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Items: 1 to 50 of 68

1.

[Lupus nephritis].

Melderis S, Wiech T, Iking-Konert C, Steinmetz OM.

Z Rheumatol. 2018 Jun 28. doi: 10.1007/s00393-018-0496-4. [Epub ahead of print] German.

PMID:
29955955
2.

IL-10 Receptor Signaling Empowers Regulatory T Cells to Control Th17 Responses and Protect from GN.

Diefenhardt P, Nosko A, Kluger MA, Richter JV, Wegscheid C, Kobayashi Y, Tiegs G, Huber S, Flavell RA, Stahl RAK, Steinmetz OM.

J Am Soc Nephrol. 2018 Jul;29(7):1825-1837. doi: 10.1681/ASN.2017091044. Epub 2018 Jun 4.

PMID:
29866800
3.

IL-17C/IL-17 Receptor E Signaling in CD4+ T Cells Promotes TH17 Cell-Driven Glomerular Inflammation.

Krohn S, Nies JF, Kapffer S, Schmidt T, Riedel JH, Kaffke A, Peters A, Borchers A, Steinmetz OM, Krebs CF, Turner JE, Brix SR, Paust HJ, Stahl RAK, Panzer U.

J Am Soc Nephrol. 2018 Apr;29(4):1210-1222. doi: 10.1681/ASN.2017090949. Epub 2018 Feb 26.

PMID:
29483158
4.

Organisation of lymphocytic infiltrates in ANCA-associated glomerulonephritis.

Brix SR, Noriega M, Herden EM, Goldmann B, Langbehn U, Busch M, Jabs WJ, Steinmetz OM, Panzer U, Huber TB, Stahl RAK, Wiech T.

Histopathology. 2018 Jun;72(7):1093-1101. doi: 10.1111/his.13487. Epub 2018 Mar 25.

PMID:
29453894
5.

Population pharmacokinetics and dosing simulations of ceftazidime in critically ill patients receiving sustained low-efficiency dialysis.

König C, Braune S, Roberts JA, Nierhaus A, Steinmetz OM, Baehr M, Frey OR, Langebrake C, Kluge S.

J Antimicrob Chemother. 2017 May 1;72(5):1433-1440. doi: 10.1093/jac/dkw592.

PMID:
28175308
6.

[Acute renal failure in a 75-year-old woman with a high-output ileostoma].

Teege S, Wiech T, Steinmetz OM.

Internist (Berl). 2017 May;58(5):507-511. doi: 10.1007/s00108-016-0175-y. German.

PMID:
28084501
7.

CD4+ T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes.

Krebs CF, Steinmetz OM.

Mediators Inflamm. 2016;2016:5393894. Epub 2016 Nov 15. Review.

8.

RORγt expression in Tregs promotes systemic lupus erythematosus via IL-17 secretion, alteration of Treg phenotype and suppression of Th2 responses.

Kluger MA, Nosko A, Ramcke T, Goerke B, Meyer MC, Wegscheid C, Luig M, Tiegs G, Stahl RA, Steinmetz OM.

Clin Exp Immunol. 2017 Apr;188(1):63-78. doi: 10.1111/cei.12905. Epub 2017 Jan 5.

9.

Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney.

Krebs CF, Paust HJ, Krohn S, Koyro T, Brix SR, Riedel JH, Bartsch P, Wiech T, Meyer-Schwesinger C, Huang J, Fischer N, Busch P, Mittrücker HW, Steinhoff U, Stockinger B, Perez LG, Wenzel UO, Janneck M, Steinmetz OM, Gagliani N, Stahl RAK, Huber S, Turner JE, Panzer U.

Immunity. 2016 Nov 15;45(5):1078-1092. doi: 10.1016/j.immuni.2016.10.020.

10.

The Authors Reply.

Kluger MA, Melderis S, Steinmetz OM.

Kidney Int. 2016 Jul;90(1):222-3. doi: 10.1016/j.kint.2016.03.011. No abstract available.

PMID:
27312447
11.

T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN.

