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Items: 1 to 50 of 611

1.

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its Function.

Srinivasan S, Stephens C, Wilson E, Panchadsaram J, DeVoss K, Koistinen H, Stenman UH, Brook MN, Buckle AM, Klein RJ, Lilja H, Clements J, Batra J; Practical Consortium.

Clin Chem. 2019 Jan;65(1):e1-e9. doi: 10.1373/clinchem.2018.295790. Epub 2018 Dec 11.

PMID:
30538125
2.

Risk Prediction of Prostate Cancer with Single Nucleotide Polymorphisms (SNPs) and Prostate-Specific Antigen (PSA).

Chen SL, Fann JC, Sipeky C, Yang TK, Chiu SY, Yen AM, Laitinen V, Tammela TL, Stenman UH, Auvinen A, Schleutker J, Chen HH.

J Urol. 2018 Oct 23. pii: S0022-5347(18)44024-4. doi: 10.1016/j.juro.2018.10.015. [Epub ahead of print]

PMID:
30366021
3.

The Number of Screening Cycles Needed to Reduce Prostate Cancer Mortality in the Finnish Section of the European Randomized Study of Prostate Cancer (ERSPC).

Pakarainen T, Nevalainen J, Talala K, Taari K, Raitanen J, Kujala P, Stenman UH, Tammela TLJ, Auvinen A.

Clin Cancer Res. 2018 Oct 15. doi: 10.1158/1078-0432.CCR-18-1807. [Epub ahead of print]

PMID:
30322875
4.

Hyperglycosylated hCG activates LH/hCG-receptor with lower activity than hCG.

Koistinen H, Koel M, Peters M, Rinken A, Lundin K, Tuuri T, Tapanainen JS, Alfthan H, Salumets A, Stenman UH, Lavogina D.

Mol Cell Endocrinol. 2019 Jan 5;479:103-109. doi: 10.1016/j.mce.2018.09.006. Epub 2018 Oct 2.

5.

Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models.

Murtoniemi K, Villa PM, Matomäki J, Keikkala E, Vuorela P, Hämäläinen E, Kajantie E, Pesonen AK, Räikkönen K, Taipale P, Stenman UH, Laivuori H.

BMC Pregnancy Childbirth. 2018 Jul 3;18(1):279. doi: 10.1186/s12884-018-1908-9.

6.

Serum MMP-8 and TIMP-1 predict prognosis in colorectal cancer.

Böckelman C, Beilmann-Lehtonen I, Kaprio T, Koskensalo S, Tervahartiala T, Mustonen H, Stenman UH, Sorsa T, Haglund C.

BMC Cancer. 2018 Jun 22;18(1):679. doi: 10.1186/s12885-018-4589-x.

7.

Specificity profiling of human trypsin-isoenzymes.

Schilling O, Biniossek ML, Mayer B, Elsässer B, Brandstetter H, Goettig P, Stenman UH, Koistinen H.

Biol Chem. 2018 Sep 25;399(9):997-1007. doi: 10.1515/hsz-2018-0107.

PMID:
29883318
8.

Postoperative CEA is a better prognostic marker than CA19-9, hCGβ or TATI after resection of colorectal liver metastases.

Peltonen R, Österlund P, Lempinen M, Nordin A, Stenman UH, Isoniemi H.

Tumour Biol. 2018 Jan;40(1):1010428317752944. doi: 10.1177/1010428317752944.

PMID:
29378497
9.

An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants.

Ravela S, Valmu L, Domanskyy M, Koistinen H, Kylänpää L, Lindström O, Stenman J, Hämäläinen E, Stenman UH, Itkonen O.

Anal Bioanal Chem. 2018 Feb;410(6):1679-1688. doi: 10.1007/s00216-017-0803-y. Epub 2018 Jan 9.

PMID:
29318362
10.

Circulating sex hormones in relation to anthropometric, sociodemographic and behavioural factors in an international dataset of 12,300 men.

