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Items: 1 to 50 of 55

1.

The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach.

Chou HT, Apelt L, Farrell DP, White SR, Woodsmith J, Svetlov V, Goldstein JS, Nager AR, Li Z, Muller J, Dollfus H, Nudler E, Stelzl U, DiMaio F, Nachury MV, Walz T.

Structure. 2019 Sep 3;27(9):1384-1394.e4. doi: 10.1016/j.str.2019.06.006. Epub 2019 Jul 11.

PMID:
31303482
2.

Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system.

Rinaldi L, Delle Donne R, Catalanotti B, Torres-Quesada O, Enzler F, Moraca F, Nisticò R, Chiuso F, Piccinin S, Bachmann V, Lindner HH, Garbi C, Scorziello A, Russo NA, Synofzik M, Stelzl U, Annunziato L, Stefan E, Feliciello A.

Nat Commun. 2019 Jun 12;10(1):2572. doi: 10.1038/s41467-019-10037-y.

3.

Advancing Biomarker Development Through Convergent Engagement: Summary Report of the 2nd International Danube Symposium on Biomarker Development, Molecular Imaging and Applied Diagnostics; March 14-16, 2018; Vienna, Austria.

Lim MS, Beyer T, Babayan A, Bergmann M, Brehme M, Buyx A, Czernin J, Egger G, Elenitoba-Johnson KSJ, Gückel B, Jačan A, Haslacher H, Hicks RJ, Kenner L, Langanke M, Mitterhauser M, Pichler BJ, Salih HR, Schibli R, Schulz S, Simecek J, Simon J, Soares MO, Stelzl U, Wadsak W, Zatloukal K, Zeitlinger M, Hacker M.

Mol Imaging Biol. 2019 May 2. doi: 10.1007/s11307-019-01361-2. [Epub ahead of print]

PMID:
31049831
4.

Phosphorylation of the Bruchpilot N-terminus in Drosophila unlocks axonal transport of active zone building blocks.

Driller JH, Lützkendorf J, Depner H, Siebert M, Kuropka B, Weise C, Piao C, Petzoldt AG, Lehmann M, Stelzl U, Zahedi R, Sickmann A, Freund C, Sigrist SJ, Wahl MC.

J Cell Sci. 2019 Mar 18;132(6). pii: jcs225151. doi: 10.1242/jcs.225151.

5.

Interaction modulation through arrays of clustered methyl-arginine protein modifications.

Woodsmith J, Casado-Medrano V, Benlasfer N, Eccles RL, Hutten S, Heine CL, Thormann V, Abou-Ajram C, Rocks O, Dormann D, Stelzl U.

Life Sci Alliance. 2018 Sep 21;1(5):e201800178. doi: 10.26508/lsa.201800178. eCollection 2018 Oct.

6.

Understanding Disease Variants through the Lens of Protein Interactions.

Woodsmith J, Stelzl U.

Cell Syst. 2017 Dec 27;5(6):544-546. doi: 10.1016/j.cels.2017.12.009.

7.

Protein interaction perturbation profiling at amino-acid resolution.

Woodsmith J, Apelt L, Casado-Medrano V, Özkan Z, Timmermann B, Stelzl U.

Nat Methods. 2017 Dec;14(12):1213-1221. doi: 10.1038/nmeth.4464. Epub 2017 Oct 16.

PMID:
29039417
8.

A new role for FBP21 as regulator of Brr2 helicase activity.

Henning LM, Santos KF, Sticht J, Jehle S, Lee CT, Wittwer M, Urlaub H, Stelzl U, Wahl MC, Freund C.

Nucleic Acids Res. 2017 Jul 27;45(13):7922-7937. doi: 10.1093/nar/gkx535.

9.

Defining Human Tyrosine Kinase Phosphorylation Networks Using Yeast as an In Vivo Model Substrate.

Corwin T, Woodsmith J, Apelt F, Fontaine JF, Meierhofer D, Helmuth J, Grossmann A, Andrade-Navarro MA, Ballif BA, Stelzl U.

