Sort by
Items per page

Send to

Choose Destination

Search results

Items: 35


Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab.

Sternlicht MD, Wirkner U, Bickelhaupt S, Lopez Perez R, Tietz A, Lipson KE, Seeley TW, Huber PE.

Respir Res. 2018 Jan 18;19(1):14. doi: 10.1186/s12931-018-0720-4.


Effects of CTGF Blockade on Attenuation and Reversal of Radiation-Induced Pulmonary Fibrosis.

Bickelhaupt S, Erbel C, Timke C, Wirkner U, Dadrich M, Flechsig P, Tietz A, Pföhler J, Gross W, Peschke P, Hoeltgen L, Katus HA, Gröne HJ, Nicolay NH, Saffrich R, Debus J, Sternlicht MD, Seeley TW, Lipson KE, Huber PE.

J Natl Cancer Inst. 2017 Aug 1;109(8). doi: 10.1093/jnci/djw339.


FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition.

Brenner MC, Krzyzanski W, Chou JZ, Signore PE, Fung CK, Guzman D, Li D, Zhang W, Olsen DR, Nguyen VT, Koo CW, Sternlicht MD, Lipson KE.

Pharm Res. 2016 Aug;33(8):1833-49. doi: 10.1007/s11095-016-1918-0. Epub 2016 Apr 8.


Connective tissue growth factor regulates cardiac function and tissue remodeling in a mouse model of dilated cardiomyopathy.

Koshman YE, Sternlicht MD, Kim T, O'Hara CP, Koczor CA, Lewis W, Seeley TW, Lipson KE, Samarel AM.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):214-22. doi: 10.1016/j.yjmcc.2015.11.003. Epub 2015 Nov 5.


CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer.

Neesse A, Frese KK, Bapiro TE, Nakagawa T, Sternlicht MD, Seeley TW, Pilarsky C, Jodrell DI, Spong SM, Tuveson DA.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30. doi: 10.1073/pnas.1300415110. Epub 2013 Jul 8.


The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.

Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z.

Cancer Discov. 2012 Jul;2(7):638-51. doi: 10.1158/2159-8290.CD-12-0093. Epub 2012 May 10.


Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression.

Littlepage LE, Sternlicht MD, Rougier N, Phillips J, Gallo E, Yu Y, Williams K, Brenot A, Gordon JI, Werb Z.

Cancer Res. 2010 Mar 15;70(6):2224-34. doi: 10.1158/0008-5472.CAN-09-3515. Epub 2010 Mar 9.


Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.

Tranah GJ, Taylor BC, Lui LY, Zmuda JM, Cauley JA, Ensrud KE, Hillier TA, Hochberg MC, Li J, Rhees BK, Erlich HA, Sternlicht MD, Peltz G, Cummings SR; Study of Osteoporotic Fractures (SOF) Research Group.

Calcif Tissue Int. 2008 Sep;83(3):155-66. doi: 10.1007/s00223-008-9165-y. Epub 2008 Sep 12.


The ADAM17-amphiregulin-EGFR axis in mammary development and cancer.

Sternlicht MD, Sunnarborg SW.

J Mammary Gland Biol Neoplasia. 2008 Jun;13(2):181-94. doi: 10.1007/s10911-008-9084-6. Epub 2008 May 10. Review.


GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland.

Kouros-Mehr H, Slorach EM, Sternlicht MD, Werb Z.

Cell. 2006 Dec 1;127(5):1041-55.


Comparative mechanisms of branching morphogenesis in diverse systems.

Lu P, Sternlicht MD, Werb Z.

J Mammary Gland Biol Neoplasia. 2006 Oct;11(3-4):213-28. Review.


Prognostic value of PAI1 in invasive breast cancer: evidence that tumor-specific factors are more important than genetic variation in regulating PAI1 expression.

Sternlicht MD, Dunning AM, Moore DH, Pharoah PD, Ginzinger DG, Chin K, Gray JW, Waldman FM, Ponder BA, Werb Z.

Cancer Epidemiol Biomarkers Prev. 2006 Nov;15(11):2107-14.


Hormonal and local control of mammary branching morphogenesis.

Sternlicht MD, Kouros-Mehr H, Lu P, Werb Z.

Differentiation. 2006 Sep;74(7):365-81. Review.


Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia.

Gudjonsson T, Adriance MC, Sternlicht MD, Petersen OW, Bissell MJ.

J Mammary Gland Biol Neoplasia. 2005 Jul;10(3):261-72. Review.


Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis.

Sternlicht MD.

