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Items: 1 to 50 of 537


An Efficient Genome Editing Strategy To Generate Putative Null Mutants in Caenorhabditis elegans Using CRISPR/Cas9.

Wang H, Park H, Liu J, Sternberg PW.

G3 (Bethesda). 2018 Nov 6;8(11):3607-3616. doi: 10.1534/g3.118.200662.


An EPIC Switch: Observations and Opportunities After Go-Live.

Johnson KB, Sternberg P Jr, Dubree M.

J Med Syst. 2018 Aug 11;42(9):174. doi: 10.1007/s10916-018-1023-5. No abstract available.


Biology and genome of a newly discovered sibling species of Caenorhabditis elegans.

Kanzaki N, Tsai IJ, Tanaka R, Hunt VL, Liu D, Tsuyama K, Maeda Y, Namai S, Kumagai R, Tracey A, Holroyd N, Doyle SR, Woodruff GC, Murase K, Kitazume H, Chai C, Akagi A, Panda O, Ke HM, Schroeder FC, Wang J, Berriman M, Sternberg PW, Sugimoto A, Kikuchi T.

Nat Commun. 2018 Aug 10;9(1):3216. doi: 10.1038/s41467-018-05712-5.


Using Transcriptomes as Mutant Phenotypes Reveals Functional Regions of a Mediator Subunit in Caenorhabditis elegans.

Angeles-Albores D, Sternberg PW.

Genetics. 2018 Sep;210(1):15-24. doi: 10.1534/genetics.118.301133. Epub 2018 Jul 20.


Micropublication: incentivizing community curation and placing unpublished data into the public domain.

Raciti D, Yook K, Harris TW, Schedl T, Sternberg PW.

Database (Oxford). 2018 Jan 1;2018. doi: 10.1093/database/bay013.


Avoid Compromises in the Current Opioid Crisis, Using Cautious but Confident Patient Care-Reply.

Patel S, Sternberg P Jr.

JAMA Ophthalmol. 2018 May 1;136(5):595-596. doi: 10.1001/jamaophthalmol.2018.0636. No abstract available.


Split cGAL, an intersectional strategy using a split intein for refined spatiotemporal transgene control in Caenorhabditis elegans.

Wang H, Liu J, Yuet KP, Hill AJ, Sternberg PW.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3900-3905. doi: 10.1073/pnas.1720063115. Epub 2018 Mar 26.


Reconstructing a metazoan genetic pathway with transcriptome-wide epistasis measurements.

Angeles-Albores D, Puckett Robinson C, Williams BA, Wold BJ, Sternberg PW.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2930-E2939. doi: 10.1073/pnas.1712387115. Epub 2018 Mar 12.


Textpresso Central: a customizable platform for searching, text mining, viewing, and curating biomedical literature.

Müller HM, Van Auken KM, Li Y, Sternberg PW.

BMC Bioinformatics. 2018 Mar 9;19(1):94. doi: 10.1186/s12859-018-2103-8.


Metabolomic "Dark Matter" Dependent on Peroxisomal β-Oxidation in Caenorhabditis elegans.

Artyukhin AB, Zhang YK, Akagi AE, Panda O, Sternberg PW, Schroeder FC.

J Am Chem Soc. 2018 Feb 28;140(8):2841-2852. doi: 10.1021/jacs.7b11811. Epub 2018 Feb 16.


A Toolkit of Engineered Recombinational Balancers in C. elegans.

Schwartz HT, Sternberg PW.

Trends Genet. 2018 Apr;34(4):253-255. doi: 10.1016/j.tig.2018.01.009. Epub 2018 Jan 31.


Non-neuronal cell outgrowth in C. elegans.

Ghosh S, Vetrone SA, Sternberg PW.

Worm. 2017 Nov 14;6(3-4):e1405212. doi: 10.1080/21624054.2017.1405212. eCollection 2017. Review.


Association Between Ophthalmologist Age and Unsolicited Patient Complaints.

Fathy CA, Pichert JW, Domenico H, Kohanim S, Sternberg P, Cooper WO.

JAMA Ophthalmol. 2018 Jan 1;136(1):61-67. doi: 10.1001/jamaophthalmol.2017.5154.


