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Items: 1 to 50 of 588

1.

Delay in diagnosing patients with right-sided glioblastoma induced by hemispheric-specific clinical presentation.

Baumann C, Tichy J, Schaefer JH, Steinbach JP, Mittelbronn M, Wagner M, Foerch C.

J Neurooncol. 2019 Nov 11. doi: 10.1007/s11060-019-03335-4. [Epub ahead of print]

PMID:
31713017
2.

Mild chronic perturbation of inhibition severely alters hippocampal function.

Sun MY, Ziolkowski L, Lambert P, Shu HJ, Keiser M, Rensing N, Warikoo N, Martinek M, Platnick C, Benz A, Bracamontes J, Akk G, Steinbach JH, Zorumski CF, Wong M, Mennerick S.

Sci Rep. 2019 Nov 11;9(1):16431. doi: 10.1038/s41598-019-52851-w.

3.

Adrenal Insufficiency in Patients with Corticosteroid-Refractory Cerebral Radiation Necrosis Treated with Bevacizumab.

Voss M, Batarfi A, Steidl E, Wagner M, Forster MT, Steinbach JP, Rödel CM, Bojunga J, Ronellenfitsch MW.

J Clin Med. 2019 Oct 3;8(10). pii: E1608. doi: 10.3390/jcm8101608.

4.

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF.

Di Tacchio M, Macas J, Weissenberger J, Sommer K, Bähr O, Steinbach JP, Senft C, Seifert V, Glas M, Herrlinger U, Krex D, Meinhardt M, Weyerbrock A, Timmer M, Goldbrunner R, Deckert M, Scheel AH, Büttner R, Grauer OM, Schittenhelm J, Tabatabai G, Harter PN, Günther S, Devraj K, Plate KH, Reiss Y.

Cancer Immunol Res. 2019 Oct 9. doi: 10.1158/2326-6066.CIR-18-0865. [Epub ahead of print]

PMID:
31597643
5.

Steady-state activation and modulation of the synaptic-type α1β2γ2L GABAA receptor by combinations of physiological and clinical ligands.

Germann AL, Pierce SR, Senneff TC, Burbridge AB, Steinbach JH, Akk G.

Physiol Rep. 2019 Sep;7(18):e14230. doi: 10.14814/phy2.14230.

6.

18F-FET PET imaging in differentiating glioma progression from treatment-related changes - a single-center experience.

Maurer GD, Brucker DP, Stoffels G, Filipski K, Filss CP, Mottaghy FM, Galldiks N, Steinbach JP, Hattingen E, Langen KJ.

J Nucl Med. 2019 Sep 13. pii: jnumed.119.234757. doi: 10.2967/jnumed.119.234757. [Epub ahead of print]

PMID:
31519802
7.

Second Generation mTOR Inhibitors as a Double-Edged Sword in Malignant Glioma Treatment.

Heinzen D, Divé I, Lorenz NI, Luger AL, Steinbach JP, Ronellenfitsch MW.

Int J Mol Sci. 2019 Sep 10;20(18). pii: E4474. doi: 10.3390/ijms20184474.

8.

Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.

Weller J, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Hau P, Krex D, Grauer O, Goldbrunner R, Bähr O, Uhl M, Seidel C, Tabatabai G, Brehmer S, Bullinger L, Galldiks N, Schaub C, Kebir S, Stummer W, Simon M, Fimmers R, Coch C, Glas M, Herrlinger U, Schäfer N.

Lancet Oncol. 2019 Oct;20(10):1444-1453. doi: 10.1016/S1470-2045(19)30502-9. Epub 2019 Sep 2.

PMID:
31488360
9.

EGFR and mTOR as therapeutic targets in glioblastoma.

Ronellenfitsch MW, Luger AL, Steinbach JP.

Oncotarget. 2019 Jul 30;10(46):4721-4723. doi: 10.18632/oncotarget.27094. eCollection 2019 Jul 30. No abstract available.

10.

Chemotherapy and diffuse low-grade gliomas: a survey within the European Low-Grade Glioma Network.

Darlix A, Mandonnet E, Freyschlag CF, Pinggera D, Forster MT, Voss M, Steinbach J, Loughrey C, Goodden J, Banna G, Di Blasi C, Foroglou N, Hottinger AF, Baron MH, Pallud J, Duffau H, Rutten GJ, Almairac F, Fontaine D, Taillandier L, Pessanha Viegas C, Albuquerque L, von Campe G, Urbanic-Purkart T, Blonski M.

