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Items: 1 to 50 of 687

1.

Anti-CTLA-4 synergizes with dendritic cell-targeted vaccine to promote IL-3-dependent CD4+ effector T cell infiltration into murine pancreatic tumors.

Zaidi N, Quezada SA, Kuroiwa JMY, Zhang L, Jaffee EM, Steinman RM, Wang B.

Ann N Y Acad Sci. 2019 Jun;1445(1):62-73. doi: 10.1111/nyas.14049. Epub 2019 Apr 4.

PMID:
30945313
2.

Implantable cardioverter-defibrillators in heart failure patients with reduced ejection fraction and diabetes.

Sharma A, Al-Khatib SM, Ezekowitz JA, Cooper LB, Fordyce CB, Michael Felker G, Bardy GH, Poole JE, Thomas Bigger J, Buxton AE, Moss AJ, Friedman DJ, Lee KL, Steinman R, Dorian P, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Peterson ED, Inoue LYT, Sanders GD.

Eur J Heart Fail. 2018 Jun;20(6):1031-1038. doi: 10.1002/ejhf.1192. Epub 2018 May 15.

3.

Gestational Diabetes Mellitus: Post-partum Risk and Follow Up.

Poola-Kella S, Steinman RA, Mesmar B, Malek R.

Rev Recent Clin Trials. 2018 Jan 31;13(1):5-14. doi: 10.2174/1574887112666170911124806. Review.

PMID:
28901851
4.

New York Heart Association class and the survival benefit from primary prevention implantable cardioverter defibrillators: A pooled analysis of 4 randomized controlled trials.

Friedman DJ, Al-Khatib SM, Zeitler EP, Han J, Bardy GH, Poole JE, Bigger JT, Buxton AE, Moss AJ, Lee KL, Steinman R, Dorian P, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Inoue LYT, Sanders GD.

Am Heart J. 2017 Sep;191:21-29. doi: 10.1016/j.ahj.2017.06.002. Epub 2017 Jun 9. Review.

5.

Pillars Article: Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. 1998. 282: 480-483.

Randolph GJ, Beaulieu S, Lebecque S, Steinman RM, Muller WA.

J Immunol. 2017 Jun 1;198(11):4191-4194. No abstract available.

6.

In vivo targeting of protein antigens to dendritic cells using anti-DEC-205 single chain antibody improves HIV Gag specific CD4+ T cell responses protecting from airway challenge with recombinant vaccinia-gag virus.

Ngu LN, Nji NN, Ambada GE, Sagnia B, Sake CN, Tchadji JC, Njambe Priso GD, Lissom A, Tchouangueu TF, Manga Tebit D, Waffo AB, Park CG, Steinman RM, Überla K, Nchinda GW.

Immun Inflamm Dis. 2019 Jun;7(2):55-67. doi: 10.1002/iid3.151. Epub 2017 Mar 13.

7.

Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals.

Huang J, Woods P, Normolle D, Goff JP, Benos PV, Stehle CJ, Steinman RA.

Breast Cancer Res Treat. 2017 Jan;161(2):229-243. doi: 10.1007/s10549-016-4052-0. Epub 2016 Nov 16.

8.

Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses.

Sela U, Park CG, Park A, Olds P, Wang S, Steinman RM, Fischetti VA.

PLoS One. 2016 Jan 8;11(1):e0146412. doi: 10.1371/journal.pone.0146412. eCollection 2016.

9.

ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis.

Silva-Sánchez A, Meza-Pérez S, Flores-Langarica A, Donis-Maturano L, Estrada-García I, Calderón-Amador J, Hernández-Pando R, Idoyaga J, Steinman RM, Flores-Romo L.

PLoS One. 2015 Apr 27;10(4):e0124828. doi: 10.1371/journal.pone.0124828. eCollection 2015.

10.

Survival benefit of the primary prevention implantable cardioverter-defibrillator among older patients: does age matter? An analysis of pooled data from 5 clinical trials.

