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Items: 45

1.

Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2.

Malakar P, Stein I, Saragovi A, Winkler R, Stern-Ginossar N, Berger M, Pikarsky E, Karni R.

Cancer Res. 2019 May 15;79(10):2480-2493. doi: 10.1158/0008-5472.CAN-18-1432. Epub 2019 Mar 26.

PMID:
30914432
2.

The Transcriptome of Latent Human Cytomegalovirus.

Schwartz M, Stern-Ginossar N.

J Virol. 2019 May 15;93(11). pii: e00047-19. doi: 10.1128/JVI.00047-19. Print 2019 Jun 1. Review.

PMID:
30867313
3.

Publisher Correction: m6A modification controls the innate immune response to infection by targeting type I interferons.

Winkler R, Gillis E, Lasman L, Safra M, Geula S, Soyris C, Nachshon A, Tai-Schmiedel J, Friedman N, Le-Trilling VTK, Trilling M, Mandelboim M, Hanna JH, Schwartz S, Stern-Ginossar N.

Nat Immunol. 2019 Feb;20(2):243. doi: 10.1038/s41590-019-0314-4.

PMID:
30635652
4.

m6A modification controls the innate immune response to infection by targeting type I interferons.

Winkler R, Gillis E, Lasman L, Safra M, Geula S, Soyris C, Nachshon A, Tai-Schmiedel J, Friedman N, Le-Trilling VTK, Trilling M, Mandelboim M, Hanna JH, Schwartz S, Stern-Ginossar N.

Nat Immunol. 2019 Feb;20(2):173-182. doi: 10.1038/s41590-018-0275-z. Epub 2018 Dec 17. Erratum in: Nat Immunol. 2019 Jan 11;:.

PMID:
30559377
5.

Virus-Induced Changes in mRNA Secondary Structure Uncover cis-Regulatory Elements that Directly Control Gene Expression.

Mizrahi O, Nachshon A, Shitrit A, Gelbart IA, Dobesova M, Brenner S, Kahana C, Stern-Ginossar N.

Mol Cell. 2018 Dec 6;72(5):862-874.e5. doi: 10.1016/j.molcel.2018.09.003. Epub 2018 Oct 11.

PMID:
30318442
6.

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.

Lee JS, Adler L, Karathia H, Carmel N, Rabinovich S, Auslander N, Keshet R, Stettner N, Silberman A, Agemy L, Helbling D, Eilam R, Sun Q, Brandis A, Malitsky S, Itkin M, Weiss H, Pinto S, Kalaora S, Levy R, Barnea E, Admon A, Dimmock D, Stern-Ginossar N, Scherz A, Nagamani SCS, Unda M, Wilson DM 3rd, Elhasid R, Carracedo A, Samuels Y, Hannenhalli S, Ruppin E, Erez A.

Cell. 2018 Sep 6;174(6):1559-1570.e22. doi: 10.1016/j.cell.2018.07.019. Epub 2018 Aug 9.

PMID:
30100185
7.

Translational Control in Virus-Infected Cells.

Stern-Ginossar N, Thompson SR, Mathews MB, Mohr I.

Cold Spring Harb Perspect Biol. 2019 Mar 1;11(3). pii: a033001. doi: 10.1101/cshperspect.a033001. Review.

PMID:
29891561
8.

Decay of the Stress-Induced Ligand MICA Is Controlled by the Expression of an Alternative 3' Untranslated Region.

Toledano T, Vitenshtein A, Stern-Ginossar N, Seidel E, Mandelboim O.

J Immunol. 2018 Apr 15;200(8):2819-2825. doi: 10.4049/jimmunol.1700968. Epub 2018 Mar 14.

9.

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing.

Shnayder M, Nachshon A, Krishna B, Poole E, Boshkov A, Binyamin A, Maza I, Sinclair J, Schwartz M, Stern-Ginossar N.

MBio. 2018 Mar 13;9(2). pii: e00013-18. doi: 10.1128/mBio.00013-18.

10.

Translational control of ERK signaling through miRNA/4EHP-directed silencing.

Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas CG, Stern-Ginossar N, Tuschl T, Gingras AC, Duchaine TF, Sonenberg N.

