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Items: 1 to 50 of 91

1.

Pharmacologic targeting of the ATX/LPA axis attenuates bleomycin-induced pulmonary fibrosis.

Ninou I, Kaffe E, Müller S, Budd DC, Stevenson CS, Ullmer C, Aidinis V.

Pulm Pharmacol Ther. 2018 Oct;52:32-40. doi: 10.1016/j.pupt.2018.08.003. Epub 2018 Sep 7.

PMID:
30201409
2.

The glass transition temperature of thin films: A molecular dynamics study for a bead-spring model.

Stevenson CS, Curro JG, McCoy JD.

J Chem Phys. 2017 May 28;146(20):203322. doi: 10.1063/1.4977521.

PMID:
28571355
3.

Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue.

Vasilescu DM, Phillion AB, Tanabe N, Kinose D, Paige DF, Kantrowitz JJ, Liu G, Liu H, Fishbane N, Verleden SE, Vanaudenaerde BM, Lenburg M, Stevenson CS, Spira A, Cooper JD, Hackett TL, Hogg JC.

J Appl Physiol (1985). 2017 Jan 1;122(1):161-169. doi: 10.1152/japplphysiol.00838.2016. Epub 2016 Nov 17.

4.

Persistence of circulating endothelial microparticles in COPD despite smoking cessation.

Strulovici-Barel Y, Staudt MR, Krause A, Gordon C, Tilley AE, Harvey BG, Kaner RJ, Hollmann C, Mezey JG, Bitter H, Pillai SG, Hilton H, Wolff G, Stevenson CS, Visvanathan S, Fine JS, Crystal RG.

Thorax. 2016 Dec;71(12):1137-1144. doi: 10.1136/thoraxjnl-2015-208274. Epub 2016 Jul 26.

5.

Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of Asthma.

Phillips JE, Renteria L, Burns L, Harris P, Peng R, Bauer CM, Laine D, Stevenson CS.

J Aerosol Med Pulm Drug Deliv. 2016 Jun;29(3):233-41. doi: 10.1089/jamp.2015.1210. Epub 2016 Apr 25.

6.

Cigarette Smoke Attenuates the Nasal Host Response to Streptococcus pneumoniae and Predisposes to Invasive Pneumococcal Disease in Mice.

Shen P, Morissette MC, Vanderstocken G, Gao Y, Hassan M, Roos A, Thayaparan D, Merlano M, Dorrington MG, Nikota JK, Bauer CMT, Kwiecien JM, Labiris R, Bowdish DME, Stevenson CS, Stämpfli MR.

Infect Immun. 2016 Apr 22;84(5):1536-1547. doi: 10.1128/IAI.01504-15. Print 2016 May.

7.

IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Roos AB, Sethi S, Nikota J, Wrona CT, Dorrington MG, Sandén C, Bauer CM, Shen P, Bowdish D, Stevenson CS, Erjefält JS, Stampfli MR.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):428-37. doi: 10.1164/rccm.201409-1689OC.

PMID:
26039632
8.

Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

Wang G, Wang R, Strulovici-Barel Y, Salit J, Staudt MR, Ahmed J, Tilley AE, Yee-Levin J, Hollmann C, Harvey BG, Kaner RJ, Mezey JG, Sridhar S, Pillai SG, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine JS, Stevenson CS, Crystal RG.

PLoS One. 2015 Apr 17;10(4):e0120824. doi: 10.1371/journal.pone.0120824. eCollection 2015.

9.

Role of the inflammasome-caspase1/11-IL-1/18 axis in cigarette smoke driven airway inflammation: an insight into the pathogenesis of COPD.

Eltom S, Belvisi MG, Stevenson CS, Maher SA, Dubuis E, Fitzgerald KA, Birrell MA.

PLoS One. 2014 Nov 18;9(11):e112829. doi: 10.1371/journal.pone.0112829. eCollection 2014.

10.

Discovery of novel non-carboxylic acid 5-amino-4-cyanopyrazole derivatives as potent and highly selective LPA1R antagonists.

Sidduri A, Budd DC, Fuentes ME, Lambros T, Ren Y, Roongta V, Schoenfeld RC, Gillespie P, Stevenson CS, Truitt T, Qian Y.

Bioorg Med Chem Lett. 2014 Sep 15;24(18):4450-4454. doi: 10.1016/j.bmcl.2014.08.001. Epub 2014 Aug 8.

PMID:
25155385
11.

Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD.