Breast Cancer Res. 2006;8(1):201. Epub 2005 Dec 5. Review.


Epimorphin overexpression in the mouse mammary gland promotes alveolar hyperplasia and mammary adenocarcinoma.

Bascom JL, Fata JE, Hirai Y, Sternlicht MD, Bissell MJ.

Cancer Res. 2005 Oct 1;65(19):8617-21.


Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin.

Sternlicht MD, Sunnarborg SW, Kouros-Mehr H, Yu Y, Lee DC, Werb Z.

Development. 2005 Sep;132(17):3923-33. Epub 2005 Aug 3. Erratum in: Development. 2006 Mar;133(6):1203.


Matrix metalloproteinase-2 contributes to cancer cell migration on collagen.

Xu X, Wang Y, Chen Z, Sternlicht MD, Hidalgo M, Steffensen B.

Cancer Res. 2005 Jan 1;65(1):130-6.


Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis.

Wiseman BS, Sternlicht MD, Lund LR, Alexander CM, Mott J, Bissell MJ, Soloway P, Itohara S, Werb Z.

J Cell Biol. 2003 Sep 15;162(6):1123-33.


How matrix metalloproteinases regulate cell behavior.

Sternlicht MD, Werb Z.

Annu Rev Cell Dev Biol. 2001;17:463-516. Review.


Lactational competence and involution of the mouse mammary gland require plasminogen.

Lund LR, Bjørn SF, Sternlicht MD, Nielsen BS, Solberg H, Usher PA, Osterby R, Christensen IJ, Stephens RW, Bugge TH, Danø K, Werb Z.

Development. 2000 Oct;127(20):4481-92.


The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter.

Sternlicht MD, Bissell MJ, Werb Z.

Oncogene. 2000 Feb 21;19(8):1102-13. Review.


The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis.

Sternlicht MD, Lochter A, Sympson CJ, Huey B, Rougier JP, Gray JW, Pinkel D, Bissell MJ, Werb Z.

Cell. 1999 Jul 23;98(2):137-46.


The significance of matrix metalloproteinases during early stages of tumor progression.

Lochter A, Sternlicht MD, Werb Z, Bissell MJ.

Ann N Y Acad Sci. 1998 Oct 23;857:180-93. Review.


The human myoepithelial cell is a natural tumor suppressor.

Sternlicht MD, Kedeshian P, Shao ZM, Safarians S, Barsky SH.

Clin Cancer Res. 1997 Nov;3(11):1949-58.


Humatrix, a novel myoepithelial matrical gel with unique biochemical and biological properties.

Kedeshian P, Sternlicht MD, Nguyen M, Shao ZM, Barsky SH.

Cancer Lett. 1998 Jan 30;123(2):215-26.


'Revertant' DCIS in human axillary breast carcinoma metastases.

Barsky SH, Doberneck SA, Sternlicht MD, Grossman DA, Love SM.

J Pathol. 1997 Oct;183(2):188-94.


Evidence of a dominant transcriptional pathway which regulates an undifferentiated and complete metastatic phenotype.

Barsky SH, Sternlicht MD, Safarians S, Nguyen M, Chin K, Stewart SD, Hiti AL, Gray JW.

Oncogene. 1997 Oct 23;15(17):2077-91.


Ectopic G-CSF expression in human melanoma lines marks a trans-dominant pathway of tumor progression.

Safarians S, Rivera SP, Sternlicht MD, Naeim F, Barsky SH.

Am J Pathol. 1997 Mar;150(3):949-62.


The myoepithelial defense: a host defense against cancer.

Sternlicht MD, Barsky SH.

Med Hypotheses. 1997 Jan;48(1):37-46.


Establishment and characterization of a novel human myoepithelial cell line and matrix-producing xenograft from a parotid basal cell adenocarcinoma.

Sternlicht MD, Safarians S, Calcaterra TC, Barsky SH.

In Vitro Cell Dev Biol Anim. 1996 Oct;32(9):550-63.


Human breast cancer progression can be regulated by dominant trans-acting factors in somatic cell hybridization studies.

Safarians S, Sternlicht MD, Yamanishi DT, Love SM, Barsky SH.

Cancer Res. 1996 Aug 1;56(15):3560-9.


Characterizations of the extracellular matrix and proteinase inhibitor content of human myoepithelial tumors.

Sternlicht MD, Safarians S, Rivera SP, Barsky SH.

Lab Invest. 1996 Apr;74(4):781-96.


Supplemental Content

Loading ...
Support Center