FMRFamide-like peptides expand the behavioral repertoire of a densely connected nervous system.

Lee JS, Shih PY, Schaedel ON, Quintero-Cadena P, Rogers AK, Sternberg PW.

Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10726-E10735. doi: 10.1073/pnas.1710374114. Epub 2017 Nov 22.


Presence of Trainees and Appointment Times.

Lindsey JL, Sternberg P Jr.

JAMA Ophthalmol. 2018 Jan 1;136(1):27-28. doi: 10.1001/jamaophthalmol.2017.4785. No abstract available.


Evolving Concepts in the Management of Retinopathy of Prematurity.

Sternberg P Jr, Durrani AK.

Am J Ophthalmol. 2018 Feb;186:xxiii-xxxii. doi: 10.1016/j.ajo.2017.10.027. Epub 2017 Nov 3.


Genome-wide discovery of active regulatory elements and transcription factor footprints in Caenorhabditis elegans using DNase-seq.

Ho MCW, Quintero-Cadena P, Sternberg PW.

Genome Res. 2017 Dec;27(12):2108-2119. doi: 10.1101/gr.223735.117. Epub 2017 Oct 26.


WormBase 2017: molting into a new stage.

Lee RYN, Howe KL, Harris TW, Arnaboldi V, Cain S, Chan J, Chen WJ, Davis P, Gao S, Grove C, Kishore R, Muller HM, Nakamura C, Nuin P, Paulini M, Raciti D, Rodgers F, Russell M, Schindelman G, Tuli MA, Van Auken K, Wang Q, Williams G, Wright A, Yook K, Berriman M, Kersey P, Schedl T, Stein L, Sternberg PW.

Nucleic Acids Res. 2018 Jan 4;46(D1):D869-D874. doi: 10.1093/nar/gkx998.


Association Between Opioid Prescribing Patterns and Abuse in Ophthalmology.

Patel S, Sternberg P Jr.

JAMA Ophthalmol. 2017 Nov 1;135(11):1216-1220. doi: 10.1001/jamaophthalmol.2017.4055.


The Jellyfish Cassiopea Exhibits a Sleep-like State.

Nath RD, Bedbrook CN, Abrams MJ, Basinger T, Bois JS, Prober DA, Sternberg PW, Gradinaru V, Goentoro L.

Curr Biol. 2017 Oct 9;27(19):2984-2990.e3. doi: 10.1016/j.cub.2017.08.014. Epub 2017 Sep 21.


The Solar Eclipse of 2017-A (Protected) View From the Path of Totality.

Calkins DJ, Sternberg P.

JAMA Ophthalmol. 2017 Sep 1;135(9):907-908. doi: 10.1001/jamaophthalmol.2017.2936. No abstract available.


The Caenorhabditis elegans Female-Like State: Decoupling the Transcriptomic Effects of Aging and Sperm Status.

Angeles-Albores D, Leighton DHW, Tsou T, Khaw TH, Antoshechkin I, Sternberg PW.

G3 (Bethesda). 2017 Sep 7;7(9):2969-2977. doi: 10.1534/g3.117.300080.


Automated Analysis of a Nematode Population-based Chemosensory Preference Assay.

Chai CM, Cronin CJ, Sternberg PW.

J Vis Exp. 2017 Jul 13;(125). doi: 10.3791/55963.


Clinical Presentation of Acute Gastroenteritis in Children With Functional Abdominal Pain Disorders.

Saps M, Mintjens S, Pusatcioglu CK, Cohen DM, Sternberg P.

J Pediatr Gastroenterol Nutr. 2017 Aug;65(2):165-167. doi: 10.1097/MPG.0000000000001466.


Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.

Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB.

FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7.


Whipworm kinomes reflect a unique biology and adaptation to the host animal.

Stroehlein AJ, Young ND, Korhonen PK, Chang BCH, Nejsum P, Pozio E, La Rosa G, Sternberg PW, Gasser RB.

Int J Parasitol. 2017 Nov;47(13):857-866. doi: 10.1016/j.ijpara.2017.04.005. Epub 2017 Jun 10.


