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A new device to prevent fascial retraction in the open abdomen - proof of concept in vivo.

Eickhoff R, Guschlbauer M, Maul AC, Klink CD, Neumann UP, Engel M, Hellmich M, Sterner-Kock A, Krieglstein CF.

BMC Surg. 2019 Jul 8;19(1):82. doi: 10.1186/s12893-019-0543-3.


Experimental Studies for Small Diameter Grafts in an In Vivo Sheep Model-Techniques and Pitfalls.

Eghbalzadeh K, Guschlbauer M, Weber C, Wacker MT, Reinhardt S, Djordjevic I, Sabashnikov A, Maul A, Sterner-Kock A, Wahlers TCW, Scherner M, Wippermann J.

Thorac Cardiovasc Surg. 2019 Apr 28. doi: 10.1055/s-0039-1687887. [Epub ahead of print]


Esophageal Heat Exchanger Versus Water-Circulating Cooling Blanket for Targeted Temperature Management.

Schroeder DC, Maul AC, Guschlbauer M, Finke SR, de la Puente Bethencourt D, Neumann T, Padosch SA, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

Ther Hypothermia Temp Manag. 2019 Dec;9(4):251-257. doi: 10.1089/ther.2018.0054. Epub 2019 Mar 20.


Intravascular Cooling Device Versus Esophageal Heat Exchanger for Mild Therapeutic Hypothermia in an Experimental Setting.

Schroeder DC, Maul AC, Guschlbauer M, Finke SR, de la Puente Bethencourt D, Becker I, Padosch SA, Hohn A, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

Anesth Analg. 2019 Nov;129(5):1224-1231. doi: 10.1213/ANE.0000000000003922.


Evaluation of small intestinal damage in a rat model of 6 Minutes cardiac arrest.

Schroeder DC, Maul AC, Mahabir E, Koxholt I, Yan X, Padosch SA, Herff H, Bultmann-Mellin I, Sterner-Kock A, Annecke T, Hucho T, Böttiger BW, Guschlbauer M.

BMC Anesthesiol. 2018 Jun 5;18(1):61. doi: 10.1186/s12871-018-0530-8.


Patency and in vivo compatibility of bacterial nanocellulose grafts as small-diameter vascular substitute.

Weber C, Reinhardt S, Eghbalzadeh K, Wacker M, Guschlbauer M, Maul A, Sterner-Kock A, Wahlers T, Wippermann J, Scherner M.

J Vasc Surg. 2018 Dec;68(6S):177S-187S.e1. doi: 10.1016/j.jvs.2017.09.038. Epub 2017 Dec 18.


Stereological assessment of the blood-air barrier and the surfactant system after mesenchymal stem cell pretreatment in a porcine non-heart-beating donor model for lung transplantation.

Schnapper A, Christmann A, Knudsen L, Rahmanian P, Choi YH, Zeriouh M, Karavidic S, Neef K, Sterner-Kock A, Guschlbauer M, Hofmaier F, Maul AC, Wittwer T, Wahlers T, Mühlfeld C, Ochs M.

J Anat. 2018 Feb;232(2):283-295. doi: 10.1111/joa.12747. Epub 2017 Nov 28.


Metformin causes a futile intestinal-hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state.

Schommers P, Thurau A, Bultmann-Mellin I, Guschlbauer M, Klatt AR, Rozman J, Klingenspor M, de Angelis MH, Alber J, Gründemann D, Sterner-Kock A, Wiesner RJ.

Mol Metab. 2017 May 5;6(7):737-747. doi: 10.1016/j.molmet.2017.05.002. eCollection 2017 Jul.


Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.

Bultmann-Mellin I, Dinger K, Debuschewitz C, Loewe KMA, Melcher Y, Plum MTW, Appel S, Rappl G, Willenborg S, Schauss AC, Jüngst C, Krüger M, Dressler S, Nakamura T, Wempe F, Alejandre Alcázar MA, Sterner-Kock A.

Am J Physiol Lung Cell Mol Physiol. 2017 Oct 1;313(4):L687-L698. doi: 10.1152/ajplung.00031.2017. Epub 2017 Jul 6.


Oesophageal heat exchangers with a diameter of 11mm or 14.7mm are equally effective and safe for targeted temperature management.

