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Duvelisib, an oral dual PI3K-δ,γ inhibitor, shows clinical and pharmacodynamic activity in chronic lymphocytic leukemia and small lymphocytic lymphoma in a Phase 1 study.

O'Brien S, Patel M, Kahl BS, Horwitz SM, Foss FM, Porcu P, Jones J, Burger J, Jain N, Allen K, Faia K, Douglas M, Stern HM, Sweeney J, Kelly P, Kelly V, Flinn I.

Am J Hematol. 2018 Aug 10. doi: 10.1002/ajh.25243. [Epub ahead of print]


Duvelisib, an oral dual PI3K-δ, γ inhibitor, shows clinical activity in indolent non-Hodgkin lymphoma in a phase 1 study.

Flinn IW, Patel M, Oki Y, Horwitz S, Foss FF, Allen K, Douglas M, Stern H, Sweeney J, Kharidia J, Kelly P, Kelly VM, Kahl B.

Am J Hematol. 2018 Jul 22. doi: 10.1002/ajh.25228. [Epub ahead of print]


Characterization of Nine Cancer-Associated Variants in Human DNA Polymerase κ.

Antczak NM, Walker AR, Stern HR, Leddin EM, Palad C, Coulther TA, Swett RJ, Cisneros GA, Beuning PJ.

Chem Res Toxicol. 2018 Aug 20;31(8):697-711. doi: 10.1021/acs.chemrestox.8b00055. Epub 2018 Jul 30.


Vulnerability of Arctic marine mammals to vessel traffic in the increasingly ice-free Northwest Passage and Northern Sea Route.

Hauser DDW, Laidre KL, Stern HL.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7617-7622. doi: 10.1073/pnas.1803543115. Epub 2018 Jul 2.


Does Anhedonia Presage Increased Risk of Posttraumatic Stress Disorder? : Adolescent Anhedonia and Posttraumatic Disorders.

Risbrough VB, Glynn LM, Davis EP, Sandman CA, Obenaus A, Stern HS, Keator DB, Yassa MA, Baram TZ, Baker DG.

Curr Top Behav Neurosci. 2018;38:249-265. doi: 10.1007/7854_2018_51.


Wall shear stress estimation in the aorta: Impact of wall motion, spatiotemporal resolution, and phase noise.

Zimmermann J, Demedts D, Mirzaee H, Ewert P, Stern H, Meierhofer C, Menze B, Hennemuth A.

J Magn Reson Imaging. 2018 Apr 1. doi: 10.1002/jmri.26007. [Epub ahead of print]


Diffuse fibrosis is common in the left, but not in the right ventricle in patients with transposition of the great arteries late after atrial switch operation.

Shehu N, Meierhofer C, Messroghli D, Mkrtchyan N, Martinoff S, Ewert P, Stern H.

Int J Cardiovasc Imaging. 2018 Aug;34(8):1241-1248. doi: 10.1007/s10554-018-1338-9. Epub 2018 Mar 29.


Data and methods for studying commercial motor vehicle driver fatigue, highway safety and long-term driver health.

Stern HS, Blower D, Cohen ML, Czeisler CA, Dinges DF, Greenhouse JB, Guo F, Hanowski RJ, Hartenbaum NP, Krueger GP, Mallis MM, Pain RF, Rizzo M, Sinha E, Small DS, Stuart EA, Wegman DH.

Accid Anal Prev. 2018 Mar 9. pii: S0001-4575(18)30083-6. doi: 10.1016/j.aap.2018.02.021. [Epub ahead of print]


Antigenic cartography of H1N1 influenza viruses using sequence-based antigenic distance calculation.

Anderson CS, McCall PR, Stern HA, Yang H, Topham DJ.

BMC Bioinformatics. 2018 Feb 12;19(1):51. doi: 10.1186/s12859-018-2042-4.


Elucidation of Excitation Energy Dependent Correlated Triplet Pair Formation Pathways in an Endothermic Singlet Fission System.

Thampi A, Stern HL, Cheminal A, Tayebjee MJY, Petty AJ 2nd, Anthony JE, Rao A.

J Am Chem Soc. 2018 Apr 4;140(13):4613-4622. doi: 10.1021/jacs.7b06274. Epub 2018 Jan 9.