Improved Synthesis for Modular Ascarosides Uncovers Biological Activity.

Zhang YK, Sanchez-Ayala MA, Sternberg PW, Srinivasan J, Schroeder FC.

Org Lett. 2017 Jun 2;19(11):2837-2840. doi: 10.1021/acs.orglett.7b01009. Epub 2017 May 17.


Diabetic Retinopathy and Antivascular Endothelial Growth Factor Agents.

Patel S, Sternberg P Jr.

JAMA Ophthalmol. 2017 Jun 1;135(6):568-569. doi: 10.1001/jamaophthalmol.2017.0318. No abstract available.


Biosynthesis of Modular Ascarosides in C. elegans.

Panda O, Akagi AE, Artyukhin AB, Judkins JC, Le HH, Mahanti P, Cohen SM, Sternberg PW, Schroeder FC.

Angew Chem Int Ed Engl. 2017 Apr 18;56(17):4729-4733. doi: 10.1002/anie.201700103. Epub 2017 Mar 28.


In Retrospect: Forty years of cellular clues from worms.

Sternberg PW.

Nature. 2017 Mar 29;543(7647):628-630. doi: 10.1038/543628a. No abstract available.


Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey.

Hsueh YP, Gronquist MR, Schwarz EM, Nath RD, Lee CH, Gharib S, Schroeder FC, Sternberg PW.

Elife. 2017 Jan 18;6. pii: e20023. doi: 10.7554/eLife.20023.


cGAL, a temperature-robust GAL4-UAS system for Caenorhabditis elegans.

Wang H, Liu J, Gharib S, Chai CM, Schwarz EM, Pokala N, Sternberg PW.

Nat Methods. 2017 Feb;14(2):145-148. doi: 10.1038/nmeth.4109. Epub 2016 Dec 19.


Enhancer Sharing Promotes Neighborhoods of Transcriptional Regulation Across Eukaryotes.

Quintero-Cadena P, Sternberg PW.

G3 (Bethesda). 2016 Dec 7;6(12):4167-4174. doi: 10.1534/g3.116.036228.


Mapping a multiplexed zoo of mRNA expression.

Choi HM, Calvert CR, Husain N, Huss D, Barsi JC, Deverman BE, Hunter RC, Kato M, Lee SM, Abelin AC, Rosenthal AZ, Akbari OS, Li Y, Hay BA, Sternberg PW, Patterson PH, Davidson EH, Mazmanian SK, Prober DA, van de Rijn M, Leadbetter JR, Newman DK, Readhead C, Bronner ME, Wold B, Lansford R, Sauka-Spengler T, Fraser SE, Pierce NA.

Development. 2016 Oct 1;143(19):3632-3637.


The tubulin repertoire of C. elegans sensory neurons and its context-dependent role in process outgrowth.

Lockhead D, Schwarz EM, O'Hagan R, Bellotti S, Krieg M, Barr MM, Dunn AR, Sternberg PW, Goodman MB.

Mol Biol Cell. 2016 Sep 21. pii: mbc.E16-06-0473. [Epub ahead of print]


Tissue enrichment analysis for C. elegans genomics.

Angeles-Albores D, N Lee RY, Chan J, Sternberg PW.

BMC Bioinformatics. 2016 Sep 13;17(1):366. doi: 10.1186/s12859-016-1229-9.


C. elegans Stress-Induced Sleep Emerges from the Collective Action of Multiple Neuropeptides.

Nath RD, Chow ES, Wang H, Schwarz EM, Sternberg PW.

Curr Biol. 2016 Sep 26;26(18):2446-2455. doi: 10.1016/j.cub.2016.07.048. Epub 2016 Aug 18.


Analyses of Compact Trichinella Kinomes Reveal a MOS-Like Protein Kinase with a Unique N-Terminal Domain.

Stroehlein AJ, Young ND, Korhonen PK, Chang BC, Sternberg PW, La Rosa G, Pozio E, Gasser RB.

G3 (Bethesda). 2016 Sep 8;6(9):2847-56. doi: 10.1534/g3.116.032961.


CAP protein superfamily members in Toxocara canis.