Neurooncol Pract. 2019 Jul;6(4):264-273. doi: 10.1093/nop/npy051. Epub 2018 Dec 13.

11.

Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial.

Kebir S, Schaub C, Junold N, Hattingen E, Schäfer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Galldiks N, Weller J, Mack F, Tzaridis T, Bähr O, Seidel C, Schlegel U, Schmidt-Graf F, Rohde V, Borchers C, Tabatabai G, Hänel M, Sabel M, Gerlach R, Krex D, Belka C, Vatter H, Proescholdt M, Glas M, Herrlinger U.

J Neurooncol. 2019 Sep;144(3):501-509. doi: 10.1007/s11060-019-03246-4. Epub 2019 Jul 19.

PMID:
31325144
12.

Bedside Measurement of Volatile Organic Compounds in the Atmosphere of Neonatal Incubators Using Ion Mobility Spectrometry.

Steinbach J, Goedicke-Fritz S, Tutdibi E, Stutz R, Kaiser E, Meyer S, Baumbach JI, Zemlin M.

Front Pediatr. 2019 Jun 18;7:248. doi: 10.3389/fped.2019.00248. eCollection 2019.

13.

In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine - A Radioligand for Imaging σ1 Receptors With Positron Emission Tomography (PET).

Ludwig FA, Fischer S, Houska R, Hoepping A, Deuther-Conrad W, Schepmann D, Patt M, Meyer PM, Hesse S, Becker GA, Zientek FR, Steinbach J, Wünsch B, Sabri O, Brust P.

Front Pharmacol. 2019 Jun 13;10:534. doi: 10.3389/fphar.2019.00534. eCollection 2019.

14.

Steady-State Activation and Modulation of the Concatemeric α1β2γ2L GABAA Receptor.

Germann AL, Pierce SR, Burbridge AB, Steinbach JH, Akk G.

Mol Pharmacol. 2019 Sep;96(3):320-329. doi: 10.1124/mol.119.116913. Epub 2019 Jul 1.

PMID:
31263018
15.

Loss of cell-matrix contact increases hypoxia-inducible factor-dependent transcriptional activity in glioma cells.

Maurer GD, Brucker DP, Steinbach JP.

Biochem Biophys Res Commun. 2019 Jul 12;515(1):77-84. doi: 10.1016/j.bbrc.2019.05.115. Epub 2019 May 23.

PMID:
31128911
16.

Lack of H3K27 trimethylation is associated with 1p/19q codeletion in diffuse gliomas.

Filipski K, Braun Y, Zinke J, Roller B, Baumgarten P, Wagner M, Senft C, Zeiner PS, Ronellenfitsch MW, Steinbach JP, Plate KH, Gasparoni G, Mittelbronn M, Capper D, Harter PN.

Acta Neuropathol. 2019 Aug;138(2):331-334. doi: 10.1007/s00401-019-02025-9. Epub 2019 May 7. No abstract available.

17.

Repeat FMISO-PET imaging weakly correlates with hypoxia-associated gene expressions for locally advanced HNSCC treated by primary radiochemotherapy.

Löck S, Linge A, Seidlitz A, Bandurska-Luque A, Nowak A, Gudziol V, Buchholz F, Aust DE, Baretton GB, Zöphel K, Steinbach J, Kotzerke J, Overgaard J, Zips D, Krause M, Baumann M, Troost EGC.

Radiother Oncol. 2019 Jun;135:43-50. doi: 10.1016/j.radonc.2019.02.020. Epub 2019 Mar 9.

PMID:
31015169
18.

The influence of mode of anaesthesia for caesarean delivery on neonatal Apgar scores in the Czech Republic and Slovakia: secondary analysis of the results of an international survey in 2015.

Harazim H, Stourac P, Blaha J, Grochova M, Klozova R, Noskova P, Seidlova D, Richterova S, Svoboda M, Jarkovsky J, Silova X, Jezova B, Steinbach J, Zemanek M, Mannova J, Slavik J, Novakova Z, Misakova L, Firment J.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Jun;163(2):147-154. doi: 10.5507/bp.2019.008. Epub 2019 Apr 9.

19.

Correlation between FMISO-PET based hypoxia in the primary tumour and in lymph node metastases in locally advanced HNSCC patients.

Bandurska-Luque A, Löck S, Haase R, Richter C, Zöphel K, Perrin R, Appold S, Krause M, Steinbach J, Kotzerke J, Hofheinz F, Zips D, Baumann M, Troost EGC.

Clin Transl Radiat Oncol. 2019 Feb 15;15:108-112. doi: 10.1016/j.ctro.2019.02.002. eCollection 2019 Feb.

