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Items: 41


Adipose cell size changes are associated with a drastic actin remodeling.

Hansson B, Morén B, Fryklund C, Vliex L, Wasserstrom S, Albinsson S, Berger K, Stenkula KG.

Sci Rep. 2019 Sep 10;9(1):12941. doi: 10.1038/s41598-019-49418-0.


ApoAI-derived peptide increases glucose tolerance and prevents formation of atherosclerosis in mice.

Edmunds SJ, Liébana-García R, Nilsson O, Domingo-Espín J, Grönberg C, Stenkula KG, Lagerstedt JO.

Diabetologia. 2019 Jul;62(7):1257-1267. doi: 10.1007/s00125-019-4877-2. Epub 2019 May 8.


EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes.

Morén B, Hansson B, Negoita F, Fryklund C, Lundmark R, Göransson O, Stenkula KG.

Mol Biol Cell. 2019 May 1;30(10):1147-1159. doi: 10.1091/mbc.E18-10-0680. Epub 2019 Feb 27.


Insulin induces Thr484 phosphorylation and stabilization of SIK2 in adipocytes.

Säll J, Negoita F, Hansson B, Kopietz F, Linder W, Pettersson AML, Ekelund M, Laurencikiene J, Degerman E, Stenkula KG, Göransson O.

Cell Signal. 2019 Mar;55:73-80. doi: 10.1016/j.cellsig.2018.12.011. Epub 2018 Dec 23.


PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes.

Negoita F, Blomdahl J, Wasserstrom S, Winberg ME, Osmark P, Larsson S, Stenkula KG, Ekstedt M, Kechagias S, Holm C, Jones HA.

J Cell Biochem. 2019 Jan;120(1):343-356. doi: 10.1002/jcb.27378. Epub 2018 Sep 1.


Adipose cell size: importance in health and disease.

Stenkula KG, Erlanson-Albertsson C.

Am J Physiol Regul Integr Comp Physiol. 2018 Aug 1;315(2):R284-R295. doi: 10.1152/ajpregu.00257.2017. Epub 2018 Apr 11. Review.


MicroRNA-dependent regulation of KLF4 by glucose in vascular smooth muscle.

Hien TT, Garcia-Vaz E, Stenkula KG, Sjögren J, Nilsson J, Gomez MF, Albinsson S.

J Cell Physiol. 2018 Sep;233(9):7195-7205. doi: 10.1002/jcp.26549. Epub 2018 Mar 25.


N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism.

Ström K, Morales-Alamo D, Ottosson F, Edlund A, Hjort L, Jörgensen SW, Almgren P, Zhou Y, Martin-Rincon M, Ekman C, Pérez-López A, Ekström O, Perez-Suarez I, Mattiasson M, de Pablos-Velasco P, Oskolkov N, Ahlqvist E, Wierup N, Eliasson L, Vaag A, Groop L, Stenkula KG, Fernandez C, Calbet JAL, Holmberg HC, Hansson O.

Sci Rep. 2018 Feb 14;8(1):3016. doi: 10.1038/s41598-018-21099-1.


Intact glucose uptake despite deteriorating signaling in adipocytes with high-fat feeding.

Hansson B, Wasserstrom S, Morén B, Periwal V, Vikman P, Cushman SW, Göransson O, Storm P, Stenkula KG.

J Mol Endocrinol. 2018 Apr;60(3):199-211. doi: 10.1530/JME-17-0195. Epub 2018 Jan 16.


Total Internal Reflection Fluorescence Microscopy to Study GLUT4 Trafficking.

Wasserstrom S, Morén B, Stenkula KG.

Methods Mol Biol. 2018;1713:151-159. doi: 10.1007/978-1-4939-7507-5_12.


Similar regulatory mechanisms of caveolins and cavins by myocardin family coactivators in arterial and bladder smooth muscle.

Zhu B, Rippe C, Thi Hien T, Zeng J, Albinsson S, Stenkula KG, Uvelius B, Swärd K.

PLoS One. 2017 May 25;12(5):e0176759. doi: 10.1371/journal.pone.0176759. eCollection 2017.


A systems biology analysis connects insulin receptor signaling with glucose transporter translocation in rat adipocytes.

Bergqvist N, Nyman E, Cedersund G, Stenkula KG.

J Biol Chem. 2017 Jul 7;292(27):11206-11217. doi: 10.1074/jbc.M117.787515. Epub 2017 May 11.


Exercise differentially affects metabolic functions and white adipose tissue in female letrozole- and dihydrotestosterone-induced mouse models of polycystic ovary syndrome.

Marcondes RR, Maliqueo M, Fornes R, Benrick A, Hu M, Ivarsson N, Carlström M, Cushman SW, Stenkula KG, Maciel GAR, Stener-Victorin E.

