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Items: 1 to 50 of 71

1.

Tight nuclear tethering of cGAS is essential for preventing autoreactivity.

Volkman HE, Cambier S, Gray EE, Stetson DB.

Elife. 2019 Dec 6;8. pii: e47491. doi: 10.7554/eLife.47491. [Epub ahead of print]

PMID:
31808743
2.

Exon 16-Skipping HER2 as a Novel Mechanism of Osimertinib Resistance in EGFR L858R/T790M-Positive Non-Small Cell Lung Cancer.

Hsu CC, Liao BC, Liao WY, Markovets A, Stetson D, Thress K, Chih-Hsin Yang J.

J Thorac Oncol. 2019 Sep 23. pii: S1556-0864(19)33307-6. doi: 10.1016/j.jtho.2019.09.006. [Epub ahead of print]

PMID:
31557536
3.

An assessment of vegetation management practices and burrow fumigation with aluminum phosphide as tools for managing voles within perennial crop fields in California, USA.

Baldwin RA, Stetson DI, Lopez MG, Engeman RM.

Environ Sci Pollut Res Int. 2019 Jun;26(18):18434-18439. doi: 10.1007/s11356-019-05235-6. Epub 2019 May 2.

PMID:
31049861
4.

Editorial overview: Autoimmunity: A new frontier awaits.

Stetson DB.

Curr Opin Immunol. 2018 Dec;55:iii-iv. doi: 10.1016/j.coi.2018.11.005. No abstract available.

5.

SUMO2 and SUMO3 redundantly prevent a noncanonical type I interferon response.

Crowl JT, Stetson DB.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6798-6803. doi: 10.1073/pnas.1802114115. Epub 2018 Jun 11.

6.

Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling.

Brault M, Olsen TM, Martinez J, Stetson DB, Oberst A.

J Immunol. 2018 Apr 15;200(8):2748-2756. doi: 10.4049/jimmunol.1701492. Epub 2018 Mar 14.

7.

Generation of stable PDX derived cell lines using conditional reprogramming.

Borodovsky A, McQuiston TJ, Stetson D, Ahmed A, Whitston D, Zhang J, Grondine M, Lawson D, Challberg SS, Zinda M, Pollok BA, Dougherty BA, D'Cruz CM.

Mol Cancer. 2017 Dec 6;16(1):177. doi: 10.1186/s12943-017-0745-1.

8.

Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer.

Ramalingam SS, Yang JC, Lee CK, Kurata T, Kim DW, John T, Nogami N, Ohe Y, Mann H, Rukazenkov Y, Ghiorghiu S, Stetson D, Markovets A, Barrett JC, Thress KS, Jänne PA.

J Clin Oncol. 2018 Mar 20;36(9):841-849. doi: 10.1200/JCO.2017.74.7576. Epub 2017 Aug 25.

PMID:
28841389
9.

The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.

Gorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ.

Nat Immunol. 2017 Jul;18(7):744-752. doi: 10.1038/ni.3766. Epub 2017 May 29.

10.

Prioritisation of structural variant calls in cancer genomes.

Ahdesmäki MJ, Chapman BA, Cingolani P, Hofmann O, Sidoruk A, Lai Z, Zakharov G, Rodichenko M, Alperovich M, Jenkins D, Carr TH, Stetson D, Dougherty B, Barrett JC, Johnson JH.

PeerJ. 2017 Apr 4;5:e3166. doi: 10.7717/peerj.3166. eCollection 2017.

11.

Intracellular Nucleic Acid Detection in Autoimmunity.

Crowl JT, Gray EE, Pestal K, Volkman HE, Stetson DB.

Annu Rev Immunol. 2017 Apr 26;35:313-336. doi: 10.1146/annurev-immunol-051116-052331. Epub 2017 Jan 30. Review.

12.

The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.

Gray EE, Winship D, Snyder JM, Child SJ, Geballe AP, Stetson DB.

Immunity. 2016 Aug 16;45(2):255-66. doi: 10.1016/j.immuni.2016.06.015. Epub 2016 Aug 2.

13.

Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.

York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ.

Cell. 2015 Dec 17;163(7):1716-29. doi: 10.1016/j.cell.2015.11.045. Epub 2015 Dec 10.

14.

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development.

Pestal K, Funk CC, Snyder JM, Price ND, Treuting PM, Stetson DB.

Immunity. 2015 Nov 17;43(5):933-44. doi: 10.1016/j.immuni.2015.11.001.

15.

DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway.

Lau L, Gray EE, Brunette RL, Stetson DB.

Science. 2015 Oct 30;350(6260):568-71. doi: 10.1126/science.aab3291. Epub 2015 Sep 24.

16.

Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome.

Gray EE, Treuting PM, Woodward JJ, Stetson DB.

