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Items: 1 to 50 of 98

1.

Melioidosis in Africa: Time to Uncover the True Disease Load.

Steinmetz I, Wagner GE, Kanyala E, Sawadogo M, Soumeya H, Teferi M, Andargie E, Yeshitela B, Yaba Atsé-Achi L, Sanogo M, Bonfoh B, Rakotozandrindrainy R, Pongombo Shongo C, Shongoya Pongombo M, Kasamba Ilunga E, Lichtenegger S, Assig K, May J, Bertherat E, Owusu M, Owusu-Dabo E, Adu-Sarkodie Y.

Trop Med Infect Dis. 2018 Jun 10;3(2). pii: E62. doi: 10.3390/tropicalmed3020062. Review.

2.

Melioidosis in Vietnam: Recently Improved Recognition but still an Uncertain Disease Burden after Almost a Century of Reporting.

Trinh TT, Nguyen LDN, Nguyen TV, Tran CX, Le AV, Nguyen HV, Assig K, Lichtenegger S, Wagner GE, Do CD, Steinmetz I.

Trop Med Infect Dis. 2018 Apr 9;3(2). pii: E39. doi: 10.3390/tropicalmed3020039. Review.

3.

Erratum to "Comparison of Oral Microbe Quantities from Tongue Samples and Subgingival Pockets".

Göhler A, Samietz S, Schmidt CO, Kocher T, Steinmetz I, Holtfreter B.

Int J Dent. 2018 Jul 19;2018:5615780. doi: 10.1155/2018/5615780. eCollection 2018.

4.

BRAF inhibitors stimulate inflammasome activation and interleukin 1 beta production in dendritic cells.

Hajek E, Krebs F, Bent R, Haas K, Bast A, Steinmetz I, Tuettenberg A, Grabbe S, Bros M.

Oncotarget. 2018 Jun 19;9(47):28294-28308. doi: 10.18632/oncotarget.25511. eCollection 2018 Jun 19.

5.

GvmR - A Novel LysR-Type Transcriptional Regulator Involved in Virulence and Primary and Secondary Metabolism of Burkholderia pseudomallei.

Duong LT, Schwarz S, Gross H, Breitbach K, Hochgräfe F, Mostertz J, Eske-Pogodda K, Wagner GE, Steinmetz I, Kohler C.

Front Microbiol. 2018 May 16;9:935. doi: 10.3389/fmicb.2018.00935. eCollection 2018.

6.

Comparison of Oral Microbe Quantities from Tongue Samples and Subgingival Pockets.

Göhler A, Samietz S, Schmidt CO, Kocher T, Steinmetz I, Holtfreter B.

Int J Dent. 2018 Apr 26;2018:2048390. doi: 10.1155/2018/2048390. eCollection 2018. Erratum in: Int J Dent. 2018 Jul 19;2018:5615780.

7.

Burkholderia pseudomallei modulates host iron homeostasis to facilitate iron availability and intracellular survival.

Schmidt IHE, Gildhorn C, Böning MAL, Kulow VA, Steinmetz I, Bast A.

PLoS Negl Trop Dis. 2018 Jan 12;12(1):e0006096. doi: 10.1371/journal.pntd.0006096. eCollection 2018 Jan.

8.

A simple laboratory algorithm for diagnosis of melioidosis in resource-constrained areas: a study from north-central Vietnam.

Trinh TT, Hoang TS, Tran DA, Trinh VT, Göhler A, Nguyen TT, Hoang SN, Krumkamp R, Nguyen LTN, May J, Doan PM, Do CD, Que TA, Steinmetz I.

Clin Microbiol Infect. 2018 Jan;24(1):84.e1-84.e4. doi: 10.1016/j.cmi.2017.07.029. Epub 2017 Aug 3.

9.

Entry, Intracellular Survival, and Multinucleated-Giant-Cell-Forming Activity of Burkholderia pseudomallei in Human Primary Phagocytic and Nonphagocytic Cells.

Whiteley L, Meffert T, Haug M, Weidenmaier C, Hopf V, Bitschar K, Schittek B, Kohler C, Steinmetz I, West TE, Schwarz S.

Infect Immun. 2017 Sep 20;85(10). pii: e00468-17. doi: 10.1128/IAI.00468-17. Print 2017 Oct.

10.

Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster.

Borlee GI, Plumley BA, Martin KH, Somprasong N, Mangalea MR, Islam MN, Burtnick MN, Brett PJ, Steinmetz I, AuCoin DP, Belisle JT, Crick DC, Schweizer HP, Borlee BR.