Mol Cell Endocrinol. 2017 Jun 15;448:66-76. doi: 10.1016/j.mce.2017.03.025. Epub 2017 Mar 24.


Rosiglitazone drives cavin-2/SDPR expression in adipocytes in a CEBPα-dependent manner.

Hansson B, Rippe C, Kotowska D, Wasserstrom S, Säll J, Göransson O, Swärd K, Stenkula KG.

PLoS One. 2017 Mar 9;12(3):e0173412. doi: 10.1371/journal.pone.0173412. eCollection 2017.


Frequent low-level mutations of protein kinase D2 in angiolipoma.

Hofvander J, Arbajian E, Stenkula KG, Lindkvist-Petersson K, Larsson M, Nilsson J, Magnusson L, von Steyern FV, Rissler P, Hornick JL, Mertens F.

J Pathol. 2017 Apr;241(5):578-582. doi: 10.1002/path.4865. Epub 2017 Feb 27.


Thylakoids reduce body fat and fat cell size by binding to dietary fat making it less available for absorption in high-fat fed mice.

Stenkula KG, Stenblom EL, Montelius C, Egecioglu E, Erlanson-Albertsson C.

Nutr Metab (Lond). 2017 Jan 11;14:4. doi: 10.1186/s12986-016-0160-4. eCollection 2017.


Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation.

Hansen JS, Krintel C, Hernebring M, Haataja TJ, de Marè S, Wasserstrom S, Kosinska-Eriksson U, Palmgren M, Holm C, Stenkula KG, Jones HA, Lindkvist-Petersson K.

Metabolism. 2016 Dec;65(12):1731-1742. doi: 10.1016/j.metabol.2016.09.004. Epub 2016 Sep 22.


Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.

Säll J, Pettersson AM, Björk C, Henriksson E, Wasserstrom S, Linder W, Zhou Y, Hansson O, Andersson DP, Ekelund M, Degerman E, Stenkula KG, Laurencikiene J, Göransson O.

Diabetologia. 2017 Feb;60(2):314-323. doi: 10.1007/s00125-016-4141-y. Epub 2016 Nov 2.


Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion.

Salunkhe VA, Mollet IG, Ofori JK, Malm HA, Esguerra JL, Reinbothe TM, Stenkula KG, Wendt A, Eliasson L, Vikman J.

EBioMedicine. 2016 Aug;10:185-94. doi: 10.1016/j.ebiom.2016.07.007. Epub 2016 Jul 9.


Dual Actions of Apolipoprotein A-I on Glucose-Stimulated Insulin Secretion and Insulin-Independent Peripheral Tissue Glucose Uptake Lead to Increased Heart and Skeletal Muscle Glucose Disposal.

Domingo-Espín J, Lindahl M, Nilsson-Wolanin O, Cushman SW, Stenkula KG, Lagerstedt JO.

Diabetes. 2016 Jul;65(7):1838-48. doi: 10.2337/db15-1493. Epub 2016 Apr 19.


Adipose cell hypertrophy precedes the appearance of small adipocytes by 3 days in C57BL/6 mouse upon changing to a high fat diet.

Li Y, Periwal V, Cushman SW, Stenkula KG.

Adipocyte. 2015 Dec 8;5(1):81-7. doi: 10.1080/21623945.2015.1128588. eCollection 2016 Jan-Mar.


Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells.

Hansson B, Medina A, Fryklund C, Fex M, Stenkula KG.

Biochem Biophys Res Commun. 2016 May 27;474(2):357-363. doi: 10.1016/j.bbrc.2016.04.110. Epub 2016 Apr 22.


Emerging roles of the myocardin family of proteins in lipid and glucose metabolism.

Swärd K, Stenkula KG, Rippe C, Alajbegovic A, Gomez MF, Albinsson S.

J Physiol. 2016 Sep 1;594(17):4741-52. doi: 10.1113/JP271913. Epub 2016 May 10. Review.


ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation.

Lindahl M, Petrlova J, Dalla-Riva J, Wasserstrom S, Rippe C, Domingo-Espin J, Kotowska D, Krupinska E, Berggreen C, Jones HA, Swärd K, Lagerstedt JO, Göransson O, Stenkula KG.

J Lipid Res. 2015 Dec;56(12):2248-59. doi: 10.1194/jlr.M054767. Epub 2015 Oct 26.


Human adipose cells in vitro are either refractory or responsive to insulin, reflecting host metabolic state.

Lizunov VA, Stenkula KG, Blank PS, Troy A, Lee JP, Skarulis MC, Cushman SW, Zimmerberg J.

PLoS One. 2015 Mar 13;10(3):e0119291. doi: 10.1371/journal.pone.0119291. eCollection 2015.


SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.

Henriksson E, Säll J, Gormand A, Wasserstrom S, Morrice NA, Fritzen AM, Foretz M, Campbell DG, Sakamoto K, Ekelund M, Degerman E, Stenkula KG, Göransson O.