Hess PL, Al-Khatib SM, Han JY, Edwards R, Bardy GH, Bigger JT, Buxton A, Cappato R, Dorian P, Hallstrom A, Kadish AH, Kudenchuk PJ, Lee KL, Mark DB, Moss AJ, Steinman R, Inoue LY, Sanders G.

Circ Cardiovasc Qual Outcomes. 2015 Mar;8(2):179-86. doi: 10.1161/CIRCOUTCOMES.114.001306. Epub 2015 Feb 10.

11.

Outcomes of implantable cardioverter-defibrillator use in patients with comorbidities: results from a combined analysis of 4 randomized clinical trials.

Steinberg BA, Al-Khatib SM, Edwards R, Han J, Bardy GH, Bigger JT, Buxton AE, Moss AJ, Lee KL, Steinman R, Dorian P, Hallstrom A, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Inoue LY, Sanders GD.

JACC Heart Fail. 2014 Dec;2(6):623-9. doi: 10.1016/j.jchf.2014.06.007. Epub 2014 Oct 8.

12.

Classical Flt3L-dependent dendritic cells control immunity to protein vaccine.

Anandasabapathy N, Feder R, Mollah S, Tse SW, Longhi MP, Mehandru S, Matos I, Cheong C, Ruane D, Brane L, Teixeira A, Dobrin J, Mizenina O, Park CG, Meredith M, Clausen BE, Nussenzweig MC, Steinman RM.

J Exp Med. 2014 Aug 25;211(9):1875-91. doi: 10.1084/jem.20131397. Epub 2014 Aug 18.

13.

Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.

Flacher V, Tripp CH, Mairhofer DG, Steinman RM, Stoitzner P, Idoyaga J, Romani N.

EMBO Mol Med. 2014 Sep;6(9):1191-204. doi: 10.15252/emmm.201303283. Erratum in: EMBO Mol Med. 2014 Dec;6(12):1638.

14.

Implantable cardioverter-defibrillators for primary prevention of sudden cardiac death in CKD: a meta-analysis of patient-level data from 3 randomized trials.

Pun PH, Al-Khatib SM, Han JY, Edwards R, Bardy GH, Bigger JT, Buxton AE, Moss AJ, Lee KL, Steinman R, Dorian P, Hallstrom A, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Hess PL, Inoue LY, Sanders GD.

Am J Kidney Dis. 2014 Jul;64(1):32-9. doi: 10.1053/j.ajkd.2013.12.009. Epub 2014 Feb 8.

15.

Do patients with a left ventricular ejection fraction between 30% and 35% benefit from a primary prevention implantable cardioverter defibrillator?

Al-Khatib SM, Han JY, Edwards R, Bardy GH, Bigger JT, Buxton AE, Cappato R, Dorian P, Hallstrom A, Kadish AH, Kudenchuk PJ, Lee KL, Mark DB, Moss AJ, Steinman R, Inoue LY, Sanders GD.

Int J Cardiol. 2014 Mar 1;172(1):253-4. doi: 10.1016/j.ijcard.2013.12.278. Epub 2014 Jan 10. No abstract available.

PMID:
24467982
16.

Direct type I IFN but not MDA5/TLR3 activation of dendritic cells is required for maturation and metabolic shift to glycolysis after poly IC stimulation.

Pantel A, Teixeira A, Haddad E, Wood EG, Steinman RM, Longhi MP.

PLoS Biol. 2014 Jan;12(1):e1001759. doi: 10.1371/journal.pbio.1001759. Epub 2014 Jan 7.

17.

Temporal analysis of the usage log of a research networking system.

Yoon S, Trembowelski S, Steinman RC, Bakken S, Weng C.

AMIA Jt Summits Transl Sci Proc. 2014 Apr 7;2014:116-22. eCollection 2014.

18.

Using software to elicit user needs for clinical research visit scheduling.

Weng C, Boland MR, So Y, Rusanov A, Lopez C, Steinman R, Busacca L, Bakken S, Bigger JT.