PLoS Negl Trop Dis. 2017 Jun 28;11(6):e0005689. doi: 10.1371/journal.pntd.0005689. eCollection 2017 Jun.

11.

Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae from Pharmaceutical Wastewaters in South-Western Nigeria.

Obasi A, Nwachukwu S, Ugoji E, Kohler C, Göhler A, Balau V, Pfeifer Y, Steinmetz I.

Microb Drug Resist. 2017 Dec;23(8):1013-1018. doi: 10.1089/mdr.2016.0269. Epub 2017 Apr 4.

PMID:
28375698
12.

Multitarget Quantitative PCR Improves Detection and Predicts Cultivability of the Pathogen Burkholderia pseudomallei.

Göhler A, Trung TT, Hopf V, Kohler C, Hartleib J, Wuthiekanun V, Peacock SJ, Limmathurotsakul D, Tuanyok A, Steinmetz I.

Appl Environ Microbiol. 2017 Mar 31;83(8). pii: e03212-16. doi: 10.1128/AEM.03212-16. Print 2017 Apr 15.

13.

NADPH Oxidase Contributes to Resistance against Aggregatibacter actinomycetemcomitans-Induced Periodontitis in Mice.

Bast A, Kubis H, Holtfreter B, Ribback S, Martin H, Schreiner HC, Dominik MJ, Breitbach K, Dombrowski F, Kocher T, Steinmetz I.

Infect Immun. 2017 Jan 26;85(2). pii: e00849-16. doi: 10.1128/IAI.00849-16. Print 2017 Feb.

14.

Monitoring of abdominal Staphylococcus aureus infection using magnetic resonance imaging: a murine animal model for hepatic and renal abscesses.

Kromrey ML, Göhler A, Friedrich N, Kindermann K, Hadlich S, Puls D, Steinmetz I, Kühn JP.

Eur J Clin Microbiol Infect Dis. 2017 Feb;36(2):373-378. doi: 10.1007/s10096-016-2811-9. Epub 2016 Oct 24.

PMID:
27778120
15.

Molecular Epidemiology of Staphylococcus aureus in the General Population in Northeast Germany: Results of the Study of Health in Pomerania (SHIP-TREND-0).

Holtfreter S, Grumann D, Balau V, Barwich A, Kolata J, Goehler A, Weiss S, Holtfreter B, Bauerfeind SS, Döring P, Friebe E, Haasler N, Henselin K, Kühn K, Nowotny S, Radke D, Schulz K, Schulz SR, Trübe P, Vu CH, Walther B, Westphal S, Cuny C, Witte W, Völzke H, Grabe HJ, Kocher T, Steinmetz I, Bröker BM.

J Clin Microbiol. 2016 Nov;54(11):2774-2785. Epub 2016 Sep 7.

16.

Sepsis Caused by Extended-Spectrum Beta-Lactamase (ESBL)-Positive K. pneumoniae and E. coli: Comparison of Severity of Sepsis, Delay of Anti-Infective Therapy and ESBL Genotype.

Sakellariou C, Gürntke S, Steinmetz I, Kohler C, Pfeifer Y, Gastmeier P, Schwab F, Kola A, Deja M, Leistner R.

PLoS One. 2016 Jul 21;11(7):e0158039. doi: 10.1371/journal.pone.0158039. eCollection 2016.

17.

Rapid and Sensitive Multiplex Detection of Burkholderia pseudomallei-Specific Antibodies in Melioidosis Patients Based on a Protein Microarray Approach.

Kohler C, Dunachie SJ, Müller E, Kohler A, Jenjaroen K, Teparrukkul P, Baier V, Ehricht R, Steinmetz I.

PLoS Negl Trop Dis. 2016 Jul 18;10(7):e0004847. doi: 10.1371/journal.pntd.0004847. eCollection 2016 Jul.

18.

Heme Oxygenase-1 and Carbon Monoxide Promote Burkholderia pseudomallei Infection.

Stolt C, Schmidt IH, Sayfart Y, Steinmetz I, Bast A.

J Immunol. 2016 Aug 1;197(3):834-46. doi: 10.4049/jimmunol.1403104. Epub 2016 Jun 17.

19.

Burkholderia pseudomallei Colony Morphotypes Show a Synchronized Metabolic Pattern after Acute Infection.

Gierok P, Kohler C, Steinmetz I, Lalk M.

PLoS Negl Trop Dis. 2016 Mar 4;10(3):e0004483. doi: 10.1371/journal.pntd.0004483. eCollection 2016 Mar.

