Curr Opin Virol. 2012 Apr;2(2):115-21. doi: 10.1016/j.coviro.2011.12.008. Epub 2012 Jan 18. Review.

40.

EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps.

Lindert S, Alexander N, Wötzel N, Karakaş M, Stewart PL, Meiler J.

Structure. 2012 Mar 7;20(3):464-78. doi: 10.1016/j.str.2012.01.023.

41.

Ab initio protein modeling into CryoEM density maps using EM-Fold.

Lindert S, Hofmann T, Wötzel N, Karakaş M, Stewart PL, Meiler J.

Biopolymers. 2012 Sep;97(9):669-77. doi: 10.1002/bip.22027. Epub 2012 Feb 3.

42.

Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy.

Henderson R, Chen S, Chen JZ, Grigorieff N, Passmore LA, Ciccarelli L, Rubinstein JL, Crowther RA, Stewart PL, Rosenthal PB.

J Mol Biol. 2011 Nov 11;413(5):1028-46. doi: 10.1016/j.jmb.2011.09.008. Epub 2011 Sep 12.

43.

Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA.

Pattanayek R, Williams DR, Rossi G, Weigand S, Mori T, Johnson CH, Stewart PL, Egli M.

PLoS One. 2011;6(8):e23697. doi: 10.1371/journal.pone.0023697. Epub 2011 Aug 24.

44.

BCL::EM-Fit: rigid body fitting of atomic structures into density maps using geometric hashing and real space refinement.

Woetzel N, Lindert S, Stewart PL, Meiler J.

J Struct Biol. 2011 Sep;175(3):264-76. doi: 10.1016/j.jsb.2011.04.016. Epub 2011 May 4.

45.

The cyanobacterial circadian system: from biophysics to bioevolution.

Johnson CH, Stewart PL, Egli M.

Annu Rev Biophys. 2011;40:143-67. doi: 10.1146/annurev-biophys-042910-155317. Review.

46.

Crystal structure of human adenovirus at 3.5 A resolution.

Reddy VS, Natchiar SK, Stewart PL, Nemerow GR.

Science. 2010 Aug 27;329(5995):1071-5. doi: 10.1126/science.1187292.

47.

HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach.

Matthews QL, Fatima A, Tang Y, Perry BA, Tsuruta Y, Komarova S, Timares L, Zhao C, Makarova N, Borovjagin AV, Stewart PL, Wu H, Blackwell JL, Curiel DT.

PLoS One. 2010 Jul 27;5(7):e11815. doi: 10.1371/journal.pone.0011815.

48.

Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization.

Smith JG, Silvestry M, Lindert S, Lu W, Nemerow GR, Stewart PL.

PLoS Pathog. 2010 Jun 24;6(6):e1000959. doi: 10.1371/journal.ppat.1000959.

49.

Crystallization and preliminary X-ray diffraction analysis of human adenovirus.

Reddy VS, Natchiar SK, Gritton L, Mullen TM, Stewart PL, Nemerow GR.

Virology. 2010 Jun 20;402(1):209-14. doi: 10.1016/j.virol.2010.03.028. Epub 2010 Apr 14.

50.

Adenovirus.

Smith JG, Wiethoff CM, Stewart PL, Nemerow GR.

Curr Top Microbiol Immunol. 2010;343:195-224. doi: 10.1007/82_2010_16. Review.

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