Elife. 2018 Feb 7;7. pii: e35034. doi: 10.7554/eLife.35034.

11.

Viral Short ORFs and Their Possible Functions.

Finkel Y, Stern-Ginossar N, Schwartz M.

Proteomics. 2018 May;18(10):e1700255. doi: 10.1002/pmic.201700255. Epub 2018 Jan 19. Review.

PMID:
29150926
12.

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.

Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G.

Nat Commun. 2017 Nov 13;8(1):1440. doi: 10.1038/s41467-017-01458-8.

13.

The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution.

Safra M, Sas-Chen A, Nir R, Winkler R, Nachshon A, Bar-Yaacov D, Erlacher M, Rossmanith W, Stern-Ginossar N, Schwartz S.

Nature. 2017 Nov 9;551(7679):251-255. doi: 10.1038/nature24456. Epub 2017 Oct 25.

PMID:
29072297
14.

Global mRNA polarization regulates translation efficiency in the intestinal epithelium.

Moor AE, Golan M, Massasa EE, Lemze D, Weizman T, Shenhav R, Baydatch S, Mizrahi O, Winkler R, Golani O, Stern-Ginossar N, Itzkovitz S.

Science. 2017 Sep 22;357(6357):1299-1303. doi: 10.1126/science.aan2399. Epub 2017 Aug 10.

15.

Cap-binding protein 4EHP effects translation silencing by microRNAs.

Chapat C, Jafarnejad SM, Matta-Camacho E, Hesketh GG, Gelbart IA, Attig J, Gkogkas CG, Alain T, Stern-Ginossar N, Fabian MR, Gingras AC, Duchaine TF, Sonenberg N.

Proc Natl Acad Sci U S A. 2017 May 23;114(21):5425-5430. doi: 10.1073/pnas.1701488114. Epub 2017 May 9.

16.

A systematic view on influenza induced host shutoff.

Bercovich-Kinori A, Tai J, Gelbart IA, Shitrit A, Ben-Moshe S, Drori Y, Itzkovitz S, Mandelboim M, Stern-Ginossar N.

Elife. 2016 Aug 15;5. pii: e18311. doi: 10.7554/eLife.18311.

17.

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells.

Tichon A, Gil N, Lubelsky Y, Havkin Solomon T, Lemze D, Itzkovitz S, Stern-Ginossar N, Ulitsky I.

Nat Commun. 2016 Jul 13;7:12209. doi: 10.1038/ncomms12209.

18.

CEACAM1-Mediated Inhibition of Virus Production.

Vitenshtein A, Weisblum Y, Hauka S, Halenius A, Oiknine-Djian E, Tsukerman P, Bauman Y, Bar-On Y, Stern-Ginossar N, Enk J, Ortenberg R, Tai J, Markel G, Blumberg RS, Hengel H, Jonjic S, Wolf DG, Adler H, Kammerer R, Mandelboim O.

Cell Rep. 2016 Jun 14;15(11):2331-9. doi: 10.1016/j.celrep.2016.05.036. Epub 2016 Jun 2.

19.

Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria.

Dar D, Shamir M, Mellin JR, Koutero M, Stern-Ginossar N, Cossart P, Sorek R.

Science. 2016 Apr 8;352(6282):aad9822. doi: 10.1126/science.aad9822.

20.

Ribosome Profiling as a Tool to Decipher Viral Complexity.

Stern-Ginossar N, Ingolia NT.

Annu Rev Virol. 2015 Nov;2(1):335-49. doi: 10.1146/annurev-virology-100114-054854. Epub 2015 Jul 30. Review.

PMID:
26958919
21.

Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes.

Weingarten-Gabbay S, Elias-Kirma S, Nir R, Gritsenko AA, Stern-Ginossar N, Yakhini Z, Weinberger A, Segal E.

Science. 2016 Jan 15;351(6270). pii: aad4939. doi: 10.1126/science.aad4939. Epub 2016 Jan 14.

22.

A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation.

Fields AP, Rodriguez EH, Jovanovic M, Stern-Ginossar N, Haas BJ, Mertins P, Raychowdhury R, Hacohen N, Carr SA, Ingolia NT, Regev A, Weissman JS.

Mol Cell. 2015 Dec 3;60(5):816-827. doi: 10.1016/j.molcel.2015.11.013.