AMIA Jt Summits Transl Sci Proc. 2014 Apr 7;2014:109-15. eCollection 2014.

19.

From expert-derived user needs to user-perceived ease of use and usefulness: a two-phase mixed-methods evaluation framework.

Boland MR, Rusanov A, So Y, Lopez-Jimenez C, Busacca L, Steinman RC, Bakken S, Bigger JT, Weng C.

J Biomed Inform. 2014 Dec;52:141-50. doi: 10.1016/j.jbi.2013.12.004. Epub 2013 Dec 12.

20.

Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells.

Mollah SA, Dobrin JS, Feder RE, Tse SW, Matos IG, Cheong C, Steinman RM, Anandasabapathy N.

J Invest Dermatol. 2014 May;134(5):1265-1275. doi: 10.1038/jid.2013.515. Epub 2013 Nov 28. Erratum in: J Invest Dermatol. 2014 Nov;134(11):2850-1.

21.

A combined anatomic and electrophysiologic substrate based approach for sudden cardiac death risk stratification.

Merchant FM, Zheng H, Bigger T, Steinman R, Ikeda T, Pedretti RF, Salerno-Uriarte JA, Klersy C, Chan PS, Bartone C, Hohnloser SH, Ruskin JN, Armoundas AA.

Am Heart J. 2013 Oct;166(4):744-52. doi: 10.1016/j.ahj.2013.06.023. Epub 2013 Sep 18. Review.

22.

Lung dendritic cells induce migration of protective T cells to the gastrointestinal tract.

Ruane D, Brane L, Reis BS, Cheong C, Poles J, Do Y, Zhu H, Velinzon K, Choi JH, Studt N, Mayer L, Lavelle EC, Steinman RM, Mucida D, Mehandru S.

J Exp Med. 2013 Aug 26;210(9):1871-88. doi: 10.1084/jem.20122762. Epub 2013 Aug 19.

23.

Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity.

Matos I, Mizenina O, Lubkin A, Steinman RM, Idoyaga J.

PLoS One. 2013 Jun 26;8(6):e67453. doi: 10.1371/journal.pone.0067453. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/5149bf8e-3843-4865-a726-0ca2820ee8f8.

24.

An Integrated Model for Patient Care and Clinical Trials (IMPACT) to support clinical research visit scheduling workflow for future learning health systems.

Weng C, Li Y, Berhe S, Boland MR, Gao J, Hruby GW, Steinman RC, Lopez-Jimenez C, Busacca L, Hripcsak G, Bakken S, Bigger JT.

J Biomed Inform. 2013 Aug;46(4):642-52. doi: 10.1016/j.jbi.2013.05.001. Epub 2013 May 16.

25.

Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice.

Coconi-Linares N, Ortega-Dávila E, López-González M, García-Machorro J, García-Cordero J, Steinman RM, Cedillo-Barrón L, Gómez-Lim MA.

Vaccine. 2013 May 1;31(19):2366-71. doi: 10.1016/j.vaccine.2013.03.009. Epub 2013 Mar 15.

PMID:
23499580
26.

CD141+ dendritic cells produce prominent amounts of IFN-α after dsRNA recognition and can be targeted via DEC-205 in humanized mice.

Meixlsperger S, Leung CS, Rämer PC, Pack M, Vanoaica LD, Breton G, Pascolo S, Salazar AM, Dzionek A, Schmitz J, Steinman RM, Münz C.

Blood. 2013 Jun 20;121(25):5034-44. doi: 10.1182/blood-2012-12-473413. Epub 2013 Mar 12.

27.

Survival benefit of primary prevention implantable cardioverter-defibrillator therapy after myocardial infarction: does time to implant matter? A meta-analysis using patient-level data from 4 clinical trials.

Hess PL, Laird A, Edwards R, Bardy GH, Bigger JT, Buxton AE, Moss AJ, Lee KL, Hall WJ, Steinman R, Dorian P, Hallstrom A, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Al-Khatib SM, Piccini JP, Inoue LY, Sanders GD.