Nosko A, Kluger MA, Diefenhardt P, Melderis S, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2017 Jan;28(1):185-196. doi: 10.1681/ASN.2015070820. Epub 2016 Jun 13.

12.

Plasticity of Th17 Cells in Autoimmune Kidney Diseases.

Krebs CF, Turner JE, Paust HJ, Kapffer S, Koyro T, Krohn S, Ufer F, Friese MA, Flavell RA, Stockinger B, Steinmetz OM, Stahl RA, Huber S, Panzer U.

J Immunol. 2016 Jul 15;197(2):449-57. doi: 10.4049/jimmunol.1501831. Epub 2016 Jun 6.

13.

A Mechanism for Cancer-Associated Membranous Nephropathy.

Hoxha E, Wiech T, Stahl PR, Zahner G, Tomas NM, Meyer-Schwesinger C, Wenzel U, Janneck M, Steinmetz OM, Panzer U, Harendza S, Stahl RA.

N Engl J Med. 2016 May 19;374(20):1995-6. doi: 10.1056/NEJMc1511702. No abstract available.

14.

IL-17F Promotes Tissue Injury in Autoimmune Kidney Diseases.

Riedel JH, Paust HJ, Krohn S, Turner JE, Kluger MA, Steinmetz OM, Krebs CF, Stahl RA, Panzer U.

J Am Soc Nephrol. 2016 Dec;27(12):3666-3677. Epub 2016 Mar 30.

15.

CXCR3+ Regulatory T Cells Control TH1 Responses in Crescentic GN.

Paust HJ, Riedel JH, Krebs CF, Turner JE, Brix SR, Krohn S, Velden J, Wiech T, Kaffke A, Peters A, Bennstein SB, Kapffer S, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Thaiss F, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U.

J Am Soc Nephrol. 2016 Jul;27(7):1933-42. doi: 10.1681/ASN.2015020203. Epub 2015 Nov 3.

16.

Treg17 cells are programmed by Stat3 to suppress Th17 responses in systemic lupus.

Kluger MA, Melderis S, Nosko A, Goerke B, Luig M, Meyer MC, Turner JE, Meyer-Schwesinger C, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

Kidney Int. 2016 Jan;89(1):158-66. doi: 10.1038/ki.2015.296. Epub 2016 Jan 4.

PMID:
26466322
17.

RORγt(+)Foxp3(+) Cells are an Independent Bifunctional Regulatory T Cell Lineage and Mediate Crescentic GN.

Kluger MA, Meyer MC, Nosko A, Goerke B, Luig M, Wegscheid C, Tiegs G, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2016 Feb;27(2):454-65. doi: 10.1681/ASN.2014090880. Epub 2015 Jun 8.

18.

Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN.

Luig M, Kluger MA, Goerke B, Meyer M, Nosko A, Yan I, Scheller J, Mittrücker HW, Rose-John S, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2015 Jul;26(7):1597-607. doi: 10.1681/ASN.2014060620. Epub 2015 Feb 5.

19.

Function of the Th17/interleukin-17A immune response in murine lupus nephritis.

Schmidt T, Paust HJ, Krebs CF, Turner JE, Kaffke A, Bennstein SB, Koyro T, Peters A, Velden J, Hünemörder S, Haag F, Steinmetz OM, Mittrücker HW, Stahl RA, Panzer U.

Arthritis Rheumatol. 2015 Feb;67(2):475-87. doi: 10.1002/art.38955.

20.

CXCL5 drives neutrophil recruitment in TH17-mediated GN.

Disteldorf EM, Krebs CF, Paust HJ, Turner JE, Nouailles G, Tittel A, Meyer-Schwesinger C, Stege G, Brix S, Velden J, Wiech T, Helmchen U, Steinmetz OM, Peters A, Bennstein SB, Kaffke A, Llanto C, Lira SA, Mittrücker HW, Stahl RA, Kurts C, Kaufmann SH, Panzer U.

J Am Soc Nephrol. 2015 Jan;26(1):55-66. doi: 10.1681/ASN.2013101061. Epub 2014 Jun 5.

