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Items: 1 to 50 of 160

1.

Some Preformulation Studies of Pyruvic Acid and Other α-Keto Carboxylic Acids in Aqueous Solution: Pharmaceutical Formulation Implications for These Peroxide Scavengers.

Lopalco A, Deeken R, Douglas J, Denora N, Stella VJ.

J Pharm Sci. 2019 Oct;108(10):3281-3288. doi: 10.1016/j.xphs.2019.05.030. Epub 2019 Jun 1.

PMID:
31163186
2.

Origins, and formulation implications, of the pKa difference between boronic acids and their esters: A density functional theory study.

Lopalco A, Stella VJ, Thompson WH.

Eur J Pharm Sci. 2018 Nov 1;124:10-16. doi: 10.1016/j.ejps.2018.08.017. Epub 2018 Aug 14.

PMID:
30118849
3.

Novel prodrug PRX-P4-003, selectively activated by gut enzymes, may reduce the risk of iatrogenic addiction and abuse.

Patil ST, Bihovsky RH, Smith SA, Potter WZ, Stella VJ.

Drug Alcohol Depend. 2018 May 1;186:159-166. doi: 10.1016/j.drugalcdep.2017.12.042. Epub 2018 Mar 2.

PMID:
29574296
4.

Mechanism of Degradation of an α-Keto-Epoxide, a Model for the Warhead for Various Proteasome Inhibitor Anticancer Agents.

Phizackerley KM, Jumaa M, Lopalco A, Wolfe BH, Ablan CD, Stella VJ.

J Pharm Sci. 2017 Apr;106(4):1051-1061. doi: 10.1016/j.xphs.2016.12.006. Epub 2016 Dec 20.

PMID:
28007565
5.

Isolation, Solubility, and Characterization of D-Mannitol Esters of 4-Methoxybenzeneboronic Acid.

Lopalco A, Marinaro WA, Day VW, Stella VJ.

J Pharm Sci. 2017 Feb;106(2):601-610. doi: 10.1016/j.xphs.2016.10.022. Epub 2016 Dec 6.

PMID:
27938893
6.

Effect of Molecular Structure on the Relative Hydrogen Peroxide Scavenging Ability of Some α-Keto Carboxylic Acids.

Lopalco A, Stella VJ.

J Pharm Sci. 2016 Sep;105(9):2879-2885. doi: 10.1016/j.xphs.2016.03.041. Epub 2016 May 18.

PMID:
27209460
7.

Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide.

Lopalco A, Dalwadi G, Niu S, Schowen RL, Douglas J, Stella VJ.

J Pharm Sci. 2016 Feb;105(2):705-713. doi: 10.1002/jps.24653. Epub 2016 Jan 29.

8.

Determination of pKa and Hydration Constants for a Series of α-Keto-Carboxylic Acids Using Nuclear Magnetic Resonance Spectrometry.

Lopalco A, Douglas J, Denora N, Stella VJ.

J Pharm Sci. 2016 Feb;105(2):664-672. doi: 10.1002/jps.24539. Epub 2016 Jan 29.

9.

Interaction of model aryl- and alkyl-boronic acids and 1,2-diols in aqueous solution.

Marinaro WA, Prankerd R, Kinnari K, Stella VJ.

J Pharm Sci. 2015 Apr;104(4):1399-408. doi: 10.1002/jps.24346. Epub 2015 Jan 19.

PMID:
25600471
10.

Targeted delivery of a model immunomodulator to the lymphatic system: comparison of alkyl ester versus triglyceride mimetic lipid prodrug strategies.

Han S, Quach T, Hu L, Wahab A, Charman WN, Stella VJ, Trevaskis NL, Simpson JS, Porter CJ.

J Control Release. 2014 Mar 10;177:1-10. doi: 10.1016/j.jconrel.2013.12.031. Epub 2014 Jan 5.

PMID:
24398334
11.

Hydrolysis of the quinone methide of butylated hydroxytoluene in aqueous solutions.

