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Items: 1 to 50 of 294

1.

Modest enhancement of sensory axon regeneration in the sciatic nerve with conditional co-deletion of PTEN and SOCS3 in the dorsal root ganglia of adult mice.

Gallaher ZR, Steward O.

Exp Neurol. 2018 May;303:120-133. doi: 10.1016/j.expneurol.2018.02.012. Epub 2018 Feb 16.

2.

Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice.

Steward O, Matsudaira Yee K, Farris S, Pirbhoy PS, Worley P, Okamura K, Okuno H, Bito H.

Front Mol Neurosci. 2018 Jan 31;10:435. doi: 10.3389/fnmol.2017.00435. eCollection 2017.

3.

Electrophile-Dependent Alkylations of Lithiated 4-Alkoxyalk-4-enenitriles.

Pitta BR, Steward OW, Fleming FF.

J Org Chem. 2018 Mar 2;83(5):2753-2762. doi: 10.1021/acs.joc.7b03205. Epub 2018 Feb 16.

PMID:
29432696
4.

Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons.

Gallent EA, Steward O.

Exp Neurol. 2018 May;303:12-28. doi: 10.1016/j.expneurol.2018.01.005. Epub 2018 Jan 11.

5.

Electrophile-Directed Diastereoselective Oxonitrile Alkylations.

Chepyshev SV, Pitta BR, Vangala SR, Lujan-Montelongo JA, Steward OW, Fleming FF.

Chemistry. 2018 Feb 26;24(12):2850-2853. doi: 10.1002/chem.201705791. Epub 2018 Feb 5.

PMID:
29327787
6.
7.

Sulfone-Metal Exchange and Alkylation of Sulfonylnitriles.

Yang X, Nath D, Gau MR, Steward OW, Fleming FF.

Angew Chem Int Ed Engl. 2017 Jun 12;56(25):7257-7260. doi: 10.1002/anie.201704028. Epub 2017 May 19.

PMID:
28464420
8.

Recovery from Coma Post-Cardiac Arrest Is Dependent on the Orexin Pathway.

Kang YJ, Tian G, Bazrafkan A, Farahabadi MH, Azadian M, Abbasi H, Shamaoun BE, Steward O, Akbari Y.

J Neurotrauma. 2017 Oct 1;34(19):2823-2832. doi: 10.1089/neu.2016.4852. Epub 2017 Jun 16.

9.

Selective neuronal PTEN deletion: can we take the brakes off of growth without losing control?

Gutilla EA, Steward O.

Neural Regen Res. 2016 Aug;11(8):1201-3. doi: 10.4103/1673-5374.189160. Review.

10.

A Rhumba of "R's": Replication, Reproducibility, Rigor, Robustness: What Does a Failure to Replicate Mean?

Steward O.

eNeuro. 2016 Jul 7;3(4). pii: ENEURO.0072-16.2016. doi: 10.1523/ENEURO.0072-16.2016. eCollection 2016 Jul-Aug. No abstract available.

11.

Rodent spinal cord injury models for studies of axon regeneration.

Steward O, Willenberg R.

Exp Neurol. 2017 Jan;287(Pt 3):374-383. doi: 10.1016/j.expneurol.2016.06.029. Epub 2016 Jun 29. Review.

PMID:
27374113
12.

Synaptic activation of ribosomal protein S6 phosphorylation occurs locally in activated dendritic domains.

Pirbhoy PS, Farris S, Steward O.

Learn Mem. 2016 May 18;23(6):255-69. doi: 10.1101/lm.041947.116. Print 2016 Jun.

13.

Central Mechanisms Mediating Thrombospondin-4-induced Pain States.

Park J, Yu YP, Zhou CY, Li KW, Wang D, Chang E, Kim DS, Vo B, Zhang X, Gong N, Sharp K, Steward O, Vitko I, Perez-Reyes E, Eroglu C, Barres B, Zaucke F, Feng G, Luo ZD.

J Biol Chem. 2016 Jun 17;291(25):13335-48. doi: 10.1074/jbc.M116.723478. Epub 2016 Apr 19.

14.

