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Items: 1 to 50 of 81

1.

Hybrid vesicles as intracellular reactive oxygen species and nitric oxide generators.

Zhang Y, Gal N, Itel F, Westensee IN, Brodszkij E, Mayer D, Stenger S, Castellote-Borrell M, Boesen T, Tabaei SR, Höök F, Städler B.

Nanoscale. 2019 Jun 20;11(24):11530-11541. doi: 10.1039/c9nr02584g.

PMID:
31150038
2.

The tyrosine kinase inhibitor dasatinib reduces the growth of intracellular Mycobacterium tuberculosis despite impairing T-cell function.

Wehrstedt S, Kubis J, Zimmermann A, Bruns H, Mayer D, Grieshober M, Stenger S.

Eur J Immunol. 2018 Nov;48(11):1892-1903. doi: 10.1002/eji.201847656. Epub 2018 Oct 9.

PMID:
30242834
3.

The Opioid Crisis in Missouri: A Call to Action for Physicians, Legislators, and Society.

Lewis L, Carpenter CR, Schwarz ES, Jotte RS, Waller C, Winograd R, Williams R, Stenger S, Rehder H, Governick S, Giuffra L.

Mo Med. 2017 Nov-Dec;114(6):440-446.

4.

Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria.

Balin SJ, Pellegrini M, Klechevsky E, Won ST, Weiss DI, Choi AW, Hakimian J, Lu J, Ochoa MT, Bloom BR, Lanier LL, Stenger S, Modlin RL.

Sci Immunol. 2018 Aug 31;3(26). pii: eaat7668. doi: 10.1126/sciimmunol.aat7668.

5.

Phospholipid-Block Copolymer Hybrid Vesicles with Lysosomal Escape Ability.

Zong W, Thingholm B, Itel F, Schattling PS, Brodszkij E, Mayer D, Stenger S, Goldie KN, Han X, Städler B.

Langmuir. 2018 Jun 12;34(23):6874-6886. doi: 10.1021/acs.langmuir.8b01073. Epub 2018 Jun 1.

PMID:
29776311
6.

Lectin-Functionalized Composite Hydrogels for "Capture-and-Killing" of Carbapenem-Resistant Pseudomonas aeruginosa.

Bodenberger N, Kubiczek D, Halbgebauer D, Rimola V, Wiese S, Mayer D, Rodriguez Alfonso AA, Ständker L, Stenger S, Rosenau F.

Biomacromolecules. 2018 Jul 9;19(7):2472-2482. doi: 10.1021/acs.biomac.8b00089. Epub 2018 Apr 25.

PMID:
29665678
7.

Pulmonary immune responses to Mycobacterium tuberculosis in exposed individuals.

Herzmann C, Ernst M, Lange C, Stenger S, Kaufmann SHE, Reiling N, Schaberg T, van der Merwe L, Maertzdorf J; Tb or not Tb consortium.

PLoS One. 2017 Nov 10;12(11):e0187882. doi: 10.1371/journal.pone.0187882. eCollection 2017.

8.

TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.

Kaufmann SHE, Dockrell HM, Drager N, Ho MM, McShane H, Neyrolles O, Ottenhoff THM, Patel B, Roordink D, Spertini F, Stenger S, Thole J, Verreck FAW, Williams A; TBVAC2020 Consortium.

Front Immunol. 2017 Oct 4;8:1203. doi: 10.3389/fimmu.2017.01203. eCollection 2017. Review.

9.

Inhibitors of the Diadenosine Tetraphosphate Phosphorylase Rv2613c of Mycobacterium tuberculosis.

Götz KH, Hacker SM, Mayer D, Dürig JN, Stenger S, Marx A.

ACS Chem Biol. 2017 Oct 20;12(10):2682-2689. doi: 10.1021/acschembio.7b00653. Epub 2017 Sep 26.

PMID:
28892605
10.

Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages.

Steiger J, Stephan A, Inkeles MS, Realegeno S, Bruns H, Kröll P, de Castro Kroner J, Sommer A, Batinica M, Pitzler L, Kalscheuer R, Hartmann P, Plum G, Stenger S, Pellegrini M, Brachvogel B, Modlin RL, Fabri M.

J Immunol. 2016 Jul 1;197(1):222-32. doi: 10.4049/jimmunol.1502407. Epub 2016 May 27.

11.

[CAPNETZ. The competence network for community-acquired pneumonia (CAP)].

