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Items: 46


Concordance for clonal hematopoiesis is limited in elderly twins.

Fabre MA, McKerrell T, Zwiebel M, Vijayabaskar MS, Park NR, Wells PM, Rad R, Deloukas P, Small KS, Steves CJ, Vassiliou GS.

Blood. 2019 Oct 25. pii: blood.2019001807. doi: 10.1182/blood.2019001807. [Epub ahead of print]


TwinsUK: The UK Adult Twin Registry Update.

Verdi S, Abbasian G, Bowyer RCE, Lachance G, Yarand D, Christofidou P, Mangino M, Menni C, Bell JT, Falchi M, Small KS, Williams FMK, Hammond CJ, Hart DJ, Spector TD, Steves CJ.

Twin Res Hum Genet. 2019 Sep 17:1-7. doi: 10.1017/thg.2019.65. [Epub ahead of print]


Dissecting the role of the gut microbiota and diet on visceral fat mass accumulation.

Le Roy CI, Bowyer RCE, Castillo-Fernandez JE, Pallister T, Menni C, Steves CJ, Berry SE, Spector TD, Bell JT.

Sci Rep. 2019 Jul 5;9(1):9758. doi: 10.1038/s41598-019-46193-w.


'RA and the microbiome: do host genetic factors provide the link?

Wells PM, Williams FMK, Matey-Hernandez ML, Menni C, Steves CJ.

J Autoimmun. 2019 May;99:104-115. doi: 10.1016/j.jaut.2019.02.004. Epub 2019 Mar 5. Review.


Epigenetic findings in periodontitis in UK twins: a cross-sectional study.

Kurushima Y, Tsai PC, Castillo-Fernandez J, Couto Alves A, El-Sayed Moustafa JS, Le Roy C, Spector TD, Ide M, Hughes FJ, Small KS, Steves CJ, Bell JT.

Clin Epigenetics. 2019 Feb 13;11(1):27. doi: 10.1186/s13148-019-0614-4.


Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study.

Bowyer RCE, Jackson MA, Le Roy CI, Ni Lochlainn M, Spector TD, Dowd JB, Steves CJ.

Microorganisms. 2019 Jan 11;7(1). pii: E17. doi: 10.3390/microorganisms7010017.


Response to: Population-Based Gut Microbiome Associations With Hypertension.

Steves CJ, Jackson MA.

Circ Res. 2018 Nov 9;123(11):1188-1189. doi: 10.1161/CIRCRESAHA.118.313913. No abstract available.


An Investigation Into Physical Frailty as a Link Between the Gut Microbiome and Cognitive Health.

Verdi S, Jackson MA, Beaumont M, Bowyer RCE, Bell JT, Spector TD, Steves CJ.

Front Aging Neurosci. 2018 Dec 4;10:398. doi: 10.3389/fnagi.2018.00398. eCollection 2018.


Genetic and environmental contributions to the association between mood disorder and periodontal disease: A cross-sectional study among female twins in the UK.

Kurushima Y, Bowyer R, Ide M, Hughes FJ, Steves CJ.

J Clin Periodontol. 2019 Jan;46(1):40-50. doi: 10.1111/jcpe.13045.


Multi-OMICS analyses of frailty and chronic widespread musculoskeletal pain suggest involvement of shared neurological pathways.

Livshits G, Malkin I, Bowyer RCE, Verdi S, Bell JT, Menni C, Williams FMK, Steves CJ.

Pain. 2018 Dec;159(12):2565-2572. doi: 10.1097/j.pain.0000000000001364.


Dietary Protein and Muscle in Aging People: The Potential Role of the Gut Microbiome.

Ni Lochlainn M, Bowyer RCE, Steves CJ.

Nutrients. 2018 Jul 20;10(7). pii: E929. doi: 10.3390/nu10070929. Review.


Gut microbiota associations with common diseases and prescription medications in a population-based cohort.

