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Items: 1 to 50 of 210

1.

Transplantation of hematopoietic stem cells: intra-arterial versus intravenous administration impacts stroke outcomes in a murine model.

Kasahara Y, Yamahara K, Soma T, Stern DM, Nakagomi T, Matsuyama T, Taguchi A.

Transl Res. 2016 Oct;176:69-80. doi: 10.1016/j.trsl.2016.04.003. Epub 2016 Apr 18.

PMID:
27164406
2.

Intravenous Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke: Phase1/2a Clinical Trial in a Homogeneous Group of Stroke Patients.

Taguchi A, Sakai C, Soma T, Kasahara Y, Stern DM, Kajimoto K, Ihara M, Daimon T, Yamahara K, Doi K, Kohara N, Nishimura H, Matsuyama T, Naritomi H, Sakai N, Nagatsuka K.

Stem Cells Dev. 2015 Oct 1;24(19):2207-18. doi: 10.1089/scd.2015.0160. Epub 2015 Aug 17.

3.

CD166/ALCAM mediates proinflammatory effects of S100B in delayed type hypersensitivity.

von Bauer R, Oikonomou D, Sulaj A, Mohammed S, Hotz-Wagenblatt A, Gröne HJ, Arnold B, Falk C, Luethje D, Erhardt A, Stern DM, Bierhaus A, Nawroth PP.

J Immunol. 2013 Jul 1;191(1):369-77. doi: 10.4049/jimmunol.1201864. Epub 2013 May 31.

4.

A highly reproducible model of cerebral ischemia/reperfusion with extended survival in CB-17 mice.

Kasahara Y, Ihara M, Nakagomi T, Momota Y, Stern DM, Matsuyama T, Taguchi A.

Neurosci Res. 2013 Jul;76(3):163-8. doi: 10.1016/j.neures.2013.04.001. Epub 2013 Apr 18.

PMID:
23603509
5.

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy.

Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasitschka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, Mier W, Pirags V, Lukic IK, Morcos M, Dehmer T, Rabbani N, Thornalley PJ, Edelstein D, Nau C, Forbes J, Humpert PM, Schwaninger M, Ziegler D, Stern DM, Cooper ME, Haberkorn U, Brownlee M, Reeh PW, Nawroth PP.

Nat Med. 2012 Jun;18(6):926-33. doi: 10.1038/nm.2750. Erratum in: Nat Med. 2012 Sep;18(9):1445. Lasischka, Felix [corrected to Lasitschka, Felix].

PMID:
22581285
6.

Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.

Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS.

J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011.

7.

A Reproducible and Simple Model of Permanent Cerebral Ischemia in CB-17 and SCID Mice.

Taguchi A, Kasahara Y, Nakagomi T, Stern DM, Fukunaga M, Ishikawa M, Matsuyama T.

J Exp Stroke Transl Med. 2010 Mar;3(1):28-33.

8.

Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats.

Taguchi A, Zhu P, Cao F, Kikuchi-Taura A, Kasahara Y, Stern DM, Soma T, Matsuyama T, Hata R.

J Cereb Blood Flow Metab. 2011 Mar;31(3):855-67. doi: 10.1038/jcbfm.2010.165. Epub 2010 Sep 22.

9.

Immunodeficiency reduces neural stem/progenitor cell apoptosis and enhances neurogenesis in the cerebral cortex after stroke.

Saino O, Taguchi A, Nakagomi T, Nakano-Doi A, Kashiwamura S, Doe N, Nakagomi N, Soma T, Yoshikawa H, Stern DM, Okamura H, Matsuyama T.

J Neurosci Res. 2010 Aug 15;88(11):2385-97. doi: 10.1002/jnr.22410.

PMID:
20623538
10.

Telmisartan suppresses cerebral injury in a murine model of transient focal ischemia.

Kasahara Y, Taguchi A, Uno H, Nakano A, Nakagomi T, Hirose H, Stern DM, Matsuyama T.

Brain Res. 2010 Jun 22;1340:70-80. doi: 10.1016/j.brainres.2010.03.101. Epub 2010 Apr 10.

PMID:
20388500
11.

Injury-induced neural stem/progenitor cells in post-stroke human cerebral cortex.

Nakayama D, Matsuyama T, Ishibashi-Ueda H, Nakagomi T, Kasahara Y, Hirose H, Kikuchi-Taura A, Stern DM, Mori H, Taguchi A.

