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Items: 1 to 50 of 66

1.

Duration of American football play and chronic traumatic encephalopathy.

Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC.

Ann Neurol. 2019 Oct 7. doi: 10.1002/ana.25611. [Epub ahead of print]

PMID:
31589352
2.

Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy.

Subramanian ML, Stein TD, Siegel N, Ness S, Fiorello MG, Kim D, Roy S.

Cells. 2019 Sep 21;8(10). pii: E1122. doi: 10.3390/cells8101122.

3.

Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy.

Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC.

JAMA Neurol. 2019 Aug 5. doi: 10.1001/jamaneurol.2019.2244. [Epub ahead of print]

PMID:
31380975
4.

Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set.

Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML.

Alzheimers Res Ther. 2019 Jul 27;11(1):64. doi: 10.1186/s13195-019-0521-0.

5.

Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy.

Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD.

Acta Neuropathol. 2019 Sep;138(3):401-413. doi: 10.1007/s00401-019-02031-x. Epub 2019 Jun 10.

PMID:
31183671
6.

Modelling human pathology of traumatic brain injury in animal models.

Risling M, Smith D, Stein TD, Thelin EP, Zanier ER, Ankarcrona M, Nilsson P.

J Intern Med. 2019 Jun;285(6):594-607. doi: 10.1111/joim.12909. Epub 2019 Apr 23.

PMID:
30963638
7.

Association of Cognitive Function with Amyloid-β and Tau Proteins in the Vitreous Humor.

Wright LM, Stein TD, Jun G, Chung J, McConnell K, Fiorello M, Siegel N, Ness S, Xia W, Turner KL, Subramanian ML.

J Alzheimers Dis. 2019;68(4):1429-1438. doi: 10.3233/JAD-181104.

PMID:
30856114
8.

Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia.

Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML.

Alzheimers Dement. 2019 May;15(5):686-698. doi: 10.1016/j.jalz.2018.12.015. Epub 2019 Mar 7.

PMID:
30852157
9.

Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy.

Signaevsky M, Prastawa M, Farrell K, Tabish N, Baldwin E, Han N, Iida MA, Koll J, Bryce C, Purohit D, Haroutunian V, McKee AC, Stein TD, White CL 3rd, Walker J, Richardson TE, Hanson R, Donovan MJ, Cordon-Cardo C, Zeineh J, Fernandez G, Crary JF.

Lab Invest. 2019 Jul;99(7):1019-1029. doi: 10.1038/s41374-019-0202-4. Epub 2019 Feb 15.

PMID:
30770886
10.

Association of Chronic Low-grade Inflammation With Risk of Alzheimer Disease in ApoE4 Carriers.

Tao Q, Ang TFA, DeCarli C, Auerbach SH, Devine S, Stein TD, Zhang X, Massaro J, Au R, Qiu WQ.

JAMA Netw Open. 2018 Oct 5;1(6):e183597. doi: 10.1001/jamanetworkopen.2018.3597.

11.

Cortical degeneration in chronic traumatic encephalopathy and Alzheimer's disease neuropathologic change.

Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ.

Neurol Sci. 2019 Mar;40(3):529-533. doi: 10.1007/s10072-018-3686-6. Epub 2018 Dec 18.

12.

The neuropathology of chronic traumatic encephalopathy.

Mckee AC, Abdolmohammadi B, Stein TD.

Handb Clin Neurol. 2018;158:297-307. doi: 10.1016/B978-0-444-63954-7.00028-8. Review.

PMID:
30482357
13.

Variation in TMEM106B in chronic traumatic encephalopathy.

Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, Meng G, Nowinski CJ, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Farrer LA, McKee AC, Stein TD.

Acta Neuropathol Commun. 2018 Nov 4;6(1):115. doi: 10.1186/s40478-018-0619-9.

14.

Reduced interleukin 1A gene expression in the dorsolateral prefrontal cortex of individuals with PTSD and depression.

Morrison FG, Miller MW, Wolf EJ, Logue MW, Maniates H, Kwasnik D, Cherry JD, Svirsky S, Restaino A, Hildebrandt A, Aytan N, Stein TD, Alvarez VE, McKee AC; Traumatic Stress Brain Study Group, Huber BR.

Neurosci Lett. 2019 Jan 23;692:204-209. doi: 10.1016/j.neulet.2018.10.027. Epub 2018 Oct 23.

PMID:
30366016
15.

Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort.

Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD.

