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Items: 1 to 50 of 80

1.

Observation of high-temperature macromolecular confinement in lyophilised protein formulations using terahertz spectroscopy.

Shmool TA, Woodhams PJ, Leutzsch M, Stephens AD, Gaimann MU, Mantle MD, Kaminski Schierle GS, van der Walle CF, Zeitler JA.

Int J Pharm X. 2019 Jul 8;1:100022. doi: 10.1016/j.ijpx.2019.100022. eCollection 2019 Dec.

2.

Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation.

Stephens AD, Liu PZ, Kandula V, Chen H, Almassalha LM, Herman C, Backman V, O'Halloran T, Adam SA, Goldman RD, Banigan EJ, Marko JF.

Mol Biol Cell. 2019 Aug 1;30(17):2320-2330. doi: 10.1091/mbc.E19-05-0286.

3.

The role of water in amyloid aggregation kinetics.

Stephens AD, Kaminski Schierle GS.

Curr Opin Struct Biol. 2019 Oct;58:115-123. doi: 10.1016/j.sbi.2019.06.001. Epub 2019 Jul 10. Review.

PMID:
31299481
4.

Physicochemical mechanotransduction alters nuclear shape and mechanics via heterochromatin formation.

Stephens AD, Liu PZ, Kandula V, Chen H, Almassalha LM, Herman C, Backman V, O'Halloran T, Adam SA, Goldman RD, Banigan EJ, Marko JF.

Mol Biol Cell. 2019 Jun 19:mbcE19050286T. doi: 10.1091/mbc.E19-05-0286-T. [Epub ahead of print]

PMID:
31216230
5.

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans.

Huang C, Wagner-Valladolid S, Stephens AD, Jung R, Poudel C, Sinnige T, Lechler MC, Schlörit N, Lu M, Laine RF, Michel CH, Vendruscolo M, Kaminski CF, Kaminski Schierle GS, David DC.

Elife. 2019 May 3;8. pii: e43059. doi: 10.7554/eLife.43059.

6.

Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm.

Gladstein S, Almassalha LM, Cherkezyan L, Chandler JE, Eshein A, Eid A, Zhang D, Wu W, Bauer GM, Stephens AD, Morochnik S, Subramanian H, Marko JF, Ameer GA, Szleifer I, Backman V.

Nat Commun. 2019 Apr 10;10(1):1652. doi: 10.1038/s41467-019-09717-6.

7.

Chromatin's physical properties shape the nucleus and its functions.

Stephens AD, Banigan EJ, Marko JF.

Curr Opin Cell Biol. 2019 Jun;58:76-84. doi: 10.1016/j.ceb.2019.02.006. Epub 2019 Mar 16. Review.

PMID:
30889417
8.

Evaluation of the suitability of the World Health Organization International Reference Reagent for Hb A2 quantitation (89/666) for continued use.

De la Salle B, Stephens AD, Wild BJ, Harteveld CL, Hyde K.

Int J Lab Hematol. 2019 Apr;41(2):262-270. doi: 10.1111/ijlh.12966. Epub 2019 Jan 20.

PMID:
30663262
9.

Effects of altering histone posttranslational modifications on mitotic chromosome structure and mechanics.

Biggs R, Liu PZ, Stephens AD, Marko JF.

Mol Biol Cell. 2019 Mar 21;30(7):820-827. doi: 10.1091/mbc.E18-09-0592. Epub 2019 Jan 9.

10.

The Cellular Environment Affects Monomeric α-Synuclein Structure.

Stephens AD, Zacharopoulou M, Kaminski Schierle GS.

Trends Biochem Sci. 2019 May;44(5):453-466. doi: 10.1016/j.tibs.2018.11.005. Epub 2018 Dec 7. Review.

PMID:
30527975
11.

Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing.

Stephens AD, Nespovitaya N, Zacharopoulou M, Kaminski CF, Phillips JJ, Kaminski Schierle GS.

Anal Chem. 2018 Jun 5;90(11):6975-6983. doi: 10.1021/acs.analchem.8b01264. Epub 2018 May 22.