Eltom S, Dale N, Raemdonck KR, Stevenson CS, Snelgrove RJ, Sacitharan PK, Recchi C, Wavre-Shapton S, McAuley DF, O'Kane C, Belvisi MG, Birrell MA.

PLoS One. 2014 Jun 27;9(6):e101087. doi: 10.1371/journal.pone.0101087. eCollection 2014.

12.

Intraflagellar transport gene expression associated with short cilia in smoking and COPD.

Hessel J, Heldrich J, Fuller J, Staudt MR, Radisch S, Hollmann C, Harvey BG, Kaner RJ, Salit J, Yee-Levin J, Sridhar S, Pillai S, Hilton H, Wolff G, Bitter H, Visvanathan S, Fine J, Stevenson CS, Crystal RG, Tilley AE.

PLoS One. 2014 Jan 20;9(1):e85453. doi: 10.1371/journal.pone.0085453. eCollection 2014.

13.

Antigen-induced mast cell expansion and bronchoconstriction in a mouse model of asthma.

Li S, Aliyeva M, Daphtary N, Martin RA, Poynter ME, Kostin SF, van der Velden JL, Hyman AM, Stevenson CS, Phillips JE, Lundblad LK.

Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L196-206. doi: 10.1152/ajplung.00055.2013. Epub 2013 Nov 27.

14.

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression.

Buro-Auriemma LJ, Salit J, Hackett NR, Walters MS, Strulovici-Barel Y, Staudt MR, Fuller J, Mahmoud M, Stevenson CS, Hilton H, Ho MW, Crystal RG.

Hum Mol Genet. 2013 Dec 1;22(23):4726-38. doi: 10.1093/hmg/ddt326. Epub 2013 Jul 10.

15.

Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.

Tang X, Peng R, Phillips JE, Deguzman J, Ren Y, Apparsundaram S, Luo Q, Bauer CM, Fuentes ME, DeMartino JA, Tyagi G, Garrido R, Hogaboam CM, Denton CP, Holmes AM, Kitson C, Stevenson CS, Budd DC.

Am J Pathol. 2013 Aug;183(2):470-9. doi: 10.1016/j.ajpath.2013.04.020. Epub 2013 Jun 10.

PMID:
23759512
16.

Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease.

Peng R, Sridhar S, Tyagi G, Phillips JE, Garrido R, Harris P, Burns L, Renteria L, Woods J, Chen L, Allard J, Ravindran P, Bitter H, Liang Z, Hogaboam CM, Kitson C, Budd DC, Fine JS, Bauer CM, Stevenson CS.

PLoS One. 2013;8(4):e59348. doi: 10.1371/journal.pone.0059348. Epub 2013 Apr 2.

17.

Predicting drug efficacy using integrative models for chronic respiratory diseases.

Stevenson CS, Sridhar S, Phillips JE.

Inflamm Allergy Drug Targets. 2013 Apr;12(2):124-31. Review.

PMID:
23517645
18.

House dust mite models: will they translate clinically as a superior model of asthma?

Phillips JE, Peng R, Harris P, Burns L, Renteria L, Lundblad LK, Fine JS, Bauer CM, Stevenson CS.

J Allergy Clin Immunol. 2013 Jul;132(1):242-4. doi: 10.1016/j.jaci.2012.12.1571. Epub 2013 Feb 10. No abstract available.

PMID:
23403050
19.

Is intrinsic aerobic exercise capacity a determinant of COPD susceptibility?

Stevenson CS, Yew-Booth L.

Pulm Pharmacol Ther. 2013 Aug;26(4):459-63. doi: 10.1016/j.pupt.2013.01.004. Epub 2013 Jan 23.

PMID:
23353136
20.

Cigarette smoke induced airway inflammation is independent of NF-κB signalling.

Rastrick JM, Stevenson CS, Eltom S, Grace M, Davies M, Kilty I, Evans SM, Pasparakis M, Catley MC, Lawrence T, Adcock IM, Belvisi MG, Birrell MA.

PLoS One. 2013;8(1):e54128. doi: 10.1371/journal.pone.0054128. Epub 2013 Jan 22. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/754d7b19-2dac-479b-a23c-db9fed0431be.

21.

BET bromodomain proteins mediate downstream signaling events following growth factor stimulation in human lung fibroblasts and are involved in bleomycin-induced pulmonary fibrosis.

Tang X, Peng R, Ren Y, Apparsundaram S, Deguzman J, Bauer CM, Hoffman AF, Hamilton S, Liang Z, Zeng H, Fuentes ME, Demartino JA, Kitson C, Stevenson CS, Budd DC.