Suttorp N, Welte T, Marre R, Stenger S, Pletz M, Rupp J, Schütte H, Rohde G; CAPNETZ-Studiengruppe.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2016 Apr;59(4):475-81. doi: 10.1007/s00103-016-2318-7. German.

PMID:
26984399
12.

Lipoarabinomannan-Responsive Polycytotoxic T Cells Are Associated with Protection in Human Tuberculosis.

Busch M, Herzmann C, Kallert S, Zimmermann A, Höfer C, Mayer D, Zenk SF, Muche R, Lange C, Bloom BR, Modlin RL, Stenger S; TBornotTB Network.

Am J Respir Crit Care Med. 2016 Aug 1;194(3):345-55. doi: 10.1164/rccm.201509-1746OC.

13.

Hypoxia promotes Mycobacterium tuberculosis-specific up-regulation of granulysin in human T cells.

Zenk SF, Vollmer M, Schercher E, Kallert S, Kubis J, Stenger S.

Med Microbiol Immunol. 2016 Jun;205(3):219-29. doi: 10.1007/s00430-015-0442-x. Epub 2015 Nov 27.

PMID:
26613797
14.

Liposomal delivery of lipoarabinomannan triggers Mycobacterium tuberculosis specific T-cells.

Kallert S, Zenk SF, Walther P, Grieshober M, Weil T, Stenger S.

Tuberculosis (Edinb). 2015 Jul;95(4):452-62. doi: 10.1016/j.tube.2015.04.001. Epub 2015 May 19.

PMID:
26043674
15.

Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells.

Herzmann C, Sotgiu G, Schaberg T, Ernst M, Stenger S, Lange C; TB or not TB Consortium.

Tuberculosis (Edinb). 2015 May;95(3):321-7. doi: 10.1016/j.tube.2015.02.044. Epub 2015 Feb 28.

PMID:
25794470
16.

Early BCG vaccination is unrelated to pulmonary immunity against Mycobacterium tuberculosis in adults.

Herzmann C, Sotgiu G, Schaberg T, Ernst M, Stenger S, Lange C; German TB or Not TB Consortium.

Eur Respir J. 2014 Oct;44(4):1087-90. doi: 10.1183/09031936.00086514. Epub 2014 Jun 25. No abstract available.

17.

New insights into the interaction of Mycobacterium tuberculosis and human macrophages.

Bruns H, Stenger S.

Future Microbiol. 2014;9(3):327-41. doi: 10.2217/fmb.13.164. Review.

PMID:
24762307
18.

Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses.

Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL.

Science. 2013 Mar 22;339(6126):1448-53. doi: 10.1126/science.1233665. Epub 2013 Feb 28.

19.

CD40 ligand and interferon-γ induce an antimicrobial response against Mycobacterium tuberculosis in human monocytes.

Klug-Micu GM, Stenger S, Sommer A, Liu PT, Krutzik SR, Modlin RL, Fabri M.

Immunology. 2013 May;139(1):121-8. doi: 10.1111/imm.12062.

20.

Galectin-3 regulates the innate immune response of human monocytes.

Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ.

J Infect Dis. 2013 Mar 15;207(6):947-56. doi: 10.1093/infdis/jis920. Epub 2012 Dec 18.

21.

Azurophil granule proteins constitute the major mycobactericidal proteins in human neutrophils and enhance the killing of mycobacteria in macrophages.

Jena P, Mohanty S, Mohanty T, Kallert S, Morgelin M, Lindstrøm T, Borregaard N, Stenger S, Sonawane A, Sørensen OE.

PLoS One. 2012;7(12):e50345. doi: 10.1371/journal.pone.0050345. Epub 2012 Dec 14.

22.

Abelson tyrosine kinase controls phagosomal acidification required for killing of Mycobacterium tuberculosis in human macrophages.

Bruns H, Stegelmann F, Fabri M, Döhner K, van Zandbergen G, Wagner M, Skinner M, Modlin RL, Stenger S.

J Immunol. 2012 Oct 15;189(8):4069-78. doi: 10.4049/jimmunol.1201538. Epub 2012 Sep 17.

23.

Increased frequencies of pulmonary regulatory T-cells in latent Mycobacterium tuberculosis infection.

Herzmann C, Ernst M, Ehlers S, Stenger S, Maertzdorf J, Sotgiu G, Lange C.

