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A journey from microenvironment to macroenvironment: the role of metaflammation and epigenetic changes in cardiorenal disease.

Kanbay M, Yerlikaya A, Sag AA, Ortiz A, Kuwabara M, Covic A, Wiecek A, Stenvinkel P, Afsar B.

Clin Kidney J. 2019 Sep 18;12(6):861-870. doi: 10.1093/ckj/sfz106. eCollection 2019 Dec.


Fruit and Vegetable Intake and Mortality in Adults undergoing Maintenance Hemodialysis.

Saglimbene VM, Wong G, Ruospo M, Palmer SC, Garcia-Larsen V, Natale P, Teixeira-Pinto A, Campbell KL, Carrero JJ, Stenvinkel P, Gargano L, Murgo AM, Johnson DW, Tonelli M, Gelfman R, Celia E, Ecder T, Bernat AG, Del Castillo D, Timofte D, Török M, Bednarek-Skublewska A, Duława J, Stroumza P, Hoischen S, Hansis M, Fabricius E, Felaco P, Wollheim C, Hegbrant J, Craig JC, Strippoli GFM.

Clin J Am Soc Nephrol. 2019 Feb 7;14(2):250-260. doi: 10.2215/CJN.08580718. Epub 2019 Jan 31.


Bone alkaline phosphatase: an important biomarker in chronic kidney disease - mineral and bone disorder.

Nizet A, Cavalier E, Stenvinkel P, Haarhaus M, Magnusson P.

Clin Chim Acta. 2019 Nov 14. pii: S0009-8981(19)32125-4. doi: 10.1016/j.cca.2019.11.012. [Epub ahead of print]


Bone mineral density at different sites and 5 years mortality in end-stage renal disease patients: A cohort study.

Iseri K, Qureshi AR, Dai L, Ripsweden J, Heimbürger O, Barany P, Bergström I, Stenvinkel P, Brismar TB, Lindholm B.

Bone. 2020 Jan;130:115075. doi: 10.1016/j.bone.2019.115075. Epub 2019 Oct 24.


Correction: Preeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study.

Khashan AS, Evans M, Kublickas M, McCarthy FP, Kenny LC, Stenvinkel P, Fitzgerald T, Kublickiene K.

PLoS Med. 2019 Oct 24;16(10):e1002977. doi: 10.1371/journal.pmed.1002977. eCollection 2019 Oct.


Biomimetics - Nature's roadmap to insights and solutions for burden of lifestyle diseases.

Stenvinkel P, Painer J, Johnson RJ, Natterson-Horowitz B.

J Intern Med. 2019 Oct 22. doi: 10.1111/joim.12982. [Epub ahead of print]


Fructose metabolism as a common evolutionary pathway of survival associated with climate change, food shortage and droughts.

Johnson RJ, Stenvinkel P, Andrews P, Sánchez-Lozada LG, Nakagawa T, Gaucher E, Andres-Hernando A, Rodriguez-Iturbe B, Jimenez CR, Garcia G, Kang DH, Tolan DR, Lanaspa MA.

J Intern Med. 2019 Oct 17. doi: 10.1111/joim.12993. [Epub ahead of print]


Fabry Disease: A New Model of Premature Ageing?

Kooman JP, Stenvinkel P, Shiels PG.

Nephron. 2019 Sep 27:1-4. doi: 10.1159/000503290. [Epub ahead of print] No abstract available.


Dietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysis.

Saglimbene VM, Wong G, Teixeira-Pinto A, Ruospo M, Garcia-Larsen V, Palmer SC, Natale P, Campbell K, Carrero JJ, Stenvinkel P, Gargano L, Murgo AM, Johnson DW, Tonelli M, Gelfman R, Celia E, Ecder T, Bernat AG, Del Castillo D, Timofte D, Török M, Bednarek-Skublewska A, Duława J, Stroumza P, Hansis M, Fabricius E, Felaco P, Wollheim C, Hegbrant J, Craig JC, Strippoli GFM; DIET-HD Investigators and Dieticians.