J Neuropathol Exp Neurol. 2018 Dec 1;77(12):1091-1100. doi: 10.1093/jnen/nly092.

PMID:
30299493
16.

Astrocytic degeneration in chronic traumatic encephalopathy.

Hsu ET, Gangolli M, Su S, Holleran L, Stein TD, Alvarez VE, McKee AC, Schmidt RE, Brody DL.

Acta Neuropathol. 2018 Dec;136(6):955-972. doi: 10.1007/s00401-018-1902-3. Epub 2018 Sep 7.

PMID:
30194648
17.

Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports.

Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD.

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):757-768. doi: 10.1093/jnen/nly065.

18.

Cerebrospinal fluid tau, Aβ, and sTREM2 in Former National Football League Players: Modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration.

Alosco ML, Tripodis Y, Fritts NG, Heslegrave A, Baugh CM, Conneely S, Mariani M, Martin BM, Frank S, Mez J, Stein TD, Cantu RC, McKee AC, Shaw LM, Trojanowski JQ, Blennow K, Zetterberg H, Stern RA.

Alzheimers Dement. 2018 Sep;14(9):1159-1170. doi: 10.1016/j.jalz.2018.05.004. Epub 2018 Jul 23.

19.

A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology.

Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA.

J Alzheimers Dis. 2018;63(4):1347-1360. doi: 10.3233/JAD-180017.

20.

Age of first exposure to tackle football and chronic traumatic encephalopathy.

Alosco ML, Mez J, Tripodis Y, Kiernan PT, Abdolmohammadi B, Murphy L, Kowall NW, Stein TD, Huber BR, Goldstein LE, Cantu RC, Katz DI, Chaisson CE, Martin B, Solomon TM, McClean MD, Daneshvar DH, Nowinski CJ, Stern RA, McKee AC.

Ann Neurol. 2018 May;83(5):886-901. doi: 10.1002/ana.25245.

21.

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model.

Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV Jr, Kondo A, Zhou XZ, Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE, Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC, Goldstein LE.

Brain. 2018 Feb 1;141(2):422-458. doi: 10.1093/brain/awx350.

22.

Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study.

Mufson EJ, He B, Ginsberg SD, Carper BA, Bieler GS, Crawford F, Alvarez VE, Huber BR, Stein TD, McKee AC, Perez SE.

J Neurotrauma. 2018 Jun 1;35(11):1260-1271. doi: 10.1089/neu.2017.5368. Epub 2018 Apr 5.

23.

Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.

Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM.

J Neuropathol Exp Neurol. 2018 Jan 1;77(1):40-49. doi: 10.1093/jnen/nlx100.

24.

CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer's disease.

Cherry JD, Stein TD, Tripodis Y, Alvarez VE, Huber BR, Au R, Kiernan PT, Daneshvar DH, Mez J, Solomon TM, Alosco ML, McKee AC.

PLoS One. 2017 Sep 26;12(9):e0185541. doi: 10.1371/journal.pone.0185541. eCollection 2017.

25.

Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football.

Mez J, Daneshvar DH, Kiernan PT, Abdolmohammadi B, Alvarez VE, Huber BR, Alosco ML, Solomon TM, Nowinski CJ, McHale L, Cormier KA, Kubilus CA, Martin BM, Murphy L, Baugh CM, Montenigro PH, Chaisson CE, Tripodis Y, Kowall NW, Weuve J, McClean MD, Cantu RC, Goldstein LE, Katz DI, Stern RA, Stein TD, McKee AC.

JAMA. 2017 Jul 25;318(4):360-370. doi: 10.1001/jama.2017.8334.

26.

Transcriptome analyses of chronic traumatic encephalopathy show alterations in protein phosphatase expression associated with tauopathy.

Seo JS, Lee S, Shin JY, Hwang YJ, Cho H, Yoo SK, Kim Y, Lim S, Kim YK, Hwang EM, Kim SH, Kim CH, Hyeon SJ, Yun JY, Kim J, Kim Y, Alvarez VE, Stein TD, Lee J, Kim DJ, Kim JI, Kowall NW, Ryu H, McKee AC.

Exp Mol Med. 2017 May 19;49(5):e333. doi: 10.1038/emm.2017.56.

27.

Quantitative validation of a nonlinear histology-MRI coregistration method using generalized Q-sampling imaging in complex human cortical white matter.

