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Items: 1 to 50 of 377

1.

High-throughput Sequencing of Subcutaneous Panniculitis-like T-Cell Lymphoma Reveals Candidate Pathogenic Mutations.

Fernandez-Pol S, Costa HA, Steiner DF, Ma L, Merker JD, Kim YH, Arber DA, Kim J.

Appl Immunohistochem Mol Morphol. 2019 Nov/Dec;27(10):740-748. doi: 10.1097/PAI.0000000000000683.

PMID:
31702703
2.

Impact of Deep Learning Assistance on the Histopathologic Review of Lymph Nodes for Metastatic Breast Cancer.

Steiner DF, MacDonald R, Liu Y, Truszkowski P, Hipp JD, Gammage C, Thng F, Peng L, Stumpe MC.

Am J Surg Pathol. 2018 Dec;42(12):1636-1646. doi: 10.1097/PAS.0000000000001151.

3.

Identification of Functionally Relevant microRNAs in the Regulation of Allergic Inflammation.

Fassett MS, Pua HH, Simpson LJ, Steiner DF, Ansel KM.

Methods Mol Biol. 2018;1799:341-351. doi: 10.1007/978-1-4939-7896-0_24.

4.

Coexistence of BRAF V600E and TERT Promoter Mutations in Low-grade Serous Carcinoma of Ovary Recurring as Carcinosarcoma in a Lymph Node: Report of a Case.

Tavallaee M, Steiner DF, Zehnder JL, Folkins AK, Karam AK.

Int J Gynecol Pathol. 2019 Jul;38(4):386-392. doi: 10.1097/PGP.0000000000000507.

PMID:
29620581
5.

Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes.

Greeley SA, Zielinski MC, Poudel A, Ye H, Berry S, Taxy JB, Carmody D, Steiner DF, Philipson LH, Wood JR, Hara M.

J Clin Endocrinol Metab. 2017 Jan 1;102(1):1-5. doi: 10.1210/jc.2016-2826.

6.

MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production.

Pua HH, Steiner DF, Patel S, Gonzalez JR, Ortiz-Carpena JF, Kageyama R, Chiou NT, Gallman A, de Kouchkovsky D, Jeker LT, McManus MT, Erle DJ, Ansel KM.

Immunity. 2016 Apr 19;44(4):821-32. doi: 10.1016/j.immuni.2016.01.003. Epub 2016 Feb 2.

7.

Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships.

Weiss M, Steiner DF, Philipson LH.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-.
2014 Feb 1.

8.

Protective hinge in insulin opens to enable its receptor engagement.

Menting JG, Yang Y, Chan SJ, Phillips NB, Smith BJ, Whittaker J, Wickramasinghe NP, Whittaker LJ, Pandyarajan V, Wan ZL, Yadav SP, Carroll JM, Strokes N, Roberts CT Jr, Ismail-Beigi F, Milewski W, Steiner DF, Chauhan VS, Ward CW, Weiss MA, Lawrence MC.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3395-404. doi: 10.1073/pnas.1412897111. Epub 2014 Aug 4.

9.

Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.

Park SY, Ludwig MZ, Tamarina NA, He BZ, Carl SH, Dickerson DA, Barse L, Arun B, Williams CL, Miles CM, Philipson LH, Steiner DF, Bell GI, Kreitman M.

Genetics. 2014 Feb;196(2):539-55. doi: 10.1534/genetics.113.157602. Epub 2013 Nov 26. Erratum in: Genetics. 2014 Dec;198(4):1773.

10.

Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets.

Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skärstrand H, Balhuizen A, Bennet H, Steiner DF, Törn C, Fex M, Lernmark Å.

J Biol Chem. 2013 Oct 4;288(40):29013-23. doi: 10.1074/jbc.M113.478222. Epub 2013 Aug 9.

11.

How insulin engages its primary binding site on the insulin receptor.

Menting JG, Whittaker J, Margetts MB, Whittaker LJ, Kong GK, Smith BJ, Watson CJ, Záková L, Kletvíková E, Jiráček J, Chan SJ, Steiner DF, Dodson GG, Brzozowski AM, Weiss MA, Ward CW, Lawrence MC.

Nature. 2013 Jan 10;493(7431):241-5. doi: 10.1038/nature11781.

12.

Biosynthesis of proTRH-derived peptides in prohormone convertase 1 and 2 knockout mice.

Cyr NE, Stuart RC, Zhu X, Steiner DF, Nillni EA.

Peptides. 2012 May;35(1):42-8. doi: 10.1016/j.peptides.2012.02.024. Epub 2012 Mar 6.

PMID:
22421509
13.

Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion.

Refaie S, Gagnon S, Gagnon H, Desjardins R, D'Anjou F, D'Orléans-Juste P, Zhu X, Steiner DF, Seidah NG, Lazure C, Salzet M, Day R.

J Biol Chem. 2012 Apr 27;287(18):14703-17. doi: 10.1074/jbc.M111.323220. Epub 2012 Mar 6.

14.

MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.

Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, Ansel KM.

