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Items: 1 to 50 of 97


Modelling the ballistic-to-diffusive transition in nematode motility reveals variation in exploratory behaviour across species.

Helms SJ, Rozemuller WM, Costa AC, Avery L, Stephens GJ, Shimizu TS.

J R Soc Interface. 2019 Aug 30;16(157):20190174. doi: 10.1098/rsif.2019.0174. Epub 2019 Aug 28.


The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca2+-Activated K+ Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing.

Tabatabaee S, Baker D, Selwood DL, Whalley BJ, Stephens GJ.

Pharmaceuticals (Basel). 2019 Jul 4;12(3). pii: E104. doi: 10.3390/ph12030104.


CACHD1: A new activity-modifying protein for voltage-gated calcium channels.

Stephens GJ, Cottrell GS.

Channels (Austin). 2019 Dec;13(1):120-123. doi: 10.1080/19336950.2019.1600968. No abstract available.


Adaptive, locally linear models of complex dynamics.

Costa AC, Ahamed T, Stephens GJ.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1501-1510. doi: 10.1073/pnas.1813476116. Epub 2019 Jan 17.


CACHD1 is an α2δ-Like Protein That Modulates CaV3 Voltage-Gated Calcium Channel Activity.

Cottrell GS, Soubrane CH, Hounshell JA, Lin H, Owenson V, Rigby M, Cox PJ, Barker BS, Ottolini M, Ince S, Bauer CC, Perez-Reyes E, Patel MK, Stevens EB, Stephens GJ.

J Neurosci. 2018 Oct 24;38(43):9186-9201. doi: 10.1523/JNEUROSCI.3572-15.2018. Epub 2018 Sep 4.


Recent advances in targeting ion channels to treat chronic pain.

Stevens EB, Stephens GJ.

Br J Pharmacol. 2018 Jun;175(12):2133-2137. doi: 10.1111/bph.14215.


Species-specific susceptibility to cannabis-induced convulsions.

Whalley BJ, Lin H, Bell L, Hill T, Patel A, Gray RA, Elizabeth Roberts C, Devinsky O, Bazelot M, Williams CM, Stephens GJ.

Br J Pharmacol. 2019 May;176(10):1506-1523. doi: 10.1111/bph.14165. Epub 2018 Mar 25.


Exploiting ecology in drug pulse sequences in favour of population reduction.

Bauer M, Graf IR, Ngampruetikorn V, Stephens GJ, Frey E.

PLoS Comput Biol. 2017 Sep 28;13(9):e1005747. doi: 10.1371/journal.pcbi.1005747. eCollection 2017 Sep.


A Brain on a Roller Coaster: Can the Dopamine Reward System Act as a Protagonist to Subdue the Ups and Downs of Bipolar Disorder?

Arjmand S, Behzadi M, Stephens GJ, Ezzatabadipour S, Seifaddini R, Arjmand S, Shabani M.

Neuroscientist. 2018 Oct;24(5):423-439. doi: 10.1177/1073858417714226. Epub 2017 Jun 14.


Bias, belief, and consensus: Collective opinion formation on fluctuating networks.

Ngampruetikorn V, Stephens GJ.

Phys Rev E. 2016 Nov;94(5-1):052312. Epub 2016 Nov 18.


Resolving coiled shapes reveals new reorientation behaviors in C. elegans.

Broekmans OD, Rodgers JB, Ryu WS, Stephens GJ.

Elife. 2016 Sep 20;5. pii: e17227. doi: 10.7554/eLife.17227.


Hierarchical compression of Caenorhabditis elegans locomotion reveals phenotypic differences in the organization of behaviour.

Gomez-Marin A, Stephens GJ, Brown AE.

J R Soc Interface. 2016 Aug;13(121). pii: 20160466. doi: 10.1098/rsif.2016.0466.


DNA Twist Stability Changes with Magnesium(2+) Concentration.

Broekmans OD, King GA, Stephens GJ, Wuite GJ.