Schroeder DC, Guschlbauer M, Maul AC, Cremer DA, Becker I, de la Puente Bethencourt D, Paal P, Padosch SA, Wetsch WA, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

PLoS One. 2017 Mar 14;12(3):e0173229. doi: 10.1371/journal.pone.0173229. eCollection 2017.


Ltbp4 regulates Pdgfrβ expression via TGFβ-dependent modulation of Nrf2 transcription factor function.

Tomasovic A, Kurrle N, Wempe F, De-Zolt S, Scheibe S, Koli K, Serchinger M, Schnütgen F, Sürün D, Sterner-Kock A, Weissmann N, von Melchner H.

Matrix Biol. 2017 May;59:109-120. doi: 10.1016/j.matbio.2016.09.006. Epub 2016 Sep 17.


Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice.

Bultmann-Mellin I, Essers J, van Heijingen PM, von Melchner H, Sengle G, Sterner-Kock A.

Dis Model Mech. 2016 Nov 1;9(11):1367-1374. Epub 2016 Sep 1.


Zero-Heat-Flux Thermometry for Non-Invasive Measurement of Core Body Temperature in Pigs.

Guschlbauer M, Maul AC, Yan X, Herff H, Annecke T, Sterner-Kock A, Böttiger BW, Schroeder DC.

PLoS One. 2016 Mar 3;11(3):e0150759. doi: 10.1371/journal.pone.0150759. eCollection 2016.


Morphological characterization and immunohistochemical detection of the proinflammatory cytokines IL-1β, IL-17A, and TNF-α in lung lesions associated with contagious bovine pleuropneumonia.

Sterner-Kock A, Haider W, Sacchini F, Liljander A, Meens J, Poole J, Guschlbauer M, Heller M, Naessens J, Jores J.

Trop Anim Health Prod. 2016 Mar;48(3):569-76. doi: 10.1007/s11250-016-0994-9. Epub 2016 Feb 2.


The fibronectin/α3β1 integrin axis serves as molecular basis for keratinocyte invasion induced by βHPV.

Heuser S, Hufbauer M, Steiger J, Marshall J, Sterner-Kock A, Mauch C, Zigrino P, Akgül B.

Oncogene. 2016 Aug 25;35(34):4529-39. doi: 10.1038/onc.2015.512. Epub 2016 Jan 25.


Prenatal exposure to the phytoestrogen daidzein resulted in persistent changes in ovarian surface epithelial cell height, folliculogenesis, and estrus phase length in adult Sprague-Dawley rat offspring.

Talsness C, Grote K, Kuriyama S, Presibella K, Sterner-Kock A, Poça K, Chahoud I.

J Toxicol Environ Health A. 2015;78(10):635-44. doi: 10.1080/15287394.2015.1006711.


Erratum: Mesenchymal stem cell pretreatment of non-heart-beating-donors in experimental lung transplantation.

Wittwer T, Rahmanian P, Choi YH, Zeriouh M, Karavidic S, Neef K, Christmann A, Piatkowski T, Schnapper A, Ochs M, Mühlfeld C, Sterner-Kock A, Guschlbauer M, Hofmaier F, Maul AC, Wahlers T.

J Cardiothorac Surg. 2015 May 21;10:75. doi: 10.1186/s13019-014-0198-1. No abstract available.


Class IA Phosphatidylinositol 3-Kinase Isoform p110α Mediates Vascular Remodeling.

Vantler M, Jesus J, Leppänen O, Scherner M, Berghausen EM, Mustafov L, Chen X, Kramer T, Zierden M, Gerhardt M, Ten Freyhaus H, Blaschke F, Sterner-Kock A, Baldus S, Zhao JJ, Rosenkranz S.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1434-44. doi: 10.1161/ATVBAHA.114.304887. Epub 2015 Apr 23.


Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms.

Bultmann-Mellin I, Conradi A, Maul AC, Dinger K, Wempe F, Wohl AP, Imhof T, Wunderlich FT, Bunck AC, Nakamura T, Koli K, Bloch W, Ghanem A, Heinz A, von Melchner H, Sengle G, Sterner-Kock A.