Eur J Neurosci. 2010 Jan;31(1):90-8.

PMID:
20104652
12.

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.

Fang F, Lue LF, Yan S, Xu H, Luddy JS, Chen D, Walker DG, Stern DM, Yan S, Schmidt AM, Chen JX, Yan SS.

FASEB J. 2010 Apr;24(4):1043-55. doi: 10.1096/fj.09-139634. Epub 2009 Nov 11.

13.

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction.

Takuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H, Sosunov A, McKhann G, Funatsu Y, Nakamichi N, Nagai T, Mizoguchi H, Ibi D, Hori O, Ogawa S, Stern DM, Yamada K, Yan SS.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20021-6. doi: 10.1073/pnas.0905686106. Epub 2009 Nov 9.

14.

Differential effect of plasma or erythrocyte AGE-ligands of RAGE on expression of transcripts for receptor isoforms.

Grossin N, Wautier MP, Picot J, Stern DM, Wautier JL.

Diabetes Metab. 2009 Nov;35(5):410-7. doi: 10.1016/j.diabet.2009.04.009. Epub 2009 Oct 7.

PMID:
19815443
15.

Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.

Sliman SM, Eubank TD, Kotha SR, Kuppusamy ML, Sherwani SI, Butler ES, Kuppusamy P, Roy S, Marsh CB, Stern DM, Parinandi NL.

Mol Cell Biochem. 2010 Jan;333(1-2):9-26. doi: 10.1007/s11010-009-0199-x. Epub 2009 Jul 8.

16.

Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction.

Nakagomi N, Nakagomi T, Kubo S, Nakano-Doi A, Saino O, Takata M, Yoshikawa H, Stern DM, Matsuyama T, Taguchi A.

Stem Cells. 2009 Sep;27(9):2185-95. doi: 10.1002/stem.161.

17.

Anomaly in aortic arch alters pathological outcome of transient global ischemia in Rhesus macaques.

Hara K, Yasuhara T, Maki M, Matsukawa N, Yu G, Xu L, Tambrallo L, Rodriguez NA, Stern DM, Yamashima T, Buccafusco JJ, Kawase T, Hess DC, Borlongan CV.

Brain Res. 2009 Aug 25;1286:185-91. doi: 10.1016/j.brainres.2009.06.015. Epub 2009 Jun 12.

18.

Isolation and characterization of neural stem/progenitor cells from post-stroke cerebral cortex in mice.

Nakagomi T, Taguchi A, Fujimori Y, Saino O, Nakano-Doi A, Kubo S, Gotoh A, Soma T, Yoshikawa H, Nishizaki T, Nakagomi N, Stern DM, Matsuyama T.

Eur J Neurosci. 2009 May;29(9):1842-52. doi: 10.1111/j.1460-9568.2009.06732.x. Epub 2009 Apr 17.

PMID:
19473237
19.

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

Yan SD, Bierhaus A, Nawroth PP, Stern DM.

J Alzheimers Dis. 2009;16(4):833-43. doi: 10.3233/JAD-2009-1030. Review.

20.

Endothelial precursor cells and CRP on the RAGE: activation or cell death?

Yan SD, Bierhaus A, Nawroth PP, Stern DM.

J Cardiovasc Pharmacol. 2009 May;53(5):349-51. doi: 10.1097/FJC.0b013e31819d6188. No abstract available.

PMID:
19276986
21.

Circulating CD34-positive cells have prognostic value for neurologic function in patients with past cerebral infarction.

Taguchi A, Nakagomi N, Matsuyama T, Kikuchi-Taura A, Yoshikawa H, Kasahara Y, Hirose H, Moriwaki H, Nakagomi T, Soma T, Stern DM, Naritomi H.

J Cereb Blood Flow Metab. 2009 Jan;29(1):34-8. doi: 10.1038/jcbfm.2008.92. Epub 2008 Aug 13.

PMID:
18698330
22.

Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance autoimmune progression and diabetes onset in NOD mice.

Han J, Zhong J, Wei W, Wang Y, Huang Y, Yang P, Purohit S, Dong Z, Wang MH, She JX, Gong F, Stern DM, Wang CY.

Diabetes. 2008 Aug;57(8):2118-27. doi: 10.2337/db07-1499. Epub 2008 May 13.

23.

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, Domenici L.

J Neurosci. 2008 Mar 26;28(13):3521-30. doi: 10.1523/JNEUROSCI.0204-08.2008.

