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Items: 1 to 50 of 91

1.

Correction to: Pesticide exposure among Bolivian farmers: associations between worker protection and exposure biomarkers.

Cuenca JB, Tirado N, Vikström M, Lindh CH, Stenius U, Leander K, Berglund M, Dreij K.

J Expo Sci Environ Epidemiol. 2019 Jun 14. doi: 10.1038/s41370-019-0149-y. [Epub ahead of print]

PMID:
31201360
2.

The Water Extract of Juniperus communis L. Induces Cell Death and Sensitizes Cancer Cells to Cytostatic Drugs through p53 and PI3K/Akt Pathways.

Raasmaja A, Stenius U, Ghalali A.

Int J Mol Sci. 2019 Apr 26;20(9). pii: E2054. doi: 10.3390/ijms20092054.

3.

Pesticide exposure among Bolivian farmers: associations between worker protection and exposure biomarkers.

Barrón Cuenca J, Tirado N, Vikström M, Lindh CH, Stenius U, Leander K, Berglund M, Dreij K.

J Expo Sci Environ Epidemiol. 2019 Feb 20. doi: 10.1038/s41370-019-0128-3. [Epub ahead of print] Erratum in: J Expo Sci Environ Epidemiol. 2019 Jun 14;:.

PMID:
30787424
4.

A neural classification method for supporting the creation of BioVerbNet.

Chiu B, Majewska O, Pyysalo S, Wey L, Stenius U, Korhonen A, Palmer M.

J Biomed Semantics. 2019 Jan 18;10(1):2. doi: 10.1186/s13326-018-0193-x.

5.

TGF beta promotes repair of bulky DNA damage through increased ERCC1/XPF and ERCC1/XPA interaction.

Zheng H, Jarvis IWH, Bottai M, Dreij K, Stenius U.

Carcinogenesis. 2019 Jun 10;40(4):580-591. doi: 10.1093/carcin/bgy156.

PMID:
30418489
6.

CXADR-Mediated Formation of an AKT Inhibitory Signalosome at Tight Junctions Controls Epithelial-Mesenchymal Plasticity in Breast Cancer.

Nilchian A, Johansson J, Ghalali A, Asanin ST, Santiago A, Rosencrantz O, Sollerbrant K, Vincent CT, Sund M, Stenius U, Fuxe J.

Cancer Res. 2019 Jan 1;79(1):47-60. doi: 10.1158/0008-5472.CAN-18-1742. Epub 2018 Nov 1.

PMID:
30385615
7.

LION LBD: a literature-based discovery system for cancer biology.

Pyysalo S, Baker S, Ali I, Haselwimmer S, Shah T, Young A, Guo Y, Högberg J, Stenius U, Narita M, Korhonen A.

Bioinformatics. 2019 May 1;35(9):1553-1561. doi: 10.1093/bioinformatics/bty845.

8.

Toluene diisocyanate exposure and autotaxin-lysophosphatidic acid signalling.

Broström JM, Ghalali A, Zheng H, Högberg J, Stenius U, Littorin M, Tinnerberg H, Broberg K.

Toxicol Appl Pharmacol. 2018 Sep 15;355:43-51. doi: 10.1016/j.taap.2018.06.019. Epub 2018 Jun 22.

PMID:
29940203
9.

Cancer Hallmarks Analytics Tool (CHAT): a text mining approach to organize and evaluate scientific literature on cancer.

Baker S, Ali I, Silins I, Pyysalo S, Guo Y, Högberg J, Stenius U, Korhonen A.

Bioinformatics. 2017 Dec 15;33(24):3973-3981. doi: 10.1093/bioinformatics/btx454.

10.

ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?

Zheng H, Högberg J, Stenius U.

Carcinogenesis. 2017 Dec 7;38(12):1196-1206. doi: 10.1093/carcin/bgx100.

PMID:
28968864
11.

Cancer Risk Assessment of Airborne PAHs Based on in Vitro Mixture Potency Factors.

Dreij K, Mattsson Å, Jarvis IWH, Lim H, Hurkmans J, Gustafsson J, Bergvall C, Westerholm R, Johansson C, Stenius U.

Environ Sci Technol. 2017 Aug 1;51(15):8805-8814. doi: 10.1021/acs.est.7b02963. Epub 2017 Jul 11.

PMID:
28650627
12.

Text mining for improved exposure assessment.

Larsson K, Baker S, Silins I, Guo Y, Stenius U, Korhonen A, Berglund M.

