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Three-Dimensional Culture of Oral Progenitor Cells: Effects on small extracellular vesicles production and proliferative function.

Yang Y, Knight R, Stephens P, Zhang Y.

J Oral Pathol Med. 2019 Dec 1. doi: 10.1111/jop.12981. [Epub ahead of print]


High-flow oxygen for children's airway surgery: randomised controlled trial protocol (HAMSTER).

Humphreys S, von Ungern-Sternberg BS, Skowno J, Williams T, Taylor J, Taverner F, Gibbons K, Burgoyne L, Sommerfield D, Stephens P, Hallett B, Vijayasekaran S, Slee N, Burns H, Sowa M, Davidson A, Schibler A.

BMJ Open. 2019 Oct 14;9(10):e031873. doi: 10.1136/bmjopen-2019-031873.


The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.

Disel U, Madison R, Abhishek K, Chung JH, Trabucco SE, Matos AO, Frampton GM, Albacker LA, Reddy V, Karadurmus N, Benson A, Webster J, Paydas S, Cabanillas R, Nangia C, Ozturk MA, Millis SZ, Pal SK, Wilky B, Sokol ES, Gay LM, Soman S, Ganesan S, Janeway K, Stephens PJ, Zhu VW, Ou SI, Lovly CM, Gounder M, Schrock AB, Ross JS, Miller VA, Klempner SJ, Ali SM.

Oncologist. 2019 Oct 11. pii: theoncologist.2018-0528. doi: 10.1634/theoncologist.2018-0528. [Epub ahead of print]


Genomic profiling of cell-free circulating tumor DNA in patients with colorectal cancer and its fidelity to the genomics of the tumor biopsy.

Li G, Pavlick D, Chung JH, Bauer T, Tan BA, Peguero J, Ward P, Kallab A, Bufill J, Hoffman A, Sadiq A, Edenfield J, He J, Cooke M, Hughes J, Forcier B, Nahas M, Stephens P, Ali SM, Schrock AB, Ross JS, Miller VA, Gregg JP.

J Gastrointest Oncol. 2019 Oct;10(5):831-840. doi: 10.21037/jgo.2019.05.05.


Echocardiographic Screening of Cardiovascular Status in Pediatric Sickle Cell Disease.

Allen KY, Jones S, Jackson T, DeCost G, Stephens P, Hanna BD, Cohen MS, Smith-Whitley K, Mercer-Rosa L, Natarajan SS.

Pediatr Cardiol. 2019 Dec;40(8):1670-1678. doi: 10.1007/s00246-019-02202-3. Epub 2019 Sep 21.


Biodynamic excisional skin tension lines.

Sethu C, Troisi L, Stephens P.

Ann R Coll Surg Engl. 2019 Nov;101(8):622-623. doi: 10.1308/rcsann.2019.0115. Epub 2019 Sep 11. No abstract available.


Erratum to "Emergence of novel and dominant acquired EGFR solvent-front mutations at Gly796 (G796S/R) together with C797S/G and L792F/H mutations in one EGFR (L858R/T790M) NSCLC patient who progressed on osimertinib" [Lung Cancer, 108 (June 2017) 228-231].

Ou SI, Cui J, Schrock AB, Goldberg ME, Zhu VW, Albacker L, Stephens PJ, Miller VA, Ali SM.

Lung Cancer. 2019 Dec;138:141. doi: 10.1016/j.lungcan.2019.08.013. Epub 2019 Aug 22. No abstract available.


A Novel Next-Generation Sequencing Approach to Detecting Microsatellite Instability and Pan-Tumor Characterization of 1000 Microsatellite Instability-High Cases in 67,000 Patient Samples.

Trabucco SE, Gowen K, Maund SL, Sanford E, Fabrizio DA, Hall MJ, Yakirevich E, Gregg JP, Stephens PJ, Frampton GM, Hegde PS, Miller VA, Ross JS, Hartmaier RJ, Huang SA, Sun JX.

J Mol Diagn. 2019 Nov;21(6):1053-1066. doi: 10.1016/j.jmoldx.2019.06.011. Epub 2019 Aug 22.


The Brazilian private pharmaceutical market after the first ten years of the generics law.

Bertoldi AD, Wagner AK, Emmerick ICM, Chaves LA, Stephens P, Ross-Degnan D.

J Pharm Policy Pract. 2019 Aug 14;12:18. doi: 10.1186/s40545-019-0179-9. eCollection 2019.


