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Items: 6

1.

Wnt signaling in development and tissue homeostasis.

Steinhart Z, Angers S.

Development. 2018 Jun 8;145(11). pii: dev146589. doi: 10.1242/dev.146589. Review.

PMID:
29884654
2.

Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S.

Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384d.

PMID:
29117169
3.

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S.

Nat Med. 2017 Jan;23(1):60-68. doi: 10.1038/nm.4219. Epub 2016 Nov 21. Erratum in: Nat Med. 2017 Nov 7;23 (11):1384.

PMID:
27869803
4.

Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay.

Gammons MV, Rutherford TJ, Steinhart Z, Angers S, Bienz M.

J Cell Sci. 2016 Oct 15;129(20):3892-3902.

5.

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins.

Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, Bryja V.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9304-9. doi: 10.1073/pnas.1608783113. Epub 2016 Aug 2.

6.

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

Hart T, Chandrashekhar M, Aregger M, Steinhart Z, Brown KR, MacLeod G, Mis M, Zimmermann M, Fradet-Turcotte A, Sun S, Mero P, Dirks P, Sidhu S, Roth FP, Rissland OS, Durocher D, Angers S, Moffat J.

Cell. 2015 Dec 3;163(6):1515-26. doi: 10.1016/j.cell.2015.11.015. Epub 2015 Nov 25.

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