Jackson MA, Verdi S, Maxan ME, Shin CM, Zierer J, Bowyer RCE, Martin T, Williams FMK, Menni C, Bell JT, Spector TD, Steves CJ.

Nat Commun. 2018 Jul 9;9(1):2655. doi: 10.1038/s41467-018-05184-7.


The relationship between naevus count, memory function and telomere length in the Twins UK cohort.

Masi S, Georgiopoulos G, Ribero S, Taddei S, Bataille V, Steves CJ.

Pigment Cell Melanoma Res. 2018 Nov;31(6):720-724. doi: 10.1111/pcmr.12722. Epub 2018 Jul 19.


Meta-analysis of human genome-microbiome association studies: the MiBioGen consortium initiative.

Wang J, Kurilshikov A, Radjabzadeh D, Turpin W, Croitoru K, Bonder MJ, Jackson MA, Medina-Gomez C, Frost F, Homuth G, R├╝hlemann M, Hughes D, Kim HN; MiBioGen Consortium Initiative, Spector TD, Bell JT, Steves CJ, Timpson N, Franke A, Wijmenga C, Meyer K, Kacprowski T, Franke L, Paterson AD, Raes J, Kraaij R, Zhernakova A.

Microbiome. 2018 Jun 8;6(1):101. doi: 10.1186/s40168-018-0479-3.


The fecal metabolome as a functional readout of the gut microbiome.

Zierer J, Jackson MA, Kastenm├╝ller G, Mangino M, Long T, Telenti A, Mohney RP, Small KS, Bell JT, Steves CJ, Valdes AM, Spector TD, Menni C.

Nat Genet. 2018 Jun;50(6):790-795. doi: 10.1038/s41588-018-0135-7. Epub 2018 May 28.


Gut microbial diversity is associated with lower arterial stiffness in women.

Menni C, Lin C, Cecelja M, Mangino M, Matey-Hernandez ML, Keehn L, Mohney RP, Steves CJ, Spector TD, Kuo CF, Chowienczyk P, Valdes AM.

Eur Heart J. 2018 Jul 1;39(25):2390-2397. doi: 10.1093/eurheartj/ehy226.


Use of dietary indices to control for diet in human gut microbiota studies.

Bowyer RCE, Jackson MA, Pallister T, Skinner J, Spector TD, Welch AA, Steves CJ.

Microbiome. 2018 Apr 25;6(1):77. doi: 10.1186/s40168-018-0455-y.


Detection of stable community structures within gut microbiota co-occurrence networks from different human populations.

Jackson MA, Bonder MJ, Kuncheva Z, Zierer J, Fu J, Kurilshikov A, Wijmenga C, Zhernakova A, Bell JT, Spector TD, Steves CJ.

PeerJ. 2018 Feb 7;6:e4303. doi: 10.7717/peerj.4303. eCollection 2018.


Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome.

Pallister T, Jackson MA, Martin TC, Zierer J, Jennings A, Mohney RP, MacGregor A, Steves CJ, Cassidy A, Spector TD, Menni C.

Sci Rep. 2017 Oct 20;7(1):13670. doi: 10.1038/s41598-017-13722-4.


Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK.

Livshits G, Ni Lochlainn M, Malkin I, Bowyer R, Verdi S, Steves CJ, Williams FMK.

Age Ageing. 2018 Jan 1;47(1):119-125. doi: 10.1093/ageing/afx122.


Omega-3 fatty acids correlate with gut microbiome diversity and production of N-carbamylglutamate in middle aged and elderly women.

Menni C, Zierer J, Pallister T, Jackson MA, Long T, Mohney RP, Steves CJ, Spector TD, Valdes AM.

Sci Rep. 2017 Sep 11;7(1):11079. doi: 10.1038/s41598-017-10382-2.


Heritable components of the human fecal microbiome are associated with visceral fat.