Using the Multitheory Model to Predict Initiation and Sustenance of Physical Activity Behavior Among Osteopathic Medical Students.

Nahar VK, Wilkerson AH, Stephens PM, Kim RW, Sharma M.

J Am Osteopath Assoc. 2019 Aug 1;119(8):479-487. doi: 10.7556/jaoa.2019.089.


Acridine form IX.

Stephens PW, Schur E, Lapidus SH, Bernstein J.

Acta Crystallogr E Crystallogr Commun. 2019 Mar 26;75(Pt 4):489-491. doi: 10.1107/S2056989019003645. eCollection 2019 Apr 1.


What factors explain the geographical range of mammalian parasites?

Byers JE, Schmidt JP, Pappalardo P, Haas SE, Stephens PR.

Proc Biol Sci. 2019 May 29;286(1903):20190673. doi: 10.1098/rspb.2019.0673.


Utilizing Multi-Theory Model in Determining Intentions to Smoking Cessation Among Smokers.

Nahar VK, Wilkerson AH, Patel FC, Kim RW, Stephens PM, Sharma M.

Tob Use Insights. 2019 Apr 26;12:1179173X19843524. doi: 10.1177/1179173X19843524. eCollection 2019.


Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study.

Sicklick JK, Kato S, Okamura R, Schwaederle M, Hahn ME, Williams CB, De P, Krie A, Piccioni DE, Miller VA, Ross JS, Benson A, Webster J, Stephens PJ, Lee JJ, Fanta PT, Lippman SM, Leyland-Jones B, Kurzrock R.

Nat Med. 2019 May;25(5):744-750. doi: 10.1038/s41591-019-0407-5. Epub 2019 Apr 22.


Joint effects of weather and interspecific competition on foraging behavior and survival of a mountain herbivore.

Ferretti F, Lovari S, Stephens PA.

Curr Zool. 2019 Apr;65(2):165-175. doi: 10.1093/cz/zoy032. Epub 2018 May 14.


Parasite sharing in wild ungulates and their predators: Effects of phylogeny, range overlap, and trophic links.

Stephens PR, Altizer S, Ezenwa VO, Gittleman JL, Moan E, Han B, Huang S, Pappalardo P.

J Anim Ecol. 2019 Jul;88(7):1017-1028. doi: 10.1111/1365-2656.12987. Epub 2019 Apr 15.


Estimating global trends in total and childhood antibiotic consumption, 2011-2015.

Jackson C, Hsia Y, Bielicki JA, Ellis S, Stephens P, Wong ICK, Sharland M.

BMJ Glob Health. 2019 Feb 27;4(1):e001241. doi: 10.1136/bmjgh-2018-001241. eCollection 2019.


Repair of Total Anomalous Pulmonary Venous Connection: Risk Factors for Postoperative Obstruction.

White BR, Ho DY, Faerber JA, Katcoff H, Glatz AC, Mascio CE, Stephens P Jr, Cohen MS.

Ann Thorac Surg. 2019 Jul;108(1):122-129. doi: 10.1016/j.athoracsur.2019.02.017. Epub 2019 Mar 16.


Correction: RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors.

Loi S, Dushyanthen S, Beavis PA, Salgado R, Denkert C, Savas P, Combs S, Rimm DL, Giltnane JM, Estrada MV, Sánchez V, Sanders ME, Cook RS, Pilkinton MA, Mallal SA, Wang K, Miller VA, Stephens PJ, Yelensky R, Doimi FD, Gómez H, Ryzhov SV, Darcy PK, Arteaga CL, Balko JM.

Clin Cancer Res. 2019 Feb 15;25(4):1437. doi: 10.1158/1078-0432.CCR-18-4264. No abstract available.


The limits to population density in birds and mammals.

Stephens PA, Vieira MV, Willis SG, Carbone C.

Ecol Lett. 2019 Apr;22(4):654-663. doi: 10.1111/ele.13227. Epub 2019 Feb 6.


Tumor mutational burden and response to programmed cell death protein 1 inhibitors in a case series of patients with metastatic desmoplastic melanoma.

Boussemart L, Johnson A, Schrock AB, Pal SK, Frampton GM, Fabrizio D, Chalmers Z, Lotem M, Gibney G, Russell J, Chmielowski B, Ross JS, Stephens PJ, Miller VA, Ali SM.

J Am Acad Dermatol. 2019 Jun;80(6):1780-1782. doi: 10.1016/j.jaad.2018.12.020. Epub 2018 Dec 18. No abstract available.