Mol Pharmacol. 2013 Jan;83(1):283-93. doi: 10.1124/mol.112.081661. Epub 2012 Oct 31.

PMID:
23115324
22.

Double-stranded RNA induces molecular and inflammatory signatures that are directly relevant to COPD.

Harris P, Sridhar S, Peng R, Phillips JE, Cohn RG, Burns L, Woods J, Ramanujam M, Loubeau M, Tyagi G, Allard J, Burczynski M, Ravindran P, Cheng D, Bitter H, Fine JS, Bauer CM, Stevenson CS.

Mucosal Immunol. 2013 May;6(3):474-84. doi: 10.1038/mi.2012.86. Epub 2012 Sep 19.

23.

Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts.

Qian Y, Hamilton M, Sidduri A, Gabriel S, Ren Y, Peng R, Kondru R, Narayanan A, Truitt T, Hamid R, Chen Y, Zhang L, Fretland AJ, Sanchez RA, Chang KC, Lucas M, Schoenfeld RC, Laine D, Fuentes ME, Stevenson CS, Budd DC.

J Med Chem. 2012 Sep 13;55(17):7920-39. doi: 10.1021/jm301022v. Epub 2012 Aug 29.

PMID:
22894757
24.

Bleomycin induced lung fibrosis increases work of breathing in the mouse.

Phillips JE, Peng R, Burns L, Harris P, Garrido R, Tyagi G, Fine JS, Stevenson CS.

Pulm Pharmacol Ther. 2012 Aug;25(4):281-5. doi: 10.1016/j.pupt.2011.10.001. Epub 2011 Oct 20.

PMID:
22024054
25.

P2X7 receptor and caspase 1 activation are central to airway inflammation observed after exposure to tobacco smoke.

Eltom S, Stevenson CS, Rastrick J, Dale N, Raemdonck K, Wong S, Catley MC, Belvisi MG, Birrell MA.

PLoS One. 2011;6(9):e24097. doi: 10.1371/journal.pone.0024097. Epub 2011 Sep 6.

26.

Moving towards a new generation of animal models for asthma and COPD with improved clinical relevance.

Stevenson CS, Birrell MA.

Pharmacol Ther. 2011 May;130(2):93-105. doi: 10.1016/j.pharmthera.2010.10.008. Epub 2010 Nov 11. Review.

PMID:
21074553
27.

Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation.

Wan WY, Morris A, Kinnear G, Pearce W, Mok J, Wyss D, Stevenson CS.

Respir Res. 2010 Sep 18;11:126. doi: 10.1186/1465-9921-11-126.

28.

Cigarette Smoke Exposure Alters mSin3a and Mi-2alpha/beta Expression; implications in the control of pro-inflammatory gene transcription and glucocorticoid function.

Marwick JA, Stevenson CS, Chung KF, Adcock IM, Kirkham PA.

J Inflamm (Lond). 2010 Jul 16;7:33. doi: 10.1186/1476-9255-7-33.

29.

Cigarette smoke regulates VEGFR2-mediated survival signaling in rat lungs.

Marwick JA, Edirisinghe I, Arunachalam G, Stevenson CS, Macnee W, Kirkham PA, Rahman I.

J Inflamm (Lond). 2010 Feb 13;7(1):11. doi: 10.1186/1476-9255-7-11.

30.

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.

Marwick JA, Caramori G, Stevenson CS, Casolari P, Jazrawi E, Barnes PJ, Ito K, Adcock IM, Kirkham PA, Papi A.

Am J Respir Crit Care Med. 2009 Apr 1;179(7):542-8. doi: 10.1164/rccm.200810-1570OC. Epub 2009 Jan 22.

31.

Preclinical animal models of asthma and chronic obstructive pulmonary disease.

Stevenson CS, Belvisi MG.

Expert Rev Respir Med. 2008 Oct;2(5):631-43. doi: 10.1586/17476348.2.5.631.

PMID:
20477298
32.

Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses.

Morris A, Kinnear G, Wan WY, Wyss D, Bahra P, Stevenson CS.

J Pharmacol Exp Ther. 2008 Dec;327(3):851-62. doi: 10.1124/jpet.108.140848. Epub 2008 Sep 19.

PMID:
18806126
33.

Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.

Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K.

Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1183-93. Epub 2007 Aug 24.

34.

Borderline personality disorder, mother-infant interaction and parenting perceptions: preliminary findings.