Prenatal maternal mood patterns predict child temperament and adolescent mental health.

Glynn LM, Howland MA, Sandman CA, Davis EP, Phelan M, Baram TZ, Stern HS.

J Affect Disord. 2018 Mar 1;228:83-90. doi: 10.1016/j.jad.2017.11.065. Epub 2017 Nov 14.


Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma.

Horwitz SM, Koch R, Porcu P, Oki Y, Moskowitz A, Perez M, Myskowski P, Officer A, Jaffe JD, Morrow SN, Allen K, Douglas M, Stern H, Sweeney J, Kelly P, Kelly V, Aster JC, Weaver D, Foss FM, Weinstock DM.

Blood. 2018 Feb 22;131(8):888-898. doi: 10.1182/blood-2017-08-802470. Epub 2017 Dec 12.


Corrigendum to: 'Clinical long-term outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in infants' [Eur J Cardiothorac Surg 2018;53:538--44].

Schleihauf J, Cleuziou J, Pabst von Ohain J, Meierhofer C, Stern H, Shehu N, Mkrtchyan N, Kaltenecker E, Kühn A, Nagdyman N, Hager A, Seidel H, Lange R, Ewert P, Wolf CM.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):694. doi: 10.1093/ejcts/ezx441. No abstract available.


Vibronically coherent ultrafast triplet-pair formation and subsequent thermally activated dissociation control efficient endothermic singlet fission.

Stern HL, Cheminal A, Yost SR, Broch K, Bayliss SL, Chen K, Tabachnyk M, Thorley K, Greenham N, Hodgkiss JM, Anthony J, Head-Gordon M, Musser AJ, Rao A, Friend RH.

Nat Chem. 2017 Dec;9(12):1205-1212. doi: 10.1038/nchem.2856. Epub 2017 Sep 11.


Aortopulmonary collateral flow quantification by MR at rest and during continuous submaximal exercise in patients with total cavopulmonary connection.

Mkrtchyan N, Frank Y, Steinlechner E, Calavrezos L, Meierhofer C, Hager A, Martinoff S, Ewert P, Stern H.

J Magn Reson Imaging. 2018 Jun;47(6):1509-1516. doi: 10.1002/jmri.25889. Epub 2017 Nov 6.


Clinical long-term outcome of septal myectomy for obstructive hypertrophic cardiomyopathy in infants.

Schleihauf J, Cleuziou J, Pabst von Ohain J, Meierhofer C, Stern H, Shehu N, Mkrtchyan N, Kaltenecker E, Kühn A, Nagdyman N, Hager A, Seidel H, Lange R, Ewert P, Wolf CM.

Eur J Cardiothorac Surg. 2018 Mar 1;53(3):538-544. doi: 10.1093/ejcts/ezx369.


Harvesting wildlife affected by climate change: a modelling and management approach for polar bears.

Regehr EV, Wilson RR, Rode KD, Runge MC, Stern HL.

J Appl Ecol. 2017 Oct;54(5):1534-1543. doi: 10.1111/1365-2664.12864. Epub 2017 Mar 8.


Long-Standing Cyanosis in Congenital Heart Disease Does not Cause Diffuse Myocardial Fibrosis.

Kharabish A, Meierhofer C, Hadamitzky M, Nadjiri J, Martinoff S, Ewert P, Stern H.

Pediatr Cardiol. 2018 Jan;39(1):105-110. doi: 10.1007/s00246-017-1734-2. Epub 2017 Sep 25.


Exposure to unpredictable maternal sensory signals influences cognitive development across species.

Davis EP, Stout SA, Molet J, Vegetabile B, Glynn LM, Sandman CA, Heins K, Stern H, Baram TZ.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10390-10395. doi: 10.1073/pnas.1703444114. Epub 2017 Sep 11.


Forensic bitemark identification: weak foundations, exaggerated claims.