Ecology: Luck, Scarcity, and the Fate of Populations.

Stephens PA.

Curr Biol. 2018 Dec 17;28(24):R1384-R1386. doi: 10.1016/j.cub.2018.10.059.


Anomalous Stoichiometry, 3-D Bridged Triangular/Pentagonal Layered Structured Artificial Antiferromagnet for the Prussian Blue Analogue A3MnII5(CN)13 (A = NMe4, NEtMe3). A Cation Adaptive Structure.

Lapidus SH, Graham AG, Kareis CM, Hawkins CG, Stephens PW, Miller JS.

J Am Chem Soc. 2019 Jan 16;141(2):911-921. doi: 10.1021/jacs.8b10638. Epub 2019 Jan 4.


Hydrating the Bispropionate Notch in Malaria Pigment: A New Structural Motif in the Iron(III)(deuteroporphyrin) Dimer.

Kuter D, Suárez L, Dodd EL, Noll BC, Stephens PW, Bohle DS.

Chemistry. 2019 Mar 21;25(17):4373-4378. doi: 10.1002/chem.201805116. Epub 2019 Feb 27.


Multiple configurations of EGFR exon 20 resistance mutations after first- and third-generation EGFR TKI treatment affect treatment options in NSCLC.

Goldberg ME, Montesion M, Young L, Suh J, Greenbowe J, Kennedy M, Giaccone G, Akerley WL, Dowlati A, Creelan BC, Hicks JK, Hesketh PJ, Kelly KL, Riess JW, Miller VA, Stephens PJ, Frampton GM, Ali S, Gregg JP, Albacker LA.

PLoS One. 2018 Nov 27;13(11):e0208097. doi: 10.1371/journal.pone.0208097. eCollection 2018.


Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer.

Sokol ES, Feng YX, Jin DX, Basudan A, Lee AV, Atkinson JM, Chen J, Stephens PJ, Frampton GM, Gupta PB, Ross JS, Chung JH, Oesterreich S, Ali SM, Hartmaier RJ.

Ann Oncol. 2019 Jan 1;30(1):115-123. doi: 10.1093/annonc/mdy497.


Synthesis and antibacterial profiles of targeted triclosan derivatives.

Howse GL, Bovill RA, Stephens PJ, Osborn HMI.

Eur J Med Chem. 2019 Jan 15;162:51-58. doi: 10.1016/j.ejmech.2018.10.053. Epub 2018 Oct 23.


Clinical utility of tumor genomic profiling in patients with high plasma circulating tumor DNA burden or metabolically active tumors.

Zhou C, Yuan Z, Ma W, Qi L, Mahavongtrakul A, Li Y, Li H, Gong J, Fan RR, Li J, Molmen M, Clark TA, Pavlick D, Frampton GM, Forcier B, Moore EH, Shelton DK, Cooke M, Ali SM, Miller VA, Gregg JP, Stephens PJ, Li T.

J Hematol Oncol. 2018 Nov 6;11(1):129. doi: 10.1186/s13045-018-0671-8.


Genomic Profiling of Parathyroid Carcinoma Reveals Genomic Alterations Suggesting Benefit from Therapy.

Kang H, Pettinga D, Schubert AD, Ladenson PW, Ball DW, Chung JH, Schrock AB, Madison R, Frampton GM, Stephens PJ, Ross JS, Miller VA, Ali SM.

Oncologist. 2019 Jun;24(6):791-797. doi: 10.1634/theoncologist.2018-0334. Epub 2018 Oct 29.


Hybrid Capture-Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Non-Small Cell Lung Cancer.

Schrock AB, Welsh A, Chung JH, Pavlick D, Bernicker EH, Creelan BC, Forcier B, Ross JS, Stephens PJ, Ali SM, Dagogo-Jack I, Shaw AT, Li T, Ou SI, Miller VA.

J Thorac Oncol. 2019 Feb;14(2):255-264. doi: 10.1016/j.jtho.2018.10.008. Epub 2018 Oct 24.


Comparative Genomic Profiling of Refractory and Metastatic Penile and Nonpenile Cutaneous Squamous Cell Carcinoma: Implications for Selection of Systemic Therapy.

Jacob JM, Ferry EK, Gay LM, Elvin JA, Vergilio JA, Ramkissoon S, Severson E, Necchi A, Killian JK, Ali SM, Schrock AB, Liu NW, Chung J, Miller VA, Stephens PJ, Welsh A, Corona RJ, Ross JS, Bratslavsky G.

