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1.

DNA methylation age is accelerated in alcohol dependence.

Rosen AD, Robertson KD, Hlady RA, Muench C, Lee J, Philibert R, Horvath S, Kaminsky ZA, Lohoff FW.

Transl Psychiatry. 2018 Sep 5;8(1):182. doi: 10.1038/s41398-018-0233-4.

2.

Increased epigenetic age in normal breast tissue from luminal breast cancer patients.

Hofstatter EW, Horvath S, Dalela D, Gupta P, Chagpar AB, Wali VB, Bossuyt V, Storniolo AM, Hatzis C, Patwardhan G, Von Wahlde MK, Butler M, Epstein L, Stavris K, Sturrock T, Au A, Kwei S, Pusztai L.

Clin Epigenetics. 2018 Aug 29;10(1):112. doi: 10.1186/s13148-018-0534-8.

3.

Intraindividual variability in neurocognitive performance: No influence due to HIV status or self-reported effort.

Levine AJ, Martin E, Munro CA, Sacktor N, Horvath S, Becker JT; Multicenter AIDS Cohort Study–Neuropsychology Working Group.

J Clin Exp Neuropsychol. 2018 Dec;40(10):1044-1049. doi: 10.1080/13803395.2018.1508554. Epub 2018 Aug 20.

PMID:
30124355
4.

Breast cancer treatment and its effects on aging.

Chang L, Weiner LS, Hartman SJ, Horvath S, Jeste D, Mischel PS, Kado DM.

J Geriatr Oncol. 2018 Aug 2. pii: S1879-4068(18)30117-6. doi: 10.1016/j.jgo.2018.07.010. [Epub ahead of print] Review.

PMID:
30078714
5.

Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies.

Horvath S, Oshima J, Martin GM, Lu AT, Quach A, Cohen H, Felton S, Matsuyama M, Lowe D, Kabacik S, Wilson JG, Reiner AP, Maierhofer A, Flunkert J, Aviv A, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Ferrucci L, Matsuyama S, Raj K.

Aging (Albany NY). 2018 Jul 26;10(7):1758-1775. doi: 10.18632/aging.101508.

6.

Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism.

Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH.

Nature. 2018 Aug;560(7718):E30. doi: 10.1038/s41586-018-0295-8.

PMID:
29995847
7.

Genetic and epigenetic changes in clonal descendants of irradiated human fibroblasts.

Flunkert J, Maierhofer A, Dittrich M, Müller T, Horvath S, Nanda I, Haaf T.

Exp Cell Res. 2018 Sep 15;370(2):322-332. doi: 10.1016/j.yexcr.2018.06.034. Epub 2018 Jun 28.

8.

Perinatally acquired HIV infection accelerates epigenetic aging in South African adolescents.

Horvath S, Stein DJ, Phillips N, Heany SJ, Kobor MS, Lin DTS, Myer L, Zar HJ, Levine AJ, Hoare J.

AIDS. 2018 Jul 17;32(11):1465-1474. doi: 10.1097/QAD.0000000000001854.

PMID:
29746298
9.

Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.

Marioni RE, Suderman M, Chen BH, Horvath S, Bandinelli S, Morris T, Beck S, Ferrucci L, Pedersen NL, Relton CL, Deary IJ, Hägg S.

J Gerontol A Biol Sci Med Sci. 2018 Mar 20. doi: 10.1093/gerona/gly060. [Epub ahead of print]

PMID:
29718110
10.

Metabolic and inflammatory biomarkers are associated with epigenetic aging acceleration estimates in the GOLDN study.

Irvin MR, Aslibekyan S, Do A, Zhi D, Hidalgo B, Claas SA, Srinivasasainagendra V, Horvath S, Tiwari HK, Absher DM, Arnett DK.

Clin Epigenetics. 2018 Apr 18;10:56. doi: 10.1186/s13148-018-0481-4. eCollection 2018.

11.

An epigenetic biomarker of aging for lifespan and healthspan.

Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S.

Aging (Albany NY). 2018 Apr 18;10(4):573-591. doi: 10.18632/aging.101414.

12.

DNA methylation-based biomarkers and the epigenetic clock theory of ageing.

Horvath S, Raj K.