Long-term consequences of conditional genetic deletion of PTEN in the sensorimotor cortex of neonatal mice.

Gutilla EA, Buyukozturk MM, Steward O.

Exp Neurol. 2016 May;279:27-39. doi: 10.1016/j.expneurol.2016.02.013. Epub 2016 Feb 16.

15.

Variable laterality of corticospinal tract axons that regenerate after spinal cord injury as a result of PTEN deletion or knock-down.

Willenberg R, Zukor K, Liu K, He Z, Steward O.

J Comp Neurol. 2016 Sep 1;524(13):2654-76. doi: 10.1002/cne.23987. Epub 2016 Mar 9.

16.

Sphingosine-1-phosphate receptor antagonism enhances proliferation and migration of engrafted neural progenitor cells in a model of viral-induced demyelination.

Blanc CA, Grist JJ, Rosen H, Sears-Kraxberger I, Steward O, Lane TE.

Am J Pathol. 2015 Oct;185(10):2819-32. doi: 10.1016/j.ajpath.2015.06.009.

17.

Robotic Rehabilitator of the Rodent Upper Extremity: A System and Method for Assessing and Training Forelimb Force Production after Neurological Injury.

Sharp KG, Duarte JE, Gebrekristos B, Perez S, Steward O, Reinkensmeyer DJ.

J Neurotrauma. 2016 Mar 1;33(5):460-7. doi: 10.1089/neu.2015.3987. Epub 2016 Jan 18.

18.

Synaptic ultrastructure changes in trigeminocervical complex posttrigeminal nerve injury.

Park J, Trinh VN, Sears-Kraxberger I, Li KW, Steward O, Luo ZD.

J Comp Neurol. 2016 Feb 1;524(2):309-22. doi: 10.1002/cne.23844. Epub 2015 Jul 16.

19.

Nonspecific labeling limits the utility of Cre-Lox bred CST-YFP mice for studies of corticospinal tract regeneration.

Willenberg R, Steward O.

J Comp Neurol. 2015 Dec 15;523(18):2665-82. doi: 10.1002/cne.23809. Epub 2015 Aug 10.

20.

Large animal and primate models of spinal cord injury for the testing of novel therapies.

Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, Fischer I, Floyd CL, Gensel JC, Houle JD, Jakeman LB, Jeffery ND, Jones LA, Kleitman N, Kocsis J, Lu P, Magnuson DS, Marsala M, Moore SW, Mothe AJ, Oudega M, Plant GW, Rabchevsky AS, Schwab JM, Silver J, Steward O, Xu XM, Guest JD, Tetzlaff W.

Exp Neurol. 2015 Jul;269:154-68. doi: 10.1016/j.expneurol.2015.04.008. Epub 2015 Apr 19.

PMID:
25902036
21.

Conditional genetic deletion of PTEN after a spinal cord injury enhances regenerative growth of CST axons and motor function recovery in mice.

Danilov CA, Steward O.

Exp Neurol. 2015 Apr;266:147-60. doi: 10.1016/j.expneurol.2015.02.012. Epub 2015 Feb 20.

22.

Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes.

Steward O, Farris S, Pirbhoy PS, Darnell J, Driesche SJ.

Front Mol Neurosci. 2015 Jan 12;7:101. doi: 10.3389/fnmol.2014.00101. eCollection 2014.

23.

Repair of spinal cord injury with neuronal relays: From fetal grafts to neural stem cells.

Bonner JF, Steward O.

Brain Res. 2015 Sep 4;1619:115-23. doi: 10.1016/j.brainres.2015.01.006. Epub 2015 Jan 12. Review.

24.

Leveraging biomedical informatics for assessing plasticity and repair in primate spinal cord injury.

Nielson JL, Haefeli J, Salegio EA, Liu AW, Guandique CF, Stück ED, Hawbecker S, Moseanko R, Strand SC, Zdunowski S, Brock JH, Roy RR, Rosenzweig ES, Nout-Lomas YS, Courtine G, Havton LA, Steward O, Reggie Edgerton V, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR.

Brain Res. 2015 Sep 4;1619:124-38. doi: 10.1016/j.brainres.2014.10.048. Epub 2014 Nov 4. Review.