J Urol. 2019 Mar;201(3):541-548. doi: 10.1016/j.juro.2018.09.056.


Anomalous Stoichiometry and Antiferromagnetic Ordering for the Extended Hydroxymanganese(II) Cubes/Hexacyanometalate-Based 3D-Structured [MnII 4 (OH)4 ][MnII (CN)6 ](OH2 )6 ⋅H2 O.

Lapidus SH, Stephens PW, Kareis CM, VanNatta PE, Miller JS.

Chemistry. 2019 Feb 1;25(7):1752-1757. doi: 10.1002/chem.201804935. Epub 2019 Jan 8.


Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition.

Fabrizio DA, George TJ Jr, Dunne RF, Frampton G, Sun J, Gowen K, Kennedy M, Greenbowe J, Schrock AB, Hezel AF, Ross JS, Stephens PJ, Ali SM, Miller VA, Fakih M, Klempner SJ.

J Gastrointest Oncol. 2018 Aug;9(4):610-617. doi: 10.21037/jgo.2018.05.06.


Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden.

Liang WS, Vergilio JA, Salhia B, Huang HJ, Oki Y, Garrido-Laguna I, Park H, Westin JR, Meric-Bernstam F, Fabrizio D, Miller VA, Stephens PJ, Fanale MA, Ross JS, Janku F.

Oncologist. 2019 Feb;24(2):219-228. doi: 10.1634/theoncologist.2018-0058. Epub 2018 Aug 14.


Genomic Profiling of T-Cell Neoplasms Reveals Frequent JAK1 and JAK3 Mutations With Clonal Evasion From Targeted Therapies.

Greenplate A, Wang K, Tripathi RM, Palma N, Ali SM, Stephens PJ, Miller VA, Shyr Y, Guo Y, Reddy NM, Kozhaya L, Unutmaz D, Chen X, Irish JM, Davé UP.

JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.17.00019. Epub 2018 Feb 13.


Using a Multitheory Model to Predict Initiation and Sustenance of Fruit and Vegetable Consumption Among College Students.

Sharma M, Stephens PM, Nahar VK, Catalano HP, Lingam VC, Ford MA.

J Am Osteopath Assoc. 2018 Aug 1;118(8):507-517. doi: 10.7556/jaoa.2018.119.


Diverse EGFR Exon 20 Insertions and Co-Occurring Molecular Alterations Identified by Comprehensive Genomic Profiling of NSCLC.

Riess JW, Gandara DR, Frampton GM, Madison R, Peled N, Bufill JA, Dy GK, Ou SI, Stephens PJ, McPherson JD, Lara PN Jr, Burich RA, Ross JS, Miller VA, Ali SM, Mack PC, Schrock AB.

J Thorac Oncol. 2018 Oct;13(10):1560-1568. doi: 10.1016/j.jtho.2018.06.019. Epub 2018 Jul 5.


Skin Cancer Knowledge, Attitudes, and Practices among Chinese Population: A Narrative Review.

Stephens PM, Martin B, Ghafari G, Luong J, Nahar VK, Pham L, Luo J, Savoy M, Sharma M.

Dermatol Res Pract. 2018 Jun 4;2018:1965674. doi: 10.1155/2018/1965674. eCollection 2018. Review.


Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

Clark TA, Chung JH, Kennedy M, Hughes JD, Chennagiri N, Lieber DS, Fendler B, Young L, Zhao M, Coyne M, Breese V, Young G, Donahue A, Pavlick D, Tsiros A, Brennan T, Zhong S, Mughal T, Bailey M, He J, Roels S, Frampton GM, Spoerke JM, Gendreau S, Lackner M, Schleifman E, Peters E, Ross JS, Ali SM, Miller VA, Gregg JP, Stephens PJ, Welsh A, Otto GA, Lipson D.

J Mol Diagn. 2018 Sep;20(5):686-702. doi: 10.1016/j.jmoldx.2018.05.004. Epub 2018 Jun 22.


Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling.

Tarlock K, Zhong S, He Y, Ries R, Severson E, Bailey M, Morley S, Balasubramanian S, Erlich R, Lipson D, Otto GA, Vergillo JA, Kolb EA, Ross JS, Mughal T, Stephens PJ, Miller V, Meshinchi S, He J.

Oncotarget. 2018 May 29;9(41):26417-26430. doi: 10.18632/oncotarget.25443. eCollection 2018 May 29.