J Cell Sci. 2015 Feb 1;128(3):472-86.


Secondary structure changes in ApoA-I Milano (R173C) are not accompanied by a decrease in protein stability or solubility.

Petrlova J, Dalla-Riva J, Mörgelin M, Lindahl M, Krupinska E, Stenkula KG, Voss JC, Lagerstedt JO.

PLoS One. 2014 Apr 22;9(4):e96150. doi: 10.1371/journal.pone.0096150. eCollection 2014.


Adiponutrin: a multimeric plasma protein.

Winberg ME, Motlagh MK, Stenkula KG, Holm C, Jones HA.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):1114-9. doi: 10.1016/j.bbrc.2014.03.078. Epub 2014 Mar 26.


Single injections of apoA-I acutely improve in vivo glucose tolerance in insulin-resistant mice.

Stenkula KG, Lindahl M, Petrlova J, Dalla-Riva J, Göransson O, Cushman SW, Krupinska E, Jones HA, Lagerstedt JO.

Diabetologia. 2014 Apr;57(4):797-800. doi: 10.1007/s00125-014-3162-7. Epub 2014 Jan 18.


Insulin stimulates translocation of human GLUT4 to the membrane in fat bodies of transgenic Drosophila melanogaster.

Crivat G, Lizunov VA, Li CR, Stenkula KG, Zimmerberg J, Cushman SW, Pick L.

PLoS One. 2013 Nov 6;8(11):e77953. doi: 10.1371/journal.pone.0077953. eCollection 2013.


Impaired tethering and fusion of GLUT4 vesicles in insulin-resistant human adipose cells.

Lizunov VA, Lee JP, Skarulis MC, Zimmerberg J, Cushman SW, Stenkula KG.

Diabetes. 2013 Sep;62(9):3114-9. doi: 10.2337/db12-1741. Epub 2013 Jun 25.


Discoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle.

Dalla-Riva J, Stenkula KG, Petrlova J, Lagerstedt JO.

J Lipid Res. 2013 May;54(5):1275-82. doi: 10.1194/jlr.M032904. Epub 2013 Mar 7.


Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice.

Lizunov VA, Stenkula KG, Lisinski I, Gavrilova O, Yver DR, Chadt A, Al-Hasani H, Zimmerberg J, Cushman SW.

Am J Physiol Endocrinol Metab. 2012 Apr 15;302(8):E950-60. doi: 10.1152/ajpendo.00466.2011. Epub 2012 Jan 31.


Insulin controls the spatial distribution of GLUT4 on the cell surface through regulation of its postfusion dispersal.

Stenkula KG, Lizunov VA, Cushman SW, Zimmerberg J.

Cell Metab. 2010 Sep 8;12(3):250-9. doi: 10.1016/j.cmet.2010.08.005.


Guardian of corpulence: a hypothesis on p53 signaling in the fat cell.

Bazuine M, Stenkula KG, Cam M, Arroyo M, Cushman SW.

Clin Lipidol. 2009 Apr 1;4(2):231-243.


Human, but not rat, IRS1 targets to the plasma membrane in both human and rat adipocytes.

Stenkula KG, Thorn H, Franck N, Hallin E, Sauma L, Nystrom FH, Strålfors P.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):840-5. Epub 2007 Sep 24.


Insulin-induced GLUT4 translocation to the plasma membrane is blunted in large compared with small primary fat cells isolated from the same individual.

Franck N, Stenkula KG, Ost A, Lindström T, Strålfors P, Nystrom FH.

Diabetologia. 2007 Aug;50(8):1716-22. Epub 2007 Jun 16.


PPAR-gamma response element activity in intact primary human adipocytes: effects of fatty acids.

Sauma L, Stenkula KG, Kjølhede P, Strålfors P, Söderström M, Nystrom FH.

Nutrition. 2006 Jan;22(1):60-8. Epub 2005 Oct 12.


Expression of a mutant IRS inhibits metabolic and mitogenic signalling of insulin in human adipocytes.

Stenkula KG, Said L, Karlsson M, Thorn H, Kjølhede P, Gustavsson J, Söderström M, Strålfors P, Nystrom FH.

Mol Cell Endocrinol. 2004 Jun 30;221(1-2):1-8.


Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes. Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control.

Karlsson M, Thorn H, Danielsson A, Stenkula KG, Ost A, Gustavsson J, Nystrom FH, Strålfors P.

Eur J Biochem. 2004 Jun;271(12):2471-9.


Cell surface orifices of caveolae and localization of caveolin to the necks of caveolae in adipocytes.

Thorn H, Stenkula KG, Karlsson M, Ortegren U, Nystrom FH, Gustavsson J, Stralfors P.

Mol Biol Cell. 2003 Oct;14(10):3967-76. Epub 2003 Jul 11.

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