Watts EL, Appleby PN, Albanes D, Black A, Chan JM, Chen C, Cirillo PM, Cohn BA, Cook MB, Donovan JL, Ferrucci L, Garland CF, Giles GG, Goodman PJ, Habel LA, Haiman CA, Holly JMP, Hoover RN, Kaaks R, Knekt P, Kolonel LN, Kubo T, Le Marchand L, Luostarinen T, MacInnis RJ, Mäenpää HO, Männistö S, Metter EJ, Milne RL, Nomura AMY, Oliver SE, Parsons JK, Peeters PH, Platz EA, Riboli E, Ricceri F, Rinaldi S, Rissanen H, Sawada N, Schaefer CA, Schenk JM, Stanczyk FZ, Stampfer M, Stattin P, Stenman UH, Tjønneland A, Trichopoulou A, Thompson IM, Tsugane S, Vatten L, Whittemore AS, Ziegler RG, Allen NE, Key TJ, Travis RC.

PLoS One. 2017 Dec 27;12(12):e0187741. doi: 10.1371/journal.pone.0187741. eCollection 2017.

11.

Portable device for generation of ultra-pure water vapor feeds.

Velin P, Stenman U, Skoglundh M, Carlsson PA.

Rev Sci Instrum. 2017 Nov;88(11):115102. doi: 10.1063/1.4994245.

PMID:
29195377
12.

MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E-mutant colorectal adenocarcinoma.

Räsänen K, Dang KX, Mustonen H, Ho TH, Lintula S, Koistinen H, Stenman UH, Haglund C, Stenman J.

Mol Oncol. 2018 Feb;12(2):224-238. doi: 10.1002/1878-0261.12160. Epub 2017 Dec 27.

13.

A Four-kallikrein Panel and β-Microseminoprotein in Predicting High-grade Prostate Cancer on Biopsy: An Independent Replication from the Finnish Section of the European Randomized Study of Screening for Prostate Cancer.

Assel M, Sjöblom L, Murtola TJ, Talala K, Kujala P, Stenman UH, Taari K, Auvinen A, Vickers A, Visakorpi T, Tammela TL, Lilja H.

Eur Urol Focus. 2017 Nov 11. pii: S2405-4569(17)30258-4. doi: 10.1016/j.euf.2017.11.002. [Epub ahead of print]

PMID:
29137895
14.

An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells.

Adibi JJ, Zhao Y, Zhan LV, Kapidzic M, Larocque N, Koistinen H, Huhtaniemi IT, Stenman UH.

Environ Health Perspect. 2017 Oct 31;125(10):107010. doi: 10.1289/EHP1539.

15.

No Tissue Expression of KRAS or BRAF Mutations in 61 Adult Patients Treated for Esophageal Atresia in Early Childhood.

Dang KX, Ho T, Sistonen S, Koivusalo A, Pakarinen M, Rintala R, Stenman UH, Orpana A, Stenman J.

Eur J Pediatr Surg. 2018 Oct;28(5):413-419. doi: 10.1055/s-0037-1605346. Epub 2017 Sep 5.

PMID:
28873491
16.

Desmosterol accumulation in users of amiodarone.

Simonen P, Lehtonen J, Lampi AM, Piironen V, Stenman UH, Kupari M, Gylling H.

J Intern Med. 2018 Jan;283(1):93-101. doi: 10.1111/joim.12682. Epub 2017 Sep 21.

PMID:
28861933
17.

Determining the mechanisms of dietary turnip rapeseed oil on cholesterol metabolism in men with metabolic syndrome.

Saarinen HJ, Sittiwet C, Simonen P, Nissinen MJ, Stenman UH, Gylling H, Palomäki A.

J Investig Med. 2018 Jan;66(1):11-16. doi: 10.1136/jim-2017-000495. Epub 2017 Aug 11.

18.

Gender has to be taken into account in diagnosing adult growth hormone deficiency by the GHRH plus arginine test.

Markkanen HM, Pekkarinen T, Hämäläinen E, Välimäki MJ, Alfthan H, Stenman UH.

Growth Horm IGF Res. 2017 Aug;35:52-56. doi: 10.1016/j.ghir.2017.07.002. Epub 2017 Jul 18.

PMID:
28755537
19.