Saks MJ, Albright T, Bohan TL, Bierer BE, Bowers CM, Bush MA, Bush PJ, Casadevall A, Cole SA, Denton MB, Diamond SS, Dioso-Villa R, Epstein J, Faigman D, Faigman L, Fienberg SE, Garrett BL, Giannelli PC, Greely HT, Imwinkelried E, Jamieson A, Kafadar K, Kassirer JP, Koehler J', Korn D, Mnookin J, Morrison AB, Murphy E, Peerwani N, Peterson JL, Risinger DM, Sensabaugh GF, Spiegelman C, Stern H, Thompson WC, Wayman JL, Zabell S, Zumwalt RE.

J Law Biosci. 2016 Nov 23;3(3):538-575. doi: 10.1093/jlb/lsw045. eCollection 2016 Dec.


Importance of Non-invasive Right and Left Ventricular Variables on Exercise Capacity in Patients with Tetralogy of Fallot Hemodynamics.

Meierhofer C, Tavakkoli T, Kühn A, Ulm K, Hager A, Müller J, Martinoff S, Ewert P, Stern H.

Pediatr Cardiol. 2017 Dec;38(8):1569-1574. doi: 10.1007/s00246-017-1697-3. Epub 2017 Aug 3.


Synthesis and Exciton Dynamics of Donor-Orthogonal Acceptor Conjugated Polymers: Reducing the Singlet-Triplet Energy Gap.

Freeman DME, Musser AJ, Frost JM, Stern HL, Forster AK, Fallon KJ, Rapidis AG, Cacialli F, McCulloch I, Clarke TM, Friend RH, Bronstein H.

J Am Chem Soc. 2017 Aug 16;139(32):11073-11080. doi: 10.1021/jacs.7b03327. Epub 2017 Jun 23.


Risks of Stimulant Use for Attention Deficit Hyperactivity Disorder on the Developing Brain: Primum non nocere.

Stern HP, Lipman J, Andersen SL, Bossaer JB, Thigpen J.

Clin Pediatr (Phila). 2017 Aug;56(9):805-810. doi: 10.1177/0009922817706148. Epub 2017 May 1. No abstract available.


Evolution of right ventricular size over time after tetralogy of Fallot repair: a longitudinal cardiac magnetic resonance study.

Rutz T, Ghandour F, Meierhofer C, Naumann S, Martinoff S, Lange R, Ewert P, Stern HC, Fratz S.

Eur Heart J Cardiovasc Imaging. 2017 Mar 1;18(3):364-370. doi: 10.1093/ehjci/jew273.


Intraocular tuberculosis.

Pellerano F, Valdez E, Amador M, Leonor MN, Stern H.

Arch Soc Esp Oftalmol. 2017 Jul;92(7):e43. doi: 10.1016/j.oftal.2017.02.005. Epub 2017 Mar 24. English, Spanish. No abstract available.


Comparison of MR flow quantification in peripheral and main pulmonary arteries in patients after right ventricular outflow tract surgery: A retrospective study.

Rutz T, Meierhofer C, Naumann S, Martinoff S, Ewert P, Stern HC, Fratz S.

J Magn Reson Imaging. 2017 Dec;46(6):1839-1845. doi: 10.1002/jmri.25701. Epub 2017 Mar 16.


Habitat selection by two beluga whale populations in the Chukchi and Beaufort seas.

Hauser DD, Laidre KL, Stern HL, Moore SE, Suydam RS, Richard PR.

PLoS One. 2017 Feb 24;12(2):e0172755. doi: 10.1371/journal.pone.0172755. eCollection 2017.


Revised RNA Dihedral Parameters for the Amber Force Field Improve RNA Molecular Dynamics.

Aytenfisu AH, Spasic A, Grossfield A, Stern HA, Mathews DH.

J Chem Theory Comput. 2017 Feb 14;13(2):900-915. doi: 10.1021/acs.jctc.6b00870. Epub 2017 Jan 24.


Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199).

Patel VM, Balakrishnan K, Douglas M, Tibbitts T, Xu EY, Kutok JL, Ayers M, Sarkar A, Guerrieri R, Wierda WG, O'Brien S, Jain N, Stern HM, Gandhi V.

Leukemia. 2017 Sep;31(9):1872-1881. doi: 10.1038/leu.2016.382. Epub 2016 Dec 26.


Decadal shifts in autumn migration timing by Pacific Arctic beluga whales are related to delayed annual sea ice formation.

Hauser DDW, Laidre KL, Stafford KM, Stern HL, Suydam RS, Richard PR.