24.

Increase in circulating CD34-positive cells in patients with angiographic evidence of moyamoya-like vessels.

Yoshihara T, Taguchi A, Matsuyama T, Shimizu Y, Kikuchi-Taura A, Soma T, Stern DM, Yoshikawa H, Kasahara Y, Moriwaki H, Nagatsuka K, Naritomi H.

J Cereb Blood Flow Metab. 2008 Jun;28(6):1086-9. doi: 10.1038/jcbfm.2008.1. Epub 2008 Jan 30.

PMID:
18231114
25.

Angiotensin II-induced signaling pathways in diabetes.

Marrero MB, Fulton D, Stepp D, Stern DM.

Curr Diabetes Rev. 2005 May;1(2):197-202. Review.

PMID:
18220595
26.

Circulating CD34-positive cells provide a marker of vascular risk associated with cognitive impairment.

Taguchi A, Matsuyama T, Nakagomi T, Shimizu Y, Fukunaga R, Tatsumi Y, Yoshikawa H, Kikuchi-Taura A, Soma T, Moriwaki H, Nagatsuka K, Stern DM, Naritomi H.

J Cereb Blood Flow Metab. 2008 Mar;28(3):445-9. Epub 2007 Aug 8.

PMID:
17684516
27.

Hippocampal CA1 cell loss in a non-human primate model of transient global ischemia: a pilot study.

Hara K, Yasuhara T, Matsukawa N, Maki M, Masuda T, Yu G, Xu L, Tambrallo L, Rodriguez NA, Stern DM, Kawase T, Yamashima T, Buccafusco JJ, Hess DC, Borlongan CV.

Brain Res Bull. 2007 Sep 14;74(1-3):164-71.

PMID:
17683803
28.

Soluble forms of RAGE: an index of vascular stress? A commentary on "Soluble RAGE in type 2 diabetes: association with oxidative stress".

Nawroth PP, Stern DM.

Free Radic Biol Med. 2007 Aug 15;43(4):506-10. Epub 2007 May 4. Review. No abstract available.

PMID:
17640560
29.

Granulocyte colony-stimulating factor has a negative effect on stroke outcome in a murine model.

Taguchi A, Wen Z, Myojin K, Yoshihara T, Nakagomi T, Nakayama D, Tanaka H, Soma T, Stern DM, Naritomi H, Matsuyama T.

Eur J Neurosci. 2007 Jul;26(1):126-33.

PMID:
17614944
30.

Visualization of intracerebral arteries by synchrotron radiation microangiography.

Myojin K, Taguchi A, Umetani K, Fukushima K, Nishiura N, Matsuyama T, Kimura H, Stern DM, Imai Y, Mori H.

AJNR Am J Neuroradiol. 2007 May;28(5):953-7.

31.

A new protocol for quantifying CD34(+) cells in peripheral blood of patients with cardiovascular disease.

Kikuchi-Taura A, Soma T, Matsuyama T, Stern DM, Taguchi A.

Tex Heart Inst J. 2006;33(4):427-9.

32.

RAGE in inflammation: a new therapeutic target?

Bierhaus A, Stern DM, Nawroth PP.

Curr Opin Investig Drugs. 2006 Nov;7(11):985-91. Review.

PMID:
17117586
33.

Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation.

Kitao Y, Imai Y, Ozawa K, Kataoka A, Ikeda T, Soda M, Nakimawa K, Kiyama H, Stern DM, Hori O, Wakamatsu K, Ito S, Itohara S, Takahashi R, Ogawa S.

Hum Mol Genet. 2007 Jan 1;16(1):50-60. Epub 2006 Nov 20.

PMID:
17116640
34.

Posttranslationally modified proteins as mediators of sustained intestinal inflammation.

Andrassy M, Igwe J, Autschbach F, Volz C, Remppis A, Neurath MF, Schleicher E, Humpert PM, Wendt T, Liliensiek B, Morcos M, Schiekofer S, Thiele K, Chen J, Kientsch-Engel R, Schmidt AM, Stremmel W, Stern DM, Katus HA, Nawroth PP, Bierhaus A.

Am J Pathol. 2006 Oct;169(4):1223-37.

35.

Mitochondrial amyloid-beta peptide: pathogenesis or late-phase development?

Yan SD, Xiong WC, Stern DM.