Cell Syst. 2017 Aug 23;5(2):128-139.e4. doi: 10.1016/j.cels.2017.08.001.

10.

Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor.

Birth P, Schöne S, Stelzl U, Meijsing SH.

PLoS One. 2017 Jul 14;12(7):e0181219. doi: 10.1371/journal.pone.0181219. eCollection 2017.

11.

Bioinformatics Analysis of PTM-Modified Protein Interaction Networks and Complexes.

Woodsmith J, Stelzl U, Vinayagam A.

Methods Mol Biol. 2017;1558:321-332. doi: 10.1007/978-1-4939-6783-4_15.

PMID:
28150245
12.

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca(2+) channel-vesicle coupling.

Böhme MA, Beis C, Reddy-Alla S, Reynolds E, Mampell MM, Grasskamp AT, Lützkendorf J, Bergeron DD, Driller JH, Babikir H, Göttfert F, Robinson IM, O'Kane CJ, Hell SW, Wahl MC, Stelzl U, Loll B, Walter AM, Sigrist SJ.

Nat Neurosci. 2016 Oct;19(10):1311-20. doi: 10.1038/nn.4364. Epub 2016 Aug 15.

PMID:
27526206
13.

Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.

Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7786-91. doi: 10.1073/pnas.1608061113. Epub 2016 Jun 28.

14.

Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex.

Apelt L, Knockenhauer KE, Leksa NC, Benlasfer N, Schwartz TU, Stelzl U.

Mol Cell Proteomics. 2016 Aug;15(8):2594-606. doi: 10.1074/mcp.M115.054627. Epub 2016 May 18.

15.

Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity.

Weir ME, Mann JE, Corwin T, Fulton ZW, Hao JM, Maniscalco JF, Kenney MC, Roman Roque KM, Chapdelaine EF, Stelzl U, Deming PB, Ballif BA, Hinkle KL.

FEBS Lett. 2016 Apr;590(8):1042-52. doi: 10.1002/1873-3468.12144. Epub 2016 Apr 13.

16.

Multiple protein-protein interactions converging on the Prp38 protein during activation of the human spliceosome.

Schütze T, Ulrich AK, Apelt L, Will CL, Bartlick N, Seeger M, Weber G, Lührmann R, Stelzl U, Wahl MC.

RNA. 2016 Feb;22(2):265-77. doi: 10.1261/rna.054296.115. Epub 2015 Dec 16.

17.

A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.

Absmeier E, Rosenberger L, Apelt L, Becke C, Santos KF, Stelzl U, Wahl MC.

Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):762-71. doi: 10.1107/S1399004715001005. Epub 2015 Mar 26.

PMID:
25849387
18.

Phospho-tyrosine dependent protein-protein interaction network.

Grossmann A, Benlasfer N, Birth P, Hegele A, Wachsmuth F, Apelt L, Stelzl U.

Mol Syst Biol. 2015 Mar 26;11(3):794. doi: 10.15252/msb.20145968.

19.

E. coli network upgrade.

Stelzl U.

Nat Biotechnol. 2014 Mar;32(3):241-3. doi: 10.1038/nbt.2848. No abstract available.

PMID:
24727776
20.

Studying post-translational modifications with protein interaction networks.

Woodsmith J, Stelzl U.

Curr Opin Struct Biol. 2014 Feb;24:34-44. doi: 10.1016/j.sbi.2013.11.009. Epub 2013 Dec 21. Review.

PMID:
24721451
21.

Molecular interaction networks in the analyses of sequence variation and proteomics data.

Stelzl U.

Proteomics Clin Appl. 2013 Dec;7(11-12):727-32. doi: 10.1002/prca.201300039. Epub 2013 Oct 29.

PMID:
24039079
22.

Dual coordination of post translational modifications in human protein networks.

Woodsmith J, Kamburov A, Stelzl U.

PLoS Comput Biol. 2013;9(3):e1002933. doi: 10.1371/journal.pcbi.1002933. Epub 2013 Mar 7.

23.

A Y2H-seq approach defines the human protein methyltransferase interactome.