Nat Rev Genet. 2018 Jun;19(6):371-384. doi: 10.1038/s41576-018-0004-3. Review.

PMID:
29643443
13.

No reliable gene expression biomarkers of current or impending neurocognitive impairment in peripheral blood monocytes of persons living with HIV.

Quach A, Horvath S, Nemanim N, Vatakis D, Witt MD, Miller EN, Detels R, Langfelder P, Shapshak P, Singer EJ, Levine AJ.

J Neurovirol. 2018 Jun;24(3):350-361. doi: 10.1007/s13365-018-0625-5. Epub 2018 Mar 26.

14.

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.

Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP; CommonMind Consortium; PsychENCODE Consortium; iPSYCH-BROAD Working Group, Horvath S, Geschwind DH.

Science. 2018 Feb 9;359(6376):693-697. doi: 10.1126/science.aad6469.

15.

GWAS of epigenetic aging rates in blood reveals a critical role for TERT.

Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S.

Nat Commun. 2018 Jan 26;9(1):387. doi: 10.1038/s41467-017-02697-5.

16.

MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.

Langfelder P, Gao F, Wang N, Howland D, Kwak S, Vogt TF, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW.

PLoS One. 2018 Jan 11;13(1):e0190550. doi: 10.1371/journal.pone.0190550. eCollection 2018.

17.

Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls.

Binder AM, Corvalan C, Mericq V, Pereira A, Santos JL, Horvath S, Shepherd J, Michels KB.

Epigenetics. 2018;13(1):85-94. doi: 10.1080/15592294.2017.1414127. Epub 2018 Feb 15.

PMID:
29235933
18.

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.

Richard MA, Huan T, Ligthart S, Gondalia R, Jhun MA, Brody JA, Irvin MR, Marioni R, Shen J, Tsai PC, Montasser ME, Jia Y, Syme C, Salfati EL, Boerwinkle E, Guan W, Mosley TH Jr, Bressler J, Morrison AC, Liu C, Mendelson MM, Uitterlinden AG, van Meurs JB; BIOS Consortium, Franco OH, Zhang G, Li Y, Stewart JD, Bis JC, Psaty BM, Chen YI, Kardia SLR, Zhao W, Turner ST, Absher D, Aslibekyan S, Starr JM, McRae AF, Hou L, Just AC, Schwartz JD, Vokonas PS, Menni C, Spector TD, Shuldiner A, Damcott CM, Rotter JI, Palmas W, Liu Y, Paus T, Horvath S, O'Connell JR, Guo X, Pausova Z, Assimes TL, Sotoodehnia N, Smith JA, Arnett DK, Deary IJ, Baccarelli AA, Bell JT, Whitsel E, Dehghan A, Levy D, Fornage M.

Am J Hum Genet. 2017 Dec 7;101(6):888-902. doi: 10.1016/j.ajhg.2017.09.028. Epub 2017 Nov 30.

19.

Neuropathological and transcriptomic characteristics of the aged brain.

Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N, Desta T, Dolbeare TA, Dotson NI, Fisher M, Gaudreault N, Gee G, Gilbert TL, Goldy J, Griffin F, Habel C, Haradon Z, Hejazinia N, Hellstern LL, Horvath S, Howard K, Howard R, Johal J, Jorstad NL, Josephsen SR, Kuan CL, Lai F, Lee E, Lee F, Lemon T, Li X, Marshall DA, Melchor J, Mukherjee S, Nyhus J, Pendergraft J, Potekhina L, Rha EY, Rice S, Rosen D, Sapru A, Schantz A, Shen E, Sherfield E, Shi S, Sodt AJ, Thatra N, Tieu M, Wilson AM, Montine TJ, Larson EB, Bernard A, Crane PK, Ellenbogen RG, Keene CD, Lein E.

Elife. 2017 Nov 9;6. pii: e31126. doi: 10.7554/eLife.31126.

20.

Leukocyte telomere length, T cell composition and DNA methylation age.

Chen BH, Carty CL, Kimura M, Kark JD, Chen W, Li S, Zhang T, Kooperberg C, Levy D, Assimes T, Absher D, Horvath S, Reiner AP, Aviv A.

Aging (Albany NY). 2017 Sep 20;9(9):1983-1995. doi: 10.18632/aging.101293.

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