12.

C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction.

Lautenschläger J, Stephens AD, Fusco G, Ströhl F, Curry N, Zacharopoulou M, Michel CH, Laine R, Nespovitaya N, Fantham M, Pinotsi D, Zago W, Fraser P, Tandon A, St George-Hyslop P, Rees E, Phillips JJ, De Simone A, Kaminski CF, Schierle GSK.

Nat Commun. 2018 Feb 19;9(1):712. doi: 10.1038/s41467-018-03111-4.

13.

Phylogeographic diversity and mosaicism of the Helicobacter pylori tfs integrative and conjugative elements.

Delahay RM, Croxall NJ, Stephens AD.

Mob DNA. 2018 Jan 26;9:5. doi: 10.1186/s13100-018-0109-4. eCollection 2018.

14.

Separate roles for chromatin and lamins in nuclear mechanics.

Stephens AD, Banigan EJ, Marko JF.

Nucleus. 2018 Jan 1;9(1):119-124. doi: 10.1080/19491034.2017.1414118. Epub 2017 Dec 28.

15.

Chromatin histone modifications and rigidity affect nuclear morphology independent of lamins.

Stephens AD, Liu PZ, Banigan EJ, Almassalha LM, Backman V, Adam SA, Goldman RD, Marko JF.

Mol Biol Cell. 2018 Jan 15;29(2):220-233. doi: 10.1091/mbc.E17-06-0410. Epub 2017 Nov 15.

16.

Mechanics and Buckling of Biopolymeric Shells and Cell Nuclei.

Banigan EJ, Stephens AD, Marko JF.

Biophys J. 2017 Oct 17;113(8):1654-1663. doi: 10.1016/j.bpj.2017.08.034.

17.

Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein.

Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Schierle GSK, Vendruscolo M, Veglia G, Dobson CM, De Simone A.

Nat Commun. 2017 May 11;8:15667. doi: 10.1038/ncomms15667. No abstract available.

18.

Chromatin and lamin A determine two different mechanical response regimes of the cell nucleus.

Stephens AD, Banigan EJ, Adam SA, Goldman RD, Marko JF.

Mol Biol Cell. 2017 Jul 7;28(14):1984-1996. doi: 10.1091/mbc.E16-09-0653. Epub 2017 Jan 5.

19.

Structural basis of synaptic vesicle assembly promoted by α-synuclein.

Fusco G, Pape T, Stephens AD, Mahou P, Costa AR, Kaminski CF, Kaminski Schierle GS, Vendruscolo M, Veglia G, Dobson CM, De Simone A.

Nat Commun. 2016 Sep 19;7:12563. doi: 10.1038/ncomms12563.

20.

ICSH recommendations for assessing automated high-performance liquid chromatography and capillary electrophoresis equipment for the quantitation of HbA2.

Stephens AD, Colah R, Fucharoen S, Hoyer J, Keren D, McFarlane A, Perrett D, Wild BJ; International Council for Standardization in Haematology (ICSH).

Int J Lab Hematol. 2015 Oct;37(5):577-82. doi: 10.1111/ijlh.12413. Review.

21.
22.

Dyskerin, tRNA genes, and condensin tether pericentric chromatin to the spindle axis in mitosis.

Snider CE, Stephens AD, Kirkland JG, Hamdani O, Kamakaka RT, Bloom K.

J Cell Biol. 2014 Oct 27;207(2):189-99. doi: 10.1083/jcb.201405028. Epub 2014 Oct 20.

23.

ICSH: on board for new projects.

Zini G, Kern W, Brereton M, Stephens AD.

Int J Lab Hematol. 2014 Jun;36(3):306-12. doi: 10.1111/ijlh.12232. Review.

PMID:
24750677
24.

Individual pericentromeres display coordinated motion and stretching in the yeast spindle.

Stephens AD, Snider CE, Haase J, Haggerty RA, Vasquez PA, Forest MG, Bloom K.

J Cell Biol. 2013 Nov 11;203(3):407-16. doi: 10.1083/jcb.201307104. Epub 2013 Nov 4.