Phys Rev Lett. 2016 Jun 24;116(25):258102. doi: 10.1103/PhysRevLett.116.258102. Epub 2016 Jun 21.


Does modulation of the endocannabinoid system have potential therapeutic utility in cerebellar ataxia?

Stephens GJ.

J Physiol. 2016 Aug 15;594(16):4631-41. doi: 10.1113/JP271106. Epub 2016 Jun 8. Review.


Cannabinoids and Tremor Induced by Motor-related Disorders: Friend or Foe?

Arjmand S, Vaziri Z, Behzadi M, Abbassian H, Stephens GJ, Shabani M.

Neurotherapeutics. 2015 Oct;12(4):778-87. doi: 10.1007/s13311-015-0367-5. Review.


Synaptic vesicle glycoprotein 2A modulates vesicular release and calcium channel function at peripheral sympathetic synapses.

Vogl C, Tanifuji S, Danis B, Daniels V, Foerch P, Wolff C, Whalley BJ, Mochida S, Stephens GJ.

Eur J Neurosci. 2015 Feb;41(4):398-409. doi: 10.1111/ejn.12799. Epub 2014 Dec 8.


Exogenous α-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release.

Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova TD, Mus LV, Soubrane CH, Dallas ML, Thalhammer A, Cingolani LA, Mochida S, Gainetdinov RR, Stephens GJ, Chieregatti E.

J Neurosci. 2014 Aug 6;34(32):10603-15. doi: 10.1523/JNEUROSCI.0608-14.2014.


Nonpsychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability.

Iannotti FA, Hill CL, Leo A, Alhusaini A, Soubrane C, Mazzarella E, Russo E, Whalley BJ, Di Marzo V, Stephens GJ.

ACS Chem Neurosci. 2014 Nov 19;5(11):1131-41. doi: 10.1021/cn5000524. Epub 2014 Jul 29.


The influence of interimplant divergence on the retention characteristics of locator attachments, a laboratory study.

Stephens GJ, di Vitale N, O'Sullivan E, McDonald A.

J Prosthodont. 2014 Aug;23(6):467-75. doi: 10.1111/jopr.12144. Epub 2014 Apr 21.


Voltage-gated sodium (NaV) channel blockade by plant cannabinoids does not confer anticonvulsant effects per se.

Hill AJ, Jones NA, Smith I, Hill CL, Williams CM, Stephens GJ, Whalley BJ.

Neurosci Lett. 2014 Apr 30;566:269-74. doi: 10.1016/j.neulet.2014.03.013. Epub 2014 Mar 16.


Phorbol ester modulation of Ca2+ channels mediates nociceptive transmission in dorsal horn neurones.

Yang L, Topia I, Schneider T, Stephens GJ.

Pharmaceuticals (Basel). 2013 May 29;6(6):777-87. doi: 10.3390/ph6060777.


A place for time: the spatiotemporal structure of neural dynamics during natural audition.

Stephens GJ, Honey CJ, Hasson U.

J Neurophysiol. 2013 Nov;110(9):2019-26. doi: 10.1152/jn.00268.2013. Epub 2013 Aug 7.


Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia.

Silveirinha V, Stephens GJ, Cimarosti H.

J Neurochem. 2013 Dec;127(5):580-91. doi: 10.1111/jnc.12347. Epub 2013 Jul 19. Review.


The du(2J) mouse model of ataxia and absence epilepsy has deficient cannabinoid CB₁ receptor-mediated signalling.

Wang X, Whalley BJ, Stephens GJ.

J Physiol. 2013 Aug 15;591(16):3919-33. doi: 10.1113/jphysiol.2012.244947. Epub 2013 Jun 3.


Statistical thermodynamics of natural images.

Stephens GJ, Mora T, Tkačik G, Bialek W.

Phys Rev Lett. 2013 Jan 4;110(1):018701. Epub 2013 Jan 2.


CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.