20.

Structural analysis and knock-out of a Burkholderia pseudomallei homolog of the eukaryotic transcription coactivator PC4.

Werten S, Kohler C, Bayer NJ, Steinmetz I, Hinrichs W.

Gene. 2016 Feb 15;577(2):140-7. doi: 10.1016/j.gene.2015.11.037. Epub 2015 Nov 25.

PMID:
26625975
21.

Melioidosis diagnostic workshop, 2013.

Hoffmaster AR, AuCoin D, Baccam P, Baggett HC, Baird R, Bhengsri S, Blaney DD, Brett PJ, Brooks TJ, Brown KA, Chantratita N, Cheng AC, Dance DA, Decuypere S, Defenbaugh D, Gee JE, Houghton R, Jorakate P, Lertmemongkolchai G, Limmathurotsakul D, Merlin TL, Mukhopadhyay C, Norton R, Peacock SJ, Rolim DB, Simpson AJ, Steinmetz I, Stoddard RA, Stokes MM, Sue D, Tuanyok A, Whistler T, Wuthiekanun V, Walke HT.

Emerg Infect Dis. 2015 Feb;21(2). doi: 10.3201/eid2102.141045.

22.

Molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-positive Klebsiella pneumoniae from bloodstream infections and risk factors for mortality.

Gürntke S, Kohler C, Steinmetz I, Pfeifer Y, Eller C, Gastmeier P, Schwab F, Leistner R.

J Infect Chemother. 2014 Dec;20(12):817-9. doi: 10.1016/j.jiac.2014.08.012. Epub 2014 Sep 13.

PMID:
25224765
23.

Quantitative molecular detection of putative periodontal pathogens in clinically healthy and periodontally diseased subjects.

Göhler A, Hetzer A, Holtfreter B, Geisel MH, Schmidt CO, Steinmetz I, Kocher T.

PLoS One. 2014 Jul 16;9(7):e99244. doi: 10.1371/journal.pone.0099244. eCollection 2014.

24.

[Surveillance reports on pathogens and their antibiotic resistance patterns - a recommendation for standardization].

Warnke P, Aepfelbacher M, Fickenscher H, Solbach W, Steinmetz I, Podbielski A.

Dtsch Med Wochenschr. 2014 Jun;139(25-26):1377-82. doi: 10.1055/s-0034-1370124. Epub 2014 Jun 10. Review. German.

PMID:
24914516
25.

Bone marrow-derived macrophages from BALB/c and C57BL/6 mice fundamentally differ in their respiratory chain complex proteins, lysosomal enzymes and components of antioxidant stress systems.

Depke M, Breitbach K, Dinh Hoang Dang K, Brinkmann L, Salazar MG, Dhople VM, Bast A, Steil L, Schmidt F, Steinmetz I, Völker U.

J Proteomics. 2014 May 30;103:72-86. doi: 10.1016/j.jprot.2014.03.027. Epub 2014 Apr 1.

PMID:
24704164
26.

Mortality and molecular epidemiology associated with extended-spectrum β-lactamase production in Escherichia coli from bloodstream infection.

Leistner R, Sakellariou C, Gürntke S, Kola A, Steinmetz I, Kohler C, Pfeifer Y, Eller C, Gastmeier P, Schwab F.

Infect Drug Resist. 2014 Mar 13;7:57-62. doi: 10.2147/IDR.S56984. eCollection 2014.

27.

Caspase-1-dependent and -independent cell death pathways in Burkholderia pseudomallei infection of macrophages.

Bast A, Krause K, Schmidt IH, Pudla M, Brakopp S, Hopf V, Breitbach K, Steinmetz I.

PLoS Pathog. 2014 Mar 13;10(3):e1003986. doi: 10.1371/journal.ppat.1003986. eCollection 2014 Mar.

28.

BPSS1504, a cluster 1 type VI secretion gene, is involved in intracellular survival and virulence of Burkholderia pseudomallei.

Hopf V, Göhler A, Eske-Pogodda K, Bast A, Steinmetz I, Breitbach K.

Infect Immun. 2014 May;82(5):2006-15. doi: 10.1128/IAI.01544-14. Epub 2014 Mar 4.

29.

Glyburide reduces bacterial dissemination in a mouse model of melioidosis.

Koh GC, Weehuizen TA, Breitbach K, Krause K, de Jong HK, Kager LM, Hoogendijk AJ, Bast A, Peacock SJ, van der Poll T, Steinmetz I, Wiersinga WJ.