25.

The spatial segregation of pericentric cohesin and condensin in the mitotic spindle.

Stephens AD, Quammen CW, Chang B, Haase J, Taylor RM 2nd, Bloom K.

Mol Biol Cell. 2013 Dec;24(24):3909-19. doi: 10.1091/mbc.E13-06-0325. Epub 2013 Oct 23.

26.

Bending the rules: widefield microscopy and the Abbe limit of resolution.

Verdaasdonk JS, Stephens AD, Haase J, Bloom K.

J Cell Physiol. 2014 Feb;229(2):132-8. doi: 10.1002/jcp.24439. Review.

27.

Pericentric chromatin loops function as a nonlinear spring in mitotic force balance.

Stephens AD, Haggerty RA, Vasquez PA, Vicci L, Snider CE, Shi F, Quammen C, Mullins C, Haase J, Taylor RM 2nd, Verdaasdonk JS, Falvo MR, Jin Y, Forest MG, Bloom K.

J Cell Biol. 2013 Mar 18;200(6):757-72. doi: 10.1083/jcb.201208163.

28.

Haemoglobin A₂ analysis.

Stephens AD.

Int J Lab Hematol. 2013 Feb;35(1):116. doi: 10.1111/ijlh.12024. Epub 2012 Nov 14. No abstract available.

PMID:
23157610
29.

Tension-dependent nucleosome remodeling at the pericentromere in yeast.

Verdaasdonk JS, Gardner R, Stephens AD, Yeh E, Bloom K.

Mol Biol Cell. 2012 Jul;23(13):2560-70. doi: 10.1091/mbc.E11-07-0651. Epub 2012 May 16.

30.

Secondary erythrocytosis due to compound homozygosity, but not compound heterozygosity, for Hb Luton and α-thalassemia: a family study.

El-Sharkawi D, Fisher C, Khambadkone S, Stephens AD, Porter JB.

Hemoglobin. 2012;36(1):7-17. doi: 10.3109/03630269.2011.641134. Epub 2012 Jan 4.

PMID:
22217338
31.

ICSH recommendations for the measurement of haemoglobin A2.

Stephens AD, Angastiniotis M, Baysal E, Chan V, Fucharoen S, Giordano PC, Hoyer JD, Mosca A, Wild B; International Council for the Standardisation of Haematology (ICSH).

Int J Lab Hematol. 2012 Feb;34(1):1-13. doi: 10.1111/j.1751-553X.2011.01368.x. Epub 2011 Oct 5.

PMID:
21974826
32.

ICSH recommendations for the measurement of haemoglobin F.

Stephens AD, Angastiniotis M, Baysal E, Chan V, Davis B, Fucharoen S, Giordano PC, Hoyer JD, Mosca A, Wild B; International Council for The Standardisation of Haematology (ICSH).

Int J Lab Hematol. 2012 Feb;34(1):14-20. doi: 10.1111/j.1751-553X.2011.01367.x. Epub 2011 Sep 14.

PMID:
21914140
33.

Cohesin, condensin, and the intramolecular centromere loop together generate the mitotic chromatin spring.

Stephens AD, Haase J, Vicci L, Taylor RM 2nd, Bloom K.

J Cell Biol. 2011 Jun 27;193(7):1167-80. doi: 10.1083/jcb.201103138.

34.

Direct interaction of Gas11 with microtubules: implications for the dynein regulatory complex.

Bekker JM, Colantonio JR, Stephens AD, Clarke WT, King SJ, Hill KL, Crosbie RH.

Cell Motil Cytoskeleton. 2007 Jun;64(6):461-73.

PMID:
17366626
35.

Hb Bart's in cord blood: an accurate indicator of alpha-thalassemia.

Rugless MJ, Fisher CA, Stephens AD, Amos RJ, Mohammed T, Old JM.

Hemoglobin. 2006;30(1):57-62.

PMID:
16540417
36.

A microtubule-binding domain in dynactin increases dynein processivity by skating along microtubules.