PLoS One. 2017 Mar 3;12(3):e0173132. doi: 10.1371/journal.pone.0173132. eCollection 2017.

13.

Atorvastatin Decreases HBx-Induced Phospho-Akt in Hepatocytes via P2X Receptors.

Ghalali A, Martin-Renedo J, Högberg J, Stenius U.

Mol Cancer Res. 2017 Jun;15(6):714-722. doi: 10.1158/1541-7786.MCR-16-0373. Epub 2017 Feb 16.

14.

Corrigendum to "PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a" [Chem. Biol. Interact. 219 (2014)].

Al-Anati L, Kadekar S, Högberg J, Stenius U.

Chem Biol Interact. 2017 Apr 25;268:148. doi: 10.1016/j.cbi.2017.01.024. Epub 2017 Feb 7. No abstract available.

PMID:
28187856
15.
16.

MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 IS ACTIVATED IN RESPONSE TO INHIBITED Akt SIGNALING.

Malmlöf M, Roudier E, Högberg J, Stenius U.

J Biol Chem. 2016 Dec 16;291(51):26588. No abstract available.

17.

Exposure to polychlorinated biphenyls and prostate cancer: population-based prospective cohort and experimental studies.

Ali I, Julin B, Glynn A, Högberg J, Berglund M, Johansson JE, Andersson SO, Andrén O, Giovannucci E, Wolk A, Stenius U, Åkesson A.

Carcinogenesis. 2016 Dec;37(12):1144-1151. Epub 2016 Oct 7.

PMID:
27742691
18.

Gender differences in cancer susceptibility: role of oxidative stress.

Ali I, Högberg J, Hsieh JH, Auerbach S, Korhonen A, Stenius U, Silins I.

Carcinogenesis. 2016 Oct;37(10):985-992. doi: 10.1093/carcin/bgw076. Epub 2016 Jul 31.

19.

Grouping chemicals for health risk assessment: A text mining-based case study of polychlorinated biphenyls (PCBs).

Ali I, Guo Y, Silins I, Högberg J, Stenius U, Korhonen A.

Toxicol Lett. 2016 Jan 22;241:32-7. doi: 10.1016/j.toxlet.2015.11.003. Epub 2015 Nov 10.

PMID:
26562772
20.

Automatic semantic classification of scientific literature according to the hallmarks of cancer.

Baker S, Silins I, Guo Y, Ali I, Högberg J, Stenius U, Korhonen A.

Bioinformatics. 2016 Feb 1;32(3):432-40. doi: 10.1093/bioinformatics/btv585. Epub 2015 Oct 9.

PMID:
26454282
21.

Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene.

Al-Anati L, Viluksela M, Strid A, Bergman Å, Andersson PL, Stenius U, Högberg J.

Chem Biol Interact. 2015 Sep 5;239:164-73. doi: 10.1016/j.cbi.2015.07.002. Epub 2015 Jul 4.

PMID:
26148434
22.

Toluene diisocyanate: Induction of the autotaxin-lysophosphatidic acid axis and its association with airways symptoms.

Broström JM, Ye ZW, Axmon A, Littorin M, Tinnerberg H, Lindh CH, Zheng H, Ghalali A, Stenius U, Jönsson BA, Högberg J.

Toxicol Appl Pharmacol. 2015 Sep 15;287(3):222-31. doi: 10.1016/j.taap.2015.06.006. Epub 2015 Jun 11.

PMID:
26072274
23.

Cadmium at nanomolar concentrations activates Raf-MEK-ERK1/2 MAPKs signaling via EGFR in human cancer cell lines.

Ali I, Damdimopoulou P, Stenius U, Halldin K.

Chem Biol Interact. 2015 Apr 25;231:44-52. doi: 10.1016/j.cbi.2015.02.014. Epub 2015 Mar 2.

PMID:
25744307
24.

Detection of benz[j]aceanthrylene in urban air and evaluation of its genotoxic potential.

Lim H, Mattsson Å, Jarvis IW, Bergvall C, Bottai M, Morales DA, Kummrow F, Umbuzeiro GA, Stenius U, Westerholm R, Dreij K.

Environ Sci Technol. 2015 Mar 3;49(5):3101-9. doi: 10.1021/es505458g. Epub 2015 Feb 9.

PMID:
25625372
25.

Unsupervised discovery of information structure in biomedical documents.

Kiela D, Guo Y, Stenius U, Korhonen A.

Bioinformatics. 2015 Apr 1;31(7):1084-92. doi: 10.1093/bioinformatics/btu758. Epub 2014 Nov 18.