20.

Knockdown of the TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Sensitizes Glioma Cells to Hypoxia, Irradiation and Temozolomide.

Maurer GD, Heller S, Wanka C, Rieger J, Steinbach JP.

Int J Mol Sci. 2019 Mar 1;20(5). pii: E1061. doi: 10.3390/ijms20051061.

21.

Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.

Herrlinger U, Tzaridis T, Mack F, Steinbach JP, Schlegel U, Sabel M, Hau P, Kortmann RD, Krex D, Grauer O, Goldbrunner R, Schnell O, Bähr O, Uhl M, Seidel C, Tabatabai G, Kowalski T, Ringel F, Schmidt-Graf F, Suchorska B, Brehmer S, Weyerbrock A, Renovanz M, Bullinger L, Galldiks N, Vajkoczy P, Misch M, Vatter H, Stuplich M, Schäfer N, Kebir S, Weller J, Schaub C, Stummer W, Tonn JC, Simon M, Keil VC, Nelles M, Urbach H, Coenen M, Wick W, Weller M, Fimmers R, Schmid M, Hattingen E, Pietsch T, Coch C, Glas M; Neurooncology Working Group of the German Cancer Society.

Lancet. 2019 Feb 16;393(10172):678-688. doi: 10.1016/S0140-6736(18)31791-4. Epub 2019 Feb 14.

PMID:
30782343
22.

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.

Foltyn M, Luger AL, Lorenz NI, Sauer B, Mittelbronn M, Harter PN, Steinbach JP, Ronellenfitsch MW.

Br J Cancer. 2019 Mar;120(5):481-487. doi: 10.1038/s41416-018-0368-3. Epub 2019 Feb 12.

PMID:
30745581
23.

Contrast enhancing spots as a new pattern of late onset pseudoprogression in glioma patients.

Voss M, Franz K, Steinbach JP, Fokas E, Forster MT, Filipski K, Hattingen E, Wagner M, Breuer S.

J Neurooncol. 2019 Mar;142(1):161-169. doi: 10.1007/s11060-018-03076-w. Epub 2019 Jan 2.

PMID:
30604393
24.

Disruption of peroxisome proliferator-activated receptor γ coactivator (PGC)-1α reverts key features of the neoplastic phenotype of glioma cells.

Bruns I, Sauer B, Burger MC, Eriksson J, Hofmann U, Braun Y, Harter PN, Luger AL, Ronellenfitsch MW, Steinbach JP, Rieger J.

J Biol Chem. 2019 Mar 1;294(9):3037-3050. doi: 10.1074/jbc.RA118.006993. Epub 2018 Dec 21.

PMID:
30578297
25.

Application of the Co-Agonist Concerted Transition Model to Analysis of GABAA Receptor Properties.

Germann AL, Steinbach JH, Akk G.

Curr Neuropharmacol. 2019;17(9):843-851. doi: 10.2174/1570159X17666181206092418.

PMID:
30520374
26.

Distribution and prognostic impact of microglia/macrophage subpopulations in gliomas.

Zeiner PS, Preusse C, Golebiewska A, Zinke J, Iriondo A, Muller A, Kaoma T, Filipski K, Müller-Eschner M, Bernatz S, Blank AE, Baumgarten P, Ilina E, Grote A, Hansmann ML, Verhoff MA, Franz K, Feuerhake F, Steinbach JP, Wischhusen J, Stenzel W, Niclou SP, Harter PN, Mittelbronn M.

Brain Pathol. 2019 Jul;29(4):513-529. doi: 10.1111/bpa.12690. Epub 2019 Jan 15.

PMID:
30506802
27.

Fitting algorithms and baseline correction influence the results of non-invasive in vivo quantitation of 2-hydroxyglutarate with 1 H-MRS.

Wenger KJ, Hattingen E, Harter PN, Richter C, Franz K, Steinbach JP, Bähr O, Pilatus U.

NMR Biomed. 2019 Jan;32(1):e4027. doi: 10.1002/nbm.4027. Epub 2018 Nov 20.

PMID:
30457203
28.

The capability of commercial CFD code to predict organic peroxide fireball characteristics.

Blankenhagel P, Wehrstedt KD, Mishra KB, Steinbach J.

J Hazard Mater. 2019 Mar 5;365:386-394. doi: 10.1016/j.jhazmat.2018.11.011. Epub 2018 Nov 7.

PMID:
30448551
29.