Am J Kidney Dis. 2019 Sep 9. pii: S0272-6386(19)30851-0. doi: 10.1053/j.ajkd.2019.05.028. [Epub ahead of print]


Associations of Chronic Inflammation, Insulin Resistance, and Severe Obesity With Mortality, Myocardial Infarction, Cancer, and Chronic Pulmonary Disease.

Wiebe N, Stenvinkel P, Tonelli M.

JAMA Netw Open. 2019 Aug 2;2(8):e1910456. doi: 10.1001/jamanetworkopen.2019.10456.


Reduced skeletal muscle expression of mitochondrial-derived peptides humanin and MOTS-C and Nrf2 in chronic kidney disease.

Liu C, Gidlund EK, Witasp A, Qureshi AR, Söderberg M, Thorell A, Nader GA, Barany P, Stenvinkel P, von Walden F.

Am J Physiol Renal Physiol. 2019 Nov 1;317(5):F1122-F1131. doi: 10.1152/ajprenal.00202.2019. Epub 2019 Aug 21.


Allostatic load and ageing: linking the microbiome and nutrition with age-related health.

Shiels PG, Buchanan S, Selman C, Stenvinkel P.

Biochem Soc Trans. 2019 Aug 30;47(4):1165-1172. doi: 10.1042/BST20190110. Epub 2019 Aug 15. Review.


Serum 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, is associated with mortality independent of inflammation in chronic kidney disease.

Dai L, Watanabe M, Qureshi AR, Mukai H, Machowska A, Heimbürger O, Barany P, Lindholm B, Stenvinkel P.

Eur J Intern Med. 2019 Oct;68:60-65. doi: 10.1016/j.ejim.2019.07.035. Epub 2019 Aug 9.


Long-lived animals with negligible senescence: clues for ageing research.

Stenvinkel P, Shiels PG.

Biochem Soc Trans. 2019 Aug 30;47(4):1157-1164. doi: 10.1042/BST20190105. Epub 2019 Jul 31. Review.


Preeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study.

Khashan AS, Evans M, Kublickas M, McCarthy FP, Kenny LC, Stenvinkel P, Fitzgerald T, Kublickiene K.

PLoS Med. 2019 Jul 30;16(7):e1002875. doi: 10.1371/journal.pmed.1002875. eCollection 2019 Jul. Erratum in: PLoS Med. 2019 Oct 24;16(10):e1002977.


Early Vascular Ageing and Cellular Senescence in Chronic Kidney Disease.

Dai L, Qureshi AR, Witasp A, Lindholm B, Stenvinkel P.

Comput Struct Biotechnol J. 2019 Jun 18;17:721-729. doi: 10.1016/j.csbj.2019.06.015. eCollection 2019. Review.


Understanding the role of the cytoprotective transcription factor nuclear factor erythroid 2-related factor 2-lessons from evolution, the animal kingdom and rare progeroid syndromes.

Stenvinkel P, Meyer CJ, Block GA, Chertow GM, Shiels PG.

Nephrol Dial Transplant. 2019 Jul 13. pii: gfz120. doi: 10.1093/ndt/gfz120. [Epub ahead of print]


Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease.

Carracedo M, Witasp A, Qureshi AR, Laguna-Fernandez A, Brismar T, Stenvinkel P, Bäck M.

J Intern Med. 2019 Oct;286(4):449-457. doi: 10.1111/joim.12940. Epub 2019 Jul 7.


Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy.

Aubert CE, Liabeuf S, Amouyal C, Kemel S, Lajat-Kiss F, Lacorte JM, Halbron M, Carlier A, Salem JE, Funck-Brentano C, Perisic Matic L, Witasp A, Stenvinkel P, Phan F, Massy ZA, Hartemann A, Bourron O.

Diabetol Metab Syndr. 2019 Apr 29;11:32. doi: 10.1186/s13098-019-0429-7. eCollection 2019.