J Alzheimers Dis. 2006 Jul;9(2):127-37. Review.

PMID:
16873960
36.

A rat model of human FENIB (familial encephalopathy with neuroserpin inclusion bodies).

Takano K, Kitao Y, Inagi R, Momoi T, Matsuyama T, Miyata T, Yoneda Y, Iso H, Stern DM, Hori O, Ogawa S.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):1040-7. Epub 2006 Jun 12.

PMID:
16782060
37.

Deletion of SERP1/RAMP4, a component of the endoplasmic reticulum (ER) translocation sites, leads to ER stress.

Hori O, Miyazaki M, Tamatani T, Ozawa K, Takano K, Okabe M, Ikawa M, Hartmann E, Mai P, Stern DM, Kitao Y, Ogawa S.

Mol Cell Biol. 2006 Jun;26(11):4257-67.

38.

Regulation of osteoclast function and bone mass by RAGE.

Zhou Z, Immel D, Xi CX, Bierhaus A, Feng X, Mei L, Nawroth P, Stern DM, Xiong WC.

J Exp Med. 2006 Apr 17;203(4):1067-80. Epub 2006 Apr 10.

39.

Role of the JAK/STAT signaling pathway in diabetic nephropathy.

Marrero MB, Banes-Berceli AK, Stern DM, Eaton DC.

Am J Physiol Renal Physiol. 2006 Apr;290(4):F762-8. Review.

40.

Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells.

Banes-Berceli AK, Shaw S, Ma G, Brands M, Eaton DC, Stern DM, Fulton D, Caldwell RW, Marrero MB.

Am J Physiol Renal Physiol. 2006 Jul;291(1):F116-21. Epub 2006 Jan 31.

41.

Disordered osteoclast formation in RAGE-deficient mouse establishes an essential role for RAGE in diabetes related bone loss.

Ding KH, Wang ZZ, Hamrick MW, Deng ZB, Zhou L, Kang B, Yan SL, She JX, Stern DM, Isales CM, Mi QS.

Biochem Biophys Res Commun. 2006 Feb 24;340(4):1091-7. Epub 2005 Dec 27.

PMID:
16403440
42.

RAGE and its ligands: a lasting memory in diabetic complications?

Yan SF, Ramasamy R, Bucciarelli LG, Wendt T, Lee LK, Hudson BI, Stern DM, Lalla E, DU Yan S, Rong LL, Naka Y, Schmidt AM.

Diab Vasc Dis Res. 2004 May;1(1):10-20. Review.

PMID:
16305050
43.

Hyperglycemia and reactive oxygen species mediate apoptosis in aortic endothelial cells through Janus kinase 2.

Tawfik A, Jin L, Banes-Berceli AK, Caldwell RB, Ogbi S, Shirley A, Barber D, Catravas JD, Stern DM, Fulton D, Caldwell RW, Marrero MB.

Vascul Pharmacol. 2005 Nov;43(5):320-6. Epub 2005 Oct 27.

PMID:
16257269
44.

The marriage of glucose and blood vessels: it isn't all that sweet.

Xiong WC, Stern DM.

Cell Metab. 2005 Oct;2(4):212-5.

45.

Understanding RAGE, the receptor for advanced glycation end products.

Bierhaus A, Humpert PM, Morcos M, Wendt T, Chavakis T, Arnold B, Stern DM, Nawroth PP.

J Mol Med (Berl). 2005 Nov;83(11):876-86. Epub 2005 Aug 24. Review.

PMID:
16133426
46.

Advanced glycation end product receptor-mediated cellular dysfunction.

Bierhaus A, Humpert PM, Stern DM, Arnold B, Nawroth PP.

Ann N Y Acad Sci. 2005 Jun;1043:676-80. Review.

PMID:
16037292
47.

Tissue factor as a link between wounding and tissue repair.

Chen J, Kasper M, Heck T, Nakagawa K, Humpert PM, Bai L, Wu G, Zhang Y, Luther T, Andrassy M, Schiekofer S, Hamann A, Morcos M, Chen B, Stern DM, Nawroth PP, Bierhaus A.

Diabetes. 2005 Jul;54(7):2143-54.

48.

Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease.

Lue LF, Yan SD, Stern DM, Walker DG.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):249-66. Review.

PMID:
15975028
49.
50.

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.

Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I.

J Clin Invest. 2005 May;115(5):1267-74. Epub 2005 Apr 14.

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