Baillie GL, Horswill JG, Anavi-Goffer S, Reggio PH, Bolognini D, Abood ME, McAllister S, Strange PG, Stephens GJ, Pertwee RG, Ross RA.

Mol Pharmacol. 2013 Feb;83(2):322-38. doi: 10.1124/mol.112.080879. Epub 2012 Nov 15.


Cannabidivarin is anticonvulsant in mouse and rat.

Hill AJ, Mercier MS, Hill TD, Glyn SE, Jones NA, Yamasaki Y, Futamura T, Duncan M, Stott CG, Stephens GJ, Williams CM, Whalley BJ.

Br J Pharmacol. 2012 Dec;167(8):1629-42. doi: 10.1111/j.1476-5381.2012.02207.x.


Automated tracking of animal posture and movement during exploration and sensory orientation behaviors.

Gomez-Marin A, Partoune N, Stephens GJ, Louis M.

PLoS One. 2012;7(8):e41642. doi: 10.1371/journal.pone.0041642. Epub 2012 Aug 9. Erratum in: PLoS One. 2012;7(10). doi:10.1371/annotation/5bef5b0a-9b48-4e85-8df5-a46793f6c701. PLoS One. 2012;7(11). doi:10.1371/annotation/41b2d3fd-e816-420c-80d0-88290796b1cd. Brembs, Björn [added].


The synaptic vesicle glycoprotein 2A ligand levetiracetam inhibits presynaptic Ca2+ channels through an intracellular pathway.

Vogl C, Mochida S, Wolff C, Whalley BJ, Stephens GJ.

Mol Pharmacol. 2012 Aug;82(2):199-208. doi: 10.1124/mol.111.076687. Epub 2012 May 3.


Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

Jones NA, Glyn SE, Akiyama S, Hill TD, Hill AJ, Weston SE, Burnett MD, Yamasaki Y, Stephens GJ, Whalley BJ, Williams CM.

Seizure. 2012 Jun;21(5):344-52. doi: 10.1016/j.seizure.2012.03.001. Epub 2012 Apr 19.


Phytocannabinoids as novel therapeutic agents in CNS disorders.

Hill AJ, Williams CM, Whalley BJ, Stephens GJ.

Pharmacol Ther. 2012 Jan;133(1):79-97. doi: 10.1016/j.pharmthera.2011.09.002. Epub 2011 Sep 6. Review.


Active sampling and decision making in Drosophila chemotaxis.

Gomez-Marin A, Stephens GJ, Louis M.

Nat Commun. 2011 Aug 23;2:441. doi: 10.1038/ncomms1455.


Inhibition of synaptic transmission and G protein modulation by synthetic CaV2.2 Ca²+ channel peptides.

Bucci G, Mochida S, Stephens GJ.

J Physiol. 2011 Jul 1;589(Pt 13):3085-101. doi: 10.1113/jphysiol.2010.204735. Epub 2011 Apr 26.


Emergence of long timescales and stereotyped behaviors in Caenorhabditis elegans.

Stephens GJ, Bueno de Mesquita M, Ryu WS, Bialek W.

Proc Natl Acad Sci U S A. 2011 May 3;108(18):7286-9. doi: 10.1073/pnas.1007868108. Epub 2011 Apr 18.


Searching for simplicity in the analysis of neurons and behavior.

Stephens GJ, Osborne LC, Bialek W.

Proc Natl Acad Sci U S A. 2011 Sep 13;108 Suppl 3:15565-71. doi: 10.1073/pnas.1010868108. Epub 2011 Mar 7. Review.


WITHDRAWN: Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures.

Jones NA, Hill AJ, Weston SE, Burnett MD, Stephens GJ, Whalley BJ, Williams CM.

Seizure. 2011 Jan 6. [Epub ahead of print]


Effects of the allosteric antagonist 1-(4-chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 receptor modulation in the cerebellum.

Wang X, Horswill JG, Whalley BJ, Stephens GJ.