Cranberries - potential benefits in patients with chronic kidney disease.

de Almeida Alvarenga L, Borges NA, Moreira LSG, Resende Teixeira KT, Carraro-Eduardo JC, Dai L, Stenvinkel P, Lindholm B, Mafra D.

Food Funct. 2019 Jun 19;10(6):3103-3112. doi: 10.1039/c9fo00375d. Review.


Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization.

Karlöf E, Seime T, Dias N, Lengquist M, Witasp A, Almqvist H, Kronqvist M, Gådin JR, Odeberg J, Maegdefessel L, Stenvinkel P, Matic LP, Hedin U.

Atherosclerosis. 2019 Sep;288:175-185. doi: 10.1016/j.atherosclerosis.2019.05.005. Epub 2019 May 11.


Nutritional status of older patients on hemodialysis: Which nutritional markers can best predict clinical outcomes?

Rodrigues J, Santin F, Brito FDSB, Lindholm B, Stenvinkel P, Avesani CM.

Nutrition. 2019 Sep;65:113-119. doi: 10.1016/j.nut.2019.03.002. Epub 2019 Mar 20.


Adverse pregnancy outcomes and long-term risk of maternal renal disease: a systematic review and meta-analysis protocol.

Barrett PM, McCarthy FP, Kublickiene K, Evans M, Cormican S, Judge C, Perry IJ, Kublickas M, Stenvinkel P, Khashan AS.

BMJ Open. 2019 May 5;9(5):e027180. doi: 10.1136/bmjopen-2018-027180.


Health-related quality of life as predictor of mortality in end-stage renal disease patients: an observational study.

Pei M, Aguiar R, Pagels AA, Heimbürger O, Stenvinkel P, Bárány P, Medin C, Jacobson SH, Hylander B, Lindholm B, Qureshi AR.

BMC Nephrol. 2019 Apr 29;20(1):144. doi: 10.1186/s12882-019-1318-x.


Association of changes in bone mineral parameters with mortality in haemodialysis patients: insights from the ARO cohort.

Lamina C, Kronenberg F, Stenvinkel P, Froissart M, Forer L, Schönherr S, Wheeler DC, Eckardt KU, Floege J.

Nephrol Dial Transplant. 2019 Apr 21. pii: gfz060. doi: 10.1093/ndt/gfz060. [Epub ahead of print]


Dietary Components That May Influence the Disturbed Gut Microbiota in Chronic Kidney Disease.

Mafra D, Borges N, Alvarenga L, Esgalhado M, Cardozo L, Lindholm B, Stenvinkel P.

Nutrients. 2019 Feb 27;11(3). pii: E496. doi: 10.3390/nu11030496. Review.


Methyl Donor Nutrients in Chronic Kidney Disease: Impact on the Epigenetic Landscape.

Mafra D, Esgalhado M, Borges NA, Cardozo LFMF, Stockler-Pinto MB, Craven H, Buchanan SJ, Lindholm B, Stenvinkel P, Shiels PG.

J Nutr. 2019 Mar 1;149(3):372-380. doi: 10.1093/jn/nxy289.


Differences in association of lower bone mineral density with higher coronary calcification in female and male end-stage renal disease patients.

Chen Z, Qureshi AR, Brismar TB, Ripsweden J, Haarhaus M, Barany P, Heimburger O, Lindholm B, Stenvinkel P.

BMC Nephrol. 2019 Feb 18;20(1):59. doi: 10.1186/s12882-019-1235-z.


Senescent Cells in Early Vascular Ageing and Bone Disease of Chronic Kidney Disease-A Novel Target for Treatment.

Hobson S, Arefin S, Kublickiene K, Shiels PG, Stenvinkel P.

Toxins (Basel). 2019 Feb 1;11(2). pii: E82. doi: 10.3390/toxins11020082. Review.


A distinct bone phenotype in ADPKD patients with end-stage renal disease.

Evenepoel P, Claes K, Cavalier E, Meijers B, Stenvinkel P, Behets G, Jankowska M, D'Haese P, Bammens B.