PLoS Negl Trop Dis. 2013 Oct 17;7(10):e2500. doi: 10.1371/journal.pntd.0002500. eCollection 2013.

30.

Identification of genetic loci associated with Helicobacter pylori serologic status.

Mayerle J, den Hoed CM, Schurmann C, Stolk L, Homuth G, Peters MJ, Capelle LG, Zimmermann K, Rivadeneira F, Gruska S, Völzke H, de Vries AC, Völker U, Teumer A, van Meurs JB, Steinmetz I, Nauck M, Ernst F, Weiss FU, Hofman A, Zenker M, Kroemer HK, Prokisch H, Uitterlinden AG, Lerch MM, Kuipers EJ.

JAMA. 2013 May 8;309(18):1912-20. doi: 10.1001/jama.2013.4350. Erratum in: JAMA. 2013 Jul 3;310(1):99. Kuipers, Ernst [corrected to Kuipers, Ernst J].

PMID:
23652523
31.

Systematic review and consensus guidelines for environmental sampling of Burkholderia pseudomallei.

Limmathurotsakul D, Dance DA, Wuthiekanun V, Kaestli M, Mayo M, Warner J, Wagner DM, Tuanyok A, Wertheim H, Yoke Cheng T, Mukhopadhyay C, Puthucheary S, Day NP, Steinmetz I, Currie BJ, Peacock SJ.

PLoS Negl Trop Dis. 2013;7(3):e2105. doi: 10.1371/journal.pntd.0002105. Epub 2013 Mar 21. Review.

32.

Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei Infection, 2010.

Lipsitz R, Garges S, Aurigemma R, Baccam P, Blaney DD, Cheng AC, Currie BJ, Dance D, Gee JE, Larsen J, Limmathurotsakul D, Morrow MG, Norton R, O'Mara E, Peacock SJ, Pesik N, Rogers LP, Schweizer HP, Steinmetz I, Tan G, Tan P, Wiersinga WJ, Wuthiekanun V, Smith TL.

Emerg Infect Dis. 2012 Dec;18(12):e2. doi: 10.3201/eid1812.120638.

33.

High prevalence of extended-spectrum-β-lactamase-producing Enterobacteriaceae in organic and conventional retail chicken meat, Germany.

Kola A, Kohler C, Pfeifer Y, Schwab F, Kühn K, Schulz K, Balau V, Breitbach K, Bast A, Witte W, Gastmeier P, Steinmetz I.

J Antimicrob Chemother. 2012 Nov;67(11):2631-4. doi: 10.1093/jac/dks295. Epub 2012 Aug 6.

PMID:
22868643
34.

Recent progress in melioidosis and glanders.

Torres AG, Steinmetz I.

Front Microbiol. 2012 Apr 19;3:149. doi: 10.3389/fmicb.2012.00149. eCollection 2012. No abstract available.

35.

Defense Mechanisms of Hepatocytes Against Burkholderia pseudomallei.

Bast A, Schmidt IH, Brauner P, Brix B, Breitbach K, Steinmetz I.

Front Microbiol. 2012 Jan 10;2:277. doi: 10.3389/fmicb.2011.00277. eCollection 2011.

36.

Toxoplasmosis after allogeneic stem cell transplantation--a single centre experience.

Busemann C, Ribback S, Zimmermann K, Sailer V, Kiefer T, Schmidt CA, Schulz K, Steinmetz I, Dombrowski F, Dölken G, Krüger WH.

Ann Hematol. 2012 Jul;91(7):1081-9. doi: 10.1007/s00277-012-1406-5. Epub 2012 Jan 17.

PMID:
22249208
37.

Highly sensitive direct detection and quantification of Burkholderia pseudomallei bacteria in environmental soil samples by using real-time PCR.

Trung TT, Hetzer A, Göhler A, Topfstedt E, Wuthiekanun V, Limmathurotsakul D, Peacock SJ, Steinmetz I.

Appl Environ Microbiol. 2011 Sep;77(18):6486-94. doi: 10.1128/AEM.00735-11. Epub 2011 Jul 29.

38.

A novel FK-506-binding-like protein that lacks peptidyl-prolyl isomerase activity is involved in intracellular infection and in vivo virulence of Burkholderia pseudomallei.

Norville IH, Breitbach K, Eske-Pogodda K, Harmer NJ, Sarkar-Tyson M, Titball RW, Steinmetz I.

Microbiology. 2011 Sep;157(Pt 9):2629-38. doi: 10.1099/mic.0.049163-0. Epub 2011 Jun 16.

PMID:
21680634
39.

PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2.