Immunity. 2011 Aug 26;35(2):169-81. doi: 10.1016/j.immuni.2011.07.009. Epub 2011 Aug 4.

15.

On the discovery of precursor processing.

Steiner DF.

Methods Mol Biol. 2011;768:3-11. doi: 10.1007/978-1-61779-204-5_1. Review.

PMID:
21805235
16.

Adventures with insulin in the islets of Langerhans.

Steiner DF.

J Biol Chem. 2011 May 20;286(20):17399-421. doi: 10.1074/jbc.X111.244764. Epub 2011 Mar 28.

17.

GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1).

Stein J, Milewski WM, Hara M, Steiner DF, Dey A.

Islets. 2011 Jan-Feb;3(1):21-34. Epub 2011 Jan 1.

18.

Pim3 negatively regulates glucose-stimulated insulin secretion.

Vlacich G, Nawijn MC, Webb GC, Steiner DF.

Islets. 2010 Sep-Oct;2(5):308-17. Epub 2010 Sep 1.

19.

Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.

Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI.

Rev Endocr Metab Disord. 2010 Sep;11(3):205-15. doi: 10.1007/s11154-010-9151-3. Review. Erratum in: Rev Endocr Metab Disord. 2012 Mar;13(1):79-81.

20.

Distinct requirements of microRNAs in NK cell activation, survival, and function.

Bezman NA, Cedars E, Steiner DF, Blelloch R, Hesslein DG, Lanier LL.

J Immunol. 2010 Oct 1;185(7):3835-46. doi: 10.4049/jimmunol.1000980. Epub 2010 Aug 30.

21.
22.

Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics.

Wardman JH, Zhang X, Gagnon S, Castro LM, Zhu X, Steiner DF, Day R, Fricker LD.

J Neurochem. 2010 Jul;114(1):215-25. doi: 10.1111/j.1471-4159.2010.06760.x. Epub 2010 Apr 19.

23.

Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists.

Smith BJ, Huang K, Kong G, Chan SJ, Nakagawa S, Menting JG, Hu SQ, Whittaker J, Steiner DF, Katsoyannis PG, Ward CW, Weiss MA, Lawrence MC.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6771-6. doi: 10.1073/pnas.1001813107. Epub 2010 Mar 26.

24.

Mutant proinsulin proteins associated with neonatal diabetes are retained in the endoplasmic reticulum and not efficiently secreted.

Park SY, Ye H, Steiner DF, Bell GI.

Biochem Biophys Res Commun. 2010 Jan 15;391(3):1449-54. doi: 10.1016/j.bbrc.2009.12.090. Epub 2009 Dec 23.

25.

Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis.

Zhang X, Pan H, Peng B, Steiner DF, Pintar JE, Fricker LD.

J Neurochem. 2010 Mar;112(5):1168-79. doi: 10.1111/j.1471-4159.2009.06530.x. Epub 2009 Dec 7.

26.

A brief perspective on insulin production.

Steiner DF, Park SY, Støy J, Philipson LH, Bell GI.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:189-96. doi: 10.1111/j.1463-1326.2009.01106.x.

PMID:
19817801
27.

β-Cell research - A decade of rapid growth.

Ahrén B, Accili D, Boitard C, Efendic S, Henquin JC, Seino S, Steiner DF, Cerasi E.

Diabetes Obes Metab. 2009 Nov;11 Suppl 4:iv-ix. doi: 10.1111/j.1463-1326.2009.01143.x. No abstract available.

PMID:
19817782
28.

Identification of genetic loci involved in diabetes using a rat model of depression.

Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE.

Mamm Genome. 2009 Aug;20(8):486-97. doi: 10.1007/s00335-009-9211-8. Epub 2009 Aug 22.

29.

No mantle formation in rodent islets -- the prototype of islet revisited.

Kharouta M, Miller K, Kim A, Wojcik P, Kilimnik G, Dey A, Steiner DF, Hara M.

Diabetes Res Clin Pract. 2009 Sep;85(3):252-7. doi: 10.1016/j.diabres.2009.06.021.

30.

Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains.

Zhan S, Zhao H, J White A, Minami M, Pignataro G, Yang T, Zhu X, Lan J, Xiong Z, Steiner DF, Simon RP, Zhou A.

J Cereb Blood Flow Metab. 2009 Apr;29(4):698-706. doi: 10.1038/jcbfm.2008.161. Epub 2009 Jan 14.

31.

Pancreatic beta-cell mass or beta-cell function? That is the question!

Henquin JC, Cerasi E, Efendic S, Steiner DF, Boitard C.

Diabetes Obes Metab. 2008 Nov;10 Suppl 4:1-4. doi: 10.1111/j.1463-1326.2008.00968.x. No abstract available.

PMID:
18834427
32.

Prohormone convertases 1/3 and 2 together orchestrate the site-specific cleavages of progastrin to release gastrin-34 and gastrin-17.

Rehfeld JF, Zhu X, Norrbom C, Bundgaard JR, Johnsen AH, Nielsen JE, Vikesaa J, Stein J, Dey A, Steiner DF, Friis-Hansen L.