Heart Rhythm. 2013 Jun;10(6):828-35. doi: 10.1016/j.hrthm.2013.02.011. Epub 2013 Feb 13.

28.

Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells.

Barbuto S, Idoyaga J, Vila-Perelló M, Longhi MP, Breton G, Steinman RM, Muir TW.

Nat Chem Biol. 2013 Apr;9(4):250-6. doi: 10.1038/nchembio.1186. Epub 2013 Feb 17.

29.

Two cases of malignant struma ovarii with metastasis to pelvic bone.

Steinman RA, De Castro IO, Shrayyef M, Chengazi V, Giampoli E, Van Der Sloot P, Calvi LM, Wittlin SD, Hammes SR, Hou R.

Gynecol Obstet Invest. 2013;75(2):139-44. doi: 10.1159/000345863. Epub 2013 Feb 6.

PMID:
23391779
30.

Specialized role of migratory dendritic cells in peripheral tolerance induction.

Idoyaga J, Fiorese C, Zbytnuik L, Lubkin A, Miller J, Malissen B, Mucida D, Merad M, Steinman RM.

J Clin Invest. 2013 Feb;123(2):844-54. doi: 10.1172/JCI65260. Epub 2013 Jan 9.

31.

Antifibrotic effects of roscovitine in normal and scleroderma fibroblasts.

Steinman RA, Robinson AR, Feghali-Bostwick CA.

PLoS One. 2012;7(11):e48560. doi: 10.1371/journal.pone.0048560. Epub 2012 Nov 20.

32.

Effect of left ventricular ejection fraction and QRS duration on the survival benefit of implantable cardioverter-defibrillators: meta-analysis of primary prevention trials.

Katritsis DG, Siontis KC, Bigger JT, Kadish AH, Steinman R, Zareba W, Siontis GC, Bardy GH, Ioannidis JP.

Heart Rhythm. 2013 Feb;10(2):200-6. doi: 10.1016/j.hrthm.2012.10.039. Epub 2012 Oct 27. Review.

PMID:
23107652
33.

Zoledronic acid effectiveness against breast cancer metastases - a role for estrogen in the microenvironment?

Steinman RA, Brufsky AM, Oesterreich S.

Breast Cancer Res. 2012 Sep 21;14(5):213. doi: 10.1186/bcr3223. Review.

34.

Deletion of the RNA-editing enzyme ADAR1 causes regression of established chronic myelogenous leukemia in mice.

Steinman RA, Yang Q, Gasparetto M, Robinson LJ, Liu X, Lenzner DE, Hou J, Smith C, Wang Q.

Int J Cancer. 2013 Apr 15;132(8):1741-50. doi: 10.1002/ijc.27851. Epub 2012 Oct 17.

35.

Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor.

Do Y, Didierlaurent AM, Ryu S, Koh H, Park CG, Park S, Perlin DS, Powell BS, Steinman RM.

Vaccine. 2012 Oct 5;30(45):6359-67. doi: 10.1016/j.vaccine.2012.08.051. Epub 2012 Sep 1.

36.

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

Bozzacco L, Yu H, Dengjel J, Trumpfheller C, Zebroski HA 3rd, Zhang N, Küttner V, Ueberheide BM, Deng H, Chait BT, Steinman RM, Mojsov S, Fenyö D.

PLoS One. 2012;7(7):e41897. doi: 10.1371/journal.pone.0041897. Epub 2012 Jul 30.

37.

PE-Cy5.5 conjugates bind to the cells expressing mouse DEC205/CD205.

Park CG, Rodriguez A, Steinman RM.

J Immunol Methods. 2012 Oct 31;384(1-2):184-90. doi: 10.1016/j.jim.2012.07.011. Epub 2012 Jul 25.

38.

Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.

Billiard F, Lobry C, Darrasse-Jèze G, Waite J, Liu X, Mouquet H, DaNave A, Tait M, Idoyaga J, Leboeuf M, Kyratsous CA, Burton J, Kalter J, Klinakis A, Zhang W, Thurston G, Merad M, Steinman RM, Murphy AJ, Yancopoulos GD, Aifantis I, Skokos D.