Postoperative Obstruction of the Pulmonary Veins in Mixed Total Anomalous Pulmonary Venous Connection.

Ho DY, White BR, Glatz AC, Mascio CE, Stephens P Jr, Cohen MS.

Pediatr Cardiol. 2018 Oct;39(7):1489-1495. doi: 10.1007/s00246-018-1921-9. Epub 2018 Jun 5.


Response to rapamycin analogs but not PD-1 inhibitors in PTEN-mutated metastatic non-small-cell lung cancer with high tumor mutational burden.

Parikh AR, Ali SM, Schrock AB, Albacker LA, Miller VA, Stephens PJ, Crilley P, Markman M.

Lung Cancer (Auckl). 2018 May 18;9:45-47. doi: 10.2147/LCTT.S161738. eCollection 2018.


Influencing Health Behavior Change Related to Musculoskeletal Conditions: The Need to Expand the Evidence Base and the Case for Multitheory Model.

Kim RW, Stephens PM, Nahar VK, Sharma M.

Am J Phys Med Rehabil. 2018 Dec;97(12):933-934. doi: 10.1097/PHM.0000000000000968. No abstract available.


STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung Adenocarcinoma.

Skoulidis F, Goldberg ME, Greenawalt DM, Hellmann MD, Awad MM, Gainor JF, Schrock AB, Hartmaier RJ, Trabucco SE, Gay L, Ali SM, Elvin JA, Singal G, Ross JS, Fabrizio D, Szabo PM, Chang H, Sasson A, Srinivasan S, Kirov S, Szustakowski J, Vitazka P, Edwards R, Bufill JA, Sharma N, Ou SI, Peled N, Spigel DR, Rizvi H, Aguilar EJ, Carter BW, Erasmus J, Halpenny DF, Plodkowski AJ, Long NM, Nishino M, Denning WL, Galan-Cobo A, Hamdi H, Hirz T, Tong P, Wang J, Rodriguez-Canales J, Villalobos PA, Parra ER, Kalhor N, Sholl LM, Sauter JL, Jungbluth AA, Mino-Kenudson M, Azimi R, Elamin YY, Zhang J, Leonardi GC, Jiang F, Wong KK, Lee JJ, Papadimitrakopoulou VA, Wistuba II, Miller VA, Frampton GM, Wolchok JD, Shaw AT, Jänne PA, Stephens PJ, Rudin CM, Geese WJ, Albacker LA, Heymach JV.

Cancer Discov. 2018 Jul;8(7):822-835. doi: 10.1158/2159-8290.CD-18-0099. Epub 2018 May 17.


Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma.

de Velasco G, Wankowicz SA, Madison R, Ali SM, Norton C, Duquette A, Ross JS, Bossé D, Lalani AA, Miller VA, Stephens PJ, Young L, Hakimi AA, Signoretti S, Pal SK, Choueiri TK.

Br J Cancer. 2018 May;118(9):1238-1242. doi: 10.1038/s41416-018-0064-3. Epub 2018 Apr 20.


Kinase domain activation through gene rearrangement in multiple myeloma.

Morgan GJ, He J, Tytarenko R, Patel P, Stephens OW, Zhong S, Deshpande S, Bauer M, Weinhold N, Schinke C, Rasche L, Bailey M, Ali S, Ross J, Miller VA, Stephens P, Thanendrarajan S, Zangari M, van Rhee F, Mughal T, Davies FE, Walker BA.

Leukemia. 2018 Nov;32(11):2435-2444. doi: 10.1038/s41375-018-0108-y. Epub 2018 Mar 23.


Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK.

Oncologist. 2018 Sep;23(9):998-1003. doi: 10.1634/theoncologist.2017-0645. Epub 2018 Apr 5.


Development and Characterisation of a Human Chronic Skin Wound Cell Line-Towards an Alternative for Animal Experimentation.

Caley M, Wall IB, Peake M, Kipling D, Giles P, Thomas DW, Stephens P.

Int J Mol Sci. 2018 Mar 27;19(4). pii: E1001. doi: 10.3390/ijms19041001.


Label-free quantitative chemical imaging and classification analysis of adipogenesis using mouse embryonic stem cells.

Masia F, Glen A, Stephens P, Langbein W, Borri P.

J Biophotonics. 2018 Jul;11(7):e201700219. doi: 10.1002/jbio.201700219. Epub 2018 Apr 19.


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