Analysis of GABAA Receptor Activation by Combinations of Agonists Acting at the Same or Distinct Binding Sites.

Shin DJ, Germann AL, Covey DF, Steinbach JH, Akk G.

Mol Pharmacol. 2019 Jan;95(1):70-81. doi: 10.1124/mol.118.113464. Epub 2018 Oct 18.

PMID:
30337372
30.

Applying the Monod-Wyman-Changeux Allosteric Activation Model to Pseudo-Steady-State Responses from GABAA Receptors.

Steinbach JH, Akk G.

Mol Pharmacol. 2019 Jan;95(1):106-119. doi: 10.1124/mol.118.113787. Epub 2018 Oct 17. Review.

PMID:
30333132
31.

FMISO-PET-based lymph node hypoxia adds to the prognostic value of tumor only hypoxia in HNSCC patients.

Bandurska-Luque A, Löck S, Haase R, Richter C, Zöphel K, Abolmaali N, Seidlitz A, Appold S, Krause M, Steinbach J, Kotzerke J, Zips D, Baumann M, Troost EGC.

Radiother Oncol. 2019 Jan;130:97-103. doi: 10.1016/j.radonc.2018.09.008. Epub 2018 Oct 4.

PMID:
30293643
32.

Cochlear Implantation in Chronic Otitis Media: Investigation of Long-term Speech Comprehension and Rate of Complications.

Rak K, Völker J, Schendzielorz P, Kaulitz S, Steinbach J, Shehata-Dieler W, Schraven SP, Mlynski R, Radeloff A, Hagen R.

Otol Neurotol. 2018 Dec;39(10):e979-e984. doi: 10.1097/MAO.0000000000002026.

PMID:
30289846
33.

Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide.

Löser R, Bader M, Kuchar M, Wodtke R, Lenk J, Wodtke J, Kuhne K, Bergmann R, Haase-Kohn C, Urbanová M, Steinbach J, Pietzsch J.

Amino Acids. 2019 Feb;51(2):219-244. doi: 10.1007/s00726-018-2657-9. Epub 2018 Sep 27.

PMID:
30264172
34.

Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma.

Ronellenfitsch MW, Zeiner PS, Mittelbronn M, Urban H, Pietsch T, Reuter D, Senft C, Steinbach JP, Westphal M, Harter PN.

Acta Neuropathol Commun. 2018 Aug 21;6(1):81. doi: 10.1186/s40478-018-0583-4.

35.

Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet.

Voss M, Lorenz NI, Luger AL, Steinbach JP, Rieger J, Ronellenfitsch MW.

Int J Mol Sci. 2018 Aug 20;19(8). pii: E2462. doi: 10.3390/ijms19082462.

36.

Ventriculoperitoneal Shunts Equipped with On-Off Valves for Intraventricular Therapies in Patients with Communicating Hydrocephalus due to Leptomeningeal Metastases.

Burger MC, Wagner M, Franz K, Harter PN, Bähr O, Steinbach JP, Senft C.

J Clin Med. 2018 Aug 14;7(8). pii: E216. doi: 10.3390/jcm7080216.

37.

Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor.

Lindemann M, Hinz S, Deuther-Conrad W, Namasivayam V, Dukic-Stefanovic S, Teodoro R, Toussaint M, Kranz M, Juhl C, Steinbach J, Brust P, Müller CE, Wenzel B.

Bioorg Med Chem. 2018 Sep 1;26(16):4650-4663. doi: 10.1016/j.bmc.2018.07.045. Epub 2018 Jul 29.

PMID:
30104122
38.

Chemogenetic Isolation Reveals Synaptic Contribution of δ GABAA Receptors in Mouse Dentate Granule Neurons.

Sun MY, Shu HJ, Benz A, Bracamontes J, Akk G, Zorumski CF, Steinbach JH, Mennerick SJ.

J Neurosci. 2018 Sep 19;38(38):8128-8145. doi: 10.1523/JNEUROSCI.0799-18.2018. Epub 2018 Aug 3.

39.

Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation.

Heller S, Maurer GD, Wanka C, Hofmann U, Luger AL, Bruns I, Steinbach JP, Rieger J.

Int J Mol Sci. 2018 Jul 25;19(8). pii: E2168. doi: 10.3390/ijms19082168.

40.

Exploring pitfalls of 64Cu-labeled EGFR-targeting peptide GE11 as a potential PET tracer.

Striese F, Sihver W, Gao F, Bergmann R, Walther M, Pietzsch J, Steinbach J, Pietzsch HJ.