Kidney Int. 2019 Feb;95(2):412-419. doi: 10.1016/j.kint.2018.09.018.


MicroRNAs in AKI and Kidney Transplantation.

Ledeganck KJ, Gielis EM, Abramowicz D, Stenvinkel P, Shiels PG, Van Craenenbroeck AH.

Clin J Am Soc Nephrol. 2019 Mar 7;14(3):454-468. doi: 10.2215/CJN.08020718. Epub 2019 Jan 2. Review.


The G-protein coupled receptor ChemR23 determines smooth muscle cell phenotypic switching to enhance high phosphate-induced vascular calcification.

Carracedo M, Artiach G, Witasp A, Clària J, Carlström M, Laguna-Fernandez A, Stenvinkel P, Bäck M.

Cardiovasc Res. 2019 Aug 1;115(10):1557-1566. doi: 10.1093/cvr/cvy316.


Inverse J-shaped relation between coronary arterial calcium density and mortality in advanced chronic kidney disease.

Mukai H, Dai L, Chen Z, Lindholm B, Ripsweden J, Brismar TB, Heimbürger O, Barany P, Qureshi AR, Söderberg M, Bäck M, Stenvinkel P.

Nephrol Dial Transplant. 2018 Dec 7. doi: 10.1093/ndt/gfy352. [Epub ahead of print]


Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease.

Feldreich T, Nowak C, Fall T, Carlsson AC, Carrero JJ, Ripsweden J, Qureshi AR, Heimbürger O, Barany P, Stenvinkel P, Vuilleumier N, Kalra PA, Green D, Ärnlöv J.

J Nephrol. 2019 Feb;32(1):111-119. doi: 10.1007/s40620-018-0556-5. Epub 2018 Nov 29.


Mitochondrial dysfunction and gut microbiota imbalance: An intriguing relationship in chronic kidney disease.

Mafra D, Borges NA, Lindholm B, Stenvinkel P.

Mitochondrion. 2019 Jul;47:206-209. doi: 10.1016/j.mito.2018.11.006. Epub 2018 Nov 5. No abstract available.


Association of Serum Sclerostin with Bone Sclerostin in Chronic Kidney Disease is Lost in Glucocorticoid Treated Patients.

Boltenstål H, Qureshi AR, Behets GJ, Lindholm B, Stenvinkel P, D'Haese PC, Haarhaus M.

Calcif Tissue Int. 2019 Feb;104(2):214-223. doi: 10.1007/s00223-018-0491-4. Epub 2018 Nov 7.


Effects of acute fructose loading on levels of serum uric acid-a pilot study.

Olofsson C, Anderstam B, Bragfors-Helin AC, Eriksson M, Qureshi AR, Lindholm B, Hilding A, Wiczkowski W, Orsini N, Stenvinkel P, Rajamand Ekberg N.

Eur J Clin Invest. 2019 Jan;49(1):e13040. doi: 10.1111/eci.13040. Epub 2018 Nov 16.


Chronic inflammation in end-stage renal disease and dialysis.

Cobo G, Lindholm B, Stenvinkel P.

Nephrol Dial Transplant. 2018 Oct 1;33(suppl_3):iii35-iii40. doi: 10.1093/ndt/gfy175. Review.


Serum Glutaredoxin Activity as a Marker of Oxidative Stress in Chronic Kidney Disease: A Pilot Study.

Levin A, Nair D, Qureshi AR, Bárány P, Heimburger O, Anderstam B, Stenvinkel P, Bruchfeld A, Ungerstedt JS.

Nephron. 2018;140(4):249-256. doi: 10.1159/000492500. Epub 2018 Sep 25.


Bioactive food and exercise in chronic kidney disease: Targeting the mitochondria.

Mafra D, Gidlund EK, Borges NA, Magliano DC, Lindholm B, Stenvinkel P, von Walden F.

Eur J Clin Invest. 2018 Nov;48(11):e13020. doi: 10.1111/eci.13020. Epub 2018 Sep 16. Review.