Outcomes of Prostate-specific Antigen-based Prostate Cancer Screening Among Men Using Nonsteroidal Anti-inflammatory Drugs.

Murtola TJ, Vettenranta AM, Talala K, Taari K, Stenman UH, Tammela TLJ, Auvinen A.

Eur Urol Focus. 2018 Dec;4(6):851-857. doi: 10.1016/j.euf.2017.03.005. Epub 2017 Mar 24.

PMID:
28753870
20.

Optimizing bone morphogenic protein 4-mediated human embryonic stem cell differentiation into trophoblast-like cells using fibroblast growth factor 2 and transforming growth factor-β/activin/nodal signalling inhibition.

Koel M, Võsa U, Krjutškov K, Einarsdottir E, Kere J, Tapanainen J, Katayama S, Ingerpuu S, Jaks V, Stenman UH, Lundin K, Tuuri T, Salumets A.

Reprod Biomed Online. 2017 Sep;35(3):253-263. doi: 10.1016/j.rbmo.2017.06.003. Epub 2017 Jun 12.

PMID:
28647356
21.

Outcomes of Prostate Cancer Screening by 5α-Reductase Inhibitor Use.

Murtola TJ, Virkku A, Talala K, Stenman UH, Taari K, Tammela TLJ, Auvinen A.

J Urol. 2017 Aug;198(2):305-309. doi: 10.1016/j.juro.2017.02.069. Epub 2017 Feb 16.

PMID:
28216328
22.

What explains the differences between centres in the European screening trial? A simulation study.

Nevalainen J, Stenman UH, Tammela TL, Roobol M, Carlsson S, Talala K, Schröder FH, Auvinen A.

Cancer Epidemiol. 2017 Feb;46:14-19. doi: 10.1016/j.canep.2016.11.005. Epub 2016 Nov 24.

23.

First trimester serum placental growth factor and hyperglycosylated human chorionic gonadotropin are associated with pre-eclampsia: a case control study.

Keikkala E, Koskinen S, Vuorela P, Laivuori H, Romppanen J, Heinonen S, Stenman UH.

BMC Pregnancy Childbirth. 2016 Nov 25;16(1):378.

24.

Systemic Inflammatory Response and Elevated Tumour Markers Predict Worse Survival in Resectable Pancreatic Ductal Adenocarcinoma.

Salmiheimo A, Mustonen H, Stenman UH, Puolakkainen P, Kemppainen E, Seppänen H, Haglund C.

PLoS One. 2016 Sep 15;11(9):e0163064. doi: 10.1371/journal.pone.0163064. eCollection 2016.

25.

Design-corrected variation by centre in mortality reduction in the ERSPC randomised prostate cancer screening trial.

Hakama M, Moss SM, Stenman UH, Roobol MJ, Zappa M, Carlsson S, Randazzo M, Nelen V, Hugosson J.

J Med Screen. 2017 Jun;24(2):98-103. doi: 10.1177/0969141316652174. Epub 2016 Aug 9.

26.

Virtual Screening of Small Drug-Like Compounds Stimulating the Enzymatic Activity of Kallikrein-Related Peptidase 3 (KLK3).

Ylikangas H, Mattsson JM, Stenman UH, Koistinen H, Poso A, Lahtela-Kakkonen M.

ChemMedChem. 2016 Sep 20;11(18):2043-9. doi: 10.1002/cmdc.201600181. Epub 2016 Jul 28.

PMID:
27465435
27.

Development of molecules stimulating the activity of KLK3 - an update.

Koistinen H, Wallén E, Ylikangas H, Meinander K, Lahtela-Kakkonen M, Närvänen A, Stenman UH.

Biol Chem. 2016 Dec 1;397(12):1229-1235. doi: 10.1515/hsz-2016-0189. Review.

PMID:
27383882
28.

Characterizing urinary hCGβcf patterns during pregnancy.

Nerenz RD, Yarbrough ML, Stenman UH, Gronowski AM.

Clin Biochem. 2016 Jul;49(10-11):777-81. doi: 10.1016/j.clinbiochem.2016.04.006. Epub 2016 Apr 14.

PMID:
27087510
29.