Weimann M, Grossmann A, Woodsmith J, Özkan Z, Birth P, Meierhofer D, Benlasfer N, Valovka T, Timmermann B, Wanker EE, Sauer S, Stelzl U.

Nat Methods. 2013 Apr;10(4):339-42. doi: 10.1038/nmeth.2397. Epub 2013 Mar 3.

PMID:
23455924
24.

The ConsensusPathDB interaction database: 2013 update.

Kamburov A, Stelzl U, Lehrach H, Herwig R.

Nucleic Acids Res. 2013 Jan;41(Database issue):D793-800. doi: 10.1093/nar/gks1055. Epub 2012 Nov 11.

25.

Cluster-based assessment of protein-protein interaction confidence.

Kamburov A, Grossmann A, Herwig R, Stelzl U.

BMC Bioinformatics. 2012 Oct 10;13:262. doi: 10.1186/1471-2105-13-262.

26.

A computational framework for boosting confidence in high-throughput protein-protein interaction datasets.

Hosur R, Peng J, Vinayagam A, Stelzl U, Xu J, Perrimon N, Bienkowska J, Berger B.

Genome Biol. 2012 Aug 31;13(8):R76. doi: 10.1186/gb-2012-13-8-r76.

27.

IntScore: a web tool for confidence scoring of biological interactions.

Kamburov A, Stelzl U, Herwig R.

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W140-6. doi: 10.1093/nar/gks492. Epub 2012 May 30.

28.

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.

Chua JJ, Butkevich E, Worseck JM, Kittelmann M, Grønborg M, Behrmann E, Stelzl U, Pavlos NJ, Lalowski MM, Eimer S, Wanker EE, Klopfenstein DR, Jahn R.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5862-7. doi: 10.1073/pnas.1113819109. Epub 2012 Mar 26.

29.

Dynamic protein-protein interaction wiring of the human spliceosome.

Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Lührmann R, Stelzl U.

Mol Cell. 2012 Feb 24;45(4):567-80. doi: 10.1016/j.molcel.2011.12.034.

30.

A stringent yeast two-hybrid matrix screening approach for protein-protein interaction discovery.

Worseck JM, Grossmann A, Weimann M, Hegele A, Stelzl U.

Methods Mol Biol. 2012;812:63-87. doi: 10.1007/978-1-61779-455-1_4.

PMID:
22218854
31.

A directed protein interaction network for investigating intracellular signal transduction.

Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE.

Sci Signal. 2011 Sep 6;4(189):rs8. doi: 10.1126/scisignal.2001699.

32.

Large-scale de novo prediction of physical protein-protein association.

Elefsinioti A, Saraç ÖS, Hegele A, Plake C, Hubner NC, Poser I, Sarov M, Hyman A, Mann M, Schroeder M, Stelzl U, Beyer A.

Mol Cell Proteomics. 2011 Nov;10(11):M111.010629. doi: 10.1074/mcp.M111.010629. Epub 2011 Aug 11.

33.

Interactome mapping suggests new mechanistic details underlying Alzheimer's disease.

Soler-López M, Zanzoni A, Lluís R, Stelzl U, Aloy P.

Genome Res. 2011 Mar;21(3):364-76. doi: 10.1101/gr.114280.110. Epub 2010 Dec 16.

34.

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.

Sylvester M, Kliche S, Lange S, Geithner S, Klemm C, Schlosser A, Grossmann A, Stelzl U, Schraven B, Krause E, Freund C.

PLoS One. 2010 Jul 22;5(7):e11708. doi: 10.1371/journal.pone.0011708. Erratum in: PLoS One. 2010;5(8). doi. 10.1371/annotation/84d00e99-8566-4e44-b68f-a8d5b46db459.

35.

Detection of alpha-rod protein repeats using a neural network and application to huntingtin.

Palidwor GA, Shcherbinin S, Huska MR, Rasko T, Stelzl U, Arumughan A, Foulle R, Porras P, Sanchez-Pulido L, Wanker EE, Andrade-Navarro MA.