Biochem J. 2008 Oct 1;415(1):35-43. doi: 10.1042/BJ20080881.

PMID:
18554181
33.

Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes.

Molven A, Ringdal M, Nordbø AM, Raeder H, Støy J, Lipkind GM, Steiner DF, Philipson LH, Bergmann I, Aarskog D, Undlien DE, Joner G, Søvik O; Norwegian Childhood Diabetes Study Group, Bell GI, Njølstad PR.

Diabetes. 2008 Apr;57(4):1131-5. doi: 10.2337/db07-1467. Epub 2008 Jan 11.

34.

Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.

Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI; Neonatal Diabetes International Collaborative Group, Hattersley AT, Ellard S.

Diabetes. 2008 Apr;57(4):1034-42. Epub 2007 Dec 27.

35.

The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6.

Rehfeld JF, Bundgaard JR, Hannibal J, Zhu X, Norrbom C, Steiner DF, Friis-Hansen L.

Endocrinology. 2008 Apr;149(4):1600-8. Epub 2007 Dec 20.

36.

Of mighty mice and diabetic men: animal models of islet dysfunction.

Efendic S, Boitard C, Ferrannini E, Henquin JC, Steiner DF, Cerasi E.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:1-4. No abstract available.

PMID:
17919172
37.

The A-chain of insulin contacts the insert domain of the insulin receptor. Photo-cross-linking and mutagenesis of a diabetes-related crevice.

Huang K, Chan SJ, Hua QX, Chu YC, Wang RY, Klaproth B, Jia W, Whittaker J, De Meyts P, Nakagawa SH, Steiner DF, Katsoyannis PG, Weiss MA.

J Biol Chem. 2007 Nov 30;282(48):35337-49. Epub 2007 Sep 20.

38.

Insulin gene mutations as a cause of permanent neonatal diabetes.

Støy J, Edghill EL, Flanagan SE, Ye H, Paz VP, Pluzhnikov A, Below JE, Hayes MG, Cox NJ, Lipkind GM, Lipton RB, Greeley SA, Patch AM, Ellard S, Steiner DF, Hattersley AT, Philipson LH, Bell GI; Neonatal Diabetes International Collaborative Group.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15040-4. Epub 2007 Sep 12.

39.

Nestin expression in pancreatic endocrine and exocrine cells of mice lacking glucagon signaling.

Kedees MH, Guz Y, Vuguin PM, Vargas C, Cui L, Steiner DF, Charron MJ, Teitelman G.

Dev Dyn. 2007 Apr;236(4):1126-33.

40.

Complementation analysis demonstrates that insulin cross-links both alpha subunits in a truncated insulin receptor dimer.

Chan SJ, Nakagawa S, Steiner DF.

J Biol Chem. 2007 May 4;282(18):13754-8. Epub 2007 Mar 5.

41.

On the processing of proghrelin to ghrelin.

Zhu X, Cao Y, Voogd K, Steiner DF.

J Biol Chem. 2006 Dec 15;281(50):38867-70. Epub 2006 Oct 18. Erratum in: J Biol Chem. 2007 Jan 19;282(3):2124. Voodg, Keith [corrected to Voogd, Keith].

42.

The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study.

Pan H, Che FY, Peng B, Steiner DF, Pintar JE, Fricker LD.

J Neurochem. 2006 Sep;98(6):1763-77. Epub 2006 Aug 11.

43.

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.

Marzban L, Rhodes CJ, Steiner DF, Haataja L, Halban PA, Verchere CB.

Diabetes. 2006 Aug;55(8):2192-201.

44.

Pancreatic beta cells lack a low glucose and O2-inducible mitochondrial protein that augments cell survival.

Wang J, Cao Y, Chen Y, Chen Y, Gardner P, Steiner DF.

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10636-41. Epub 2006 Jun 30.

46.
47.

Gene duplication and functional divergence of the zebrafish insulin-like growth factor 1 receptors.

Schlueter PJ, Royer T, Farah MH, Laser B, Chan SJ, Steiner DF, Duan C.

FASEB J. 2006 Jun;20(8):1230-2. Epub 2006 May 16.

PMID:
16705083
48.

Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.

Ugleholdt R, Poulsen ML, Holst PJ, Irminger JC, Orskov C, Pedersen J, Rosenkilde MM, Zhu X, Steiner DF, Holst JJ.

J Biol Chem. 2006 Apr 21;281(16):11050-7. Epub 2006 Feb 13.

49.

Nhp6 is a transcriptional initiation fidelity factor for RNA polymerase III transcription in vitro and in vivo.

Kassavetis GA, Steiner DF.

J Biol Chem. 2006 Mar 17;281(11):7445-51. Epub 2006 Jan 11.

50.

Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132: interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3.

Creemers JW, Pritchard LE, Gyte A, Le Rouzic P, Meulemans S, Wardlaw SL, Zhu X, Steiner DF, Davies N, Armstrong D, Lawrence CB, Luckman SM, Schmitz CA, Davies RA, Brennand JC, White A.

Endocrinology. 2006 Apr;147(4):1621-31. Epub 2005 Dec 29.

PMID:
16384863

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