Willcockson MG, Toteva MM, Stella VJ.

J Pharm Sci. 2013 Oct;102(10):3579-85. doi: 10.1002/jps.23657. Epub 2013 Jul 19.

PMID:
23873381
12.

Chemical drug stability in lipids, modified lipids, and polyethylene oxide-containing formulations.

Stella VJ.

Pharm Res. 2013 Dec;30(12):3018-28. doi: 10.1007/s11095-013-1051-2. Epub 2013 May 2.

PMID:
23636838
13.

Dissolution of weak acids under laminar flow and rotating disk hydrodynamic conditions: application of a comprehensive convection-diffusion-migration-reaction transport model.

Neervannan S, Southard MZ, Stella VJ.

J Pharm Sci. 2012 Sep;101(9):3180-9. doi: 10.1002/jps.23209. Epub 2012 May 23.

PMID:
22623113
14.

Properties of a model aryl boronic acid and its boroxine.

Marinaro WA, Schieber LJ, Munson EJ, Day VW, Stella VJ.

J Pharm Sci. 2012 Sep;101(9):3190-8. doi: 10.1002/jps.23207. Epub 2012 May 21.

PMID:
22614918
15.

Determination of the permeability characteristics of two sulfenamide prodrugs of linezolid across Caco-2 cells.

Nti-Addae KW, Guarino VR, Dalwadi G, Stella VJ.

J Pharm Sci. 2012 Sep;101(9):3134-41. doi: 10.1002/jps.23084. Epub 2012 Feb 28.

PMID:
22374830
16.

Reversion of sulfenamide prodrugs in the presence of free thiol-containing proteins.

Nti-Addae KW, Laurence JS, Skinner AL, Stella VJ.

J Pharm Sci. 2011 Jul;100(7):3023-7. doi: 10.1002/jps.22505. Epub 2011 Feb 3.

17.
18.

Design of tablets for the delayed and complete release of poorly water-soluble weak base drugs using SBE7M-β-CD as a solubilizing agent.

Rao VM, Zannou EA, Stella VJ.

J Pharm Sci. 2011 Apr;100(4):1576-87. doi: 10.1002/jps.22375. Epub 2010 Dec 1.

PMID:
24081477
19.

MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids.

Guarino VR, Nti-Addae K, Stella VJ.

Bioorg Med Chem Lett. 2011 Jan 1;21(1):172-5. doi: 10.1016/j.bmcl.2010.11.043. Epub 2010 Nov 11.

PMID:
21126873
20.

In vitro conversion of model sulfenamide prodrugs in the presence of small molecule thiols.

Nti-Addae KW, Stella VJ.

J Pharm Sci. 2011 Mar;100(3):1001-8. doi: 10.1002/jps.22347. Epub 2010 Oct 18.

PMID:
20957747
21.

In vitro and in vivo evaluation of a novel water-soluble N-glycyl prodrug (N-GLY-CBZ) of carbamazepine.

Hemenway JN, Stella VJ.

J Pharm Sci. 2010 Nov;99(11):4565-75. doi: 10.1002/jps.22171.

PMID:
20845455
22.

Prodrugs: Some thoughts and current issues.

Stella VJ.

J Pharm Sci. 2010 Dec;99(12):4755-65. doi: 10.1002/jps.22205. Erratum in: J Pharm Sci. 2011 Oct;100(10):4560.

PMID:
20821387
24.

Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.

Hemenway JN, Jarho P, Henri JT, Nair SK, VanderVelde D, Georg GI, Stella VJ.

J Pharm Sci. 2010 Apr;99(4):1810-25. doi: 10.1002/jps.21952.

PMID:
19774656
25.
26.

Sulfobutyl ether-alkyl ether mixed cyclodextrin derivatives with enhanced inclusion ability.

Tongiani S, Ozeki T, Stella VJ.

J Pharm Sci. 2009 Dec;98(12):4769-80. doi: 10.1002/jps.21791.

PMID:
19408308
27.
29.