Gangolli M, Holleran L, Hee Kim J, Stein TD, Alvarez V, McKee AC, Brody DL.

Neuroimage. 2017 Jun;153:152-167. doi: 10.1016/j.neuroimage.2017.03.059. Epub 2017 Mar 30.

28.

Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease.

Zhu H, Xue X, Wang E, Wallack M, Na H, Hooker JM, Kowall N, Tao Q, Stein TD, Wolozin B, Qiu WQ.

Neuropharmacology. 2017 Jun;119:170-181. doi: 10.1016/j.neuropharm.2017.03.030. Epub 2017 Mar 28.

29.

The Role of Substance P in Pulmonary Clearance of Bacteria in Comparative Injury Models.

Hsieh T, Vaickus MH, Stein TD, Lussier BL, Kim J, Stepien DM, Duffy ER, Chiswick EL, Remick DG.

Am J Pathol. 2016 Dec;186(12):3236-3245. doi: 10.1016/j.ajpath.2016.08.014.

30.

Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy.

Cherry JD, Tripodis Y, Alvarez VE, Huber B, Kiernan PT, Daneshvar DH, Mez J, Montenigro PH, Solomon TM, Alosco ML, Stern RA, McKee AC, Stein TD.

Acta Neuropathol Commun. 2016 Oct 28;4(1):112.

31.

Cognitive Reserve as a Modifier of Clinical Expression in Chronic Traumatic Encephalopathy: A Preliminary Examination.

Alosco ML, Mez J, Kowall NW, Stein TD, Goldstein LE, Cantu RC, Katz DI, Solomon TM, Kiernan PT, Murphy L, Abdolmohammadi B, Daneshvar D, Montenigro PH, Nowinski CJ, Stern RA, McKee AC.

J Neuropsychiatry Clin Neurosci. 2017 Winter;29(1):6-12. doi: 10.1176/appi.neuropsych.16030043. Epub 2016 Aug 19.

32.

Potential Long-Term Consequences of Concussive and Subconcussive Injury.

Huber BR, Alosco ML, Stein TD, McKee AC.

Phys Med Rehabil Clin N Am. 2016 May;27(2):503-11. doi: 10.1016/j.pmr.2015.12.007. Epub 2016 Feb 2. Review.

33.

Central nervous system involvement by myeloid sarcoma: a report of 12 cases and review of the literature.

Olar A, Lapadat R, Davidson CJ, Stein TD, Dahiya S, Perry A, Gheorghe G.

Clin Neuropathol. 2016 Sep-Oct;35(5):314-25. doi: 10.5414/NP300949. Review.

PMID:
27125868
34.

A quantitative study of tau pathology in 11 cases of chronic traumatic encephalopathy.

Armstrong RA, McKee AC, Stein TD, Alvarez VE, Cairns NJ.

Neuropathol Appl Neurobiol. 2017 Feb;43(2):154-166. doi: 10.1111/nan.12323. Epub 2016 Apr 15.

35.

Pathologically Confirmed Chronic Traumatic Encephalopathy in a 25-Year-Old Former College Football Player.

Mez J, Solomon TM, Daneshvar DH, Stein TD, McKee AC.

JAMA Neurol. 2016 Mar;73(3):353-5. doi: 10.1001/jamaneurol.2015.3998. No abstract available.

36.

Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy.

Kanaan NM, Cox K, Alvarez VE, Stein TD, Poncil S, McKee AC.

J Neuropathol Exp Neurol. 2016 Jan;75(1):19-34.

37.

The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy.

McKee AC, Cairns NJ, Dickson DW, Folkerth RD, Keene CD, Litvan I, Perl DP, Stein TD, Vonsattel JP, Stewart W, Tripodis Y, Crary JF, Bieniek KF, Dams-O'Connor K, Alvarez VE, Gordon WA; TBI/CTE group.

Acta Neuropathol. 2016 Jan;131(1):75-86. doi: 10.1007/s00401-015-1515-z. Epub 2015 Dec 14.

38.

Assessing clinicopathological correlation in chronic traumatic encephalopathy: rationale and methods for the UNITE study.

Mez J, Solomon TM, Daneshvar DH, Murphy L, Kiernan PT, Montenigro PH, Kriegel J, Abdolmohammadi B, Fry B, Babcock KJ, Adams JW, Bourlas AP, Papadopoulos Z, McHale L, Ardaugh BM, Martin BR, Dixon D, Nowinski CJ, Chaisson C, Alvarez VE, Tripodis Y, Stein TD, Goldstein LE, Katz DI, Kowall NW, Cantu RC, Stern RA, McKee AC.