PLoS Comput Biol. 2009 Mar;5(3):e1000304. doi: 10.1371/journal.pcbi.1000304. Epub 2009 Mar 13.

36.

An empirical framework for binary interactome mapping.

Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, Cevik S, Simon C, de Smet AS, Dann E, Smolyar A, Vinayagam A, Yu H, Szeto D, Borick H, Dricot A, Klitgord N, Murray RR, Lin C, Lalowski M, Timm J, Rau K, Boone C, Braun P, Cusick ME, Roth FP, Hill DE, Tavernier J, Wanker EE, Barabási AL, Vidal M.

Nat Methods. 2009 Jan;6(1):83-90. doi: 10.1038/nmeth.1280. Epub 2008 Dec 7.

37.

In vitro selection of random RNA fragments to identify protein-binding sites within large RNAs.

Stelzl U, Nierhaus KH.

Methods Mol Biol. 2008;488:247-55. doi: 10.1007/978-1-60327-475-3_17.

PMID:
18982296
38.

Characterization of RNA-protein interactions by phosphorothioate footprinting and its applications to the ribosome.

Ozlem Tastan Bishop A, Stelzl U, Pech M, Nierhaus KH.

Methods Mol Biol. 2008;488:129-51. doi: 10.1007/978-1-60327-475-3_9.

PMID:
18982288
39.
40.

The value of high quality protein-protein interaction networks for systems biology.

Stelzl U, Wanker EE.

Curr Opin Chem Biol. 2006 Dec;10(6):551-8. Epub 2006 Oct 19. Review.

PMID:
17055769
41.

Huntingtin interacts with the receptor sorting family protein GASP2.

Horn SC, Lalowski M, Goehler H, Dröge A, Wanker EE, Stelzl U.

J Neural Transm (Vienna). 2006 Aug;113(8):1081-90. Epub 2006 Jul 13.

PMID:
16835690
42.

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.

Grelle G, Kostka S, Otto A, Kersten B, Genser KF, Müller EC, Wälter S, Böddrich A, Stelzl U, Hänig C, Volkmer-Engert R, Landgraf C, Alberti S, Höhfeld J, Strödicke M, Wanker EE.

Mol Cell Proteomics. 2006 Feb;5(2):234-44. Epub 2005 Nov 7.

43.

A human protein-protein interaction network: a resource for annotating the proteome.

Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE.

Cell. 2005 Sep 23;122(6):957-68.

44.

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.

Goehler H, Lalowski M, Stelzl U, Waelter S, Stroedicke M, Worm U, Droege A, Lindenberg KS, Knoblich M, Haenig C, Herbst M, Suopanki J, Scherzinger E, Abraham C, Bauer B, Hasenbank R, Fritzsche A, Ludewig AH, Büssow K, Coleman SH, Gutekunst CA, Landwehrmeyer BG, Lehrach H, Wanker EE.

Mol Cell. 2004 Sep 24;15(6):853-65. Erratum in: Mol Cell. 2005 Jul 22;19(2):287. Buessow, Konrad [corrected to Büssow, Konrad].

45.

Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.

Blume A, Weidemann W, Stelzl U, Wanker EE, Lucka L, Donner P, Reutter W, Horstkorte R, Hinderlich S.

Biochem J. 2004 Dec 15;384(Pt 3):599-607.

46.

RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon.

Stelzl U, Zengel JM, Tovbina M, Walker M, Nierhaus KH, Lindahl L, Patel DJ.

J Biol Chem. 2003 Jul 25;278(30):28237-45. Epub 2003 May 8.

47.

Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome.

Wilson DN, Blaha G, Connell SR, Ivanov PV, Jenke H, Stelzl U, Teraoka Y, Nierhaus KH.

Curr Protein Pept Sci. 2002 Feb;3(1):1-53. Review.

PMID:
12370010
48.

The tetracycline resistance protein Tet(o) perturbs the conformation of the ribosomal decoding centre.

Connell SR, Trieber CA, Stelzl U, Einfeldt E, Taylor DE, Nierhaus KH.

Mol Microbiol. 2002 Sep;45(6):1463-72.

49.

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