Dis Model Mech. 2015 Apr;8(4):403-15. doi: 10.1242/dmm.018960. Epub 2015 Feb 20.


Controlled lung reperfusion to reduce pulmonary ischaemia/reperfusion injury after cardiopulmonary bypass in a porcine model.

Slottosch I, Liakopoulos O, Kuhn E, Deppe A, Lopez-Pastorini A, Schwarz D, Neef K, Choi YH, Sterner-Kock A, Jung K, Mühlfeld C, Wahlers T.

Interact Cardiovasc Thorac Surg. 2014 Dec;19(6):962-70. doi: 10.1093/icvts/ivu270. Epub 2014 Aug 20. Erratum in: Interact Cardiovasc Thorac Surg. 2015 Apr;20(4):567. Sterner-Kock, Anja [added].


BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.

Andree M, Seeger JM, Schüll S, Coutelle O, Wagner-Stippich D, Wiegmann K, Wunderlich CM, Brinkmann K, Broxtermann P, Witt A, Fritsch M, Martinelli P, Bielig H, Lamkemeyer T, Rugarli EI, Kaufmann T, Sterner-Kock A, Wunderlich FT, Villunger A, Martins LM, Krönke M, Kufer TA, Utermöhlen O, Kashkar H.

EMBO J. 2014 Oct 1;33(19):2171-87. doi: 10.15252/embj.201387244. Epub 2014 Jul 23.


High antibody titres against predicted Mycoplasma surface proteins do not prevent sequestration in infected lung tissue in the course of experimental contagious bovine pleuropneumonia.

Schieck E, Liljander A, Hamsten C, Gicheru N, Scacchia M, Sacchini F, Heller M, Schnee C, Sterner-Kock A, Hlinak A, Naessens J, Poole J, Persson A, Jores J.

Vet Microbiol. 2014 Aug 6;172(1-2):285-93. doi: 10.1016/j.vetmic.2014.04.018. Epub 2014 May 5.


In vivo application of tissue-engineered blood vessels of bacterial cellulose as small arterial substitutes: proof of concept?

Scherner M, Reutter S, Klemm D, Sterner-Kock A, Guschlbauer M, Richter T, Langebartels G, Madershahian N, Wahlers T, Wippermann J.

J Surg Res. 2014 Jun 15;189(2):340-7. doi: 10.1016/j.jss.2014.02.011. Epub 2014 Feb 15.


Latent transforming growth factor β-binding protein 4 is downregulated in esophageal cancer via promoter methylation.

Bultmann I, Conradi A, Kretschmer C, Sterner-Kock A.

PLoS One. 2013 May 31;8(5):e65614. doi: 10.1371/journal.pone.0065614. Print 2013.


Range of blood lactate values in farm pigs prior to experimental surgery.

Hofmaier F, Dinger K, Braun R, Sterner-Kock A.

Lab Anim. 2013 Apr;47(2):130-2. doi: 10.1177/0023677213476857. Epub 2013 Mar 11.


Rosuvastatin reloading before cardiac surgery with cardiopulmonary bypass.

Kuhn EW, Liakopoulos OJ, Deppe AC, Slottosch I, Neef K, Sterner-Kock A, Madershahian N, Choi YH, Wahlers T.

Eur Surg Res. 2013;50(1):1-13. doi: 10.1159/000345448. Epub 2013 Feb 12.


Severe SMA mice show organ impairment that cannot be rescued by therapy with the HDACi JNJ-26481585.

Schreml J, Riessland M, Paterno M, Garbes L, Roßbach K, Ackermann B, Krämer J, Somers E, Parson SH, Heller R, Berkessel A, Sterner-Kock A, Wirth B.

Eur J Hum Genet. 2013 Jun;21(6):643-52. doi: 10.1038/ejhg.2012.222. Epub 2012 Oct 17.


Evaluation of the use of lower body perfusion at 28°C in aortic arch surgery.

Haldenwang PL, Klein T, Neef K, Riet T, Sterner-Kock A, Christ H, Wahlers T, Strauch JT.

Eur J Cardiothorac Surg. 2012 May;41(5):e100-8; discussion e108-9. doi: 10.1093/ejcts/ezs079. Epub 2012 Mar 20.


FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernández-Majada V, Ermolaeva M, Kirsch P, Sterner-Kock A, van Loo G, Pasparakis M.

Nature. 2011 Jul 31;477(7364):330-4. doi: 10.1038/nature10273.


A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. mycoides.

Sacchini F, Naessens J, Awino E, Heller M, Hlinak A, Haider W, Sterner-Kock A, Jores J.

Vet Res. 2011 Jun 12;42:77. doi: 10.1186/1297-9716-42-77.


Latent transforming growth factor binding protein 4 (LTBP4) is downregulated in mouse and human DCIS and mammary carcinomas.

Kretschmer C, Conradi A, Kemmner W, Sterner-Kock A.

Cell Oncol (Dordr). 2011 Oct;34(5):419-34. doi: 10.1007/s13402-011-0023-y. Epub 2011 Apr 6.


Identification of early molecular markers for breast cancer.

Kretschmer C, Sterner-Kock A, Siedentopf F, Schoenegg W, Schlag PM, Kemmner W.

Mol Cancer. 2011 Feb 11;10(1):15. doi: 10.1186/1476-4598-10-15.


Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure.

Yin J, Kukucka M, Hoffmann J, Sterner-Kock A, Burhenne J, Haefeli WE, Kuppe H, Kuebler WM.

Circ Heart Fail. 2011 Mar;4(2):198-206. doi: 10.1161/CIRCHEARTFAILURE.110.957050. Epub 2011 Jan 7. Erratum in: Circ Heart Fail. 2011 May 1;4(3):e13.


Mast cells promote lung vascular remodelling in pulmonary hypertension.

Hoffmann J, Yin J, Kukucka M, Yin N, Saarikko I, Sterner-Kock A, Fujii H, Leong-Poi H, Kuppe H, Schermuly RT, Kuebler WM.

Eur Respir J. 2011 Jun;37(6):1400-10. doi: 10.1183/09031936.00043310. Epub 2010 Dec 9. Erratum in: Eur Respir J. 2012 Aug;40(2):515-7.


Impact of pump flow rate during selective cerebral perfusion on cerebral hemodynamics and metabolism.

Haldenwang PL, Strauch JT, Amann I, Klein T, Sterner-Kock A, Christ H, Wahlers T.

Ann Thorac Surg. 2010 Dec;90(6):1975-84. doi: 10.1016/j.athoracsur.2010.06.111.


Inactivation of sestrin 2 induces TGF-beta signaling and partially rescues pulmonary emphysema in a mouse model of COPD.

Wempe F, De-Zolt S, Koli K, Bangsow T, Parajuli N, Dumitrascu R, Sterner-Kock A, Weissmann N, Keski-Oja J, von Melchner H.

Dis Model Mech. 2010 Mar-Apr;3(3-4):246-53. doi: 10.1242/dmm.004234. Epub 2010 Jan 27.


Cardiac phenotype and angiotensin II levels in AT1a, AT1b, and AT2 receptor single, double, and triple knockouts.

van Esch JH, Gembardt F, Sterner-Kock A, Heringer-Walther S, Le TH, Lassner D, Stijnen T, Coffman TM, Schultheiss HP, Danser AH, Walther T.

Cardiovasc Res. 2010 Jun 1;86(3):401-9. doi: 10.1093/cvr/cvq004. Epub 2010 Jan 12.


Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation.

Esteban V, Heringer-Walther S, Sterner-Kock A, de Bruin R, van den Engel S, Wang Y, Mezzano S, Egido J, Schultheiss HP, Ruiz-Ortega M, Walther T.

PLoS One. 2009;4(4):e5406. doi: 10.1371/journal.pone.0005406. Epub 2009 Apr 30.


Improved learning and memory in aged mice deficient in amyloid beta-degrading neutral endopeptidase.

Walther T, Albrecht D, Becker M, Schubert M, Kouznetsova E, Wiesner B, Maul B, Schliebs R, Grecksch G, Furkert J, Sterner-Kock A, Schultheiss HP, Becker A, Siems WE.

PLoS One. 2009;4(2):e4590. doi: 10.1371/journal.pone.0004590. Epub 2009 Feb 25.