J Exp Med. 2012 May 7;209(5):1011-28. doi: 10.1084/jem.20111615. Epub 2012 Apr 30.

39.
40.

Generation of anti-human DEC205/CD205 monoclonal antibodies that recognize epitopes conserved in different mammals.

Park CG, Rodriguez A, Ueta H, Lee H, Pack M, Matsuno K, Steinman RM.

J Immunol Methods. 2012 Mar 30;377(1-2):15-22. doi: 10.1016/j.jim.2011.12.009. Epub 2012 Jan 16.

41.

Treml4, an Ig superfamily member, mediates presentation of several antigens to T cells in vivo, including protective immunity to HER2 protein.

Hemmi H, Zaidi N, Wang B, Matos I, Fiorese C, Lubkin A, Zbytnuik L, Suda K, Zhang K, Noda M, Kaisho T, Steinman RM, Idoyaga J.

J Immunol. 2012 Feb 1;188(3):1147-55. doi: 10.4049/jimmunol.1102541. Epub 2011 Dec 30.

42.

Decisions about dendritic cells: past, present, and future.

Steinman RM.

Annu Rev Immunol. 2012;30:1-22. doi: 10.1146/annurev-immunol-100311-102839. Epub 2011 Nov 17. Review.

PMID:
22136168
43.

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity.

Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ, Steinman RM.

J Intern Med. 2012 Feb;271(2):183-92. doi: 10.1111/j.1365-2796.2011.02496.x. Epub 2012 Jan 4. Review.

44.

Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice.

Sela U, Olds P, Park A, Schlesinger SJ, Steinman RM.

J Exp Med. 2011 Nov 21;208(12):2489-96. doi: 10.1084/jem.20110466. Epub 2011 Nov 14.

45.

Flt3 signaling-dependent dendritic cells protect against atherosclerosis.

Choi JH, Cheong C, Dandamudi DB, Park CG, Rodriguez A, Mehandru S, Velinzon K, Jung IH, Yoo JY, Oh GT, Steinman RM.

Immunity. 2011 Nov 23;35(5):819-31. doi: 10.1016/j.immuni.2011.09.014. Epub 2011 Nov 10.

46.

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans.

Caskey M, Lefebvre F, Filali-Mouhim A, Cameron MJ, Goulet JP, Haddad EK, Breton G, Trumpfheller C, Pollak S, Shimeliovich I, Duque-Alarcon A, Pan L, Nelkenbaum A, Salazar AM, Schlesinger SJ, Steinman RM, Sékaly RP.

J Exp Med. 2011 Nov 21;208(12):2357-66. doi: 10.1084/jem.20111171. Epub 2011 Nov 7.

47.

Cancer therapeutics: time to swim downstream?

Steinman R.

Oncologist. 2011;16(10):1479-80. doi: 10.1634/theoncologist.2011-0241. No abstract available.

48.

A new synthetic TLR4 agonist, GLA, allows dendritic cells targeted with antigen to elicit Th1 T-cell immunity in vivo.

Pantel A, Cheong C, Dandamudi D, Shrestha E, Mehandru S, Brane L, Ruane D, Teixeira A, Bozzacco L, Steinman RM, Longhi MP.

Eur J Immunol. 2012 Jan;42(1):101-9. doi: 10.1002/eji.201141855. Epub 2011 Dec 12.

49.

Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells.

Bozzacco L, Yu H, Zebroski HA, Dengjel J, Deng H, Mojsov S, Steinman RM.

J Proteome Res. 2011 Nov 4;10(11):5016-30. doi: 10.1021/pr200503g. Epub 2011 Oct 14.

50.

SnapShot: Dendritic Cells.

Idoyaga J, Steinman RM.

Cell. 2011 Aug 19;146(4):660-660.e2. doi: 10.1016/j.cell.2011.08.010. No abstract available.

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