23.

The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.

Tirosh O, Cohen Y, Shitrit A, Shani O, Le-Trilling VT, Trilling M, Friedlander G, Tanenbaum M, Stern-Ginossar N.

PLoS Pathog. 2015 Nov 24;11(11):e1005288. doi: 10.1371/journal.ppat.1005288. eCollection 2015.

24.

Regulation of mRNA translation during mitosis.

Tanenbaum ME, Stern-Ginossar N, Weissman JS, Vale RD.

Elife. 2015 Aug 25;4. doi: 10.7554/eLife.07957.

25.

Decoding viral infection by ribosome profiling.

Stern-Ginossar N.

J Virol. 2015 Jun;89(12):6164-6. doi: 10.1128/JVI.02528-14. Epub 2015 Mar 25. Review.

26.

Stem cells. m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation.

Geula S, Moshitch-Moshkovitz S, Dominissini D, Mansour AA, Kol N, Salmon-Divon M, Hershkovitz V, Peer E, Mor N, Manor YS, Ben-Haim MS, Eyal E, Yunger S, Pinto Y, Jaitin DA, Viukov S, Rais Y, Krupalnik V, Chomsky E, Zerbib M, Maza I, Rechavi Y, Massarwa R, Hanna S, Amit I, Levanon EY, Amariglio N, Stern-Ginossar N, Novershtern N, Rechavi G, Hanna JH.

Science. 2015 Feb 27;347(6225):1002-6. doi: 10.1126/science.1261417. Epub 2015 Jan 1.

27.

Manipulation of host pathways by human cytomegalovirus: insights from genome-wide studies.

Cohen Y, Stern-Ginossar N.

Semin Immunopathol. 2014 Nov;36(6):651-8. doi: 10.1007/s00281-014-0443-7. Epub 2014 Sep 27. Review.

PMID:
25260940
28.

Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes.

Ingolia NT, Brar GA, Stern-Ginossar N, Harris MS, Talhouarne GJ, Jackson SE, Wills MR, Weissman JS.

Cell Rep. 2014 Sep 11;8(5):1365-79. doi: 10.1016/j.celrep.2014.07.045. Epub 2014 Aug 21.

29.

Expansion of CD16 positive and negative human NK cells in response to tumor stimulation.

Tsukerman P, Stern-Ginossar N, Yamin R, Ophir Y, Stanietsky AM, Mandelboim O.

Eur J Immunol. 2014 May;44(5):1517-25. doi: 10.1002/eji.201344170. Epub 2014 Feb 20.

30.

KSHV 2.0: a comprehensive annotation of the Kaposi's sarcoma-associated herpesvirus genome using next-generation sequencing reveals novel genomic and functional features.

Arias C, Weisburd B, Stern-Ginossar N, Mercier A, Madrid AS, Bellare P, Holdorf M, Weissman JS, Ganem D.

PLoS Pathog. 2014 Jan;10(1):e1003847. doi: 10.1371/journal.ppat.1003847. Epub 2014 Jan 16.

31.

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS.

Cell. 2013 Jul 18;154(2):442-51. doi: 10.1016/j.cell.2013.06.044. Epub 2013 Jul 11.

32.

Decoding human cytomegalovirus.

Stern-Ginossar N, Weisburd B, Michalski A, Le VT, Hein MY, Huang SX, Ma M, Shen B, Qian SB, Hengel H, Mann M, Ingolia NT, Weissman JS.

Science. 2012 Nov 23;338(6110):1088-93. doi: 10.1126/science.1227919.

33.

MiR-10b downregulates the stress-induced cell surface molecule MICB, a critical ligand for cancer cell recognition by natural killer cells.

Tsukerman P, Stern-Ginossar N, Gur C, Glasner A, Nachmani D, Bauman Y, Yamin R, Vitenshtein A, Stanietsky N, Bar-Mag T, Lankry D, Mandelboim O.

Cancer Res. 2012 Nov 1;72(21):5463-72. doi: 10.1158/0008-5472.CAN-11-2671. Epub 2012 Aug 21.

34.

An identical miRNA of the human JC and BK polyoma viruses targets the stress-induced ligand ULBP3 to escape immune elimination.