Culver-Hanlon TL, Lex SA, Stephens AD, Quintyne NJ, King SJ.

Nat Cell Biol. 2006 Mar;8(3):264-70. Epub 2006 Feb 12.

PMID:
16474384
37.

Windy weather and low humidity are associated with an increased number of hospital admissions for acute pain and sickle cell disease in an urban environment with a maritime temperate climate.

Jones S, Duncan ER, Thomas N, Walters J, Dick MC, Height SE, Stephens AD, Thein SL, Rees DC.

Br J Haematol. 2005 Nov;131(4):530-3.

PMID:
16281945
38.

Myocardial biopsy and T2* magnetic resonance in heart failure due to thalassaemia.

Westwood MA, Sheppard MN, Awogbade M, Ellis G, Stephens AD, Pennell DJ.

Br J Haematol. 2005 Jan;128(1):2. No abstract available.

PMID:
15606544
39.
40.

Guidelines for the management of the acute painful crisis in sickle cell disease.

Rees DC, Olujohungbe AD, Parker NE, Stephens AD, Telfer P, Wright J; British Committee for Standards in Haematology General Haematology Task Force by the Sickle Cell Working Party.

Br J Haematol. 2003 Mar;120(5):744-52. No abstract available.

PMID:
12614204
41.

Safety monitoring of the coliseum technique for heated intraoperative intraperitoneal chemotherapy with mitomycin C.

Stuart OA, Stephens AD, Welch L, Sugarbaker PH.

Ann Surg Oncol. 2002 Mar;9(2):186-91.

PMID:
11888877
42.

Rapid identification of hemoglobin variants by electrospray ionization mass spectrometry.

Wild BJ, Green BN, Cooper EK, Lalloz MR, Erten S, Stephens AD, Layton DM.

Blood Cells Mol Dis. 2001 May-Jun;27(3):691-704.

PMID:
11482884
43.
44.

Hemodynamic and cardiac function parameters during heated intraoperative intraperitoneal chemotherapy using the open "coliseum technique".

Esquivel J, Angulo F, Bland RK, Stephens AD, Sugarbaker PH.

Ann Surg Oncol. 2000 May;7(4):296-300.

PMID:
10819370
45.

Morbidity and mortality analysis of 200 treatments with cytoreductive surgery and hyperthermic intraoperative intraperitoneal chemotherapy using the coliseum technique.

Stephens AD, Alderman R, Chang D, Edwards GD, Esquivel J, Sebbag G, Steves MA, Sugarbaker PH.

Ann Surg Oncol. 1999 Dec;6(8):790-6.

PMID:
10622509
46.

Heated intraoperative intraperitoneal mitomycin C and early postoperative intraperitoneal 5-fluorouracil: pharmacokinetic studies.

Jacquet P, Averbach A, Stephens AD, Stuart OA, Chang D, Sugarbaker PH.

Oncology. 1998 Mar-Apr;55(2):130-8.

PMID:
9499187
47.

The use of automated HPLC to detect and quantitate haemoglobins.

Wild BJ, Stephens AD.

Clin Lab Haematol. 1997 Sep;19(3):171-6.

PMID:
9352140
48.

Analysis of morbidity and mortality in 60 patients with peritoneal carcinomatosis treated by cytoreductive surgery and heated intraoperative intraperitoneal chemotherapy.

Jacquet P, Stephens AD, Averbach AM, Chang D, Ettinghausen SE, Dalton RR, Steves MA, Sugarbaker PH.

Cancer. 1996 Jun 15;77(12):2622-9.

PMID:
8640714
49.

Hyperthermic intraoperative intraperitoneal chemotherapy safety considerations.

White SK, Stephens AD, Sugarbaker PH.

AORN J. 1996 Apr;63(4):716-24.

PMID:
8660017
50.

Hyperthermic intraoperative intreperitoneal chemotherapy (HIIC) with mitomycin C.

Sugarbaker PH, Averbach AM, Jacquet P, Stuart OA, Stephens AD.

Surg Technol Int. 1996;5:245-9.

PMID:
15858747

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