Glob Chang Biol. 2017 Jun;23(6):2206-2217. doi: 10.1111/gcb.13564. Epub 2016 Dec 21.


Choroidal metastasis from breast cancer.

Pellerano F, Fernández C, Soto H, Stern H.

Arch Soc Esp Oftalmol. 2017 Aug;92(8):e50. doi: 10.1016/j.oftal.2016.10.021. Epub 2016 Dec 8. English, Spanish. No abstract available.


Conservation status of polar bears (Ursus maritimus) in relation to projected sea-ice declines.

Regehr EV, Laidre KL, Akçakaya HR, Amstrup SC, Atwood TC, Lunn NJ, Obbard M, Stern H, Thiemann GW, Wiig Ø.

Biol Lett. 2016 Dec;12(12). pii: 20160556.


Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.

De Henau O, Rausch M, Winkler D, Campesato LF, Liu C, Cymerman DH, Budhu S, Ghosh A, Pink M, Tchaicha J, Douglas M, Tibbitts T, Sharma S, Proctor J, Kosmider N, White K, Stern H, Soglia J, Adams J, Palombella VJ, McGovern K, Kutok JL, Wolchok JD, Merghoub T.

Nature. 2016 Nov 17;539(7629):443-447. doi: 10.1038/nature20554. Epub 2016 Nov 9.


Limits for Recombination in a Low Energy Loss Organic Heterojunction.

Menke SM, Sadhanala A, Nikolka M, Ran NA, Ravva MK, Abdel-Azeim S, Stern HL, Wang M, Sirringhaus H, Nguyen TQ, Brédas JL, Bazan GC, Friend RH.

ACS Nano. 2016 Dec 27;10(12):10736-10744. doi: 10.1021/acsnano.6b06211. Epub 2016 Nov 3.


Cardiovascular magnetic resonance is successfully feasible in many patients aged 3 to 8years without general anesthesia or sedation.

Kharabish A, Mkrtchyan N, Meierhofer C, Martinoff S, Ewert P, Stern H, Fratz S.

J Clin Anesth. 2016 Nov;34:11-4. doi: 10.1016/j.jclinane.2016.02.048. Epub 2016 May 2.


Classic transcrural celiac plexus block simulated on 100 computed tomography images.

Yang IY, Oraee S, Viejo C, Stern H.

J Clin Anesth. 2016 May;30:35-41. doi: 10.1016/j.jclinane.2015.12.018. Epub 2016 Feb 20.


A Test by Any Other Name: P Values, Bayes Factors, and Statistical Inference.

Stern HS.

Multivariate Behav Res. 2016;51(1):23-9. doi: 10.1080/00273171.2015.1099032.


Cardiac Index During Routine Cardiovascular Magnetic Resonance in Young Children is Reduced Under General Anesthesia.

Mkrtchyan N, Stern H.

Pediatr Cardiol. 2016 Feb;37(2):426-7. doi: 10.1007/s00246-015-1324-0. Epub 2016 Jan 19. No abstract available.


Fragmentation and high entropy of neonatal experience predict adolescent emotional outcome.

Molet J, Heins K, Zhuo X, Mei YT, Regev L, Baram TZ, Stern H.

Transl Psychiatry. 2016 Jan 5;6:e702. doi: 10.1038/tp.2015.200.


The Function Biomedical Informatics Research Network Data Repository.

Keator DB, van Erp TG, Turner JA, Glover GH, Mueller BA, Liu TT, Voyvodic JT, Rasmussen J, Calhoun VD, Lee HJ, Toga AW, McEwen S, Ford JM, Mathalon DH, Diaz M, O'Leary DS, Jeremy Bockholt H, Gadde S, Preda A, Wible CG, Stern HS, Belger A, McCarthy G, Ozyurt B, Potkin SG; FBIRN.

Neuroimage. 2016 Jan 1;124(Pt B):1074-9. doi: 10.1016/j.neuroimage.2015.09.003. Epub 2015 Sep 11.


Glucagon Couples Hepatic Amino Acid Catabolism to mTOR-Dependent Regulation of α-Cell Mass.