First Morning Voided Urinary Gonadotropin Measurements as an Alternative to the GnRH Test.

Demir A, Voutilainen R, Stenman UH, Dunkel L, Albertsson-Wikland K, Norjavaara E.

Horm Res Paediatr. 2016;85(5):301-8. doi: 10.1159/000440955. Epub 2016 Mar 25.

30.

Longitudinal biobanks-based study on the joint effects of infections, nutrition and hormones on risk of prostate cancer.

Lumme S, Tenkanen L, Langseth H, Gislefoss R, Hakama M, Stattin P, Hallmans G, Adlercreutz H, Saikku P, Stenman UH, Tuohimaa P, Luostarinen T, Dillner J.

Acta Oncol. 2016 Jul;55(7):839-45. doi: 10.3109/0284186X.2016.1139178. Epub 2016 Feb 15.

PMID:
26878091
31.

Interleukin-6 increases expression of serine protease inhibitor Kazal type 1 through STAT3 in colorectal adenocarcinoma.

Räsänen K, Lehtinen E, Nokelainen K, Kuopio T, Hautala L, Itkonen O, Stenman UH, Koistinen H.

Mol Carcinog. 2016 Dec;55(12):2010-2023. doi: 10.1002/mc.22447. Epub 2015 Dec 14.

PMID:
26663388
32.

Emerging Roles of SPINK1 in Cancer.

Räsänen K, Itkonen O, Koistinen H, Stenman UH.

Clin Chem. 2016 Mar;62(3):449-57. doi: 10.1373/clinchem.2015.241513. Epub 2015 Dec 11. Review.

33.

Absence of TGF-β Receptor Activation by Highly Purified hCG Preparations.

Koistinen H, Hautala L, Koli K, Stenman UH.

Mol Endocrinol. 2015 Dec;29(12):1787-91. doi: 10.1210/me.2015-1187. Epub 2015 Oct 23.

34.

Biomarker development, from bench to bedside.

Stenman UH.

Crit Rev Clin Lab Sci. 2016;53(2):69-86. doi: 10.3109/10408363.2015.1075468. Epub 2015 Aug 18. Review. Erratum in: Crit Rev Clin Lab Sci. 2016;53(2):i.

PMID:
26287282
35.

Use of non-steroidal anti-inflammatory drugs and prostate cancer survival in the Finnish prostate cancer screening trial.

Veitonmäki T, Murtola TJ, Määttänen L, Taari K, Stenman UH, Tammela TL, Auvinen A.

Prostate. 2015 Sep;75(13):1394-402. doi: 10.1002/pros.23020. Epub 2015 Jun 12.

PMID:
26073992
36.

Determination of steroid hormone concentrations.

Stenman UH.

Scand J Clin Lab Invest. 2015 Jul;75(4):289-90. doi: 10.3109/00365513.2015.1016102. No abstract available.

PMID:
25919020
38.

Polymorphisms of Genes Involved in Glucose and Energy Metabolic Pathways and Prostate Cancer: Interplay with Metformin.

Murtola TJ, Wahlfors T, Haring A, Taari K, Stenman UH, Tammela TL; PRACTICAL Consortium, Schleutker J, Auvinen A.

Eur Urol. 2015 Dec;68(6):1089-97. doi: 10.1016/j.eururo.2015.03.026. Epub 2015 Mar 26.

PMID:
25819720
39.

Associations between oral health and risk of dementia in a 37-year follow-up study: the prospective population study of women in Gothenburg.

Stewart R, Stenman U, Hakeberg M, Hägglin C, Gustafson D, Skoog I.

J Am Geriatr Soc. 2015 Jan;63(1):100-5. doi: 10.1111/jgs.13194.

PMID:
25597561
40.

Extendable blocking probe in reverse transcription for analysis of RNA variants with superior selectivity.

Ho TH, Dang KX, Lintula S, Hotakainen K, Feng L, Olkkonen VM, Verschuren EW, Tenkanen T, Haglund C, Kolho KL, Stenman UH, Stenman J.

Nucleic Acids Res. 2015 Jan;43(1):e4. doi: 10.1093/nar/gku1048. Epub 2014 Nov 5.