Le Roy CI, Beaumont M, Jackson MA, Steves CJ, Spector TD, Bell JT.

Gut Microbes. 2018 Jan 2;9(1):61-67. doi: 10.1080/19490976.2017.1356556. Epub 2017 Aug 11.


Untangling the relationship between diet and visceral fat mass through blood metabolomics and gut microbiome profiling.

Pallister T, Jackson MA, Martin TC, Glastonbury CA, Jennings A, Beaumont M, Mohney RP, Small KS, MacGregor A, Steves CJ, Cassidy A, Spector TD, Menni C, Valdes AM.

Int J Obes (Lond). 2017 Jul;41(7):1106-1113. doi: 10.1038/ijo.2017.70. Epub 2017 Mar 15.


Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain.

Menni C, Jackson MA, Pallister T, Steves CJ, Spector TD, Valdes AM.

Int J Obes (Lond). 2017 Jul;41(7):1099-1105. doi: 10.1038/ijo.2017.66. Epub 2017 Mar 13.


Shotgun Metagenomics of 250 Adult Twins Reveals Genetic and Environmental Impacts on the Gut Microbiome.

Xie H, Guo R, Zhong H, Feng Q, Lan Z, Qin B, Ward KJ, Jackson MA, Xia Y, Chen X, Chen B, Xia H, Xu C, Li F, Xu X, Al-Aama JY, Yang H, Wang J, Kristiansen K, Wang J, Steves CJ, Bell JT, Li J, Spector TD, Jia H.

Cell Syst. 2016 Dec 21;3(6):572-584.e3. doi: 10.1016/j.cels.2016.10.004. Epub 2016 Nov 3.


The Identification of Hereditary and Environmental Determinants of Frailty in a Cohort of UK Twins.

Young AC, Glaser K, Spector TD, Steves CJ.

Twin Res Hum Genet. 2016 Dec;19(6):600-609. Epub 2016 Oct 10.


The correlation between cognitive performance and retinal nerve fibre layer thickness is largely explained by genetic factors.

Jones-Odeh E, Yonova-Doing E, Bloch E, Williams KM, Steves CJ, Hammond CJ.

Sci Rep. 2016 Sep 28;6:34116. doi: 10.1038/srep34116.


A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units.

Jackson MA, Bell JT, Spector TD, Steves CJ.

PeerJ. 2016 Aug 30;4:e2341. doi: 10.7717/peerj.2341. eCollection 2016.


Measurements of skeletal muscle mass and power are positively related to a Mediterranean dietary pattern in women.

Kelaiditi E, Jennings A, Steves CJ, Skinner J, Cassidy A, MacGregor AJ, Welch AA.

Osteoporos Int. 2016 Nov;27(11):3251-3260. doi: 10.1007/s00198-016-3665-9. Epub 2016 Jul 14.


Response to: The Microbiome: A Biological Mechanism Underpinning the Social Gradient of Musculoskeletal Conditions.

Steves CJ, Spector TD.

J Bone Miner Res. 2016 Jun;31(6):1316. doi: 10.1002/jbmr.2843. No abstract available.


Erratum to: signatures of early frailty in the gut microbiota.

Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Feb 17;8(1):21. doi: 10.1186/s13073-016-0275-2. No abstract available.


Signatures of early frailty in the gut microbiota.

Jackson MA, Jeffery IB, Beaumont M, Bell JT, Clark AG, Ley RE, O'Toole PW, Spector TD, Steves CJ.

Genome Med. 2016 Jan 29;8(1):8. doi: 10.1186/s13073-016-0262-7. Erratum in: Genome Med. 2016;8(1):21. Jackson, Matt [corrected to Jackson, Matthew A].


Aging Trajectories in Different Body Systems Share Common Environmental Etiology: The Healthy Aging Twin Study (HATS).

Moayyeri A, Hart DJ, Snieder H, Hammond CJ, Spector TD, Steves CJ.