Eur Respir J. 2012 Dec;40(6):1450-7. doi: 10.1183/09031936.00214611. Epub 2012 Mar 22.

24.

Hypoxia triggers the expression of human β defensin 2 and antimicrobial activity against Mycobacterium tuberculosis in human macrophages.

Nickel D, Busch M, Mayer D, Hagemann B, Knoll V, Stenger S.

J Immunol. 2012 Apr 15;188(8):4001-7. doi: 10.4049/jimmunol.1100976. Epub 2012 Mar 16.

25.

Copper and silver ion implantation of aluminium oxide-blasted titanium surfaces: proliferative response of osteoblasts and antibacterial effects.

Fiedler J, Kolitsch A, Kleffner B, Henke D, Stenger S, Brenner RE.

Int J Artif Organs. 2011 Sep;34(9):882-8. doi: 10.5301/ijao.5000022.

PMID:
22094570
26.

Vitamin D is required for IFN-gamma-mediated antimicrobial activity of human macrophages.

Fabri M, Stenger S, Shin DM, Yuk JM, Liu PT, Realegeno S, Lee HM, Krutzik SR, Schenk M, Sieling PA, Teles R, Montoya D, Iyer SS, Bruns H, Lewinsohn DM, Hollis BW, Hewison M, Adams JS, Steinmeyer A, Zügel U, Cheng G, Jo EK, Bloom BR, Modlin RL.

Sci Transl Med. 2011 Oct 12;3(104):104ra102. doi: 10.1126/scitranslmed.3003045.

27.

Structural differences in lipomannans from pathogenic and nonpathogenic mycobacteria that impact CD1b-restricted T cell responses.

Torrelles JB, Sieling PA, Arcos J, Knaup R, Bartling C, Rajaram MV, Stenger S, Modlin RL, Schlesinger LS.

J Biol Chem. 2011 Oct 14;286(41):35438-46. doi: 10.1074/jbc.M111.232587. Epub 2011 Aug 22.

28.

Measuring the killing of intracellular pathogens: Leishmania.

Stenger S, van Zandbergen G.

Curr Protoc Immunol. 2011 Apr;Chapter 14:Unit14.23. doi: 10.1002/0471142735.im1423s93.

PMID:
21462165
29.

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.

Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R.

J Immunol. 2010 Mar 15;184(6):2756-60. doi: 10.4049/jimmunol.0904013. Epub 2010 Feb 17.

30.

Corynebacterium canis sp. nov., isolated from a wound infection caused by a dog bite.

Funke G, Englert R, Frodl R, Bernard KA, Stenger S.

Int J Syst Evol Microbiol. 2010 Nov;60(Pt 11):2544-7. doi: 10.1099/ijs.0.019927-0. Epub 2009 Dec 11.

PMID:
20008112
31.

Interferon-gamma release assay in the ascites: Early hint for diagnosis of abdominal tuberculosis.

Lorenz R, Würl P, Haerter G, Cammerer G, Barth T, Hausladen S, Stenger S, Kern P.

Infection. 2010 Feb;38(1):69-72. doi: 10.1007/s15010-009-9469-5. Epub 2009 Nov 10.

PMID:
19904487
32.

Actinomyces hominis sp. nov., isolated from a wound swab.

Funke G, Englert R, Frodl R, Bernard KA, Stenger S.

Int J Syst Evol Microbiol. 2010 Jul;60(Pt 7):1678-81. doi: 10.1099/ijs.0.015818-0. Epub 2009 Sep 4.

PMID:
19734287
33.

Chlamydia pneumoniae hides inside apoptotic neutrophils to silently infect and propagate in macrophages.

Rupp J, Pfleiderer L, Jugert C, Moeller S, Klinger M, Dalhoff K, Solbach W, Stenger S, Laskay T, van Zandbergen G.

PLoS One. 2009 Jun 23;4(6):e6020. doi: 10.1371/journal.pone.0006020.

34.

Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans.

Bruns H, Meinken C, Schauenberg P, Härter G, Kern P, Modlin RL, Antoni C, Stenger S.

J Clin Invest. 2009 May;119(5):1167-77. doi: 10.1172/JCI38482. Epub 2009 Apr 20.

35.

Mycolic acids constitute a scaffold for mycobacterial lipid antigens stimulating CD1-restricted T cells.

Layre E, Collmann A, Bastian M, Mariotti S, Czaplicki J, Prandi J, Mori L, Stenger S, De Libero G, Puzo G, Gilleron M.