Amino Acids. 2018 Oct;50(10):1415-1431. doi: 10.1007/s00726-018-2616-5. Epub 2018 Jul 23.

PMID:
30039310
41.

From mono- to bivalent: improving theranostic properties of target modules for redirection of UniCAR T cells against EGFR-expressing tumor cells in vitro and in vivo.

Albert S, Arndt C, Koristka S, Berndt N, Bergmann R, Feldmann A, Schmitz M, Pietzsch J, Steinbach J, Bachmann M.

Oncotarget. 2018 May 22;9(39):25597-25616. doi: 10.18632/oncotarget.25390. eCollection 2018 May 22.

42.

Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial.

Schaub C, Kebir S, Junold N, Hattingen E, Schäfer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Niessen M, Mack F, Stuplich M, Tzaridis T, Bähr O, Kortmann RD, Schlegel U, Schmidt-Graf F, Rohde V, Braun C, Hänel M, Sabel M, Gerlach R, Krex D, Belka C, Vatter H, Proescholdt M, Herrlinger U, Glas M.

J Cancer Res Clin Oncol. 2018 Aug;144(8):1581-1589. doi: 10.1007/s00432-018-2671-z. Epub 2018 May 28.

PMID:
29808316
43.

Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems.

Luger AL, Sauer B, Lorenz NI, Engel AL, Braun Y, Voss M, Harter PN, Steinbach JP, Ronellenfitsch MW.

Int J Mol Sci. 2018 May 17;19(5). pii: E1504. doi: 10.3390/ijms19051504.

44.

Evaluation of Fluorine-18-Labeled α1(I)-N-Telopeptide Analogs as Substrate-Based Radiotracers for PET Imaging of Melanoma-Associated Lysyl Oxidase.

Kuchar M, Neuber C, Belter B, Bergmann R, Lenk J, Wodtke R, Kniess T, Steinbach J, Pietzsch J, Löser R.

Front Chem. 2018 Apr 26;6:121. doi: 10.3389/fchem.2018.00121. eCollection 2018.

45.

Synthesis, Characterization, and Initial Biological Evaluation of [99m Tc]Tc-Tricarbonyl-labeled DPA-α-MSH Peptide Derivatives for Potential Melanoma Imaging.

Gao F, Sihver W, Bergmann R, Belter B, Bolzati C, Salvarese N, Steinbach J, Pietzsch J, Pietzsch HJ.

ChemMedChem. 2018 Jun 6;13(11):1146-1158. doi: 10.1002/cmdc.201800110. Epub 2018 Apr 23.

PMID:
29659163
46.

Assessment of pre-operative maropitant citrate use in macaque (Macaca fasicularis & Macaca mulatta) neurosurgical procedures.

Steinbach JR, MacGuire J, Chang S, Dierks E, Roble GS.

J Med Primatol. 2018 Jun;47(3):178-184. doi: 10.1111/jmp.12343. Epub 2018 Apr 2.

PMID:
29611200
47.

Molecular Imaging in Oncology Using Positron Emission Tomography.

Derlin T, Grünwald V, Steinbach J, Wester HJ, Ross TL.

Dtsch Arztebl Int. 2018 Mar 16;115(11):175-181. doi: 10.3238/arztebl.2018.0175. Review.

48.

Chelation of heavy group 2 (radio)metals by p-tert-butylcalix[4]arene-1,3-crown-6 and logK determination via NMR.

Bauer D, Gott M, Steinbach J, Mamat C.

Spectrochim Acta A Mol Biomol Spectrosc. 2018 Jun 15;199:50-56. doi: 10.1016/j.saa.2018.03.029. Epub 2018 Mar 13. No abstract available.

PMID:
29567522
49.

Engrafting human regulatory T cells with a flexible modular chimeric antigen receptor technology.

Koristka S, Kegler A, Bergmann R, Arndt C, Feldmann A, Albert S, Cartellieri M, Ehninger A, Ehninger G, Middeke JM, Bornhäuser M, Schmitz M, Pietzsch J, Akgün K, Ziemssen T, Steinbach J, Bachmann MP.

J Autoimmun. 2018 Jun;90:116-131. doi: 10.1016/j.jaut.2018.02.006. Epub 2018 Mar 2.

PMID:
29503042
50.

Investigation of an 18F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A.

Schröder S, Wenzel B, Deuther-Conrad W, Teodoro R, Kranz M, Scheunemann M, Egerland U, Höfgen N, Briel D, Steinbach J, Brust P.

Molecules. 2018 Mar 2;23(3). pii: E556. doi: 10.3390/molecules23030556.

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