Mol Pharmacol. 2011 Apr;79(4):758-67. doi: 10.1124/mol.110.068197. Epub 2010 Dec 28.


From modes to movement in the behavior of Caenorhabditis elegans.

Stephens GJ, Johnson-Kerner B, Bialek W, Ryu WS.

PLoS One. 2010 Nov 16;5(11):e13914. doi: 10.1371/journal.pone.0013914.


Statistical mechanics of letters in words.

Stephens GJ, Bialek W.

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Jun;81(6 Pt 2):066119. Epub 2010 Jun 25.


Speaker-listener neural coupling underlies successful communication.

Stephens GJ, Silbert LJ, Hasson U.

Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14425-30. doi: 10.1073/pnas.1008662107. Epub 2010 Jul 26.


Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats.

Hill AJ, Weston SE, Jones NA, Smith I, Bevan SA, Williamson EM, Stephens GJ, Williams CM, Whalley BJ.

Epilepsia. 2010 Aug;51(8):1522-32. doi: 10.1111/j.1528-1167.2010.02523.x. Epub 2010 Feb 26.


Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo.

Jones NA, Hill AJ, Smith I, Bevan SA, Williams CM, Whalley BJ, Stephens GJ.

J Pharmacol Exp Ther. 2010 Feb;332(2):569-77. doi: 10.1124/jpet.109.159145. Epub 2009 Nov 11.


Development of multi-electrode array screening for anticonvulsants in acute rat brain slices.

Hill AJ, Jones NA, Williams CM, Stephens GJ, Whalley BJ.

J Neurosci Methods. 2010 Jan 15;185(2):246-56. doi: 10.1016/j.jneumeth.2009.10.007. Epub 2009 Oct 28.


Effects of neuropathy on high-voltage-activated Ca(2+) current in sensory neurones.

Yang L, Stephens GJ.

Cell Calcium. 2009 Oct;46(4):248-56. doi: 10.1016/j.ceca.2009.08.001. Epub 2009 Sep 1.


G-protein-coupled-receptor-mediated presynaptic inhibition in the cerebellum.

Stephens GJ.

Trends Pharmacol Sci. 2009 Aug;30(8):421-30. doi: 10.1016/ Epub 2009 Jul 24. Review.


A cost-effective high-throughput digital system for observation and acquisition of animal behavioral data.

Farrimond JA, Hill AJ, Jones NA, Stephens GJ, Whalley BJ, Williams CM.

Behav Res Methods. 2009 May;41(2):446-51. doi: 10.3758/BRM.41.2.446.


Investigation of the effects of the novel anticonvulsant compound carisbamate (RWJ-333369) on rat piriform cortical neurones in vitro.

Whalley BJ, Stephens GJ, Constanti A.

Br J Pharmacol. 2009 Mar;156(6):994-1008. doi: 10.1111/j.1476-5381.2008.00110.x.


Nerve Terminal GABAA Receptors Activate Ca2+/Calmodulin-dependent Signaling to Inhibit Voltage-gated Ca2+ Influx and Glutamate Release.

Long P, Mercer A, Begum R, Stephens GJ, Sihra TS, Jovanovic JN.

J Biol Chem. 2009 Mar 27;284(13):8726-37. doi: 10.1074/jbc.M805322200. Epub 2009 Jan 13.


Optogenetic analysis of synaptic function.

Liewald JF, Brauner M, Stephens GJ, Bouhours M, Schultheis C, Zhen M, Gottschalk A.

Nat Methods. 2008 Oct;5(10):895-902. doi: 10.1038/nmeth.1252. Epub 2008 Sep 14.


Effects of Delta9-tetrahydrocannabivarin on [35S]GTPgammaS binding in mouse brain cerebellum and piriform cortex membranes.

Dennis I, Whalley BJ, Stephens GJ.

Br J Pharmacol. 2008 Jul;154(6):1349-58. doi: 10.1038/bjp.2008.190. Epub 2008 May 19.

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