PMID:
25411329
26.

Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats.

Viluksela M, Heikkinen P, van der Ven LT, Rendel F, Roos R, Esteban J, Korkalainen M, Lensu S, Miettinen HM, Savolainen K, Sankari S, Lilienthal H, Adamsson A, Toppari J, Herlin M, Finnilä M, Tuukkanen J, Leslie HA, Hamers T, Hamscher G, Al-Anati L, Stenius U, Dervola KS, Bogen IL, Fonnum F, Andersson PL, Schrenk D, Halldin K, Håkansson H.

PLoS One. 2014 Aug 19;9(8):e104639. doi: 10.1371/journal.pone.0104639. eCollection 2014.

27.

Evaluation of carcinogenic modes of action for pesticides in fruit on the Swedish market using a text-mining tool.

Silins I, Korhonen A, Stenius U.

Front Pharmacol. 2014 Jun 23;5:145. doi: 10.3389/fphar.2014.00145. eCollection 2014.

28.

PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a.

Al-Anati L, Kadekar S, Högberg J, Stenius U.

Chem Biol Interact. 2014 Aug 5;219:159-67. doi: 10.1016/j.cbi.2014.06.007. Epub 2014 Jun 19. Erratum in: Chem Biol Interact. 2017 Apr 25;268:148.

PMID:
24954032
29.

Benzo[a]pyrene-specific online high-performance liquid chromatography fractionation of air particulate extracts - a tool for evaluating biological interactions.

Lim H, Bergvall C, Jarvis I, Mattsson Å, Dreij K, Stenius U, Westerholm R.

J Chromatogr A. 2014 Aug 15;1355:100-6. doi: 10.1016/j.chroma.2014.05.082. Epub 2014 Jun 8.

PMID:
24947883
30.

Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells.

Jarvis IW, Bergvall C, Morales DA, Kummrow F, Umbuzeiro GA, Westerholm R, Stenius U, Dreij K.

Toxicol Lett. 2014 Aug 17;229(1):25-32. doi: 10.1016/j.toxlet.2014.06.013. Epub 2014 Jun 6.

PMID:
24910982
31.

Interactions between polycyclic aromatic hydrocarbons in complex mixtures and implications for cancer risk assessment.

Jarvis IW, Dreij K, Mattsson Å, Jernström B, Stenius U.

Toxicology. 2014 Jul 3;321:27-39. doi: 10.1016/j.tox.2014.03.012. Epub 2014 Apr 5. Review.

PMID:
24713297
32.
33.

Sensitivity of Salmonella YG5161 for detecting PAH-associated mutagenicity in air particulate matter.

Umbuzeiro GA, Kummrow F, Morales DA, Alves DK, Lim H, Jarvis IW, Bergvall C, Westerholm R, Stenius U, Dreij K.

Environ Mol Mutagen. 2014 Jul;55(6):510-7. doi: 10.1002/em.21861. Epub 2014 Feb 28.

PMID:
24578285
34.

Atorvastatin prevents ATP-driven invasiveness via P2X7 and EHBP1 signaling in PTEN-expressing prostate cancer cells.

Ghalali A, Wiklund F, Zheng H, Stenius U, Högberg J.

Carcinogenesis. 2014 Jul;35(7):1547-55. doi: 10.1093/carcin/bgu019. Epub 2014 Jan 22.

PMID:
24451147
35.

Active learning-based information structure analysis of full scientific articles and two applications for biomedical literature review.

Guo Y, Silins I, Stenius U, Korhonen A.

Bioinformatics. 2013 Jun 1;29(11):1440-7. doi: 10.1093/bioinformatics/btt163. Epub 2013 Apr 5.

PMID:
23564844
36.

Persistent activation of DNA damage signaling in response to complex mixtures of PAHs in air particulate matter.

Jarvis IW, Bergvall C, Bottai M, Westerholm R, Stenius U, Dreij K.

Toxicol Appl Pharmacol. 2013 Feb 1;266(3):408-18. doi: 10.1016/j.taap.2012.11.026. Epub 2012 Dec 5.

PMID:
23220466
37.

Exocrine pancreatic carcinogenesis and autotaxin expression.

Kadekar S, Silins I, Korhonen A, Dreij K, Al-Anati L, Högberg J, Stenius U.

PLoS One. 2012;7(8):e43209. doi: 10.1371/journal.pone.0043209. Epub 2012 Aug 29.

38.

Gender differences in chemical carcinogenesis in National Toxicology Program 2-year bioassays.