Hypoalbuminemia: a price worth paying for improved dialytic removal of middle-molecular-weight uremic toxins?

Ward RA, Beck W, Bernardo AA, Alves FC, Stenvinkel P, Lindholm B.

Nephrol Dial Transplant. 2019 Jun 1;34(6):901-907. doi: 10.1093/ndt/gfy236.


Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients.

Molanaei H, Qureshi AR, Heimbürger O, Lindholm B, Diczfalusy U, Anderstam B, Bertilsson L, Stenvinkel P.

BMC Pharmacol Toxicol. 2018 Jun 25;19(1):33. doi: 10.1186/s40360-018-0221-6.


Serum albumin, inflammation, and nutrition in end-stage renal disease: C-reactive protein is needed for optimal assessment.

Mukai H, Villafuerte H, Qureshi AR, Lindholm B, Stenvinkel P.

Semin Dial. 2018 Sep;31(5):435-439. doi: 10.1111/sdi.12731. Epub 2018 Jun 21.


The value of the Brazilian açai fruit as a therapeutic nutritional strategy for chronic kidney disease patients.

Martins ICVS, Borges NA, Stenvinkel P, Lindholm B, Rogez H, Pinheiro MCN, Nascimento JLM, Mafra D.

Int Urol Nephrol. 2018 Dec;50(12):2207-2220. doi: 10.1007/s11255-018-1912-z. Epub 2018 Jun 18. Review.


Pregnancy-associated plasma protein A and mortality in haemodialysis.

Nilsson E, Rudholm T, Stenvinkel P, Ärnlöv J.

Eur J Clin Invest. 2018 Aug;48(8):e12959. doi: 10.1111/eci.12959. Epub 2018 Jun 7.


Restrictive lung disorder is common in patients with kidney failure and associates with protein-energy wasting, inflammation and cardiovascular disease.

Mukai H, Ming P, Lindholm B, Heimbürger O, Barany P, Anderstam B, Stenvinkel P, Qureshi AR.

PLoS One. 2018 Apr 27;13(4):e0195585. doi: 10.1371/journal.pone.0195585. eCollection 2018.


The Association of Mediterranean and DASH Diets with Mortality in Adults on Hemodialysis: The DIET-HD Multinational Cohort Study.

Saglimbene VM, Wong G, Craig JC, Ruospo M, Palmer SC, Campbell K, Garcia-Larsen V, Natale P, Teixeira-Pinto A, Carrero JJ, Stenvinkel P, Gargano L, Murgo AM, Johnson DW, Tonelli M, Gelfman R, Celia E, Ecder T, Bernat AG, Del Castillo D, Timofte D, Török M, Bednarek-Skublewska A, Duława J, Stroumza P, Hoischen S, Hansis M, Fabricius E, Felaco P, Wollheim C, Hegbrant J, Strippoli GFM.

J Am Soc Nephrol. 2018 Jun;29(6):1741-1751. doi: 10.1681/ASN.2018010008. Epub 2018 Apr 25.


Effects of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Levels in Hemodialysis Patients: a Pilot Study.

Borges NA, Stenvinkel P, Bergman P, Qureshi AR, Lindholm B, Moraes C, Stockler-Pinto MB, Mafra D.

Probiotics Antimicrob Proteins. 2019 Jun;11(2):648-654. doi: 10.1007/s12602-018-9411-1.


Lung Dysfunction and Mortality in Patients with Chronic Kidney Disease.

Mukai H, Ming P, Lindholm B, Heimbürger O, Barany P, Stenvinkel P, Qureshi AR.

Kidney Blood Press Res. 2018;43(2):522-535. doi: 10.1159/000488699. Epub 2018 Mar 29.


The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages.

Missailidis C, Neogi U, Stenvinkel P, Trøseid M, Nowak P, Bergman P.

AIDS. 2018 Jul 31;32(12):1589-1598. doi: 10.1097/QAD.0000000000001813.


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