Cyclodextrins.

Stella VJ, He Q.

Toxicol Pathol. 2008 Jan;36(1):30-42. doi: 10.1177/0192623307310945. Review.

PMID:
18337219
30.

Your prodrug releases formaldehyde: should you be concerned? No!

Dhareshwar SS, Stella VJ.

J Pharm Sci. 2008 Oct;97(10):4184-93. doi: 10.1002/jps.21319.

PMID:
18288723
32.

Preparation, characterization and in vivo conversion of new water-soluble sulfenamide prodrugs of carbamazepine.

Hemenway JN, Nti-Addae K, Guarino VR, Stella VJ.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6629-32. Epub 2007 Sep 15.

PMID:
17928225
33.

Degradation of paclitaxel and related compounds in aqueous solutions I: epimerization.

Tian J, Stella VJ.

J Pharm Sci. 2008 Mar;97(3):1224-35.

PMID:
17680660
34.

Prodrug strategies to overcome poor water solubility.

Stella VJ, Nti-Addae KW.

Adv Drug Deliv Rev. 2007 Jul 30;59(7):677-94. Epub 2007 May 29. Review.

PMID:
17628203
35.

Sulfenamides as prodrugs of NH-acidic compounds: a new prodrug option for the amide bond.

Guarino VR, Karunaratne V, Stella VJ.

Bioorg Med Chem Lett. 2007 Sep 1;17(17):4910-3. Epub 2007 Jun 13.

PMID:
17604170
36.
38.

Characterization of prednisolone in controlled porosity osmotic pump pellets using solid-state NMR spectroscopy.

Sotthivirat S, Lubach JW, Haslam JL, Munson EJ, Stella VJ.

J Pharm Sci. 2007 May;96(5):1008-17.

PMID:
17455361
39.

Evaluation of various properties of alternative salt forms of sulfobutylether-beta-cyclodextrin, (SBE)7M-beta-CD.

Sotthivirat S, Haslam JL, Stella VJ.

Int J Pharm. 2007 Feb 7;330(1-2):73-81. Epub 2006 Sep 16.

PMID:
17045435
40.
41.

Phase solubility and structure of the inclusion complexes of prednisolone and 6 alpha-methyl prednisolone with various cyclodextrins.

Larsen KL, Aachmann FL, Wimmer R, Stella VJ, Kjølner UM.

J Pharm Sci. 2005 Mar;94(3):507-15.

PMID:
15627254
42.

Applicability of (SBE)7m-beta-CD in controlled-porosity osmotic pump tablets (OPTs).

Okimoto K, Tokunaga Y, Ibuki R, Irie T, Uekama K, Rajewski RA, Stella VJ.

Int J Pharm. 2004 Nov 22;286(1-2):81-8.

PMID:
15501004
43.

Kinetics and mechanism of degradation of epothilone-D: an experimental anticancer agent.

Jumaa M, Carlson B, Chimilio L, Silchenko S, Stella VJ.

J Pharm Sci. 2004 Dec;93(12):2953-61.

PMID:
15459947
45.

Photostability of 2-hydroxymethyl-4,8-dibenzo[1,2-b:5,4-b']dithiophene-4,8-dione (NSC 656240), a potential anticancer drug.

Silchenko S, Schöneich C, Carlson BJ, Stella VJ.

Int J Pharm. 2003 Oct 2;264(1-2):97-105.

PMID:
12972339
46.
47.

When can cyclodextrins be considered for solubilization purposes?

Rao VM, Stella VJ.

J Pharm Sci. 2003 May;92(5):927-32.

PMID:
12712411
48.

Osmotic properties of sulfobutylether and hydroxypropyl cyclodextrins.

Zannou EA, Streng WH, Stella VJ.

Pharm Res. 2001 Aug;18(8):1226-31.

PMID:
11587496
49.

My mentors.

Stella VJ.

J Pharm Sci. 2001 Aug;90(8):969-78.

PMID:
11536200
50.

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