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Items: 8

1.

Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells.

Carey BW, Markoulaki S, Hanna JH, Faddah DA, Buganim Y, Kim J, Ganz K, Steine EJ, Cassady JP, Creyghton MP, Welstead GG, Gao Q, Jaenisch R.

Cell Stem Cell. 2011 Dec 2;9(6):588-98. doi: 10.1016/j.stem.2011.11.003.

2.

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.

Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18061-6. doi: 10.1073/pnas.1114946108. Epub 2011 Oct 19.

3.

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors.

Kim J, Lengner CJ, Kirak O, Hanna J, Cassady JP, Lodato MA, Wu S, Faddah DA, Steine EJ, Gao Q, Fu D, Dawlaty M, Jaenisch R.

Stem Cells. 2011 Jun;29(6):992-1000. doi: 10.1002/stem.641.

4.

Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer.

Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, Jaenisch R, Linhart HG.

J Clin Invest. 2011 May;121(5):1748-52. doi: 10.1172/JCI43169. Epub 2011 Apr 1.

5.

Histone H3K27ac separates active from poised enhancers and predicts developmental state.

Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21931-6. doi: 10.1073/pnas.1016071107. Epub 2010 Nov 24.

6.

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome.

DeKelver RC, Choi VM, Moehle EA, Paschon DE, Hockemeyer D, Meijsing SH, Sancak Y, Cui X, Steine EJ, Miller JC, Tam P, Bartsevich VV, Meng X, Rupniewski I, Gopalan SM, Sun HC, Pitz KJ, Rock JM, Zhang L, Davis GD, Rebar EJ, Cheeseman IM, Yamamoto KR, Sabatini DM, Jaenisch R, Gregory PD, Urnov FD.

Genome Res. 2010 Aug;20(8):1133-42. doi: 10.1101/gr.106773.110. Epub 2010 May 27.

7.

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency.

Hanna J, Markoulaki S, Schorderet P, Carey BW, Beard C, Wernig M, Creyghton MP, Steine EJ, Cassady JP, Foreman R, Lengner CJ, Dausman JA, Jaenisch R.

Cell. 2008 Apr 18;133(2):250-64. doi: 10.1016/j.cell.2008.03.028. Erratum in: Cell. 2008 Jul 25;134(2):365.

8.

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R.

Genes Dev. 2007 Dec 1;21(23):3110-22.

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