21.

Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.

Chan AJ, Alikhan MA, Odobasic D, Gan PY, Khouri MB, Steinmetz OM, Mansell AS, Kitching AR, Holdsworth SR, Summers SA.

Am J Pathol. 2014 May;184(5):1411-8. doi: 10.1016/j.ajpath.2014.01.023. Epub 2014 Mar 14.

22.

Endogenous interleukin (IL)-17A promotes pristane-induced systemic autoimmunity and lupus nephritis induced by pristane.

Summers SA, Odobasic D, Khouri MB, Steinmetz OM, Yang Y, Holdsworth SR, Kitching AR.

Clin Exp Immunol. 2014 Jun;176(3):341-50. doi: 10.1111/cei.12287.

23.

Stat3 programs Th17-specific regulatory T cells to control GN.

Kluger MA, Luig M, Wegscheid C, Goerke B, Paust HJ, Brix SR, Yan I, Mittrücker HW, Hagl B, Renner ED, Tiegs G, Wiech T, Stahl RA, Panzer U, Steinmetz OM.

J Am Soc Nephrol. 2014 Jun;25(6):1291-302. doi: 10.1681/ASN.2013080904. Epub 2014 Feb 7.

24.

B-cell-derived IL-10 does not vitally contribute to the clinical course of glomerulonephritis.

Kluger MA, Ostmann A, Luig M, Meyer MC, Goerke B, Paust HJ, Meyer-Schwesinger C, Stahl RA, Panzer U, Tiegs G, Steinmetz OM.

Eur J Immunol. 2014 Mar;44(3):683-93. doi: 10.1002/eji.201343842. Epub 2013 Dec 16.

25.

MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.

Krebs CF, Kapffer S, Paust HJ, Schmidt T, Bennstein SB, Peters A, Stege G, Brix SR, Meyer-Schwesinger C, Müller RU, Turner JE, Steinmetz OM, Wolf G, Stahl RA, Panzer U.

J Am Soc Nephrol. 2013 Dec;24(12):1955-65. doi: 10.1681/ASN.2013020130. Epub 2013 Aug 15.

26.

Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses.

Hirota K, Turner JE, Villa M, Duarte JH, Demengeot J, Steinmetz OM, Stockinger B.

Nat Immunol. 2013 Apr;14(4):372-9. doi: 10.1038/ni.2552. Epub 2013 Mar 10.

27.

IL-6 controls the innate immune response against Listeria monocytogenes via classical IL-6 signaling.

Hoge J, Yan I, Jänner N, Schumacher V, Chalaris A, Steinmetz OM, Engel DR, Scheller J, Rose-John S, Mittrücker HW.

J Immunol. 2013 Jan 15;190(2):703-11. doi: 10.4049/jimmunol.1201044. Epub 2012 Dec 12.

28.

Immature renal dendritic cells recruit regulatory CXCR6(+) invariant natural killer T cells to attenuate crescentic GN.

Riedel JH, Paust HJ, Turner JE, Tittel AP, Krebs C, Disteldorf E, Wegscheid C, Tiegs G, Velden J, Mittrücker HW, Garbi N, Stahl RA, Steinmetz OM, Kurts C, Panzer U.

J Am Soc Nephrol. 2012 Dec;23(12):1987-2000. doi: 10.1681/ASN.2012040394. Epub 2012 Nov 8.

29.

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.

Turner JE, Krebs C, Tittel AP, Paust HJ, Meyer-Schwesinger C, Bennstein SB, Steinmetz OM, Prinz I, Magnus T, Korn T, Stahl RA, Kurts C, Panzer U.

J Am Soc Nephrol. 2012 Sep;23(9):1486-95. doi: 10.1681/ASN.2012010040. Epub 2012 Jul 12.

30.

Chemokines play a critical role in the cross-regulation of Th1 and Th17 immune responses in murine crescentic glomerulonephritis.