Bauman Y, Nachmani D, Vitenshtein A, Tsukerman P, Drayman N, Stern-Ginossar N, Lankry D, Gruda R, Mandelboim O.

Cell Host Microbe. 2011 Feb 17;9(2):93-102. doi: 10.1016/j.chom.2011.01.008.

35.

The activating receptor NKp46 is essential for the development of type 1 diabetes.

Gur C, Porgador A, Elboim M, Gazit R, Mizrahi S, Stern-Ginossar N, Achdout H, Ghadially H, Dor Y, Nir T, Doviner V, Hershkovitz O, Mendelson M, Naparstek Y, Mandelboim O.

Nat Immunol. 2010 Feb;11(2):121-8. doi: 10.1038/ni.1834. Epub 2009 Dec 20.

PMID:
20023661
36.

Notch activation enhances IFNgamma secretion by human peripheral blood and decidual NK cells.

Manaster I, Gazit R, Goldman-Wohl D, Stern-Ginossar N, Mizrahi S, Yagel S, Mandelboim O.

J Reprod Immunol. 2010 Jan;84(1):1-7. doi: 10.1016/j.jri.2009.10.009. Epub 2009 Dec 11.

PMID:
20004979
37.

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity.

Stanietsky N, Simic H, Arapovic J, Toporik A, Levy O, Novik A, Levine Z, Beiman M, Dassa L, Achdout H, Stern-Ginossar N, Tsukerman P, Jonjic S, Mandelboim O.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17858-63. doi: 10.1073/pnas.0903474106. Epub 2009 Oct 7.

38.

An integrated view of the regulation of NKG2D ligands.

Stern-Ginossar N, Mandelboim O.

Immunology. 2009 Sep;128(1):1-6. doi: 10.1111/j.1365-2567.2009.03147.x. Review.

39.

Analysis of human cytomegalovirus-encoded microRNA activity during infection.

Stern-Ginossar N, Saleh N, Goldberg MD, Prichard M, Wolf DG, Mandelboim O.

J Virol. 2009 Oct;83(20):10684-93. doi: 10.1128/JVI.01292-09. Epub 2009 Aug 5.

40.

Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells.

Nachmani D, Stern-Ginossar N, Sarid R, Mandelboim O.

Cell Host Microbe. 2009 Apr 23;5(4):376-85. doi: 10.1016/j.chom.2009.03.003.

41.

Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D.

Stern-Ginossar N, Gur C, Biton M, Horwitz E, Elboim M, Stanietsky N, Mandelboim M, Mandelboim O.

Nat Immunol. 2008 Sep;9(9):1065-73. doi: 10.1038/ni.1642.

PMID:
18677316
42.

Endometrial NK cells are special immature cells that await pregnancy.

Manaster I, Mizrahi S, Goldman-Wohl D, Sela HY, Stern-Ginossar N, Lankry D, Gruda R, Hurwitz A, Bdolah Y, Haimov-Kochman R, Yagel S, Mandelboim O.

J Immunol. 2008 Aug 1;181(3):1869-76.

43.

Intercellular transfer of carcinoembryonic antigen from tumor cells to NK cells.

Stern-Ginossar N, Nedvetzki S, Markel G, Gazit R, Betser-Cohen G, Achdout H, Aker M, Blumberg RS, Davis DM, Appelmelk B, Mandelboim O.

J Immunol. 2007 Oct 1;179(7):4424-34.

44.

Intracellular cysteine residues in the tail of MHC class I proteins are crucial for extracellular recognition by leukocyte Ig-like receptor 1.

Gruda R, Achdout H, Stern-Ginossar N, Gazit R, Betser-Cohen G, Manaster I, Katz G, Gonen-Gross T, Tirosh B, Mandelboim O.

J Immunol. 2007 Sep 15;179(6):3655-61.

45.

Host immune system gene targeting by a viral miRNA.

Stern-Ginossar N, Elefant N, Zimmermann A, Wolf DG, Saleh N, Biton M, Horwitz E, Prokocimer Z, Prichard M, Hahn G, Goldman-Wohl D, Greenfield C, Yagel S, Hengel H, Altuvia Y, Margalit H, Mandelboim O.

Science. 2007 Jul 20;317(5836):376-81.

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