J Immunol. 2015 Sep 1;195(5):1939-43. doi: 10.4049/jimmunol.1500969. Epub 2015 Jul 29.

17.

Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M.

Thress KS, Paweletz CP, Felip E, Cho BC, Stetson D, Dougherty B, Lai Z, Markovets A, Vivancos A, Kuang Y, Ercan D, Matthews SE, Cantarini M, Barrett JC, Jänne PA, Oxnard GR.

Nat Med. 2015 Jun;21(6):560-2. doi: 10.1038/nm.3854. Epub 2015 May 4.

18.

Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.

Eberlein CA, Stetson D, Markovets AA, Al-Kadhimi KJ, Lai Z, Fisher PR, Meador CB, Spitzler P, Ichihara E, Ross SJ, Ahdesmaki MJ, Ahmed A, Ratcliffe LE, O'Brien EL, Barnes CH, Brown H, Smith PD, Dry JR, Beran G, Thress KS, Dougherty B, Pao W, Cross DA.

Cancer Res. 2015 Jun 15;75(12):2489-500. doi: 10.1158/0008-5472.CAN-14-3167. Epub 2015 Apr 13.

19.

The SKIV2L RNA exosome limits activation of the RIG-I-like receptors.

Eckard SC, Rice GI, Fabre A, Badens C, Gray EE, Hartley JL, Crow YJ, Stetson DB.

Nat Immunol. 2014 Sep;15(9):839-45. doi: 10.1038/ni.2948. Epub 2014 Jul 27.

20.

The enemy within: endogenous retroelements and autoimmune disease.

Volkman HE, Stetson DB.

Nat Immunol. 2014 May;15(5):415-22. doi: 10.1038/ni.2872. Review.

21.

Endogenous retroelements and autoimmune disease.

Stetson DB.

Curr Opin Immunol. 2012 Dec;24(6):692-7. doi: 10.1016/j.coi.2012.09.007. Epub 2012 Oct 10. Review.

22.

Extensive evolutionary and functional diversity among mammalian AIM2-like receptors.

Brunette RL, Young JM, Whitley DG, Brodsky IE, Malik HS, Stetson DB.

J Exp Med. 2012 Oct 22;209(11):1969-83. doi: 10.1084/jem.20121960. Epub 2012 Oct 8.

23.

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease.

Gall A, Treuting P, Elkon KB, Loo YM, Gale M Jr, Barber GN, Stetson DB.

Immunity. 2012 Jan 27;36(1):120-31. doi: 10.1016/j.immuni.2011.11.018.

24.

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response.

Rice GI, Bond J, Asipu A, Brunette RL, Manfield IW, Carr IM, Fuller JC, Jackson RM, Lamb T, Briggs TA, Ali M, Gornall H, Couthard LR, Aeby A, Attard-Montalto SP, Bertini E, Bodemer C, Brockmann K, Brueton LA, Corry PC, Desguerre I, Fazzi E, Cazorla AG, Gener B, Hamel BC, Heiberg A, Hunter M, van der Knaap MS, Kumar R, Lagae L, Landrieu PG, Lourenco CM, Marom D, McDermott MF, van der Merwe W, Orcesi S, Prendiville JS, Rasmussen M, Shalev SA, Soler DM, Shinawi M, Spiegel R, Tan TY, Vanderver A, Wakeling EL, Wassmer E, Whittaker E, Lebon P, Stetson DB, Bonthron DT, Crow YJ.

Nat Genet. 2009 Jul;41(7):829-32. doi: 10.1038/ng.373. Epub 2009 Jun 14.

25.

Connections between antiviral defense and autoimmunity.

Stetson DB.

Curr Opin Immunol. 2009 Jun;21(3):244-50. doi: 10.1016/j.coi.2009.05.005. Epub 2009 Jun 3. Review.

26.

Trex1 prevents cell-intrinsic initiation of autoimmunity.

Stetson DB, Ko JS, Heidmann T, Medzhitov R.

Cell. 2008 Aug 22;134(4):587-98. doi: 10.1016/j.cell.2008.06.032.

27.

T helper 17 cells get the NOD.

Stetson DB, Medzhitov R.

Immunity. 2007 Oct;27(4):546-8. Review.

28.

Type I interferons in host defense.

Stetson DB, Medzhitov R.

Immunity. 2006 Sep;25(3):373-81. Review.

29.

Antiviral defense: interferons and beyond.

Stetson DB, Medzhitov R.

J Exp Med. 2006 Aug 7;203(8):1837-41. Epub 2006 Jul 31. Erratum in: J Exp Med. 2006 Sep 4;203(9):2215.

30.

Activation of the integrated stress response during T helper cell differentiation.

Scheu S, Stetson DB, Reinhardt RL, Leber JH, Mohrs M, Locksley RM.

Nat Immunol. 2006 Jun;7(6):644-51. Epub 2006 May 7.