Erttmann SF, Bast A, Seidel J, Breitbach K, Walther R, Steinmetz I.

Free Radic Biol Med. 2011 Aug 1;51(3):626-40. doi: 10.1016/j.freeradbiomed.2011.05.022. Epub 2011 May 27.

PMID:
21651978
40.

Transmission of cytomegalovirus (CMV) infection by leukoreduced blood products not tested for CMV antibodies: a single-center prospective study in high-risk patients undergoing allogeneic hematopoietic stem cell transplantation (CME).

Thiele T, Krüger W, Zimmermann K, Ittermann T, Wessel A, Steinmetz I, Dölken G, Greinacher A.

Transfusion. 2011 Dec;51(12):2620-6. doi: 10.1111/j.1537-2995.2011.03203.x. Epub 2011 Jun 3.

PMID:
21645009
41.

NADPH-oxidase but not inducible nitric oxide synthase contributes to resistance in a murine Staphylococcus aureus Newman pneumonia model.

Köhler J, Breitbach K, Renner C, Heitsch AK, Bast A, van Rooijen N, Vogelgesang S, Steinmetz I.

Microbes Infect. 2011 Oct;13(11):914-22. doi: 10.1016/j.micinf.2011.05.004. Epub 2011 May 27.

PMID:
21635963
42.

Improved culture-based detection and quantification of Burkholderia pseudomallei from soil.

Trung TT, Hetzer A, Topfstedt E, Göhler A, Limmathurotsakul D, Wuthiekanun V, Peacock SJ, Steinmetz I.

Trans R Soc Trop Med Hyg. 2011 Jun;105(6):346-51. doi: 10.1016/j.trstmh.2011.03.004. Epub 2011 May 4.

PMID:
21543099
43.

Distinct roles for nitric oxide in resistant C57BL/6 and susceptible BALB/c mice to control Burkholderia pseudomallei infection.

Breitbach K, Wongprompitak P, Steinmetz I.

BMC Immunol. 2011 Mar 16;12:20. doi: 10.1186/1471-2172-12-20.

44.

Aminoglycoside-free interventional antibiotic management in patients undergoing haemopoietic stem cell transplantation.

Krüger WH, Kiefer T, Daeschlein G, Steinmetz I, Kramer A, Dölken G.

GMS Krankenhhyg Interdiszip. 2010 Sep 21;5(2). pii: Doc06. doi: 10.3205/dgkh000149.

45.

Influence of iNOS and COX on peroxiredoxin gene expression in primary macrophages.

Bast A, Erttmann SF, Walther R, Steinmetz I.

Free Radic Biol Med. 2010 Dec 15;49(12):1881-91. doi: 10.1016/j.freeradbiomed.2010.09.015. Epub 2010 Oct 8.

PMID:
20869433
46.

Caspase-1 mediates resistance in murine melioidosis.

Breitbach K, Sun GW, Köhler J, Eske K, Wongprompitak P, Tan G, Liu Y, Gan YH, Steinmetz I.

Infect Immun. 2009 Apr;77(4):1589-95. doi: 10.1128/IAI.01257-08. Epub 2009 Jan 29.

47.

Induction of protective immunity against Burkholderia pseudomallei using attenuated mutants with defects in the intracellular life cycle.

Breitbach K, Köhler J, Steinmetz I.

Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S89-94. doi: 10.1016/S0035-9203(08)70022-1.

PMID:
19121696
48.

Clinical and microbiological features of melioidosis in northern Vietnam.

Phuong DM, Trung TT, Breitbach K, Tuan NQ, Nübel U, Flunker G, Khang DD, Quang NX, Steinmetz I.

Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S30-6. doi: 10.1016/S0035-9203(08)70009-9.

PMID:
19121682
49.

Generation of murine bone marrow derived macrophages in a standardised serum-free cell culture system.

Eske K, Breitbach K, Köhler J, Wongprompitak P, Steinmetz I.

J Immunol Methods. 2009 Mar 15;342(1-2):13-9. doi: 10.1016/j.jim.2008.11.011. Epub 2009 Jan 6.

PMID:
19133267
50.

Detrimental role of CC chemokine receptor 4 in murine polymicrobial sepsis.

Traeger T, Kessler W, Assfalg V, Cziupka K, Koerner P, Dassow C, Breitbach K, Mikulcak M, Steinmetz I, Pfeffer K, Heidecke CD, Maier S.

Infect Immun. 2008 Nov;76(11):5285-93. doi: 10.1128/IAI.00310-08. Epub 2008 Sep 2.

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