25.

Rigor or mortis: best practices for preclinical research in neuroscience.

Steward O, Balice-Gordon R.

Neuron. 2014 Nov 5;84(3):572-81. doi: 10.1016/j.neuron.2014.10.042. Epub 2014 Nov 5. Review.

26.

Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.

Steward O, Sharp KG, Yee KM, Hatch MN, Bonner JF.

J Neurosci. 2014 Oct 15;34(42):14013-21. doi: 10.1523/JNEUROSCI.3066-14.2014.

27.

Development of a database for translational spinal cord injury research.

Nielson JL, Guandique CF, Liu AW, Burke DA, Lash AT, Moseanko R, Hawbecker S, Strand SC, Zdunowski S, Irvine KA, Brock JH, Nout-Lomas YS, Gensel JC, Anderson KD, Segal MR, Rosenzweig ES, Magnuson DS, Whittemore SR, McTigue DM, Popovich PG, Rabchevsky AG, Scheff SW, Steward O, Courtine G, Edgerton VR, Tuszynski MH, Beattie MS, Bresnahan JC, Ferguson AR.

J Neurotrauma. 2014 Nov 1;31(21):1789-99. doi: 10.1089/neu.2014.3399. Epub 2014 Jul 31.

29.

Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis.

Chen L, Coleman R, Leang R, Tran H, Kopf A, Walsh CM, Sears-Kraxberger I, Steward O, Macklin WB, Loring JF, Lane TE.

Stem Cell Reports. 2014 May 15;2(6):825-37. doi: 10.1016/j.stemcr.2014.04.005. eCollection 2014 Jun 3.

30.

Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy.

Smith ED, Prieto GA, Tong L, Sears-Kraxberger I, Rice JD, Steward O, Cotman CW.

J Biol Chem. 2014 Jul 25;289(30):20615-29.

31.

A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury.

Sharp KG, Yee KM, Steward O.

Exp Neurol. 2014 Jul;257:186-204. doi: 10.1016/j.expneurol.2014.04.008. Epub 2014 Apr 18.

32.

Selective localization of arc mRNA in dendrites involves activity- and translation-dependent mRNA degradation.

Farris S, Lewandowski G, Cox CD, Steward O.

J Neurosci. 2014 Mar 26;34(13):4481-93. doi: 10.1523/JNEUROSCI.4944-13.2014.

33.

Long-distance migration and colonization of transplanted neural stem cells.

Steward O, Sharp KG, Matsudaira Yee K.

Cell. 2014 Jan 30;156(3):385-7. doi: 10.1016/j.cell.2014.01.017. No abstract available.

34.

Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis.

Li KW, Yu YP, Zhou C, Kim DS, Lin B, Sharp K, Steward O, Luo ZD.

J Biol Chem. 2014 Mar 7;289(10):7025-37. doi: 10.1074/jbc.M114.548990. Epub 2014 Jan 23.

35.

A re-assessment of treatment with a tyrosine kinase inhibitor (imatinib) on tissue sparing and functional recovery after spinal cord injury.

Sharp KG, Yee KM, Steward O.

Exp Neurol. 2014 Apr;254:1-11. doi: 10.1016/j.expneurol.2013.12.019. Epub 2014 Jan 16.

PMID:
24440639
36.

A re-assessment of the effects of treatment with a non-steroidal anti-inflammatory (ibuprofen) on promoting axon regeneration via RhoA inhibition after spinal cord injury.

Sharp KG, Yee KM, Stiles TL, Aguilar RM, Steward O.

Exp Neurol. 2013 Oct;248:321-37. doi: 10.1016/j.expneurol.2013.06.023. Epub 2013 Jul 2.

PMID:
23830951
37.

Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception.

Zeng J, Kim D, Li KW, Sharp K, Steward O, Zaucke F, Luo ZD.

Eur J Pain. 2013 Nov;17(10):1458-64. doi: 10.1002/j.1532-2149.2013.00326.x. Epub 2013 May 7.

38.

Matrix metalloproteinase 3 deletion preserves denervated motor endplates after traumatic nerve injury.