Chem Biol. 2009 Jan 30;16(1):82-92. doi: 10.1016/j.chembiol.2008.11.008.

36.

IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway.

Krutzik SR, Hewison M, Liu PT, Robles JA, Stenger S, Adams JS, Modlin RL.

J Immunol. 2008 Nov 15;181(10):7115-20.

37.

Mycobacterial lipopeptides elicit CD4+ CTLs in Mycobacterium tuberculosis-infected humans.

Bastian M, Braun T, Bruns H, Röllinghoff M, Stenger S.

J Immunol. 2008 Mar 1;180(5):3436-46.

38.
39.

Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens.

Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S.

J Immunol. 2006 Aug 1;177(3):1864-71. Erratum in: J Immunol. 2008 Jan 1;180(1):664.

40.

LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells.

Haraguchi S, Day NK, Kamchaisatian W, Beigier-Pompadre M, Stenger S, Tangsinmankong N, Sleasman JW, Pizzo SV, Cianciolo GJ.

AIDS Res Ther. 2006 Mar 31;3:8.

41.

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.

Liu PT, Stenger S, Li H, Wenzel L, Tan BH, Krutzik SR, Ochoa MT, Schauber J, Wu K, Meinken C, Kamen DL, Wagner M, Bals R, Steinmeyer A, Zügel U, Gallo RL, Eisenberg D, Hewison M, Hollis BW, Adams JS, Bloom BR, Modlin RL.

Science. 2006 Mar 24;311(5768):1770-3. Epub 2006 Feb 23.

42.

Coordinate expression of CC chemokine ligand 5, granulysin, and perforin in CD8+ T cells provides a host defense mechanism against Mycobacterium tuberculosis.

Stegelmann F, Bastian M, Swoboda K, Bhat R, Kiessler V, Krensky AM, Roellinghoff M, Modlin RL, Stenger S.

J Immunol. 2005 Dec 1;175(11):7474-83.

43.

Immunological control of tuberculosis: role of tumour necrosis factor and more.

Stenger S.

Ann Rheum Dis. 2005 Nov;64 Suppl 4:iv24-8. Review.

44.

Inverse correlation of maturity and antibacterial activity in human dendritic cells.

Buettner M, Meinken C, Bastian M, Bhat R, Stössel E, Faller G, Cianciolo G, Ficker J, Wagner M, Röllinghoff M, Stenger S.

J Immunol. 2005 Apr 1;174(7):4203-9.

45.

The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens.

Sieling PA, Torrelles JB, Stenger S, Chung W, Burdick AE, Rea TH, Brennan PJ, Belisle JT, Porcelli SA, Modlin RL.

J Immunol. 2005 Mar 1;174(5):2637-44.

46.

Diacylated sulfoglycolipids are novel mycobacterial antigens stimulating CD1-restricted T cells during infection with Mycobacterium tuberculosis.

Gilleron M, Stenger S, Mazorra Z, Wittke F, Mariotti S, Böhmer G, Prandi J, Mori L, Puzo G, De Libero G.

J Exp Med. 2004 Mar 1;199(5):649-59. Epub 2004 Feb 23.

47.

NK cells, but not NKT cells, are involved in Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in mice.

Mühlen KA, Schümann J, Wittke F, Stenger S, Van Rooijen N, Van Kaer L, Tiegs G.

J Immunol. 2004 Mar 1;172(5):3034-41.

48.

Use of genetic profiling in leprosy to discriminate clinical forms of the disease.

Bleharski JR, Li H, Meinken C, Graeber TG, Ochoa MT, Yamamura M, Burdick A, Sarno EN, Wagner M, Röllinghoff M, Rea TH, Colonna M, Stenger S, Bloom BR, Eisenberg D, Modlin RL.

Science. 2003 Sep 12;301(5639):1527-30.

49.

A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response.

Bleharski JR, Kiessler V, Buonsanti C, Sieling PA, Stenger S, Colonna M, Modlin RL.

J Immunol. 2003 Apr 1;170(7):3812-8.

50.

Human NKT cells express granulysin and exhibit antimycobacterial activity.

Gansert JL, Kiessler V, Engele M, Wittke F, Röllinghoff M, Krensky AM, Porcelli SA, Modlin RL, Stenger S.

J Immunol. 2003 Mar 15;170(6):3154-61.

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