Excessive hypertension and end-organ damage in a transgenic mouse line carrying the rat angiotensinogen gene.

Xu P, Wang Y, Sterner-Kock A, Bader M, Schultheiss HP, Walther T.

J Cardiovasc Pharmacol. 2009 Jan;53(1):38-43. doi: 10.1097/FJC.0b013e3181953e44.


Myocardial overexpression of adenine nucleotide translocase 1 ameliorates diabetic cardiomyopathy in mice.

Wang Y, Ebermann L, Sterner-Kock A, Wika S, Schultheiss HP, Dörner A, Walther T.

Exp Physiol. 2009 Feb;94(2):220-7. doi: 10.1113/expphysiol.2008.044800. Epub 2008 Oct 22.


Cardiovascular phenotype of mice lacking all three subtypes of angiotensin II receptors.

Gembardt F, Heringer-Walther S, van Esch JH, Sterner-Kock A, van Veghel R, Le TH, Garrelds IM, Coffman TM, Danser AH, Schultheiss HP, Walther T.

FASEB J. 2008 Aug;22(8):3068-77. doi: 10.1096/fj.08-108316. Epub 2008 May 22.


Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type.

Jores J, Nkando I, Sterner-Kock A, Haider W, Poole J, Unger H, Muriuki C, Wesonga H, Taracha EL.

Vet Immunol Immunopathol. 2008 Jul 15;124(1-2):192-7. doi: 10.1016/j.vetimm.2008.02.019. Epub 2008 Mar 6.


IL-17 producing gammadelta T cells are required for a controlled inflammatory response after bleomycin-induced lung injury.

Braun RK, Ferrick C, Neubauer P, Sjoding M, Sterner-Kock A, Kock M, Putney L, Ferrick DA, Hyde DM, Love RB.

Inflammation. 2008 Jun;31(3):167-79. doi: 10.1007/s10753-008-9062-6. Epub 2008 Mar 13.


Impaired spatial memory and altered dendritic spine morphology in angiotensin II type 2 receptor-deficient mice.

Maul B, von Bohlen und Halbach O, Becker A, Sterner-Kock A, Voigt JP, Siems WE, Grecksch G, Walther T.

J Mol Med (Berl). 2008 May;86(5):563-71. doi: 10.1007/s00109-008-0316-4. Epub 2008 Mar 12.


In utero and lactational exposures to low doses of polybrominated diphenyl ether-47 alter the reproductive system and thyroid gland of female rat offspring.

Talsness CE, Kuriyama SN, Sterner-Kock A, Schnitker P, Grande SW, Shakibaei M, Andrade A, Grote K, Chahoud I.

Environ Health Perspect. 2008 Mar;116(3):308-14. doi: 10.1289/ehp.10536.


Latent transforming growth factor binding protein 4 (LTBP-4) is downregulated in human mammary adenocarcinomas in vitro and in vivo.

Mauel S, Kruse B, Etschmann B, von der Schulenburg AG, Schaerig M, Stövesand K, Wilcken B, Sterner-Kock A.

APMIS. 2007 Jun;115(6):687-700.


Cardiomyocyte-restricted over-expression of C-type natriuretic peptide prevents cardiac hypertrophy induced by myocardial infarction in mice.

Wang Y, de Waard MC, Sterner-Kock A, Stepan H, Schultheiss HP, Duncker DJ, Walther T.

Eur J Heart Fail. 2007 Jun-Jul;9(6-7):548-57. Epub 2007 Apr 3.


Accelerated mitochondrial adenosine diphosphate/adenosine triphosphate transport improves hypertension-induced heart disease.

Walther T, Tschöpe C, Sterner-Kock A, Westermann D, Heringer-Walther S, Riad A, Nikolic A, Wang Y, Ebermann L, Siems WE, Bader M, Shakibaei M, Schultheiss HP, Dörner A.

Circulation. 2007 Jan 23;115(3):333-44. Epub 2007 Jan 8.


Selection of reference genes for quantitative real-time PCR analysis in canine mammary tumors using the GeNorm algorithm.

Etschmann B, Wilcken B, Stoevesand K, von der Schulenburg A, Sterner-Kock A.

Vet Pathol. 2006 Nov;43(6):934-42.


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