Alzheimers Res Ther. 2015 Oct 12;7(1):62. doi: 10.1186/s13195-015-0148-8.

39.

Concussion in Chronic Traumatic Encephalopathy.

Stein TD, Alvarez VE, McKee AC.

Curr Pain Headache Rep. 2015 Oct;19(10):47. doi: 10.1007/s11916-015-0522-z. Review.

40.

Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage.

Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A.

Alzheimers Dement. 2015 Dec;11(12):1480-1488. doi: 10.1016/j.jalz.2015.04.009. Epub 2015 Jun 13.

41.

Beta-amyloid deposition in chronic traumatic encephalopathy.

Stein TD, Montenigro PH, Alvarez VE, Xia W, Crary JF, Tripodis Y, Daneshvar DH, Mez J, Solomon T, Meng G, Kubilus CA, Cormier KA, Meng S, Babcock K, Kiernan P, Murphy L, Nowinski CJ, Martin B, Dixon D, Stern RA, Cantu RC, Kowall NW, McKee AC.

Acta Neuropathol. 2015 Jul;130(1):21-34. doi: 10.1007/s00401-015-1435-y. Epub 2015 May 6.

42.

The neuropathology of chronic traumatic encephalopathy.

McKee AC, Stein TD, Kiernan PT, Alvarez VE.

Brain Pathol. 2015 May;25(3):350-64. doi: 10.1111/bpa.12248. Review.

43.

Post-traumatic neurodegeneration and chronic traumatic encephalopathy.

Daneshvar DH, Goldstein LE, Kiernan PT, Stein TD, McKee AC.

Mol Cell Neurosci. 2015 May;66(Pt B):81-90. doi: 10.1016/j.mcn.2015.03.007. Epub 2015 Mar 7. Review.

PMID:
25758552
44.

Chronic traumatic encephalopathy: historical origins and current perspective.

Montenigro PH, Corp DT, Stein TD, Cantu RC, Stern RA.

Annu Rev Clin Psychol. 2015;11:309-30. doi: 10.1146/annurev-clinpsy-032814-112814. Epub 2015 Jan 12. Review.

PMID:
25581233
45.

Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel.

Stein TD, Alvarez VE, McKee AC.

Alzheimers Res Ther. 2014 Jan 15;6(1):4. doi: 10.1186/alzrt234. eCollection 2014. Review.

46.

The neuropathology of sport.

McKee AC, Daneshvar DH, Alvarez VE, Stein TD.

Acta Neuropathol. 2014 Jan;127(1):29-51. doi: 10.1007/s00401-013-1230-6. Epub 2013 Dec 24. Review.

47.

A 34-year-old man with bitemporal hemianopsia.

Stein TD, Chae YS, Won N, Lee JH, Hedley-Whyte ET.

Brain Pathol. 2014 Jan;24(1):107-10. doi: 10.1111/bpa.12108. No abstract available.

PMID:
24345226
48.

The Department of Veterans Affairs Biorepository Brain Bank: a national resource for amyotrophic lateral sclerosis research.

Brady CB, Trevor KT, Stein TD, Deykin EY, Perkins SD, Averill JG, Guilderson L, McKee AC, Renner SW, Kowall NW.

Amyotroph Lateral Scler Frontotemporal Degener. 2013 Dec;14(7-8):591-7. doi: 10.3109/21678421.2013.822516. Epub 2013 Aug 23.

PMID:
23971854
49.

Clinical presentation of chronic traumatic encephalopathy.

Stern RA, Daneshvar DH, Baugh CM, Seichepine DR, Montenigro PH, Riley DO, Fritts NG, Stamm JM, Robbins CA, McHale L, Simkin I, Stein TD, Alvarez VE, Goldstein LE, Budson AE, Kowall NW, Nowinski CJ, Cantu RC, McKee AC.

Neurology. 2013 Sep 24;81(13):1122-9. doi: 10.1212/WNL.0b013e3182a55f7f. Epub 2013 Aug 21.

50.

Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology.

Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, Ikonomovic MD, López OL, Klunk W, Hyman BT, Gómez-Isla T.

Brain. 2013 Aug;136(Pt 8):2510-26. doi: 10.1093/brain/awt171. Epub 2013 Jul 3.

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