Stroehlein AJ, Young ND, Hall RS, Korhonen PK, Hofmann A, Sternberg PW, Jabbar A, Gasser RB.

Parasit Vectors. 2016 Jun 24;9(1):360. doi: 10.1186/s13071-016-1642-y.


Anchor cell signaling and vulval precursor cell positioning establish a reproducible spatial context during C. elegans vulval induction.

Grimbert S, Tietze K, Barkoulas M, Sternberg PW, Félix MA, Braendle C.

Dev Biol. 2016 Aug 1;416(1):123-135. doi: 10.1016/j.ydbio.2016.05.036. Epub 2016 Jun 8.


Mating pheromones of Nematoda: olfactory signaling with physiological consequences.

Leighton DH, Sternberg PW.

Curr Opin Neurobiol. 2016 Jun;38:119-24. doi: 10.1016/j.conb.2016.04.008. Epub 2016 May 21. Review.


Disparities in Adherence to Screening Guidelines for Diabetic Retinopathy in the United States: A Comprehensive Review and Guide for Future Directions.

Fathy C, Patel S, Sternberg P Jr, Kohanim S.

Semin Ophthalmol. 2016;31(4):364-77. doi: 10.3109/08820538.2016.1154170. Epub 2016 Apr 26. Review.


Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans.

Narayan A, Venkatachalam V, Durak O, Reilly DK, Bose N, Schroeder FC, Samuel AD, Srinivasan J, Sternberg PW.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):E1392-401. doi: 10.1073/pnas.1600786113. Epub 2016 Feb 22.


Routine Use of Nonsteroidal Anti-inflammatory Drugs with Corticosteroids in Cataract Surgery: Beneficial or Redundant?

Kim SJ, Patel SN, Sternberg P Jr.

Ophthalmology. 2016 Mar;123(3):444-6. doi: 10.1016/j.ophtha.2015.10.042. No abstract available.


Muscle Logic: New Knowledge Resource for Anatomy Enables Comprehensive Searches of the Literature on the Feeding Muscles of Mammals.

Druzinsky RE, Balhoff JP, Crompton AW, Done J, German RZ, Haendel MA, Herrel A, Herring SW, Lapp H, Mabee PM, Muller HM, Mungall CJ, Sternberg PW, Van Auken K, Vinyard CJ, Williams SH, Wall CE.

PLoS One. 2016 Feb 12;11(2):e0149102. doi: 10.1371/journal.pone.0149102. eCollection 2016.


Dictyocaulus viviparus genome, variome and transcriptome elucidate lungworm biology and support future intervention.

McNulty SN, Strübe C, Rosa BA, Martin JC, Tyagi R, Choi YJ, Wang Q, Hallsworth Pepin K, Zhang X, Ozersky P, Wilson RK, Sternberg PW, Gasser RB, Mitreva M.

Sci Rep. 2016 Feb 9;6:20316. doi: 10.1038/srep20316.


Reconstruction of the insulin-like signalling pathway of Haemonchus contortus.

Mohandas N, Hu M, Stroehlein AJ, Young ND, Sternberg PW, Lok JB, Gasser RB.

Parasit Vectors. 2016 Feb 3;9:64. doi: 10.1186/s13071-016-1341-8.


Phylogenomic and biogeographic reconstruction of the Trichinella complex.

Korhonen PK, Pozio E, La Rosa G, Chang BC, Koehler AV, Hoberg EP, Boag PR, Tan P, Jex AR, Hofmann A, Sternberg PW, Young ND, Gasser RB.

Nat Commun. 2016 Feb 1;7:10513. doi: 10.1038/ncomms10513.


The Haemonchus contortus kinome--a resource for fundamental molecular investigations and drug discovery.

Stroehlein AJ, Young ND, Korhonen PK, Jabbar A, Hofmann A, Sternberg PW, Gasser RB.

Parasit Vectors. 2015 Dec 8;8:623. doi: 10.1186/s13071-015-1231-5.


Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets.

Stroehlein AJ, Young ND, Jex AR, Sternberg PW, Tan P, Boag PR, Hofmann A, Gasser RB.

Sci Rep. 2015 Dec 4;5:17759. doi: 10.1038/srep17759.

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