41.

The Finnish prostate cancer screening trial: analyses on the screening failures.

Kilpeläinen TP, Tammela TL, Malila N, Hakama M, Santti H, Määttänen L, Stenman UH, Kujala P, Auvinen A.

Int J Cancer. 2015 May 15;136(10):2437-43. doi: 10.1002/ijc.29300. Epub 2014 Nov 10.

42.

Proteolytic activity of prostate-specific antigen (PSA) towards protein substrates and effect of peptides stimulating PSA activity.

Mattsson JM, Ravela S, Hekim C, Jonsson M, Malm J, Närvänen A, Stenman UH, Koistinen H.

PLoS One. 2014 Sep 19;9(9):e107819. doi: 10.1371/journal.pone.0107819. eCollection 2014.

43.

Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up.

Schröder FH, Hugosson J, Roobol MJ, Tammela TL, Zappa M, Nelen V, Kwiatkowski M, Lujan M, Määttänen L, Lilja H, Denis LJ, Recker F, Paez A, Bangma CH, Carlsson S, Puliti D, Villers A, Rebillard X, Hakama M, Stenman UH, Kujala P, Taari K, Aus G, Huber A, van der Kwast TH, van Schaik RH, de Koning HJ, Moss SM, Auvinen A; ERSPC Investigators.

Lancet. 2014 Dec 6;384(9959):2027-35. doi: 10.1016/S0140-6736(14)60525-0. Epub 2014 Aug 6.

44.

Prostate cancer risk and nonsteroidal antiinflammatory drug use in the Finnish prostate cancer screening trial.

Veitonmäki T, Murtola TJ, Määttänen L, Taari K, Stenman UH, Tammela TL, Auvinen A.

Br J Cancer. 2014 Sep 23;111(7):1421-31. doi: 10.1038/bjc.2014.381. Epub 2014 Jul 10.

45.

Frontal electroencephalogram variables are associated with the outcome and stage of hepatic encephalopathy in acute liver failure.

Stewart J, Särkelä M, Koivusalo AM, Wennervirta J, Salmi T, Isoniemi H, Stenman UH, Viertiö-Oja H, Lapinlampi P, Lindgren L, Salminen US, Vakkuri A.

Liver Transpl. 2014 Oct;20(10):1256-65. doi: 10.1002/lt.23944. Epub 2014 Sep 15.

46.

Replacement of the Disulfide Bridge in a KLK3-Stimulating Peptide Using Orthogonally Protected Building Blocks.

Meinander K, Pakkala M, Weisell J, Stenman UH, Koistinen H, Närvänen A, Wallén EA.

ACS Med Chem Lett. 2013 Dec 16;5(2):162-5. doi: 10.1021/ml400419g. eCollection 2014 Feb 13.

47.

TATI as a biomarker.

Itkonen O, Stenman UH.

Clin Chim Acta. 2014 Apr 20;431:260-9. doi: 10.1016/j.cca.2014.02.014. Epub 2014 Feb 26. Review.

PMID:
24583226
48.

Expression of human chorionic gonadotropin in testicular germ cell tumors.

Lempiäinen A, Sankila A, Hotakainen K, Haglund C, Blomqvist C, Stenman UH.

Urol Oncol. 2014 Jul;32(5):727-34. doi: 10.1016/j.urolonc.2013.11.007. Epub 2014 Feb 4.

PMID:
24502963
49.

Serum hyperglycosylated human chorionic gonadotrophin at 14-17 weeks of gestation does not predict preeclampsia.

Keikkala E, Ranta JK, Vuorela P, Leinonen R, Laivuori H, Väisänen S, Marttala J, Romppanen J, Pulkki K, Stenman UH, Heinonen S.

Prenat Diagn. 2014 Jul;34(7):699-705. doi: 10.1002/pd.4335. Epub 2014 Feb 17.

PMID:
24464955
50.

Standardization of hormone determinations.

Stenman UH.

Best Pract Res Clin Endocrinol Metab. 2013 Dec;27(6):823-30. doi: 10.1016/j.beem.2013.10.007. Epub 2013 Oct 25. Review.

PMID:
24275193

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