Paust HJ, Turner JE, Riedel JH, Disteldorf E, Peters A, Schmidt T, Krebs C, Velden J, Mittrücker HW, Steinmetz OM, Stahl RA, Panzer U.

Kidney Int. 2012 Jul;82(1):72-83. doi: 10.1038/ki.2012.101. Epub 2012 Apr 11.

31.

Protective role for CCR5 in murine lupus nephritis.

Turner JE, Paust HJ, Bennstein SB, Bramke P, Krebs C, Steinmetz OM, Velden J, Haag F, Stahl RA, Panzer U.

Am J Physiol Renal Physiol. 2012 Jun 1;302(11):F1503-15. doi: 10.1152/ajprenal.00382.2011. Epub 2012 Mar 21.

32.

Renal IL-17 expression in human ANCA-associated glomerulonephritis.

Velden J, Paust HJ, Hoxha E, Turner JE, Steinmetz OM, Wolf G, Jabs WJ, Özcan F, Beige J, Heering PJ, Schröder S, Kneißler U, Disteldorf E, Mittrücker HW, Stahl RA, Helmchen U, Panzer U.

Am J Physiol Renal Physiol. 2012 Jun 15;302(12):F1663-73. doi: 10.1152/ajprenal.00683.2011. Epub 2012 Mar 21.

33.

Mast cells mediate acute kidney injury through the production of TNF.

Summers SA, Chan J, Gan PY, Dewage L, Nozaki Y, Steinmetz OM, Nikolic-Paterson DJ, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2011 Dec;22(12):2226-36. doi: 10.1681/ASN.2011020182. Epub 2011 Oct 21.

34.

ISN Forefronts Symposium 2010 in Sylt, Germany: 'Induction and Resolution of Renal Inflammation'.

Panzer U, Turner JE, Steinmetz OM, Kurts C, Johnson RJ, Stahl RA.

Kidney Int. 2011 Apr;79(8):807-13. doi: 10.1038/ki.2010.560. Epub 2011 Feb 2.

35.

Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis.

Summers SA, Steinmetz OM, Gan PY, Ooi JD, Odobasic D, Kitching AR, Holdsworth SR.

Arthritis Rheum. 2011 Apr;63(4):1124-35. doi: 10.1002/art.30208.

36.

The Th17-defining transcription factor RORγt promotes glomerulonephritis.

Steinmetz OM, Summers SA, Gan PY, Semple T, Holdsworth SR, Kitching AR.

J Am Soc Nephrol. 2011 Mar;22(3):472-83. doi: 10.1681/ASN.2010040435. Epub 2010 Dec 23.

37.

Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis.

Summers SA, Steinmetz OM, Ooi JD, Gan PY, O'Sullivan KM, Visvanathan K, Akira S, Kitching AR, Holdsworth SR.

Am J Pathol. 2010 Nov;177(5):2234-44. doi: 10.2353/ajpath.2010.100153. Epub 2010 Sep 16.

38.

TLR9 and TLR4 are required for the development of autoimmunity and lupus nephritis in pristane nephropathy.

Summers SA, Hoi A, Steinmetz OM, O'Sullivan KM, Ooi JD, Odobasic D, Akira S, Kitching AR, Holdsworth SR.

J Autoimmun. 2010 Dec;35(4):291-8. doi: 10.1016/j.jaut.2010.05.004.

PMID:
20810248
39.

The Th17 immune response in renal inflammation.

Turner JE, Paust HJ, Steinmetz OM, Panzer U.

Kidney Int. 2010 Jun;77(12):1070-5. doi: 10.1038/ki.2010.102. Epub 2010 Apr 14. Review.

40.

Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis.

Gan PY, Steinmetz OM, Tan DS, O'Sullivan KM, Ooi JD, Iwakura Y, Kitching AR, Holdsworth SR.

J Am Soc Nephrol. 2010 Jun;21(6):925-31. doi: 10.1681/ASN.2009070763. Epub 2010 Mar 18.

41.

CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.

Turner JE, Paust HJ, Steinmetz OM, Peters A, Riedel JH, Erhardt A, Wegscheid C, Velden J, Fehr S, Mittrücker HW, Tiegs G, Stahl RA, Panzer U.