Chao T, Frump D, Lin M, Caiozzo VJ, Mozaffar T, Steward O, Gupta R.

Ann Neurol. 2013 Feb;73(2):210-23. doi: 10.1002/ana.23781. Epub 2012 Dec 31.

PMID:
23281061
39.

A call for transparent reporting to optimize the predictive value of preclinical research.

Landis SC, Amara SG, Asadullah K, Austin CP, Blumenstein R, Bradley EW, Crystal RG, Darnell RB, Ferrante RJ, Fillit H, Finkelstein R, Fisher M, Gendelman HE, Golub RM, Goudreau JL, Gross RA, Gubitz AK, Hesterlee SE, Howells DW, Huguenard J, Kelner K, Koroshetz W, Krainc D, Lazic SE, Levine MS, Macleod MR, McCall JM, Moxley RT 3rd, Narasimhan K, Noble LJ, Perrin S, Porter JD, Steward O, Unger E, Utz U, Silberberg SD.

Nature. 2012 Oct 11;490(7419):187-91. doi: 10.1038/nature11556.

40.

Biophysical stimulation induces demyelination via an integrin-dependent mechanism.

Lin MY, Frieboes LS, Forootan M, Palispis WA, Mozaffar T, Jafari M, Steward O, Gall CM, Gupta R.

Ann Neurol. 2012 Jul;72(1):112-23. doi: 10.1002/ana.23592.

41.

Thrombospondin-4 contributes to spinal sensitization and neuropathic pain states.

Kim DS, Li KW, Boroujerdi A, Peter Yu Y, Zhou CY, Deng P, Park J, Zhang X, Lee J, Corpe M, Sharp K, Steward O, Eroglu C, Barres B, Zaucke F, Xu ZC, Luo ZD.

J Neurosci. 2012 Jun 27;32(26):8977-87. doi: 10.1523/JNEUROSCI.6494-11.2012.

42.

Concepts and methods for the study of axonal regeneration in the CNS.

Tuszynski MH, Steward O.

Neuron. 2012 Jun 7;74(5):777-91. doi: 10.1016/j.neuron.2012.05.006. Review.

43.

Chronic spinal cord injury impairs primary antibody responses but spares existing humoral immunity in mice.

Oropallo MA, Held KS, Goenka R, Ahmad SA, O'Neill PJ, Steward O, Lane TE, Cancro MP.

J Immunol. 2012 Jun 1;188(11):5257-66. doi: 10.4049/jimmunol.1101934. Epub 2012 Apr 20.

44.

Salmon fibrin treatment of spinal cord injury promotes functional recovery and density of serotonergic innervation.

Sharp KG, Dickson AR, Marchenko SA, Yee KM, Emery PN, Laidmåe I, Uibo R, Sawyer ES, Steward O, Flanagan LA.

Exp Neurol. 2012 May;235(1):345-56. doi: 10.1016/j.expneurol.2012.02.016. Epub 2012 Mar 5.

45.

A rat chronic pain model of spinal cord contusion injury.

Sharp K, Boroujerdi A, Steward O, Luo ZD.

Methods Mol Biol. 2012;851:195-203. doi: 10.1007/978-1-61779-561-9_14.

PMID:
22351092
47.

Age-Dependent Resistance to Excitotoxicity in Htt CAG140 Mice and the Effect of Strain Background.

Strong MK, Southwell AL, Yonan JM, Hayden MR, Macgregor GR, Thompson LM, Steward O.

J Huntingtons Dis. 2012;1(2):221-41. doi: 10.3233/JHD-129005.

48.
49.

Replication and reproducibility in spinal cord injury research.

Steward O, Popovich PG, Dietrich WD, Kleitman N.

Exp Neurol. 2012 Feb;233(2):597-605. doi: 10.1016/j.expneurol.2011.06.017. Epub 2011 Nov 10.

PMID:
22078756
50.

One day of motor training with amphetamine impairs motor recovery following spinal cord injury.

Wong JK, Steward O.

Exp Neurol. 2012 Feb;233(2):693-707. doi: 10.1016/j.expneurol.2011.08.011. Epub 2011 Nov 10.

PMID:
22078754

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