Solloway MJ, Madjidi A, Gu C, Eastham-Anderson J, Clarke HJ, Kljavin N, Zavala-Solorio J, Kates L, Friedman B, Brauer M, Wang J, Fiehn O, Kolumam G, Stern H, Lowe JB, Peterson AS, Allan BB.

Cell Rep. 2015 Jul 21;12(3):495-510. doi: 10.1016/j.celrep.2015.06.034. Epub 2015 Jul 9.


Identification of a triplet pair intermediate in singlet exciton fission in solution.

Stern HL, Musser AJ, Gelinas S, Parkinson P, Herz LM, Bruzek MJ, Anthony J, Friend RH, Walker BJ.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7656-61. doi: 10.1073/pnas.1503471112. Epub 2015 Jun 9.


A tribute to Dr. Normand Belliveau.

Stern HS.

Can J Surg. 2015 Jun;58(3):153. No abstract available.


Normal values of right pulmonary to left pulmonary flow ratio in healthy individuals determined by cardiovascular magnetic resonance.

Fratz S, Meierhofer C, Martinoff S, Ewert P, Stern H, Rutz T.

Int J Cardiol. 2015 Jun 1;188:84-5. doi: 10.1016/j.ijcard.2015.04.027. Epub 2015 Apr 4. No abstract available.


Arctic marine mammal population status, sea ice habitat loss, and conservation recommendations for the 21st century.

Laidre KL, Stern H, Kovacs KM, Lowry L, Moore SE, Regehr EV, Ferguson SH, Wiig Ø, Boveng P, Angliss RP, Born EW, Litovka D, Quakenbush L, Lydersen C, Vongraven D, Ugarte F.

Conserv Biol. 2015 Jun;29(3):724-37. doi: 10.1111/cobi.12474. Epub 2015 Mar 17. Review.


Baseline correction does not improve flow quantification in phase-contrast velocity measurement for routine clinical practice.

Meierhofer C, Lyko C, Schneider EP, Stern H, Martinoff S, Hess J, Fratz S.

Clin Imaging. 2015 May-Jun;39(3):427-31. doi: 10.1016/j.clinimag.2014.12.010. Epub 2014 Dec 20.


PTEN Loss Is Associated with Worse Outcome in HER2-Amplified Breast Cancer Patients but Is Not Associated with Trastuzumab Resistance.

Stern HM, Gardner H, Burzykowski T, Elatre W, O'Brien C, Lackner MR, Pestano GA, Santiago A, Villalobos I, Eiermann W, Pienkowski T, Martin M, Robert N, Crown J, Nuciforo P, Bee V, Mackey J, Slamon DJ, Press MF.

Clin Cancer Res. 2015 May 1;21(9):2065-74. doi: 10.1158/1078-0432.CCR-14-2993. Epub 2015 Feb 3.


The first association of a primary amebic meningoencephalitis death with culturable Naegleria fowleri in tap water from a US treated public drinking water system.

Cope JR, Ratard RC, Hill VR, Sokol T, Causey JJ, Yoder JS, Mirani G, Mull B, Mukerjee KA, Narayanan J, Doucet M, Qvarnstrom Y, Poole CN, Akingbola OA, Ritter JM, Xiong Z, da Silva AJ, Roellig D, Van Dyke RB, Stern H, Xiao L, Beach MJ.

Clin Infect Dis. 2015 Apr 15;60(8):e36-42. doi: 10.1093/cid/civ017. Epub 2015 Jan 16.


HSP90 inhibition enhances antimitotic drug-induced mitotic arrest and cell death in preclinical models of non-small cell lung cancer.

O'Connell BC, O'Callaghan K, Tillotson B, Douglas M, Hafeez N, West KA, Stern H, Ali JA, Changelian P, Fritz CC, Palombella VJ, McGovern K, Kutok JL.

PLoS One. 2014 Dec 26;9(12):e115228. doi: 10.1371/journal.pone.0115228. eCollection 2014.


The effectiveness of flow cytometric sorting of human sperm (MicroSort®) for influencing a child's sex.

Karabinus DS, Marazzo DP, Stern HJ, Potter DA, Opanga CI, Cole ML, Johnson LA, Schulman JD.

Reprod Biol Endocrinol. 2014 Nov 24;12:106. doi: 10.1186/1477-7827-12-106.

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