J Am Soc Nephrol. 2010 Jun;21(6):974-85. doi: 10.1681/ASN.2009070741. Epub 2010 Mar 18.

42.

Staying on top of things right from the start: the obsessive-compulsive disorder of regulatory T cells.

Steinmetz OM, Turner JE, Panzer U.

J Am Soc Nephrol. 2010 Jan;21(1):6-7. doi: 10.1681/ASN.2009111140. Epub 2009 Dec 3. No abstract available.

43.

Th1 and Th17 cells induce proliferative glomerulonephritis.

Summers SA, Steinmetz OM, Li M, Kausman JY, Semple T, Edgtton KL, Borza DB, Braley H, Holdsworth SR, Kitching AR.

J Am Soc Nephrol. 2009 Dec;20(12):2518-24. doi: 10.1681/ASN.2009030337. Epub 2009 Oct 9.

44.

CXCR3 mediates renal Th1 and Th17 immune response in murine lupus nephritis.

Steinmetz OM, Turner JE, Paust HJ, Lindner M, Peters A, Heiss K, Velden J, Hopfer H, Fehr S, Krieger T, Meyer-Schwesinger C, Meyer TN, Helmchen U, Mittrücker HW, Stahl RA, Panzer U.

J Immunol. 2009 Oct 1;183(7):4693-704. doi: 10.4049/jimmunol.0802626. Epub 2009 Sep 4.

45.

Chemokines and B cells in renal inflammation and allograft rejection.

Steinmetz OM, Stahl RA, Panzer U.

Front Biosci (Schol Ed). 2009 Jun 1;1:13-22. Review.

PMID:
19482678
46.

Resolution of renal inflammation: a new role for NF-kappaB1 (p50) in inflammatory kidney diseases.

Panzer U, Steinmetz OM, Turner JE, Meyer-Schwesinger C, von Ruffer C, Meyer TN, Zahner G, Gómez-Guerrero C, Schmid RM, Helmchen U, Moeckel GW, Wolf G, Stahl RA, Thaiss F.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F429-39. doi: 10.1152/ajprenal.90435.2008. Epub 2009 May 20.

47.

The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis.

Paust HJ, Turner JE, Steinmetz OM, Peters A, Heymann F, Hölscher C, Wolf G, Kurts C, Mittrücker HW, Stahl RA, Panzer U.

J Am Soc Nephrol. 2009 May;20(5):969-79. doi: 10.1681/ASN.2008050556. Epub 2009 Apr 1.

48.

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.

Benndorf RA, Krebs C, Hirsch-Hoffmann B, Schwedhelm E, Cieslar G, Schmidt-Haupt R, Steinmetz OM, Meyer-Schwesinger C, Thaiss F, Haddad M, Fehr S, Heilmann A, Helmchen U, Hein L, Ehmke H, Stahl RA, Böger RH, Wenzel UO.

Kidney Int. 2009 May;75(10):1039-49. doi: 10.1038/ki.2009.2. Epub 2009 Feb 11.

49.

CCR5 deficiency aggravates crescentic glomerulonephritis in mice.

Turner JE, Paust HJ, Steinmetz OM, Peters A, Meyer-Schwesinger C, Heymann F, Helmchen U, Fehr S, Horuk R, Wenzel U, Kurts C, Mittrücker HW, Stahl RA, Panzer U.

J Immunol. 2008 Nov 1;181(9):6546-56.

50.

15-deoxy-Delta12,14-prostaglandin J2 inhibits INF-gamma-induced JAK/STAT1 signalling pathway activation and IP-10/CXCL10 expression in mesangial cells.

Panzer U, Zahner G, Wienberg U, Steinmetz OM, Peters A, Turner JE, Paust HJ, Wolf G, Stahl RA, Schneider A.

Nephrol Dial Transplant. 2008 Dec;23(12):3776-85. doi: 10.1093/ndt/gfn361. Epub 2008 Jul 2.

PMID:
18596134

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