PMID:
16680145
31.

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response.

Stetson DB, Medzhitov R.

Immunity. 2006 Jan;24(1):93-103.

32.

Th2 cells: orchestrating barrier immunity.

Stetson DB, Voehringer D, Grogan JL, Xu M, Reinhardt RL, Scheu S, Kelly BL, Locksley RM.

Adv Immunol. 2004;83:163-89. Review. No abstract available.

PMID:
15135631
33.

Leishmania major LACK antigen is required for efficient vertebrate parasitization.

Kelly BL, Stetson DB, Locksley RM.

J Exp Med. 2003 Dec 1;198(11):1689-98.

34.

Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function.

Stetson DB, Mohrs M, Reinhardt RL, Baron JL, Wang ZE, Gapin L, Kronenberg M, Locksley RM.

J Exp Med. 2003 Oct 6;198(7):1069-76.

35.

Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo.

Matsuda JL, Gapin L, Baron JL, Sidobre S, Stetson DB, Mohrs M, Locksley RM, Kronenberg M.

Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8395-400. Epub 2003 Jun 26.

36.

Analysis of Ras-induced overproliferation in Drosophila hemocytes.

Asha H, Nagy I, Kovacs G, Stetson D, Ando I, Dearolf CR.

Genetics. 2003 Jan;163(1):203-15.

37.

Rapid expansion and IL-4 expression by Leishmania-specific naive helper T cells in vivo.

Stetson DB, Mohrs M, Mallet-Designe V, Teyton L, Locksley RM.

Immunity. 2002 Aug;17(2):191-200.

38.

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

Riese RJ, Shi GP, Villadangos J, Stetson D, Driessen C, Lennon-Dumenil AM, Chu CL, Naumov Y, Behar SM, Ploegh H, Locksley R, Chapman HA.

Immunity. 2001 Dec;15(6):909-19.

39.

Development and maintenance of a B220- memory B cell compartment.

Driver DJ, McHeyzer-Williams LJ, Cool M, Stetson DB, McHeyzer-Williams MG.

J Immunol. 2001 Aug 1;167(3):1393-405.

40.

Effects of intermittent ischemia on contractile properties and myosin isoforms of skeletal muscle.

Dodd SL, Vrabas IS, Stetson DS.

Med Sci Sports Exerc. 1998 Jun;30(6):850-5.

PMID:
9624642
41.

Work-related musculoskeletal disorders: comparison of data sources for surveillance.

Silverstein BA, Stetson DS, Keyserling WM, Fine LJ.

Am J Ind Med. 1997 May;31(5):600-8.

42.

The CPR: getting physicians on board.

Stetson D, Andrew W.

Healthc Inform. 1996 Jun;13(6):20, 22, 24.

PMID:
10161402
43.

Hypothesis relating cumulative trauma to the median nerve with sub-clinical nerve conduction deficits.

Stetson DS, Silverstein BA, Keyserling WM, Wolfe WA, Albers JW.

Am J Ind Med. 1995 Feb;27(2):309-10. No abstract available.

PMID:
7755021
44.

Computers as clinical consultants.

Stetson DM.

Contemp Pediatr. 1994 Jun;11(6):52-4, 57-60, 64-8. No abstract available.

PMID:
10147361
45.

Median sensory distal amplitude and latency: comparisons between nonexposed managerial/professional employees and industrial workers.

Stetson DS, Silverstein BA, Keyserling WM, Wolfe RA, Albers JW.

Am J Ind Med. 1993 Aug;24(2):175-89.

PMID:
8213845
46.

A checklist for evaluating ergonomic risk factors associated with upper extremity cumulative trauma disorders.

Keyserling WM, Stetson DS, Silverstein BA, Brouwer ML.

Ergonomics. 1993 Jul;36(7):807-31.

PMID:
8339720
47.

Cellular differences in ring glands of flesh fly pupae as a consequence of diapause programming.

Joplin KH, Stetson DL, Diaz JG, Denlinger DL.

Tissue Cell. 1993 Apr;25(2):245-57.

PMID:
18621232
48.

Effects of age, sex, and anthropometric factors on nerve conduction measures.

Stetson DS, Albers JW, Silverstein BA, Wolfe RA.

Muscle Nerve. 1992 Oct;15(10):1095-104.

49.

Contribution of renal medullary mitochondrial density to urinary concentrating ability in mammals.

Abrahams S, Greenwald L, Stetson DL.

Am J Physiol. 1991 Sep;261(3 Pt 2):R719-26.

PMID:
1887960
50.

Ultrastructural characteristics of a cell line derived from a melanotic neuroectodermal tumor of infancy.

Claman LJ, Stetson D, Steinberg B, Shuler CF.

J Oral Pathol Med. 1991 May;20(5):245-9.

PMID:
1648614

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