Twin Res Hum Genet. 2016 Feb;19(1):27-34. doi: 10.1017/thg.2015.100.


Proton pump inhibitors alter the composition of the gut microbiota.

Jackson MA, Goodrich JK, Maxan ME, Freedberg DE, Abrams JA, Poole AC, Sutter JL, Welter D, Ley RE, Bell JT, Spector TD, Steves CJ.

Gut. 2016 May;65(5):749-56. doi: 10.1136/gutjnl-2015-310861. Epub 2015 Dec 30.


The Microbiome and Musculoskeletal Conditions of Aging: A Review of Evidence for Impact and Potential Therapeutics.

Steves CJ, Bird S, Williams FM, Spector TD.

J Bone Miner Res. 2016 Feb;31(2):261-9. doi: 10.1002/jbmr.2765. Review.


Kicking Back Cognitive Ageing: Leg Power Predicts Cognitive Ageing after Ten Years in Older Female Twins.

Steves CJ, Mehta MM, Jackson SH, Spector TD.

Gerontology. 2016;62(2):138-49. doi: 10.1159/000441029. Epub 2015 Nov 10.


Dietary Magnesium Is Positively Associated With Skeletal Muscle Power and Indices of Muscle Mass and May Attenuate the Association Between Circulating C-Reactive Protein and Muscle Mass in Women.

Welch AA, Kelaiditi E, Jennings A, Steves CJ, Spector TD, MacGregor A.

J Bone Miner Res. 2016 Feb;31(2):317-25. doi: 10.1002/jbmr.2692. Epub 2015 Sep 11.


Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.

Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ.

Transl Psychiatry. 2015 Jun 16;5:e584. doi: 10.1038/tp.2015.78.


Genomics and metabolomics of muscular mass in a community-based sample of UK females.

Korostishevsky M, Steves CJ, Malkin I, Spector T, Williams FM, Livshits G.

Eur J Hum Genet. 2016 Feb;24(2):277-83. doi: 10.1038/ejhg.2015.85. Epub 2015 Apr 22.


Epigenome-wide DNA methylation in hearing ability: new mechanisms for an old problem.

Wolber LE, Steves CJ, Tsai PC, Deloukas P, Spector TD, Bell JT, Williams FM.

PLoS One. 2014 Sep 3;9(9):e105729. doi: 10.1371/journal.pone.0105729. eCollection 2014.


Cognitive change in older women using a computerised battery: a longitudinal quantitative genetic twin study.

Steves CJ, Jackson SH, Spector TD.

Behav Genet. 2013 Nov;43(6):468-79. doi: 10.1007/s10519-013-9612-z. Epub 2013 Aug 30.


Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect.

Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, de Geus EJ, Henders A, Nelson CP, Steves CJ, Wright MJ, de Craen AJ, Isaacs A, Matthews M, Moayyeri A, Montgomery GW, Oostra BA, Vink JM, Spector TD, Slagboom PE, Martin NG, Samani NJ, van Duijn CM, Boomsma DI.

Eur J Hum Genet. 2013 Oct;21(10):1163-8. doi: 10.1038/ejhg.2012.303. Epub 2013 Jan 16.


Ageing, genes, environment and epigenetics: what twin studies tell us now, and in the future.

Steves CJ, Spector TD, Jackson SH.

Age Ageing. 2012 Sep;41(5):581-6. doi: 10.1093/ageing/afs097. Epub 2012 Jul 23. Review.


Hearing ability with age in northern European women: a new web-based approach to genetic studies.

Wolber LE, Steves CJ, Spector TD, Williams FM.

PLoS One. 2012;7(4):e35500. doi: 10.1371/journal.pone.0035500. Epub 2012 Apr 30.


Management of tuberculosis in a British inner-city population.

White VL, Paliwalla M, Steves CJ, Jadhav D, Moore-Gillon J.

J Public Health Med. 2002 Mar;24(1):49-52.


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