Newman LK, Stevenson CS, Bergman LR, Boyce P.

Aust N Z J Psychiatry. 2007 Jul;41(7):598-605.

PMID:
17558622
35.

Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition.

Marwick JA, Stevenson CS, Giddings J, MacNee W, Butler K, Rahman I, Kirkham PA.

Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L897-908. Epub 2005 Dec 16.

36.

Aerobic capacity, oxidant stress, and chronic obstructive pulmonary disease--a new take on an old hypothesis.

Stevenson CS, Koch LG, Britton SL.

Pharmacol Ther. 2006 Apr;110(1):71-82. Epub 2005 Dec 15. Review.

PMID:
16343638
37.

Effect of adenosine A2A receptor activation in murine models of respiratory disorders.

Bonneau O, Wyss D, Ferretti S, Blaydon C, Stevenson CS, Trifilieff A.

Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L1036-43. Epub 2005 Dec 9.

38.

Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect.

Stevenson CS, Coote K, Webster R, Johnston H, Atherton HC, Nicholls A, Giddings J, Sugar R, Jackson A, Press NJ, Brown Z, Butler K, Danahay H.

Am J Physiol Lung Cell Mol Physiol. 2005 Mar;288(3):L514-22. Epub 2004 Oct 29.

39.

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.

Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I.

Am J Respir Cell Mol Biol. 2004 Dec;31(6):633-42. Epub 2004 Aug 27.

PMID:
15333327
40.

The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore.

Stevenson CS, Capper EA, Roshak AK, Marquez B, Eichman C, Jackson JR, Mattern M, Gerwick WH, Jacobs RS, Marshall LA.

J Pharmacol Exp Ther. 2002 Nov;303(2):858-66.

PMID:
12388673
41.

Rapid hydrolytic cleavage of the mRNA model compound HPNP by glycine based macrocyclic lanthanide ribonuclease mimics.

Gunnlaugsson T, Davies RJ, Nieuwenhuyzen M, Stevenson CS, Viguier R, Mulready S.

Chem Commun (Camb). 2002 Sep 21;(18):2136-7.

PMID:
12357812
42.

A cognitive remediation programme for adults with Attention Deficit Hyperactivity Disorder.

Stevenson CS, Whitmont S, Bornholt L, Livesey D, Stevenson RJ.

Aust N Z J Psychiatry. 2002 Oct;36(5):610-6.

PMID:
12225443
43.

Scytonemin--a marine natural product inhibitor of kinases key in hyperproliferative inflammatory diseases.

Stevenson CS, Capper EA, Roshak AK, Marquez B, Grace K, Gerwick WH, Jacobs RS, Marshall LA.

Inflamm Res. 2002 Feb;51(2):112-4. No abstract available.

PMID:
11926312
44.

Homo- and nor-plakotenin, new carboxylic acids from the Palauan sponge Plakortis lita.

Qureshi A, Stevenson CS, Albert CL, Jacobs RS, Faulkner DJ.

J Nat Prod. 1999 Aug;62(8):1205-7.

PMID:
10479343
45.

Protecting children from abuse and neglect: analysis and recommendations.

Larner MB, Stevenson CS, Behrman RE.

Future Child. 1998 Spring;8(1):4-22. Review. No abstract available.

PMID:
9675997
46.

The juvenile court: analysis and recommendations.

Stevenson CS, Larson CS, Carter LS, Gomby DS, Terman DL, Behrman RE.

Future Child. 1996 Winter;6(3):4-28. Review. No abstract available.

PMID:
9117364
47.

Financing child care: analysis and recommendations.

Gomby DS, Krantzler N, Larner MB, Stevenson CS, Terman DL, Behrman RE.

Future Child. 1996 Summer-Fall;6(2):5-25. Review. No abstract available.

PMID:
8972125
48.

Special education for students with disabilities: analysis and recommendations.

Terman DL, Larner MB, Stevenson CS, Behrman RE.

Future Child. 1996 Spring;6(1):4-24. Review.

PMID:
8689260
49.

Long-term outcomes of early childhood programs: analysis and recommendations.

Gomby DS, Larner MB, Stevenson CS, Lewit EM, Behrman RE.

Future Child. 1995 Winter;5(3):6-24. Review. No abstract available.

PMID:
8835513
50.

Gaps and excesses in the regulation of child day care: report of a panel.

Morgan GG, Stevenson CS, Fiene R, Stephens KO.

Rev Infect Dis. 1986 Jul-Aug;8(4):634-43.

PMID:
3749689

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