Kadekar S, Peddada S, Silins I, French JE, Högberg J, Stenius U.

Toxicol Pathol. 2012 Dec;40(8):1160-8. doi: 10.1177/0192623312446527. Epub 2012 May 14.

39.

Text mining for literature review and knowledge discovery in cancer risk assessment and research.

Korhonen A, Séaghdha DO, Silins I, Sun L, Högberg J, Stenius U.

PLoS One. 2012;7(4):e33427. doi: 10.1371/journal.pone.0033427. Epub 2012 Apr 12.

40.

γH2AX, pChk1, and Wip1 as potential markers of persistent DNA damage derived from dibenzo[a,l]pyrene and PAH-containing extracts from contaminated soils.

Niziolek-Kierecka M, Dreij K, Lundstedt S, Stenius U.

Chem Res Toxicol. 2012 Apr 16;25(4):862-72. doi: 10.1021/tx200436n. Epub 2012 Mar 22.

PMID:
22409540
41.

Cadmium-induced effects on cellular signaling pathways in the liver of transgenic estrogen reporter mice.

Ali I, Damdimopoulou P, Stenius U, Adamsson A, Mäkelä SI, Åkesson A, Berglund M, Håkansson H, Halldin K.

Toxicol Sci. 2012 May;127(1):66-75. doi: 10.1093/toxsci/kfs077. Epub 2012 Feb 7.

PMID:
22314386
42.

Data and literature gathering in chemical cancer risk assessment.

Silins I, Korhonen A, Högberg J, Stenius U.

Integr Environ Assess Manag. 2012 Jul;8(3):412-7. doi: 10.1002/ieam.1278. Epub 2012 Mar 13.

PMID:
22275076
43.

Silencing p110β prevents rapid depletion of nuclear pAkt.

Ye ZW, Ghalali A, Högberg J, Stenius U.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):613-8. doi: 10.1016/j.bbrc.2011.10.120. Epub 2011 Nov 3.

PMID:
22074824
44.

Statins exhibit anticancer effects through modifications of the pAkt signaling pathway.

Miraglia E, Högberg J, Stenius U.

Int J Oncol. 2012 Mar;40(3):867-75. doi: 10.3892/ijo.2011.1223. Epub 2011 Oct 6.

PMID:
21994073
45.

Weakly supervised learning of information structure of scientific abstracts--is it accurate enough to benefit real-world tasks in biomedicine?

Guo Y, Korhonen A, Silins I, Stenius U.

Bioinformatics. 2011 Nov 15;27(22):3179-85. doi: 10.1093/bioinformatics/btr536. Epub 2011 Sep 22.

PMID:
21949269
46.

Multivariate toxicity profiles and QSAR modeling of non-dioxin-like PCBs--an investigation of in vitro screening data from ultra-pure congeners.

Stenberg M, Hamers T, Machala M, Fonnum F, Stenius U, Lauy AA, van Duursen MB, Westerink RH, Fernandes EC, Andersson PL.

Chemosphere. 2011 Nov;85(9):1423-9. doi: 10.1016/j.chemosphere.2011.08.019. Epub 2011 Sep 3.

PMID:
21890175
47.

A comparison and user-based evaluation of models of textual information structure in the context of cancer risk assessment.

Guo Y, Korhonen A, Liakata M, Silins I, Hogberg J, Stenius U.

BMC Bioinformatics. 2011 Mar 8;12:69. doi: 10.1186/1471-2105-12-69.

48.

Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis.

Al-Anati L, Högberg J, Stenius U.

Toxicol Appl Pharmacol. 2010 Dec 1;249(2):166-77. doi: 10.1016/j.taap.2010.09.004. Epub 2010 Sep 16.

PMID:
20840854
49.

Purinergic receptor-mediated rapid depletion of nuclear phosphorylated Akt depends on pleckstrin homology domain leucine-rich repeat phosphatase, calcineurin, protein phosphatase 2A, and PTEN phosphatases.

Mistafa O, Ghalali A, Kadekar S, Högberg J, Stenius U.

J Biol Chem. 2010 Sep 3;285(36):27900-10. doi: 10.1074/jbc.M110.117093. Epub 2010 Jul 6.

50.

Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway.

Ali I, Penttinen-Damdimopoulou PE, Mäkelä SI, Berglund M, Stenius U, Akesson A, Håkansson H, Halldin K.

Environ Health Perspect. 2010 Oct;118(10):1389-94. doi: 10.1289/ehp.1001967. Epub 2010 Jun 4.

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